Latest results of Phase 2 study confirm high rate of response, remission
–University of Texas M. D. Anderson Cancer Center|2013-06-19
–Society of Gynecologic Oncology|2013-06-19
Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms (SNPs). The goal is to better predict a prostate cancer’s aggressiveness to avoid unnecessary radical treatment.
–Moffitt Cancer Center |2013-06-19
Highly sensitive and accurate test detects cancer-related microRNA in blood of patients even before the development of colorectal cancer.
–Baylor Health Care System|2013-06-19
Signal tells MCM7 to launch DNA replication; pathway reduces breast cancer patient survival
–University of Texas M. D. Anderson Cancer Center|2013-06-18
Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of aggressive breast cancer.
–University of Chicago Medical Center|2013-06-18
A recently published paper by the George Washington University Cancer Institute addresses the value of patient navigation programs for community cancer centers.
–George Washington University|2013-06-18
Dana-Farber researchers find many men with low-risk, localized prostate cancers can safely choose observation instead of undergoing immediate treatment and a have better quality of life while reducing health care costs.
–Dana-Farber Cancer Institute|2013-06-18
Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells in at least one pre-cancerous condition.
–University of California, San Francisco (UCSF)|2013-06-17
Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.
–National Cancer Institute (NCI) at NIH|2013-06-17
A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society’s 95th Annual Meeting in San Francisco.
–Endocrine Society|2013-06-17
A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function.
–University of California, San Diego Health Sciences|2013-06-17
Ubiquitous plasticizers may have long-term health effects.
–University of Illinois at Chicago|2013-06-17
Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new study finds. The results will be presented Monday, June 17, at The Endocrine Society’s 95th Annual Meeting in San Francisco.
–Endocrine Society|2013-06-17
A new molecular pathway involving the gene ZNF365 has been identified and abnormalities in that pathway may predict worse outcomes for patients with breast cancer, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.
–American Association for Cancer Research (AACR)|2013-06-17
Researchers have discovered a molecular switch that explains, at least in part, how some fast-growing prostate cancers become resistant to hormone treatment, a new study conducted in human cell cultures and mice finds. The results were presented Saturday at The Endocrine Society’s 95th Annual Meeting in San Francisco.
–Endocrine Society|2013-06-15
A new osteoporosis drug hinders the growth of estrogen-sensitive cancer that has become resistant to treatment with tamoxifen, a study in mice shows.
–Endocrine Society|2013-06-15
A new genetic test accurately and consistently diagnoses benign growths, or nodules, on the thyroid gland, according to a study from Chile.
–Endocrine Society|2013-06-15
A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.
–Duke Medicine|2013-06-15
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The Cancer News Source is a joint project by Newswise and the National Cancer Institute to promote cancer research news to the public and news media.
–National Cancer Institute (NCI) at NIH|2013-06-11
–National Cancer Institute (NCI) at NIH|2013-06-04
For Dario Altieri, M.D., the future of cancer medicine at The Wistar Institute reads something like a treatment for a superhero film. Dr. Altieri is director of Wistar’s NCI-designated Cancer…
–National Cancer Institute (NCI) at NIH|2013-06-11
Cancer immunotherapy is showing promise in treating patients with a variety of advanced, metastatic tumors, as evidenced by two newly unveiled studies from Yale Cancer Center.
–National Cancer Institute (NCI) at NIH|2013-06-03
 
- 4:38 PM June 19, 2013
Researchers from The University of Chicago report that fat cells in the breast m...Researchers from The University of Chicago report that fat cells in the breast may connect social stress to triple-negative #breastcancer. Study published in the July 2013 issue of the journal Cancer Prevention Research.
Possible connection of social stress and some breast cancers - National Cancer Institute
www.cancer.gov
Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago... - 1:12 PM June 18, 2013
A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer...A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted by the City of Hope. The results were presented at The Endocrine Society's 95th Annual Meeting in San Francisco.
New medication treats drug-resistant prostate cancer in the lab - National Cancer Institute
www.cancer.gov
A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model by the City of Hope, Beckman Research Institute, in Duarte, Calif. The results were pr... - 12:32 PM June 18, 2013
NCI News Note: Reforms speed initiation of NCI-sponsored clinical trialsNCI News Note: Reforms speed initiation of NCI-sponsored clinical trials
Reforms speed initiation of NCI-sponsored clinical trials - National Cancer Institute
cancer.gov
The process of opening a cancer clinical trial for patient accrual often takes years, and research has shown that trials which are slow to register patients often fail to finish. Following a thorough review, NCI’s Operational Efficiency Working Group prod... - 4:38 PM June 17, 2013
NIH scientists find promising biomarker for predicting HPV-related oropharynx ca...NIH scientists find promising biomarker for predicting HPV-related oropharynx cancer. Study published in the Journal of Clinical Oncology.
Scientists find promising predictor of HPV-related oropharynx cancer - National Cancer Institute
www.cancer.gov
Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.... - 3:04 PM June 17, 2013
Study by The Wistar Institute describes how the effectiveness of anti #melanoma...Study by The Wistar Institute describes how the effectiveness of anti #melanoma drugs can be increased by combining anti-cancer therapies with #diabetes drugs. Findings published in Cancer Cell.
Diabetes drug points way to overcoming melanoma drug resistance - National Cancer Institute
www.cancer.gov
Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer... - 9:48 AM June 17, 2013
Newly discovered genetic variations may help identify best candidates for preven...Newly discovered genetic variations may help identify best candidates for preventive #breastcancer drugs. Study published in the journal Cancer Discovery.
Using genetic variations to predict breast cancer risk - National Cancer Institute
cancer.gov
Newly discovered genetic variations may help predict breast cancer risk in women who receive preventive breast cancer therapy with the selective estrogen receptor modulator drugs tamoxifen and raloxifene, a Mayo Clinic-led study has found. The study is published in the journal Cancer Discovery.... - 12:28 PM June 13, 2013
Researchers at UCLA's Jonsson Comprehensive Cancer Center have found that bladde...Researchers at UCLA's Jonsson Comprehensive Cancer Center have found that bladder cancer recurrence and mortality could improve with better treatment compliance. Study published in American Cancer Society's journal Cancer.
Improving treatment compliance for bladder cancer - National Cancer Institute
cancer.gov
Researchers at UCLA’s Jonsson Comprehensive Cancer Center have found that the burden of bladder cancer on the population is very high, and that more intense surveillance and treatment in the first two years after diagnosis could reduce the number of patie... - 5:30 PM June 12, 2013
Researchers from the Indiana University Melvin and Bren Simon Cancer Center alo...Researchers from the Indiana University Melvin and Bren Simon Cancer Center along with colleagues from the Terry Fox Laboratory, BC Cancer Agency in Vancouver, Canada, have discovered how normal breast precursor cells may be genetically vulnerable to developing into cancer. Study published in Stem Cell Reports.
Researchers identify genetic risk for cancer in breast cells - National Cancer Institute
www.cancer.gov
Researchers from the Indiana University School of Medicine and its Melvin and Bren Simon Cancer Center, along with colleagues from the Terry Fox Laboratory, BC Cancer Agency in Vancouver, Canada, have discovered how normal breast precursor cells may be ge... - 4:35 PM June 12, 2013
A study by UC Davis Cancer Center examining trends in X-ray CT use in children h...A study by UC Davis Cancer Center examining trends in X-ray CT use in children has found that reducing unnecessary scans and lowering the doses for the highest-dose scans could lower the overall lifetime risk of future imaging-related cancers. Study published in JAMA Pediatrics.
Pediatric CT scans and associated cancer risk - National Cancer Institute
www.cancer.gov
A study examining trends in X-ray computed tomography (CT) use in children in the United States has found that reducing unnecessary scans and lowering the doses for the highest-dose scans could lower the overall lifetime risk of future imaging-related can... - 3:58 PM June 11, 2013
Eating healthy vegetable fats may improve prostate cancer survival, a new study...Eating healthy vegetable fats may improve prostate cancer survival, a new study led by UC San Francisco has found. Study published in JAMA Internal Medicine.
Diet changes may improve prostate cancer survival - National Cancer Institute
www.cancer.gov
Men with prostate cancer may significantly improve their survival chances with a simple change in their diet, a new study led by UC San Francisco (home of the UCSF Helen Diller Family Comprehensive Cancer Center) has found.... - 4:01 PM June 4, 2013
Researchers at the UCSD School of Medicine, with colleagues at the University of...Researchers at the UCSD School of Medicine, with colleagues at the University of Rochester Medical Center, have identified a new mechanism that appears to suppress tumor growth. Study published in PNAS.
Potential new way to suppress tumor growth - National Cancer Institute
www.cancer.gov
Researchers at the University of California, San Diego School of Medicine (home of the Moores Comprehensive Cancer Center), with colleagues at the University of Rochester Medical Center, have identified a new mechanism that appears to suppress tumor growt... - 11:30 AM June 4, 2013
According to results of a multicenter, pilot study led by investigators from Joh...According to results of a multicenter, pilot study led by investigators from Johns Hopkins University, there is no increased risk of infection for long-term sex partners of people with HPV-related oral cancers. Results of the study were presented at the 49th Annual Meeting of the American Society of Clinical Oncology.
Sex partners of people with HPV-related oral cancers and risk - National Cancer Institute
www.cancer.gov
Spouses and long-term partners of patients with mouth and throat cancers related to infection with the human papilloma virus (HPV) appear to have no increased prevalence of oral HPV infections, according to results of a multicenter, pilot study led by inv... - 10:28 AM June 4, 2013
Combination of drugs led to long-lasting tumor shrinkage in advanced melanoma pa...Combination of drugs led to long-lasting tumor shrinkage in advanced melanoma patients, according to results from a Phase I trial from Memorial Sloan-Kettering Cancer Center simultaneously published in The New England Journal of Medicine and presented at the 49th Annual Meeting of the American Society of Clinical Oncology.
Drug combination produces tumor response in advanced melanoma - National Cancer Institute
www.cancer.gov
The combination of the immunotherapy drug ipilimumab and the investigational antibody drug nivolumab led to long-lasting tumor shrinkage in more than half of patients with metastatic melanoma, according to results from a Phase I trial simultaneously publi... - 6:20 PM June 3, 2013
Cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as...Cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, presented by a researcher from the Perelman School of Medicine at the University of Pennsylvania and the Penn Medicine - Abramson Cancer Center in a plenary session during the American Society of Clinical Oncology's annual meeting.
Targeted therapy shows success in some thyroid cancer patients - National Cancer Institute
www.cancer.gov
The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, presented by a researcher from the Abramson Cancer Center and the Perelman Schoo... - 5:30 PM June 3, 2013
Research by Ohio State's James Cancer Hospital & Solove Research Institute and D...Research by Ohio State's James Cancer Hospital & Solove Research Institute and Dana-Farber Cancer Institute shows cytomegalovirus might speed the progression of brain cancer growth. Findings published in Cell Metabolism.
Cytomegalovirus might speed brain cancer growth - National Cancer Institute
www.cancer.gov
A virus that infects most Americans but that usually remains dormant in the body might speed the progression of an aggressive form of brain cancer when particular genes are shut off in tumor cells, new research shows. The animal study by researchers at th... - 4:50 PM June 3, 2013
Thousands of patients with an advanced form of lung cancer are likely to fare be...Thousands of patients with an advanced form of lung cancer are likely to fare better if treated with a targeted therapy than with traditional chemotherapy, report Dana-Farber Cancer Institute researchers and a team of international collaborators. Study published in The New England Journal of Medicine.
Targeted therapy boosts lung cancer outcomes - National Cancer Institute
www.cancer.gov
Thousands of patients with an advanced form of lung cancer that carries a specific dysfunctional gene are likely to fare better if treated with a targeted therapy than with traditional chemotherapy, report Dana-Farber Cancer Institute researchers and a te... - 4:13 PM June 3, 2013
Research teams led by Massachusetts General Hospital Cancer Center investigators...Research teams led by Massachusetts General Hospital Cancer Center investigators are publishing two important studies regarding the use of the targeted cancer drug crizotinib for treatment of advanced lung cancer. Both papers are being published in the The New England Journal of Medicine to coincide with the American Society of Clinical Oncology annual meeting.
Studies shed new light on targeted lung cancer therapy - National Cancer Institute
www.cancer.gov
Research teams led by Massachusetts General Hospital (MGH) Cancer Center (a component of the Dana-Farber Cancer Institute) investigators are publishing two important studies regarding use of the targeted cancer drug crizotinib for treatment of advanced lu... - 2:00 PM May 22, 2013
Trends in H. pylori and smoking explain a significant proportion of the decline...Trends in H. pylori and smoking explain a significant proportion of the decline of gastric cancer incidence in men, according to a Harvard School of Public Health study. Study published in PLoS Medicine.
H. pylori, smoking trends, and gastric cancer in U.S. men - National Cancer Institute
www.cancer.gov
Trends in Helicobacter pylori (H. pylori) and smoking explain a significant proportion of the decline of intestinal-type noncardia gastric adenocarcinoma (NCGA) incidence in U.S. men between 1978 and 2008, and are estimated to continue to contribute to fu... - 1:00 PM May 22, 2013
Investigators at Massachusetts General Hospital and Massachusetts Eye and Ear In...Investigators at Massachusetts General Hospital and Massachusetts Eye and Ear Infirmary show that genetic diversity predicts outcomes in head and neck cancer. Study published in American Cancer Society's journal Cancer.
Genetic diversity predicts outcomes in head and neck cancer - National Cancer Institute
cancer.gov
A new measure of the heterogeneity – the variety of genetic mutations – of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer. In the May 20 issue of the journal Cancer, investigators... - 11:49 AM May 22, 2013
Researchers from Salk Institute for Biological Studies, University of Southern C...Researchers from Salk Institute for Biological Studies, University of Southern California and UC Irvine suspect hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. Study published in PNAS.
Timing of cancer radiation therapy may minimize hair loss - National Cancer Institute
cancer.gov
Discovering that mouse hair has a circadian clock -- a 24-hour cycle of growth followed by restorative repair -- researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given... - 2:03 PM May 20, 2013
Researchers at Mayo Clinic have developed a promising method to distinguish betw...Researchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis. The findings were being presented at Digestive Disease Week® (DDW®) 2013 in Orlando, Fla.
Molecular marker helps identify pancreatic cancer - National Cancer Institute
www.cancer.gov
Researchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis — two disorders that are difficult to tell apart. A molecular marker obtained from pancreatic "juices" can identify almost all c... - 2:00 PM May 17, 2013
Most cancer patients would like to talk about the cost of care with their doctor...Most cancer patients would like to talk about the cost of care with their doctors, but often don't because they fear the discussion could compromise the quality of their treatment, researchers at Duke Cancer Institute report. Study being presented at the 2013 annual meeting of the American Society of Clinical Oncology.
Cancer patients want to discuss financial concerns with doctors - National Cancer Institute
www.cancer.gov
Most cancer patients would like to talk about the cost of their care with their doctors, but often don't because they fear the discussion could compromise the quality of their treatment, researchers at Duke Cancer Institute report. Yet many patients who d... - 1:00 PM May 17, 2013
People who have non-melanoma skin cancer may be less likely to develop Alzheimer...People who have non-melanoma skin cancer may be less likely to develop Alzheimer's disease, according to research carried out by scientists at Albert Einstein College of Medicine of Yeshiva University. Study published in the journal of the American Academy of Neurology.
Skin cancer linked to reduced risk for Alzheimer's disease - National Cancer Institute
cancer.gov
People who have non-melanoma skin cancer may be less likely to develop Alzheimer's disease, according to research carried out by scientists at Albert Einstein College of Medicine of Yeshiva University (home to the Albert Einstein Cancer Center). Their fin... - 12:00 PM May 17, 2013
Researchers at Georgetown Lombardi Comprehensive Cancer Center show that continu...Researchers at Georgetown Lombardi Comprehensive Cancer Center show that continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, but some tumors also regressed to the point that cancer cells could not be detected microscopically. Results will be presented at the 2103 annual meeting of the American Society of Clinical Oncology.
Agent stops certain proteins from binding, causing Ewing sarcoma - National Cancer Institute
cancer.gov
Continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, while some tumors also regressed to the point that cancer cells could not be detected microscopically, say researchers at Georgetown Lombardi Comprehensive Canc... - 11:09 AM May 17, 2013
A clinical trial has shown that patients were willing to undergo an additional c...A clinical trial has shown that patients were willing to undergo an additional cancer biopsy, to seek out the best treatment for their tumor type. Results of the study, CUSTOM, are being presented at the 2013 annual meeting of the American Society of Clinical Oncology by Georgetown Lombardi Comprehensive Cancer Center experts.
Trial shows molecular profiling timely for tailoring therapy - National Cancer Institute
cancer.gov
A clinical trial has shown that patients were willing to undergo an additional cancer biopsy, to seek out the best treatment for their tumor type through analysis to find and target genetic mutations that drive the cancer. Results of the study, CUSTOM, be... - 4:00 PM May 15, 2013
A new study from the University of Michigan and the University of Texas Medical...A new study from the University of Michigan and the University of Texas Medical Branch in Galveston shows primary care physicians vital to complete care of prostate cancer patients. Study published in the Journal of General Internal Medicine.
Primary care physicians vital to complete prostate cancer care - National Cancer Institute
www.cancer.gov
Androgen deprivation therapy is a common and effective treatment for advanced prostate cancer. However, among other side-effects, it can cause significant bone thinning in men on long-term treatment. A new study from the University of Michigan (home to th... - 2:42 PM May 15, 2013
A new finding from Massachusetts Institute of Technology (MIT) and David H. Koch...A new finding from Massachusetts Institute of Technology (MIT) and David H. Koch Institute for Integrative Cancer Research identifies key protein for cell death. Study published in Genes & Development.
Study identifies key protein for cell death - National Cancer Institute
www.cancer.gov
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA. A new finding from MIT’s Cen... - 3:17 PM May 13, 2013
A new study by Perelman School of Medicine at the University of Pennsylvania loo...A new study by Perelman School of Medicine at the University of Pennsylvania looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer. Study published in Nature Genetics.
Four new genetic risk factors for testicular cancer - National Cancer Institute
www.cancer.gov
A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today. The findings from this first-of-its-kind meta-anal... - 2:17 PM May 13, 2013
Patients with two forms of leukemia, who currently have no viable treatment opti...Patients with two forms of leukemia, who currently have no viable treatment options, may benefit from existing drugs developed for different types of cancer, according to a study conducted by researchers at the OHSU Knight Cancer Institute. The study is published in the The New England Journal of Medicine.
Discovery pinpoints cause of two types of leukemia - National Cancer Institute
www.cancer.gov
Patients with two forms of leukemia, who currently have no viable treatment options, may benefit from existing drugs developed for different types of cancer, according to a study conducted by researchers at the Knight Cancer Institute at Oregon Health & Science University (OHSU). The study, publishe......
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