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Anticancer Agent FL118 More Potent than its Analogs, Not Prone to Typical Channels of Resistance

Researchers from Roswell Park Cancer Institute have reported findings about a new synthetic form of camptothecin that appears to have greater potency, longer efficacy and fewer adverse side effects than irinotecan and topotecan.
25-Nov-2015 11:05 AM EST Add to Favorites

Mathematical Modeling Can Help Predict Impact of Surgery on Cancer Metastasis


Scientists at Roswell Park Cancer Institute and Inria demonstrate that mathematical models can provide useful clues about the impact of surgery on metastasis, and may help to predict the risk of cancer spread.
24-Nov-2015 9:05 AM EST Add to Favorites

Scientists Identify Strategy to Prevent Renal Failure, Also Hit on Opportunities to Improve Cancer Treatment

Researchers have identified 10 genes whose inhibition appears to protect kidney cells. The findings point the way to strategies for preventing acute kidney injury and may also help to evade drug resistance in cancer therapy.
24-Nov-2015 9:05 AM EST Add to Favorites

International Team of Researchers Reports Promising Results in Study of Pediatric Neuroblastoma

Scientists from the Children’s Cancer Institute–Australia, Roswell Park Cancer Institute and Incuron LLC have identified a new treatment approach for a highly aggressive and usually fatal subtype of neuroblastoma.
6-Nov-2015 1:05 PM EST Add to Favorites

New Pediatric Cancer Chief Will Head Joint Program at Women & Children’s, Roswell Park and UB

Kara Kelly, MD has been appointed as the new leader of the joint program in pediatric hematology/oncology at Women & Children’s Hospital of Buffalo, Roswell Park Cancer Institute, UBMD Pediatrics and the University at Buffalo
26-Oct-2015 12:05 PM EDT Add to Favorites

Special Class of T Cells Shown to Both Attack Cancer Cells and Enlist Other Immune Cells

Writing in Scientific Reports, researchers led by a group from Roswell Park Cancer Institute have shared new insights about a subset of T cells that appear to both inhibit cancer growth and enhance the tumor-killing powers of other immune cells.
15-Oct-2015 10:45 AM EDT Add to Favorites

Treatment-Free Intervals in Ovarian Cancer Not Linked to Initial Response

Three-quarters of women treated for ovarian cancer face relapse of their disease. And while those who respond well to initial therapy do tend to survive longer, they require additional treatment for recurring cancer just as frequently as other women...
30-Sep-2015 10:05 AM EDT Add to Favorites

Study Reveals Generational Gap on Cessation Among Poor Rural Smokers in Northern Appalachia

Significant differences in attitudes toward smoking cessation are reported between two generations of smokers in Northern Appalachia in new research from Roswell Park Cancer Institute (RPCI). The qualitative study about beliefs, attitudes and...
10-Sep-2015 12:05 PM EDT Add to Favorites

Our Experts on Newswise

Roswell Park's Dr. James Marshall Available to Interpret, Comment on Who Statement on Processed Meats and Cancer Risk

27-Oct-2015 5:05 PM EDT

Cancer-Specific Clinical Research Center: New Frontiers in Research at Roswell Park

Clinical trials are the frontier for targeted cancer drugs. Roswell Park Cancer Institute recently opened one of only a few clinical research centers in the U.S. focused exclusively on cancer. The Clinical Research Center, under the direction of...
4-Apr-2008 1:00 PM EDT

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