Using Low-Dose Irradiation, Researchers Can Now Edit Human Genes For the first time, researchers have employed a gene-editing technique involving low-dose irradiation to edit the genome of patient stem cells, according to a study published in the journal Stem Cells Translational Medicine. This method, developed by researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, is 10 times more effective than techniques currently in use.

“This novel technique allows for far more efficient gene editing of stem cells and will increase the speed of new discoveries in the field,” said co-senior author Clive Svendsen, PhD, director of the Board of Governors Regenerative Medicine Institute. CONTACT: Cara Martinez, 310-423-7798; Email [email protected]

Budding Scientists Do Hands-On Lab Work as Part of Summer Research Week Twenty-one Los Angeles high school students were at Cedars-Sinai the week of July 20 to participate in hands-on stem cell research and to get a jump-start on potential careers in scientific research. The students were part of the fourth annual Research Week program at the Cedars-Sinai Board of Governors Regenerative Medicine Institute. CONTACT: Soshea Leibler, 213-215-8000; Email [email protected].

African-Americans Face Twice the Rate of Sudden Cardiac Arrest, Compared to Caucasians
Compared to Caucasians, African-Americans face twice the rate of sudden cardiac arrest, according to a new study from the Cedars-Sinai Heart Institute. The study’s findings, published in the peer-reviewed journal Circulation, result from the first scientific analysis comparing the detailed medical history of patients of different races who were stricken by the usually fatal condition. Approximately 350,000 die every year from sudden cardiac arrest in the U.S. Link to Video: https://youtu.be/Aws-AYYcfl0 Link to Citation: http://circ.ahajournals.org/content/early/2015/07/08/CIRCULATIONAHA.115.015673.full.pdf+html CONTACT: Sally Stewart, 310-248-6566; Email [email protected]

“Wristwatch” Tracks Movements Every 2 Minutes to Help Doctors Monitor Parkinson’s Disease A simple motion sensor can open a door or alert a homeowner of an approaching intruder. Now, a much more sophisticated motion-detecting device the size, weight and shape of a wristwatch may help doctors at Cedars-Sinai evaluate the symptoms of their patients with Parkinson’s disease. Every two minutes, an unobtrusive device on Robert Yelin’s arm recorded the way his body was moving, and doctors at Cedars-Sinai used that data to evaluate and adjust his Parkinson’s disease medications. CONTACT: Sandy Van, 808-526-1708; Email [email protected]

# # #

Effective Sept. 1, 2015, the Cedars-Sinai neurosciences media contact will be Sally Stewart. [email protected].