The study is the first to put antibiotic biosynthesis and resistance into an evolutionary context. The findings will help to guide the future discovery of new antibiotics and antibiotic alternatives which are medicines that are vitally needed given the current global threat of antimicrobial resistance.
The study examined the safety of place of birth by reporting on the risk of death at the time of birth or within the first four weeks, and found no clinically important or statistically different risk between home and hospital groups.
McMaster researchers have developed a novel new gel made entirely from bacteria-killing viruses. The anti-bacterial gel, which can be targeted to attack specific forms of bacteria, holds promise for numerous beneficial applications in medicine and environmental protection.
Scientists at McMaster University have identified new biomarkers for Irritable Bowel Syndrome (IBS) in urine, which could lead to better treatments and reduce the need for costly and invasive colonoscopy procedures currently used for diagnosis.
The human and economic costs of natural disasters, which many believe are becoming more frequent and more intense, are well known and well documented.
A team of researchers from McMaster University has mapped at atomic resolution a toxic protein linked to Alzheimer’s disease, allowing them to better understand what is happening deep within the brain during the earliest stages of the disease.
New findings of a multi-university research team show the pesticide DDT persists in remote lakes at concerning levels half a century after it was banned, affecting key aquatic species and potentially entire lake food webs.
Physical activity in early childhood may have an impact on cardiovascular health later in life, according to new research from McMaster University, where scientists followed the activity levels of hundreds of preschoolers over a period of years.
A clinical trial that followed more than 9,900 people in 24 countries has found that the drug dulaglutide reduced cardiovascular events and kidney problems in middle-aged and older people with Type 2 diabetes. During more than five years of follow-up, cardiovascular events like heart attacks and strokes were reduced by 12% in people taking dulaglutide compared to people taking a placebo. This effect was seen in both men and women with or without previous cardiovascular disease.
New research on the evolutionary relationships between tree sloths and their extinct giant relatives is challenging decades of widely accepted scientific research.
McMaster researchers have developed a simple and highly novel form of computing by shining patterned bands of light and shadow through different facets of a polymer cube and reading the combined results that emerge.
Researchers at McMaster University have invented a stable, affordable way to store fragile vaccines for weeks at a time at temperatures up to 40C, opening the way for life-saving anti-viral vaccines to reach remote and impoverished regions of the world.
An article on five facts about physician suicide, authored by Sarah Tulk and Joy Albuquerque was published today in the Canadian Medical Association Journal (CMAJ).
Health TAPESTRY is a community-based program anchored in primary care where trained volunteers visit older adults in their home. Volunteers use technology to gather information on their goals, needs, and risks, and a summary is sent to interprofessional primary care teams to plan patient care. The program combines new elements like technology with the current health system to support optimal aging in adults aged 70 years or older.
The 2014 OCHS study included 10,802 children and youth aged four to 17 in 6,537 families. It replicated and expanded on the landmark 1983 Ontario Child Health Study of 3,290 children in 1,869 families
Bhatia’s team spent more than six years delving down to the cellular level to examine what they say are previously overlooked cells that form on the edges of pluripotent stem cell colonies. Having characterised these cells, the team also observed them form at the earliest stages of pluripotent cell reprogramming from adult cells. By understanding and isolating these cells on the edges using a tool called single-cell RNA sequencing gene expression analysis, the researchers discovered a subset of cells with characteristics that made them different from the cellular ecosystem surrounding them.
Five facts about allergies to vaccines, pulled together by two McMaster University physicians.
The CANPWR study aims to identify what influences the success participants achieve in weight management programs and help improve these programs. The study follows participants for three years. The 10 clinics taking part in the study are in Vancouver, Edmonton, Calgary, Toronto, Hamilton, Ottawa and Montreal.
There are issues about the appropriateness of accepting or using MAID body donations; communication with donors including consenting processes, and the transparency surrounding MAID donation with staff, faculty and students.
Evolutionary biologists at McMaster University who study the social lives and behaviour of colony spiders—some of which are docile, others aggressive— have found that the success of their cooperative societies depend on their neighbours.
The study of evolution is revealing new complexities, showing how the traits most beneficial to the fitness of individual plants and animals are not always the ones we see in nature. Instead, new research by McMaster behavioural scientists shows that in certain cases evolution works in the opposite direction, reversing individual improvements to benefit related members of the same group.
The recovery has been broken into stages, and each stage outlines the goal, activities allowed and what to look for before moving to the next stage. For example, at stage two in getting back to school, children are allowed to walk, have 15 minutes of screen time or school work twice a day, and socialize with one or two friends for no more than 30 minutes.
An international team of researchers, which includes scientists from McMaster’s School of Geography & Earth Sciences, NASA, and others, is tackling one of the biggest problems of space travel to Mars: what happens when we get there?
McMaster researchers, working with partners at other universities, have created a motion-powered, fireproof sensor that can track the movements of firefighters, steelworkers, miners and others who work in high-risk environments where they cannot always be seen.
A preliminary diagnosis of Celiac disease in a child can be a stressful life event for an entire family. In addition to the prospect of following a completely gluten-free diet for life, a child must also face a series of tests – some invasive – to confirm the disease. While this should be a seamless and effective process, a recent study from McMaster University, The Hospital for Sick Children (SickKids) and William Osler Health System (Osler) shows this is not always the case. An additional, costly blood test is routinely prescribed and performed as part of the screening process and results of the study show it rarely predicts the disease.
Providing additional health-care services for heart failure patients to help them transition from hospital to home does not improve their outcome, according to research led by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences (HHS). The conclusion comes from a trial that followed the health status of almost 2,500 adults hospitalized for heart failure in hospitals across Ontario, Canada.
Nine out of 10 people who believe they’re allergic to the antibiotic either aren’t allergic or have only some intolerance, and eight of 10 people who had an allergic reaction to penicillin 10 or more years ago will now be fine.
Physicists at McMaster University have for the first time identified a simple mechanism used by potentially deadly bacteria to fend off antibiotics, a discovery which is providing new insights into how germs adapt and behave at a level of detail never seen before.
The benefits of exercise are widely known but kinesiologists at McMaster University have for the first time found that physical activity may help fight depression in seniors by stimulating muscle-generated mood boosters.
It just got harder to avoid exercise. A few minutes of stair climbing, at short intervals throughout the day, can improve cardiovascular health, according to new research from kinesiologists at McMaster University and UBC Okanagan.
A team of researchers from McMaster University has discovered a new technique to examine how musicians intuitively coordinate with one another during a performance, silently predicting how each will express the music.
The research team has demonstrated that anti-GRP78 autoantibodies can bind to GRP78 on the surface of lesion-resident endothelial cells and speed up atherosclerosis. The study also demonstrated that mouse models of atherosclerosis as well as patients with established cardiovascular disease have significantly elevated blood levels of these autoantibodies that both correlate and contribute to disease progression.
Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis (CF), a genetic disease which strikes both children and adults, causing chronic problems with the digestive system and the lungs.
McMaster University researchers reviewed 96 clinical trials with more than 26,000 participants and found opioids provide only small improvements in pain, physical functioning and sleep quality compared to a placebo.
Researchers at McMaster University have identified trends linking health and lifestyle factors like access to public transit, the variety of fresh fruits and vegetables in grocery stores, the prices of popular foods, the availability and prices of cigarettes and alcohol, and the promotion, or lack thereof, of healthy foods in restaurants. The study findings are based on detailed data collected across Canada’s 10 provinces.
The American Medical Association (AMA) Guides to the Evaluation of Permanent Impairment is used in workers' compensation systems, federal systems, automobile accidents and personal injury cases to rate impairment. However, a comparison of a group of injured workers assessed using the two most recent editions of the AMA guides revealed that usage of the sixth edition resulted in significantly lower impairment ratings than the fifth edition.
A new study examining differences in the language used in nearly 40-million tweets suggests national stereotypes—Canadians tend to be polite and nice while Americans are negative and assertive—are reflected on Twitter, even if those stereotypes aren’t necessarily accurate.
Tiny microscopic worms, invisible to the naked eye, are helping scientists to better understand an extraordinarily complex biological pathway that connects fat to overall health and aging in humans.
Gerry Wright, Director of the Michael G. DeGroote Institute for Infectious Disease Research, talking about the concern of antibiotic resistance (with infographic).
Researchers at McMaster University are warning that even short periods of inactivity in older people—as little as two weeks—can lead to worsening physical health, which could have a dramatic impact on an aging population.
A widely held and controversial myth that high-protein diets may cause kidney damage in healthy adults has been debunked by scientists at McMaster University, who examined more than two dozen studies involving hundreds of participants.
Researchers at McMaster University have solved a vexing problem by engineering surface coatings that can repel everything, such as bacteria, viruses and living cells, but can be modified to permit beneficial exceptions.
Comparing two strains of Salmonella – one that causes disease in humans and the other in reptiles – researchers discovered a covert way that the human-affecting bacteria essentially tricks the immune system into not attacking.
While exercise buffs have long used protein supplements to gain muscle, new research from McMaster University suggests one protein source in particular, whey protein, is most effective for seniors struggling to rebuild muscle lost from inactivity associated with illness or long hospital stays.
Samaan and his research team at McMaster set out to find studies on boys and girls under age 18 with exposure to recreational or medicinal cannabis. The use of cannabis included smoked, ingested and other modes of exposure to cannabis products.
McMaster researchers have pioneered one-of-a-kind technology that could – for the first time – provide experimental evidence of how life was formed on the early Earth and show whether life could have emerged elsewhere in the universe.
Given the increased use of progression-free survival as the primary outcome in new oncology drug trials, and uncertainty of overall survival, it remains possible that patients are receiving toxic and/or expensive treatments without experiencing important benefit.
For thousands of years, humans have relied on storytelling to engage, to share emotions and to relate personal experiences. Now, psychologists at McMaster University are exploring the mechanisms deep within the brain to better understand just what happens when we communicate.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right