Towards more effective treatments for immunocompromised patients
Institut PasteurFor severely immunocompromised patients, a bone marrow transplant restores immune defenses and allows them to resume normal life.
For severely immunocompromised patients, a bone marrow transplant restores immune defenses and allows them to resume normal life.
While 2021 proved to be a record-breaking year for organ donation in the U.S., many people are still hesitant to register to become a donor. Nationwide, only about 48% of people are registered to be organ donors, according to LifeSource. That's despite surveys showing that 95% of people in the U.S. support organ donation.
A study published in the Journal of the American Medical Association Surgery is the first in North America to demonstrate that living-donor liver transplant is a viable option for patients who have systemically controlled colorectal cancer and liver tumors that cannot be surgically removed.
In a new study from Vanderbilt University Medical Center, 10-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.
For the first time at Northwestern Medicine, surgeons have successfully performed a double-lung transplant on a patient with terminal lung cancer. The patient, 54-year-old Albert Khoury of Chicago, is a non-smoker who was diagnosed with lung cancer at the start of the COVID-19 pandemic. Six months after his transplant, Khoury’s new lungs are working well, and he currently has no signs of cancer left in his body, giving hope to other patients with advanced stages of this deadly disease.
UC San Diego Health is now administering Evusheld to eligible, immunocompromised patients to protect against the COVID-19 virus.
A research team led by Chao Zhou at the McKelvey School of Engineering has used a safe, noninvasive imaging technique to observe the development of a human heart organoid over 30 days.
The Donor Care Network has designated Loyola University Medical Center as a Center of Excellence. The Donor Care Network helps ensure living kidney donors are treated with the utmost courtesy and respect by implementing best practices and recognizing facilities that adhere to their guiding principles. The designation will help Loyola improve patient access to living kidney donor transplants through the National Kidney Registry.
A small black lump, about an inch or so in width, rests on the bottom of a sealed plastic container. It doesn’t look like much – in fact, it doesn’t look like anything. But this little black lump has untold potential, full of secrets for the researchers at Kentucky Research Alliance for Lung Disease (K-RALD) to discover about the pandemic that has ravaged the world for more than two years.
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The University of Maryland School of Medicine’s Institute of Human Virology researchers played a collaborative role in last month’s successful transplant of a genetically-modified pig heart into a patient with terminal heart disease by creating pathogen surveillance strategies and developing an infection prevention strategy for this unprecedent significant medical advancement.
A team of Harrisburg University professors and students have set out to develop a smart disaster prediction and prevention system that could help save thousands of lives across the U.S. each year. Using sets of existing disaster data and an adaptive artificial intelligence model, the team plans to design an alert system capable of predicting natural and human-induced disasters, starting with wildfires and vehicle collisions.
African Americans have an increased risk of kidney failure, and new research shows that some of this risk is related to variations in a gene called apolipoprotein L1 (APOL1). Scientists will address racial disparities in kidney transplant outcomes.
A Mayo Clinic é pioneira e está refinando procedimentos regenerativos que são uma ponte para o transplante. Estes procedimentos estão proporcionando novas opções para fortalecer e reconstruir a saúde enquanto os pacientes aguardam o presente da vida.
妙佑医疗国际(Mayo Clinic) 致力于开发和完善各种再生医疗程序,以帮助患者为器官移植做好准备。这些再生医疗程序为器官移植患者提供了新的选项,让他们能够在等待生命的馈赠期间积极增强体质并恢复健康。
Mayo Clinic no solamente va a la vanguardia de los procedimientos regenerativos que sirven como puente al trasplante, sino que también los refina. Estos procedimientos brindan nuevas alternativas para recuperar y fortalecer la salud, mientras los pacientes esperan que llegue ese regalo de vida.
UCLA researchers presented today the first case of a U.S. woman living with HIV-1 that is in remission after she received a new combination of specialized stem cell transplants for treatment of acute myeloid leukemia (AML). The oral abstract was presented at CROI 2022, the Conference on Retroviruses and Opportunistic Infections.
Mayo Clinic researchers have developed a new scoring system to help health care professionals predict the 30-day mortality risk for patients with alcohol-associated hepatitis, and the tool appears to more accurately identify patients at highest risk of death and those likely to survive.
New Jersey Woman Gives the Gift of Life to Her Spouse this Valentine's Day
The Johns Hopkins Health System will no longer use a long-standing clinical standard that factors a patient’s race into kidney function tests.
Mayo Clinic and Carnegie Mellon University (CMU) announced today a research agreement to transform organ transplantation. The institutions will bioengineer innovative approaches to address barriers in organ transplantation.
While balancing the demands of the COVID-19 pandemic, the team at Baylor Scott & White Medical Center – Temple was able to successfully help nearly 200 patients receive a life-changing organ transplant last year. From January through December 2021, 191 abdominal transplant procedures were conducted, a new record for the hospital and a 25% increase from its previous record set in 2017.
Diagnosed with acute liver failure and her health rapidly deteriorating, it seemed like 11-month-old Lennon would need a miracle to survive. Thanks to a team of specialists at Children’s Hospital Los Angeles, she just celebrated her third birthday.
For many COVID-19 patients with irrecoverable lung damage, transplantation is the only option for survival. However, there is limited information about the long-term outcomes of these patients, including postoperative complications, hospital length of stay and survival. A new study published in the Journal of the American Medical Association (JAMA) shows positive outcomes in the first 30 consecutive COVID-19 patients who underwent a lung transplant at Northwestern Medicine in Chicago.
Un estudio de Mayo Clinic recientemente publicado afirma que el mayor riesgo para los receptores de un trasplante renal no es el rechazo del órgano, sino el cáncer, las infecciones y las enfermedades cardíacas.
Amid the uncertainty of the ongoing COVID-19 pandemic, the Cedars-Sinai Comprehensive Transplant Center and Smidt Heart Institute together completed 573 solid organ transplants in 2021, surpassing 2020’s count of 529 and achieving a new record for the medical center.
câncer, infecções e doença cardíaca representam os maiores riscos para as pessoas que recebem um transplante de rim, e não a rejeição do órgão, de acordo com um estudo da Mayo Clinic publicado recentemente.
مدينة روتشستر، ولاية مينيسوتا- يشكل السرطان والعَدوى وأمراض القلب الخطر الأكبر على متلقي زراعة الكلى- وليس رفض الأعضاء - وفقًا لدراسة مايو كلينك المنشورة مؤخرًا، حيث اكتشف الباحثون أن وفاة المتلقي إثر عوامل أخرى غير رفض العضو هي السبب الرئيسي لفقدان الكلى المزروعة. فواحدة فقط من كل 4 حالات لفقدان الكلى المزروعة تكون بسبب رفض العضو.
根据最近发表的一项妙佑医疗国际(Mayo Clinic)研究,对肾移植受者危害最大的是癌症、感染和心脏病,而不是器官排斥。研究人员发现,由于器官排斥以外的因素导致的受者死亡是移植肾丢失的主要原因。只有1/4的移植肾丢失是由器官排斥造成的。
Cardiothoracic surgeons in the Smidt Heart Institute at Cedars-Sinai recently performed a groundbreaking robotic-assisted lung transplant.
Throughout the month of February—American Heart Month—the Cedars-Sinai Newsroom will highlight new research, heart-health recommendations and clinical and surgical advances. Experts from the Smidt Heart Institute at Cedars-Sinai, home to California’s top heart and heart surgery programs, are available to address these timely heart-related topics.
A Smidt Heart Institute analysis of lung transplantations performed nationally shows significant help for patients with severe, irreversible lung damage from COVID-19.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current clinical advances include combination therapies for thyroid cancer and multiple myeloma, as well as discoveries to improve CRISPR/Cas9 gene editing, to identify biomarkers for immunotherapy response, to utilize T cell therapy for osteosarcoma and to understand of the role of LIP-1 in regulating ERK signaling.
A record-high 346 organ transplants were done at the University of Chicago Medicine in 2021 — up 42% from the previous year and part of a nationwide trend in transplant surgeries.
For the first time, University of Utah Health scientists have shown that artificial intelligence could lead to better ways to predict the onset and course of cardiovascular disease.
Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant. Their new study in the Journal of Immunology shows that a partial bone marrow transplant helps these mice by introducing a population of healthy immune cells called monocytes.
Cancer, infections and heart disease pose the greatest risk to kidney transplant recipients ― not organ rejection ― according to a recently published Mayo Clinic study. Researchers discovered that recipient death due to factors other than organ rejection is the leading cause for transplanted kidney loss. Only 1 in 4 transplanted kidney losses were caused by organ rejection.
The Cedars-Sinai Cancer Blood & Marrow Transplant Program’s one-year patient survival rate exceeded expectations compared to transplant centers in the U.S. whose similar patients underwent allogeneic transplants, according to a national report that tracks those outcomes.
A critical shortage of blood, which has stretched supplies thin nationwide, threatens hospitals' ability to provide many types of patient care. The Red Cross has just declared the first-ever national blood crisis. A blood bank director with nearly 40 years of experience urges every eligible person to step up and make an appointment to donate as soon as possible.
Loyola Medicine experts have concluded that COVID-19 vaccine requirements for lung transplant patients are an ethical and necessary practice. Daniel Dilling, MD, medical director of the lung transplantation program at Loyola Medicine, and Mark Kuczewski, PhD, a professor of medical ethics at the Stritch School of Medicine, shared their recommendation in a paper published by the Journal of Heart and Lung Transplant.
A new analysis of national kidney transplant and organ discard data concludes that too many deceased donor organs with acute kidney injury (AKI) may be needlessly going to waste because of a change in the way kidneys are evaluated.
In the future, mass transportation will almost certainly involve self-driving vehicles. The aerospace industry is pushing that idea even further, all the way to space. Now, a Cornell University project that demonstrates the technology’s potential is poised to take flight.
In a first-of-its-kind surgery, a 57-year-old patient with terminal heart disease received a successful transplant of a genetically-modified pig heart and is still doing well three days later. It was the only currently available option for the patient.
New NCCN Guidelines for Patients: Graft-Versus-Host Disease offers clarity and consensus on how best to address and treat a common and complex immune response side-effect from stem cell transplants.
With an $8 million grant from the National Institutes of Health (NIH), the next stage of the THINKER project — called THINKER-NEXT — will aim to provide a comprehensive view of the risks and benefits of transplanting HCV-infected kidneys into non-infected patients.
This year the medical and research advancements from the Icahn School of Medicine at Mount Sinai and the Mount Sinai Health System ranged from COVID-19, to PTSD, to the first ever successful trachea transplant surgery. Our doctors and researchers were not only at the forefront of the pandemic providing expertise and new studies surrounding the virus, its symptoms and effects, but also excelling in revolutionary surgeries and progressive research to continue showcasing Mount Sinai as a top medical institution and medical school in the country. Here are some of Mount Sinai’s breakthrough stories of the year: