Newswise — Bethesda, Md. (April 27, 2015)—Use of testosterone replacement therapy (TRT) to treat age-related testosterone deficiency has tripled over the past decade in the U.S., but its benefits remain controversial. A new review article by testosterone researchers at the University of Florida compared the modes of delivery and concluded that intramuscular injection of TRT conferred greater health benefits and lower cardiovascular risks than transdermal administration by skin patch or gel.

The article “Injection of Testosterone May Be Safer and More Effective than Transdermal Administration for Combatting Loss of Muscle and Bone in Older Men” is published ahead of print in the American Journal of Physiology—Endocrinology and Metabolism.

NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact Maggie Kuo at [email protected] or 301-634-7253.

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About the American Physiological Society (APS)Physiology is the study of how molecules, cells, tissues and organs function in health and disease. Established in 1887, the American Physiological Society (APS) was the first U.S. society in the biomedical sciences field. The Society represents more than 11,000 members and publishes 14 peer-reviewed journals with a worldwide readership.

Journal Link: American Journal of Physiology—Endocrinology and Metabolism, Apr-2015