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Study Finds a New Way to Shut Down Cancer Cells’ Ability to Consume Glucose

Many cancers depend on glucose consumption for energy, but good pharmacological targets to stop cancers’ ability to uptake and metabolize glucose are missing. CU Cancer Center study finally identifies a way to restrict the ability of cancer to use...
7-Nov-2017 11:05 AM EST Add to Favorites

Important New Insights Into RECIST Criteria Measuring Cancer’s Response to Treatment


CU Cancer Center study examines current RECIST guidelines in an effort to bring them up to speed with new complexities presented by the latest targeted therapies.
6-Nov-2017 4:35 PM EST Add to Favorites

In the Lab and in the Clinic, Alisertib with TAK-228 Excels Against Solid Tumors, Including Triple-Negative Breast Cancer


Two University of Colorado Cancer Center studies presented this weekend at AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Meeting show that using the drug alisertib along with the drug TAK-228 is more effective against triple-negative...
1-Nov-2017 11:05 AM EDT Add to Favorites

Tarloxitinib Puts Tumor-Seeking Tail on Anti-EGFR Drug to Precisely Target Lung Cancer

University of Colorado Cancer Center study being presented October 28 at the AACR-NCI-EORTC International Conference on Molecular Targets: By pairing an anti-EGFR drug with a “tail” that only activates the drug when it is very near tumor cells,...
24-Oct-2017 12:05 PM EDT Add to Favorites

Lung Cancer Driver ALK-Fusion Found in Melanoma

University of Colorado Cancer Center study finds a genetic change called ALK-fusion in a patient sample of a melanoma subtype called mucosal melanoma. When researchers treated a tumor grown from this sample with the drugs crizotinib and ceritinib...
23-Oct-2017 2:05 PM EDT Add to Favorites

Researchers Watch in Real Time as Fat-Encased Drug Nanoparticles Invade Skin Cells

Some anti-cancer drugs are encapsulated to allow gradual release, spreading their effect over a longer time. For example, one formulation of the chemotherapy doxorubicin ( the FDA-approved drug Doxil®) encloses molecules of the drug in fatty...
18-Oct-2017 4:05 PM EDT Add to Favorites

P53 “Master Switch” Remains Top Target in Gene Signaling Network Controlling Cancer Suppression

“People have always been after the silver bullet against cancer and there are few things that are as relevant across cancer types as p53. Now the question is what is the best approach to harness it,” says senior author Joaquin Espinosa, PhD.
9-Oct-2017 2:05 PM EDT Add to Favorites

Blood Tumor Markers May Warn When Lung Cancer Patients Are Progressing on Targeted Treatments

University of Colorado Cancer Center study shows that monitoring levels of blood tumor markers may predict when a lung cancer patient is progressing on targeted treatments.
6-Sep-2017 12:05 PM EDT Add to Favorites

Our Experts on Newswise

Will One Bad Sunburn Give You Skin Cancer?


27-Jul-2015 11:05 AM EDT

Oncologists: How to Talk With Your Pathologist About Cancer Molecular Testing


An education session presented today at the American Society for Clinical Oncology (ASCO) Annual Meeting 2014 details the challenges of collaboration between oncologists and pathologists in the context of molecular testing patient tumor samples.
30-May-2014 4:00 PM EDT

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