Researchers have made huge strides in ensuring that red blood cell substitutes – or artificial blood – are able to work safely and effectively when transfused into the bloodstream.
A new CALM mutation causes lethal arrhythmia in humans. Using cardiomyocytes -- or heart muscle cells -- from human iPS cell and recombinant calmodulin proteins, the group studied catecholaminergic polymorphic ventricular tachycardia -- or CPVT, a rare and life-threatening genetic condition. The team was able to reproduce severe arrhythmia in patient-derived iPS cell models of exercise-induced CPVT with calmodulin mutations.
New UCLA research suggests that a novel machine-learning technique known as "causal forest" was about five times more efficient than the current clinical practice of treating patients with high blood pressure.
Reducing caloric intake from added sugars is a Leading Health Indicator in Healthy People 2030, a national public health initiative led by the US Department of Health and Human Services that sets data-driven national objectives to improve health and wellbeing over the next decade.
UC San Francisco interventional cardiologists and interventional echocardiographers recently performed two novel minimally invasive cardiac procedures for the first time in the health system.
In adolescents, sedentary time may increase heart size three times more than moderate-to-vigorous physical activity, a paper published in the Scandinavian Journal of Medicine & Science in Sports concludes.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. This special edition features presentations by MD Anderson researchers at the American Association for Cancer Research (AACR) Annual Meeting 2023.
Among Indigenous, rural non-industrial populations inhabiting the tropical forests of lowland Bolivia, researchers report, there appears to be an optimal balance between levels of food consumption and exercise that maximizes healthy brain aging and reduces the risk of disease.
Wireless or leadless pacemakers, commonly implanted in adults, may be a safe and effective short-term option for children with slow heartbeats, according to new research published today in Circulation: Arrhythmia and Electrophysiology, a peer-reviewed journal of the American Heart Association.
A first-of-its-kind study has established pediatric reference intervals for two common tests for cardiovascular disease. Published in AACC’s The Journal of Applied Laboratory Medicine, these findings are crucial to advancing diagnosis and treatment of heart conditions in children.
New research from the UC Davis School of Medicine shows high blood pressure in early adulthood is associated with worse brain health in late life — especially for men. The results suggest that treating hypertension in young and middle-aged adults may help prevent dementia and Alzheimer’s disease.
Two Smidt Heart Institute experts have been honored for their contributions to medical research by being inducted into select medical societies, while a third expert has been selected for a leadership position.
Patients with obstructive sleep apnea (OSA) often show cognitive deficits, but these have traditionally been attributed to co-morbidities such as as systemic hypertension, cardiovascular and metabolic diseases, and type 2 diabetes.
People who have sleep problems may be more likely to have a stroke, according to a study published in the April 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. Sleep problems included getting too much or too little sleep, taking long naps, having poor quality sleep, snoring, snorting and sleep apnea. In addition, those who had five or more of these symptoms had an even greater risk of stroke. The study does not show that sleeping problems cause stroke. It only shows an association.
All too often, people waiting for lifesaving organ transplants cannot get them. One of the biggest challenges is the lack of viable donated organs. Promising medical advances are opening the doors to more transplants and saving more lives, says Mauricio Villavicencio, M.D., surgical director of heart and lung transplantation at Mayo Clinic in Rochester.
More than 100,000 people in the U.S. are awaiting new organs. Many won’t live long enough to get them. The new chief of transplant at Penn State Health Milton S. Hershey Medical Center debunks the myths that get between donors and recipients.
Complications after a minimally invasive balloon pulmonary angioplasty have decreased substantially over the last decade for patients with high blood pressure in their pulmonary arteries caused by chronic blood clots, known as CTEPH. The procedure, which is offered for patients who are not candidates for surgery, involves inflating a balloon inside of diseased lung arteries to break up clots and restore blood flow to the lungs.
Hackensack University Medical Center is the only site in New Jersey that is participating in the ROADSTER 3 clinical trial to assess real-world outcomes for patients with carotid artery disease who have an average surgical risk and undergo a minimally invasive surgical procedure called transcarotid artery revascularization (TCAR).
Surviving family members of a person who died from sudden cardiac death rely on information from death investigators and health care professionals to process their relative’s death and understand their own risk of inherited heart conditions.
Chronic kidney disease is a strong cardiovascular risk factor and is often accompanied by hypertension and diabetes. A new risk model for cardiovascular disease, developed by Penn, was found to be more accurate than existing clinical models.
According to some estimates, up to 80% of patients who experience a ruptured abdominal aortic aneurysm will die before they reach the hospital or during surgery. But early intervention can prevent rupture and improve outcomes. In Physics of Fluids, researchers make a computational model of the cardiovascular system in order to predict early AAA rupture and monitor patients’ blood vessel conditions. They mimicked specific health conditions and investigated various hemodynamic parameters using image-based computational blood dynamics.
The peer-reviewed study, published in The European Heart Journal – Digital Health, looked at data from 83,000 people who had undergone a 15-second electrocardiogram (ECG) comparable to the kind carried out using smart watches and phone devices.
Multiple studies have demonstrated that Black patients are significantly less likely than white patients to undergo invasive cardiovascular procedures. Prior research also has demonstrated substantial racial disparities in the use of implantable cardioverter-defibrillators (ICDs) that can be lifesaving for those at high risk for sudden cardiac death.
A heartbeat is a carefully coordinated series of electrical signals led by sodium ion channels, which tell the heart when to contract and to relax. Any disruption to these signals may lead to cardiac diseases such as an irregular heartbeat, or arrhythmia. Two researchers at Washington University in St. Louis have taken a closer look at this process at the molecular level and have found what may provide new insights into different heart conditions and how to develop better therapies.
Mediterranean and low fat dietary programmes reduce the likelihood of death and heart attack in patients at heightened risk of cardiovascular disease, finds the first comparative review based on randomised trials of seven popular dietary programmes published by The BMJ today.
Sleeping too little or too long is linked with a shorter life, but scientists have found that physical activity counteracts some of these negative effects.
High blood pressure in children is not uncommon, and research shows it may lead to high blood pressure in adulthood, as well as problems with the heart, blood vessels and kidneys.
The TCT 2023 Career Achievement Award will be presented to Stuart J. Pocock, PhD, during Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT will take place October 23-26, 2023, in San Francisco at the Moscone Center. The award is given each year to an outstanding individual who has made significant contributions to the field of interventional cardiology and transformed patient care through their career endeavors, research pursuits, and mentorship.
A study, co-led by University Hospitals Harrington Heart & Vascular Institute, could lead to the first FDA approval of a therapy giving thousands of patients hope for an alternative to amputation.
Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.
A new study published today in the Journal of Molecular and Cellular Cardiology Plus by Timothy A. McCaffrey, professor of medicine at the George Washington University School of Medicine & Health Sciences and INOVA Fairfax Hospitals demonstrates how RNA biomarkers may be used to confirm heart disease. The study, which involves the largest analysis of blood RNA from patients with angiographically confirmed CAD, adds several novel dimensions to the current understanding of heart disease and could one day lead to a simple blood test that would help doctors diagnose heart disease in the physician’s office.
Weight loss was associated with decreased risk factors for cardiovascular disease and Type 2 diabetes for at least five years — even if some weight was regained, according to a review of research on behavioral weight loss programs.
Estar acima do peso afeta saúde mais do que você imagina. Um novo artigo de revisão para a revista médica Journal of the American College of Cardiology da Mayo Clinic descreve como a obesidade afeta os exames comuns usados para diagnosticar doenças cardíacas e afeta os tratamentos.
Tener sobrepeso afecta salud cardíaca de más formas que las que podría imaginar. Un nuevo artículo de revisión de la Revista del Colegio Americano de Cardiología de Mayo Clinic describe cómo la obesidad afecta las pruebas comunes que se usan para diagnosticar la enfermedad cardíaca e impacta en los tratamientos.
يؤثر الوزن الزائد على صحة قلبك من نواحٍ قد لا تخطر على بالك. توضح ورقة المراجعة المنشورة في مجلة الكلية الأمريكية لأمراض القلب من مايو كلينك كيف تؤثر السُمنة في الاختبارات الشائعة المُستخدمة في تشخيص مرض القلب وتأثيرها على العلاجات.