Newswise — The Venous Disease Coalition (VDC) presented the Coalition’s first annual Venous Disease Research Awards to the three leading research studies of venous disease at the Vascular Disease Foundation’s 2009 Awards Dinner in Washington, DC. These Research Awards honor the work of investigators and acknowledge the creation of new clinical research relevant to the understanding and/or treatment of venous diseases.

The Venous Research Award for Basic Science was presented to Fatiha Bouzeghrane, PhD, Interventional Neuroradiology Research Laboratory, CHUM Research Center–Notre-Dame Hospital in Montreal. Bouzeghrane and her colleagues were recognized for their work on the research study, “Deep vein thrombosis resolution is impaired in diet-induced type 2 diabetic mice,” published in the Journal of Vascular Surgery, December 2008; ___: 1574-1584. The study concluded that diet-induced type-2 diabetes may impair DVT resolution through altered inflammatory, fibrinolytic, and matrix metalloproteinases. Study co-authors include Xiaochun Zhang, MD, BSc; Guylaine Gevry, BSc; and Jean Raymond, MD.

The Venous Research Award for Clinical Outcomes was presented to Robert J. Glynn, ScD, Division of Preventive Medicine, Brigham and Women’s Hospital, Boston. Dr. Glynn and his colleagues were recognized for their work on the research study, “A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism,” published in the New England Journal of Medicine, 360;18, 1851-1861. The study concluded that in apparently healthy persons, Rosuvastatin significantly reduced the occurrence of symptomatic venous thromboembolism. Study co-authors include Eleanor Danielson, MIA; Francisco A.H. Fonseca, MD; Jacques Genest, MD; Antonio M. Gotto, Jr., MD; John J.P. Kastelein, MD; Wolfgang Koenig, MD; Peter Libby, MD; Alberto J. Lorenzatti, MD; Jean G. MacFadyen, BA; Børge G. Nordestgaard, MD; James Shepherd, MD; James T. Willerson, MD; and Paul M Ridker, MD.

Gregory A. Maynard, MD, MSc. received the Venous Research Award for Quality Improvement and Implementation of Best Practices. Dr. Maynard is the health science professor of Medicine, and Chief, Division of Hospital Medicine at the University of San Diego. He and his colleagues were recognized for their work on the research study, “Optimizing Prevention of Hospital-Acquired (HA) Venous Thromboembolism (VTE): Prospective Validation of a VTE Risk Assessment Model (RAM),” soon to be published in the Journal of Hospital Medicine.

The study, in part funded under grant number 1U18HS015826-01 from The Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services, validated a VTE risk-assessment/prevention protocol; improved VTE prophylaxis resulted in a substantial reduction in hospital-acquired VTE. The toolkits that allow others to achieve breakthrough performance have been published and are freely available on Society of Hospital Medicine and Agency for Healthcare Research and Quality. Co-authors include Timothy A. Morris, MD; Ian H. Jenkins, MD; Sarah Stone, MD; Joshua Lee, MD; Marian Renvall, MS; Ed Fink, MA; and Robert Schoenhaus, PharmD.

“On behalf of the Venous Disease Coalition, we are delighted to present these inaugural, prestigious awards to Drs. Bouzeghrane, Glynn and Maynard,” said Samuel Z. Goldhaber, MD, president of the Venous Disease Coalition, professor of medicine, Harvard Medical School, senior staff member of the Cardiovascular Medicine Division of Brigham and Women’s Hospital, and director of the Brigham and Women’s Hospital Venous Thromboembolism Research Group. “These research studies provide novel insight into the basic science of thrombogenesis, clinical outcomes in treating venous thromboembolism, and quality improvement and implementation of best practices in venous thromboembolism prevention,” said Dr. Goldhaber.

About the Venous Disease CoalitionThe Venous Disease Coalition (VDC) is a collaborative network of professional and public organizations united by one mission to increase public and health professional awareness of venous disease. The Coalition provides opportunities for members of the public, health care professionals, clinician investigators and basic researchers, professional health societies, government and health policy agencies, and other public and private organizations to work collaboratively to improve public health by providing educational programs regarding venous disease. For more information, visit www.venousdiseasecoalition.org.