Vaccinating Children Against HPV?

Released: 7-Jun-2013 12:00 PM EDT
Source Newsroom: Dana-Farber Cancer Institute
Expert Available
Contact Information

Available for logged-in reporters only

Newswise — BOSTON – The Human papillomavirus, or HPV, and its link to certain cancers has been in the headlines recently, reigniting the debate whether it is appropriate to vaccinate children against the virus.

Both the Centers for Disease Control and Prevention (CDC) and the American College of Pediatrics now recommend that both girls and boys be vaccinated against HPV. Robert I. Haddad, MD, disease center leader of Dana-Farber Cancer Institute’s head and neck oncology program, says the recommendations are well founded. “We are clearly seeing an epidemic of HPV-related head and neck cancer - the numbers are rising dramatically. HPV is a cause of many cancers, so it is really important to support endeavors to vaccinate.”

HPV has more than 100 strains, including HPV-16 and 18, which are aggressive, high-risk, sexually transmitted, and have been linked to certain types of cervical or head and neck cancers.

According to Haddad, HPV infection is a major cause of oropharyngeal cancer, which effects the base of the tongue, the tonsils, and the walls of the pharynx. This year, about 14,000 people in the United States will be diagnosed with oropharyngeal cancer. Most of them will be young , between 40 and 50 years old, and three out of four will be male.

“A decade ago, patients with head and neck cancer were smokers or heavy drinkers. Now, only 20 percent are smokers or drinkers, and the other 80 percent have an oropharynx cancer caused by an HPV infection,” says Haddad.

Because HPV is predominately transmitted through sexual contact, the CDC recommends vaccinating girls and boys at ages 11 or 12. The vaccine is given in three doses several months apart.

"I advise my patients with HPV-related cancers to vaccinate their children against HPV - both boys and girls,” says Haddad. “There is a misconception that only girls should be vaccinated and that is the wrong approach. We strongly believe that both boys and girls should be vaccinated against HPV."

In June 2006, The US Food and Drug Administration approved the use of the vaccine, Gardasil (Merck), for girls ages 9 to 26. The vaccine protects against four strains of HPV, including HPV-6 and -11, as well as the high risk strains HPV-16 and 18, which are a known cause of cervical, oropharyngeal, anal, and vaginal cancers. The CDC followed suit recommending the three dose vaccine become a routine immunization for girls. Gardasil was licensed for use in boys in October 2009. The CDC voted to approve it for boys in 2011.

More information can be found on Dana-Farber’s Insight blog post - Should Boys and Girls Be Vaccinated Against HPV?

About Dana-Farber Cancer Institute
Dana-Farber Cancer Institute (www.dana-farber.org) is a principal teaching affiliate of the Harvard Medical School and is among the leading cancer research and care centers in the United States. It is a founding member of the Dana-Farber/Harvard Cancer Center, designated a comprehensive cancer center by the National Cancer Institute. It provides adult cancer care with Brigham and Women’s Hospital as Dana-Farber/Brigham and Women’s Cancer Center and it provides pediatric care with Boston Children’s Hospital as Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. Dana-Farber is the top ranked cancer center in New England, according to U.S. News & World Report, and one of the largest recipients among independent hospitals of National Cancer Institute and National Institutes of Health grant funding. Follow Dana-Farber on Facebook: www.facebook.com/danafarbercancerinstitute and on Twitter: @danafarber.
# # #


Comment/Share