Ohio State, Nationwide Children’s Hospital Partner with ENTvantage Diagnostics to Bring Rapid Sinusitis Diagnostic Test to Physicians
First-of-its-kind diagnostic kit for in-office, rapid diagnosing of bacterial sinusitis
Article ID: 622330
Released: 21-Aug-2014 1:00 PM EDT
Source Newsroom: Nationwide Children's Hospital
Newswise — COLUMBUS, Ohio, and AUSTIN, Texas-The Ohio State University, through the Ohio State Innovation Foundation, and Nationwide Children’s Hospital announced the signing of an exclusive, world-wide agreement with ENTvantage Diagnostics Inc. licensing a technology for rapid diagnosing of bacterial sinusitis. The jointly-created technology will be the foundation for ENTvantage Diagnostics Inc. to develop a diagnostic kit based on this technology to better equip physicians with additional information when making a bacterial sinusitis diagnosis.
The technology was developed as a result of the research collaboration between The Ohio State University and Nationwide Children’s Hospital. Subinoy Das, M.D. and Lauren O. Bakaletz, Ph.D., joined forces to create the diagnostic technology. Das is the former Director of The Ohio State University Sinus and Allergy Center and is now an adjunct Assistant Professor at The Ohio State University. In addition, he is a Research Associate of the Center for Microbial Pathogenesis in The Research Institute at Nationwide Children’s Hospital. Bakaletz is the Director of the Center for Microbial Pathogenesis in The Research Institute at Nationwide Children’s. She is a Professor in the Departments of Pediatrics and of Otolaryngology at The Ohio State University College of Medicine.
Determining the primary cause of sinusitis remains a clinical challenge for physicians. Different kinds of medication are often given to a patient until a specific medication is effective in improving the sinusitis condition. The diagnostic kit will enable physicians to take a sample swab from a patient’s nose, perform a rapid analysis, and have the results of the infection available the next day.
“Many patients are being prescribed antibiotics that they do not need or do not optimally treat the underlying pathogenic bacteria because there is a lack of definitive office-based diagnostic tests for this infection,” said Das. “This assay kit will help physicians understand the underlying bacterial cause of sinusitis in their office and allow better selection of antibiotics to treat patients. In addition to more efficient treatment, the diagnostic kit will also aid in reducing the number of antibiotic resistant infections and complications.”
“Our research serves as the foundation for this diagnostic test by demonstrating the specific bacterial protein profiles associated with chronic sinusitis. With the identification of these biomarkers, tests now can be developed to determine the presence and type of pathogenic bacteria in the upper respiratory tract,” Bakaletz explained. “Seeing our research result in a
positive impact on physician practice, and more importantly on patient health, is the aspiration of every medical scientist.”
Nationwide Children’s Hospital and Ohio State have a long-standing collaborative history and continue to work together on several fronts, one of which includes commercializing technologies. Both organizations have an equity position in ENTvantage Diagnostics Inc.
ENTvantage was founded by serial medical device entrepreneurs Joe Skraba and Rick Hawkins who bring more than 50 years of collective experience in commercialization of a broad range of medical devices, pharmaceuticals and biotech products. “Dr. Das and Dr. Bakaletz are thought leaders in their disciplines and the technology they created will truly change the diagnostic capabilities for bacterial sinusitis,” said Skraba. “Collaborating with Nationwide Children’s Hospital and Ohio State was a logical decision for ENTvantage.”
Austin-based ENTvantage plans to commercialize diagnostic tests to improve the diagnosis of illnesses of the ear, nose and throat by providing rapid, in-office diagnostic test kits to physicians world-wide.
“The lack of diagnostic tools has led physicians to over prescribe antibiotics to treat sinusitis when they are not needed, we know that we can provide physicians with timely information to better diagnose the underlying cause of these illnesses and lead to better management of sinusitis,” said Joe Skraba, the President & CEO of ENTvantage.
The implications of ENTvantage’ s diagnostic kit go well beyond bacterial sinusitis. “The same pathogens that cause bacterial sinusitis, also cause illnesses in other areas of the body, we believe we can extend this technology to identify these bacterial pathogens and lead to improved patient care, reduction of treatment costs and a reduction in the growing worldwide epidemic of antibiotic resistant infections,” said Skraba.
About The Ohio State University:Ohio State is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. Founded in 1870, The Ohio State University is a world-class public research university and the leading comprehensive teaching and research institution in the state of Ohio. With more than 63,000 students (including 57,000 in Columbus), the Wexner Medical Center, 14 colleges, 80 centers, and 175 majors, the university offers its students tremendous breadth and depth of opportunity in the liberal arts, the sciences, and the professions.
About Nationwide Children’s Hospital: Ranked in all 10 specialties in “U.S. News & World Report’s 2013-14 Best Children’s Hospitals” and among the Top 10 on Parents magazine’s 2013 “Best Children’s Hospitals” lists, Nationwide Children’s Hospital is one of the nation’s largest not-for-profit freestanding pediatric healthcare networks providing care for infants, children, adolescents and adult patients with congenital disease. As home to the Department of Pediatrics of The Ohio State University College of Medicine, Nationwide Children’s Hospital faculty train the next generation of pediatricians, scientists and pediatric specialists. The Research Institute at Nationwide Children’s Hospital is one of the top 10 National Institutes of Health-funded free-standing pediatric research facilities in the U.S., supporting basic, clinical, and translational and health services research at Nationwide Children’s Hospital.
About ENTvantage: ENTvantage Diagnostics Inc. based in Austin TX, develops and markets rapid, in-office diagnostic tests that provide primary care and ENT physicians with timely information on the causes of ear, nose and throat illnesses. The company’s first products will assist physicians to accurately diagnose bacterial sinusitis and lead to a reduction in inappropriate antibiotic prescriptions.
Contact:Melanie BakerMarketing and Communication ManagerThe Ohio State UniversityTechnology Commercialization Office614.292.9839 (Office)email@example.com