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Discovery May Advance Neural Stem Cell Treatments for Brain Disorders


New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer’s disease,...
24-Jan-2018 9:00 AM EST Add to Favorites

Gut Reaction: Repeated Food Poisoning Triggers Chronic Disease


Small bacterial infections that may go unnoticed and which the body easily clears without treatment, such as occurs during mild food poisoning, nevertheless can start a chain of events that leads to chronic inflammation and potentially...
21-Dec-2017 2:00 PM EST Add to Favorites

Researchers Track Muscle Stem Cell Dynamics in Response to Injury and Aging

A new study led by SBP describes the biology behind why muscle stem cells respond differently to aging or injury. The findings, published in Cell Stem Cell, have important implications for the normal wear and tear of aging.
13-Dec-2017 4:35 PM EST Add to Favorites

Insights on How SHARPIN Promotes Cancer Progression


SBP and Technion Institute researchers have SHARPIN-ed their knowledge of how a malicious form of a protein drives the formation of melanoma through modulation of the PRMT5 pathway. The new research was published in The Journal of Clinical...
11-Dec-2017 4:00 PM EST Add to Favorites

Research Suggests New Pathways for Hyperaldosteronism


Scientists have identified a mechanism that explains the development of hyperaldosteronism, a condition in which the adrenal glands produce too much aldosterone, The findings, published in JCI Insight, offer a path for drug discovery to treat the...
7-Dec-2017 9:05 AM EST Add to Favorites

D’Angelo Receives American Cancer Society Research Scholar Grant

Maximiliano D’Angelo, Ph.D., an assistant professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), has received a four-year, $792,000 Research Scholar Grant from the American Cancer Society.
1-Dec-2017 5:00 AM EST Add to Favorites

Scientists Find Key to Regenerating Blood Vessels


Florida researchers have identified a signaling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels. The findings, published in Nature Communications, may improve current strategies to improve blood...
20-Nov-2017 2:00 PM EST Add to Favorites

Preclinical Study Demonstrates Promising Treatment for Rare Bone Disease


Researchers have demonstrated that the drug palovarotene suppresses the formation of bony tumors (osteochondromas) in models of multiple hereditary exostoses (MHE). The research, published in the Journal of Bone and Mineral Research, is an important...
21-Nov-2017 9:00 AM EST Add to Favorites

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