Curated News: Grant Funded News

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A University of California, Irvine-led team of researchers have discovered that the oldest-old, those who live to be 90+ and have superior cognitive skills, have similar levels of brain pathology as Alzheimer’s patients, however, they also have less brain pathology of other neurodegenerative diseases that cause memory and thinking problems.

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A $2.5 million initiative supported by philanthropists Irwin and Joan Jacobs has created the Stuart and Barbara L. Brody Endowed Chair in Circadian Biology and Medicine, along with a supporting research fund, to target largely unexplored areas related to circadian biology and patient health.

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Researchers from Rensselaer Polytechnic Institute (RPI) and Albany Medical College were awarded a $3.3 million grant over five years by the National Cancer Institute to use artificial intelligence (AI) to improve targeted drug therapy in HER2-positive breast cancer treatment. HER2-positive breast cancer tends to grow and spread quickly, but targeted treatments improve outcomes.

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From advancing artificial intelligence to strengthening our national security, the 2023 Hertz Fellows will address the most pressing challenges facing our nation.

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Mental health is a significant issue across the country. In 2021, over 57 million adults in the United States – about 1 in 5 – experienced mental illness, according to the National Alliance on Mental Illness. As of February 2023, 36.8% of adults in Texas reported symptoms of anxiety and/or depressive disorder, compared to 32.3% of adults in the U.S., according to a Kaiser Family Foundation analysis of U.S. Census Bureau data.

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Acoustic signals can be effectively used for monitoring glacial runoff and provide a cheaper and more accessible alternative to existing methods.

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The grounds of the University of Northern Colorado received a welcome living, breathing facelift last week. As part of Arbor Day and Earth Day celebrations this year, students, faculty and staff picked up shovels and got their hands dirty planting 122 new trees across the university’s 250-acre campus.

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Scientists at Wake Forest University School of Medicine have uncovered a novel mechanism that shows increased sugar intake and elevations in blood glucose are sufficient to cause amyloid plaque buildup in the brain, which increases the risk of Alzheimer’s disease.

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The University of Arkansas at Little Rock has received a $3.5 million grant from the Windgate Foundation to endow the directorship of its School of Education. This gift will support the transformation of teacher education at UA Little Rock in its quest to become a premier provider of teachers in the state.

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A UC Davis MIND Institute analysis of 13 studies finds that a common autism screening tool is useful, but a clinician’s judgment is still needed.

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Georgia Tech researchers have been selected by NASA to lead a $7.5 million center that will study the lunar environment, and explore the generation and properties of volatiles and dust.

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The Uniformed Services University (USU) has been awarded a $404,703 grant to implement a WIC Community Innovation and Outreach Project (WIC CIAO), designed to increase WIC enrollment in active duty military families.

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Tissue engineering research has shown that a skin cell type could be a new therapeutic target to accelerate the healing of burns and possibly other wounds.

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Researchers from Rice University have created drug-filled microparticles that can be engineered to degrade and release their therapeutic cargo days or weeks after administration. By combining multiple microparticles with different degradation times into a single injection, the researchers could develop a drug formulation that delivers many doses over time.

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The SUNY College of Environmental Science and Forestry (ESF) is pleased to announce Upstate 2.0, a partnership between ESF and Cornell University that aims to bolster economic development in upstate New York, has received a $1 million development award from the National Science Foundation’s Regional Innovation Engines.

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Surviving a stroke can bring many long-term effects – including a much higher risk of dementia. But a study suggests that blood sugar may play a key role in that risk.

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A team from the University of Illinois has quantified the plant cell properties in two C4 species, including cell shape, chloroplast size, and distribution of cell-to-cell connections called plasmodesmata, providing information that can change how people model photosynthesis thanks to their 3D reconstructions.

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Improving the diagnostic process and preventing errors are the focus of two studies funded by the U.S. Department of Health and Human Services (HHS) and led by Eric Thomas, MD, associate dean for health care quality with McGovern Medical School at UTHealth Houston.

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Impairments in the lymphatic system may contribute to brain diseases, such as neurodegenerative diseases and stroke. Researchers have found a noninvasive and nonpharmaceutical method to influence glymphatic transport using focused ultrasound, opening the opportunity to use the method to further study brain diseases and brain function.

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Iowa State University engineers are developing advanced tools for cell manufacturing that could improve the cost and availability of therapeutic cells capable of fighting diseases such as cancers, heart disease, lupus and other autoimmune diseases.

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The University of Texas MD Anderson Cancer Center was awarded more than $5.7 million in grants from Break Through Cancer to support collaborative research teams working to discover novel molecular targets to eradicate minimal residual disease in acute myeloid leukemia (AML) and to treat clonal hematopoiesis, a precursor to AML.

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A groundbreaking data science effort to better understand and harness the power of stories has earned the University of Vermont a $20 million research capacity building award from the National Science Foundation (NSF) through its Established Program to Stimulate Competitive Research (EPSCoR).

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Corticospinal activity is temporally coded with precise prehension movements in mice. Disrupting this patterned activity impairs movements, highlighting the critical role of corticospinal network modulation in the execution of precision movements.

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Rutgers is part of a new federally funded regional collaboration to drive economic and technological advancements in photonics, the National Science Foundation (NSF) announced. The consortium, which includes researchers from Rutgers-Newark and Rutgers-New Brunswick, awarded a development grant from the NSF’s Regional Innovation Economic Engine consortium, led by Princeton University and co-led by Rowan University, with partners throughout New Jersey and neighboring states Delaware, Pennsylvania and New York.

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At TTUHSC El Paso, addressing health disparities remains at the forefront of our mission.

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The University of Kentucky, as lead organization, together with partners across Kentucky and Tennessee, has been awarded $1 million from the U.S. National Science Foundation’s Regional Innovation Engines, or NSF Engines, program. This team’s proposal, “Advancing carbon centric circular economy technologies for advanced manufacturing solutions (KY, TN),” is led by a coalition named Generate Advanced Manufacturing Excellence for Change (GAME Change).

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How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, thanks to a combination of field and lab studies, an international research team has shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.

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Van Andel Institute’s Hui Shen, Ph.D., and Washington University School of Medicine in St. Louis’s Ting Wang, Ph.D., will co-lead a collaborative project supported by the Somatic Mosaicism across Human Tissues (SMaHT) Network, a new $140 million National Institutes of Health-led effort to better understand the genetic differences between individual cells and tissues in the body.

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A regional collaboration led by Case Western Reserve University has won a $1 million grant from the National Science Foundation (NSF) --the only award in Ohio--to plan economic, environmental and manufacturing growth across the 18-county Northeast Ohio region.

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SpaceMarkers, a new machine learning software developed by researchers at the Johns Hopkins Convergence Institute and the Johns Hopkins Kimmel Cancer Center, can identify molecular interactions among distinct types of cells in and around a tumor.

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There are more than 80,000 sheep and lambs living on over 2,000 farms in New York State. Their wool has many uses including clothing, carpets, furniture, bedding, insulators, fertilizers, and more. However, about 10-15% of wool is wasted during the sorting and cleaning processes. Researchers from Rensselaer Polytechnic Institute are aiming to turn that waste into a new profit source for farmers, and produce an eco-conscious, high-performance yarn in the process.

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A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research published in The New England Journal of Medicine and led by an oncologist from Dana-Farber Cancer Institute.

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Over 3,000 generations of laboratory evolution, Georgia Tech researchers watched as their model organism, “snowflake yeast,” began to adapt as multicellular individuals. In new research, the team shows how snowflake yeast evolved to be physically stronger and more than 20,000 times larger than their ancestor. Their study is the first major report on the ongoing Multicellularity Long-Term Evolution Experiment (MuLTEE), which the team hopes to run for decades.

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UNC Charlotte’s Cato College of Education, a leader in literacy instruction and research, has been selected by the Mebane Foundation to help continue its legacy of supporting innovation in literacy education in North Carolina and beyond through a five-year grant and potential endowment of up to $23 million.

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In an effort to determine the cause behind a rare condition that causes heart failure in children, University of Maryland School of Medicine researchers have identified new gene mutations responsible for the disorder in an infant patient. They were then able to learn how the mutation works and used a drug to reverse its effects in heart muscle cells derived from stem cells from the patient.

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Rutgers Institute for Health researcher, Dr. Ashley Grosso, receives grant from NIH to conduct study on barriers to HIV research in Africa.

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The National Science Foundation's program to build research capacity across the country has awarded a $20 million grant to support Iowa researchers working to make the state a leader in advanced biomanufacturing. The researchers will use microbes to produce plastics for 3D printing, fibers for flexible and rigid materials and proteins for medical diagnostics and therapeutics.

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Solar flares and coronal mass ejections (CME) are two of the most energetic processes in the solar system, showering the Earth’s magnetic field with billions of tons of highly energetic plasma gas, potentially disrupting power grids, satellites and communications networks.

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IThe Beall Center for Art + Technology at the University of California, Irvine has received a $200,000 exhibition grant from the Getty Foundation to present “Future Tense: Art, Complexity and Predictability,” a thematic show and artist residency program. The Beall Center is among more than 45 Southern California awardees participating in the third collaboration of Getty’s Pacific Standard Time initiative.

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Repeated mammograms contain data on changes in breast density over time that could help identify women at high risk of breast cancer and even reveal which breast is likely to be affected, according to a study by researchers at Washington University School of Medicine in St. Louis.

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A new study led by a Johns Hopkins Bloomberg School of Public Health researcher found that the percent of patients treated for opioid use disorder with methadone significantly decreased their use of fentanyl during a year of treatment. The percent who tested positive for fentanyl declined on average from 21.8 percent in week one to 17.1 percent in week 52.

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Findings reveal a previously unknown way in which the brain and immune system talk to each other and may identify a new therapeutic target for MS and other brain disorders.

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Sian Piret, PhD, in the Renaissance School of Medicine at Stony Brook University, has received a $1.4 million grant from the National Institute of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to investigate a certain metabolic process called BCAA catabolism that is known to occur with acute kidney injury, but its exact role remains unknown.

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The center will focus on “Preserving the Environment,” to support the U.S. DOT’s climate solution and sustainability goals. The center will promote transit access, multimodal infrastructure, compact and efficient land use patterns, as well as resilience and climate mitigation and adaptation.