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Genetic Body/Brain Connection Identified in Genomic Region Linked to Autism

For the first time, scientists have directly linked deletions in two genes in zebrafish and traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes are in a genome region linked to autism spectrum disorder,...
6-Oct-2017 3:05 PM EDT Add to Favorites

Mystery Solved: How Thyroid Hormone Prods Red Blood Cell Production

For more than a century, the link between thyroid hormone and red blood cell production has remained elusive. Now, Whitehead scientists have teased about the mechanism that connects them, which could help scientists identify new therapies for...
5-Sep-2017 12:05 PM EDT Add to Favorites

Whitehead Member David Sabatini Awarded Dickson Prize in Medicine

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Whitehead Institute Member David Sabatini will be this year’s recipient of the Dickson Prize in Medicine. The annual award is the University of Pittsburgh School of Medicine’s highest honor and recognizes “an American biomedical researcher...
17-Aug-2017 11:05 AM EDT Add to Favorites

Elegant Switch Controls Translation in Transition From Egg to Embryo

The transition from an egg to a developing embryo is one of life’s most remarkable transformations. Now Whitehead Institute researchers have used fruit flies to decipher how one aspect—control of the translation of messenger RNAs (mRNAs) into...
14-Jun-2017 5:10 PM EDT Add to Favorites

Whitehead’s Weng Receives Grant From Family Larsson-Rosenquist Foundation to Study Herbs That May Boost Mothers’ Milk

Many cultures traditionally use herbs believed to increase milk supply – so called galactagogues – although scientific data are lacking. Now Whitehead Institute Member Jing-Ke Weng and the Family Larsson-Rosenquist Foundation are teaming up to...
8-Jun-2017 10:00 AM EDT Add to Favorites

Biomarker Identified for Likely Aggressive, Early Stage Breast Cancer

Whitehead Institute scientists have identified a gene that could help clinicians discern which patients have aggressive forms of early stage breast cancer, which could prevent hundreds of thousands of women from undergoing unnecessary treatment and...
3-Apr-2017 10:05 AM EDT Add to Favorites

Cargo-Carrying Red Blood Cells Alleviate Autoimmune Diseases in Mice

Using red blood cells modified to carry disease-specific antigens, scientists from Whitehead Institute and Boston Children’s Hospital have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early...
6-Mar-2017 2:05 PM EST Add to Favorites

Researchers Uncover a Role for HSP90 in Gene-Environment Interactions in Humans

Researchers at Whitehead Institute have now uncovered a role for the protein-folding chaperone HSP90 in humans, not only as a modifier of the effects of mutations, but as a mediator of the impact of the environment on the function of mutant...
23-Feb-2017 10:00 AM EST Add to Favorites

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