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Noncoding Mutations Disrupt Cooperative Function of ‘Gene Families’ in Rare Genetic Disorder

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Scientists say they are one step closer to understanding the genetic mechanism of a rare, complex, multiple-gene disorder called Hirschsprung’s disease. Their results suggest that many patients develop the disease when multiple mutations in gene...
30-Sep-2016 10:05 AM EDT Add to Favorites

New Treatment Strategy Could Cut Parkinson’s Disease Off at the Pass

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Researchers at Johns Hopkins report they have identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal’s brain — and a way to block that protein’s action. Their study in mice and cultured cells...
26-Sep-2016 10:00 AM EDT Add to Favorites

New Evidence That Testosterone May Explain Sex Difference in Knee Injury Rates

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In studies on rats, Johns Hopkins Medicine scientists report new evidence that the predominance of the hormone testosterone in males may explain why women are up to 10 times more likely than men to injure the anterior cruciate ligament (ACL) in...
20-Sep-2016 8:00 AM EDT Add to Favorites

Ensuring Transparency in Health Care Provider Performance

Patients deserve valid and transparent measures of quality in health care, but a lack of standards and auditing for these measures can misinform consumers rather than guide their health care choices, say researchers from the Johns Hopkins Armstrong...
19-Sep-2016 1:40 PM EDT Add to Favorites

MRI Guidance Shows Promise in Delivering Stem Cell Therapies

Working with animals, a team of scientists reports it has delivered stem cells to the brain with unprecedented precision by threading a catheter through an artery and infusing the cells under real-time MRI guidance.
14-Sep-2016 9:00 AM EDT Add to Favorites

Computer Algorithm Illuminates Need of High-Volume Hospitals and Standard Care for Transplant Patients

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Using the results from a computerized mathematical model, Johns Hopkins researchers investigated whether they could improve heart and lung transplantation procedures by transferring patients from low-volume to high-volume transplant centers.
13-Sep-2016 9:00 AM EDT Add to Favorites

New Studies Double Number of Known Sites in Genome Linked to High Blood Pressure

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Several large international groups of researchers report data that more than doubles the number of sites in the human genome tied to blood pressure regulation. One of the studies, by Johns Hopkins University scientists in collaboration with many...
12-Sep-2016 12:15 PM EDT Add to Favorites

Sugar Transforms a Traditional Chinese Medicine Into a Cruise Missile

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More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant. A brief review of published research revealed that the...
7-Sep-2016 8:30 AM EDT Add to Favorites

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