Image courtesy of Rebecca C. Knickmeyer, PhD.
Impact of the APOE Alzheimer’s risk variant on the newborn brain. Blue clusters show decreased brain volumes in newborns with the risk variant. Similar decreases in this brain area, which is involved in memory, are seen in adults with the same variant. Yellow/orange clusters show increased brain volumes in newborns with the risk variant. These changes may be unique to infants and young children and could represent beneficial effects.