Leonidas Stamatatos, who this month authored a paper on eliciting broadly neutralizing antibodies for the first time in the Journal of Experimental Medicine, is available to comment on new research in HIV vaccines and on his own recent paper.
BioFull Professor & Program Director, Seattle Biomedical Research InstituteAffiliate Professor, Department of Global Health, University of WashingtonArea of Expertise: HIV/AIDS, immunology, vaccinology
The emphasis of Leo Stamatatos’ work is to develop a safe and effective vaccine to combat the spread of HIV and to investigate how HIV infection leads to AIDS.
ResearchA major area of interest for Stamatatos' lab is to better understand how neutralizing antibodies against HIV are developed during natural HIV-infection, in a subset of individuals infected with HIV. They are particularly interested in:
• identifying immunological pathways that lead to the development of broadly neutralizing antibodies during natural HIV infection and exploit these pathways for vaccine-related purposes• understanding how the virus evolves to avoid the action of such antibodies• The Stamatotos group utilizes diverse approaches and iterative methodologies to design and test candidate HIV vaccines
Themes• HIV envelope structure/function relationship• B cell immunology in the conext of HIV infection• HIV evolutionary escape pathways and pathogenesis• HIV vaccine design
Stamatatos’ research is currently supported by the National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation.
RSS