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A study published April 11 in the Journal of the American Medical Association (JAMA) evaluated two drugs that act on the renin-angiotensin system (RAS) as potential treatments for severe COVID-19. Severe acute respiratory syndrome coronavirus2 (SARS-CoV-2), the virus that causes COVID-19, enters pulmonary and myocardial cells through binding of its spike protein to the human angiotensin-converting enzyme 2 (ACE2). ACE2 is a vital enzyme that controls blood pressure and blood flow to multiple organs, including the lungs, heart and kidneys.

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Now that we’ve arguably rounded the corner from the pandemic, researchers are dissecting our response and how we can improve it in the future.Sebastian Souyris, assistant professor and Dean R. Wellington ’83 (Junior) Chair at Rensselaer Polytechnic Institute’s Lally School of Management, contributed to research led by Anton Ivanov, assistant professor in the Gies College of Business at the University of Illinois Urbana-Champaign.

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South Carolina residents were more hesitant than Americans as a whole to receive the COVID-19 vaccine during the fall of 2020, report researchers in the Department of Psychiatry and Behavioral Sciences at the Medical University of South Carolina (MUSC) in the Journal of Psychiatry Research.

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After helping to develop and test new mRNA technologies for COVID-19 vaccines, University of Maryland School of Medicine (UMSOM) researchers and scientists are turning their attention to utilizing this innovative technology to ward off other infectious diseases like malaria and influenza.

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The human body is capable of creating a vast, diverse repertoire of antibodies—the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.

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A group of physicians and scientists with the University of Miami Miller School of Medicine are releasing an important study that will be published in the journal Pediatrics on Thursday, showing that COVID-19 can cross into the placenta of pregnant women and cause brain injury in newborns, as evidenced with 2 cases they treated here in Miami. One of the infants also died at about 13 months old. Further testing of the infant’s brain specimen showed that the virus was still present in the brain at the time of death—which was over a year after birth.

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Researchers have shown that, in two cases, COVID-19 infection breached the placenta and caused brain damage in the newborn.

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Cleveland Clinic researchers found 41% of patients with long COVID, had moderate to severe sleep disturbances. The retrospective analysis also identified risk factors for moderate to severe sleep disturbances, including race, hospitalization for COVID-19, greater anxiety severity and fatigue. After adjusting for demographics, Black patients were three times more likely to develop these sleep disturbances. The findings were published in Journal of General Internal Medicine.

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Teens’ trust in the news they consume on social media – or lack of it – may be key to whether it supports or detracts from their well-being, according to Cornell-led psychology research.

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Recent study reveals neurodegenerative biomarkers after COVID-19, gives clues for monitoring and potential treatment of long COVID

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The COVID-19 pandemic has been accompanied by an unprecedented global infodemic that has led to confusion about the benefits of medical and public health interventions, with substantial impact on risk-taking and health-seeking behaviors, eroding trust in health authorities and compromising the effectiveness of public health responses and policies.

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A study by researchers at Washington University School of Medicine in St. Louis shows that vaccinating people with updated boosters as new variants of the virus that cause COVID-19 emerge could shore up population immunity even as the virus mutates, and thereby prevent another deadly COVID-19 wave.

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New research from the University at Buffalo provides the most comprehensive assessment to date of drinking patterns during the COVID-19 pandemic and their association with four clinically prevalent mental health disorders in the U.S.

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In a study among residents of Ventura County, California, rates of sudden cardiac arrest rose sharply during the COVID-19 pandemic.

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In a new study, researchers analyzed data from Cali, Colombia, to develop a model that provides a template for tracking data, predicting transmission, and informing health surveillance systems.

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The COVID-19 pandemic posed an immense challenge on the health care industry in 2020 and 2021. While hospitals were inundated with COVID-19 cases, other illnesses such as respiratory syncytial virus (RSV) saw a decrease in hospital visits, particularly in the fourth quarter of 2020 and the first quarter of 2021.

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From septic shock to sticker shock. Keep up with this ever-growing, changing sector. Below are some of the latest stories on healthcare on Newswise.

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Researchers have designed a molecule that slows the effects of one of SARS-CoV-2's more dangerous components – an enzyme called a protease that cuts off the immune system's communications and helps the virus replicate. While much more needs to happen to develop a drug, scientists can begin to imagine what that drug could look like – thanks to new images of the molecule bound to the protease.

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A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

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Scientists report using a single-atom-thick nanomaterial to build a device that can simultaneously detect the presence of the viruses that cause COVID-19 and the flu — at much lower levels and much more quickly than conventional tests for either. They will present their results at ACS Spring 2023.

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Researchers examined how a country’s number of published 3D protein structures for coronaviruses correlated with its economic output and population. The findings reveal important insights into how different countries' research establishments respond to disease outbreaks.

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People infected with SARS-CoV-2, the virus that causes COVID-19, may experience genome structure changes that not only may explain our immunological symptoms after infection, but also potentially link to long COVID, according to a new study by researchers at UTHealth Houston.

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Nearly a third of Americans (29%) say COVID-19 made them more worried than ever about having obesity prompting about 28 million people to consider weight-loss methods they hadn’t thought about before the pandemic began, including nearly 6.4 million thought about turning to either weight-loss surgery or taking prescription anti-obesity drugs for the first time, according to a new survey whose findings were published online in the peer-reviewed journal, Surgery for Obesity and Related Diseases (SOARD).

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UC San Diego researchers describe why SARS-CoV-2 subvariants spread more rapidly than the original virus strain, and how an early treatment might have made people more susceptible to future infections.

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Post-acute sequelae SARS-CoV-2 infection (PASC), also known as long-haul COVID-19, is positively associated with posttraumatic stress disorder (PTSD), says new research presented at Physiatry ’23, the Association of Academic Physiatrists (AAP) annual meeting.

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A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2. It proved as effective as vaccines administered by injection or intranasally in the research. If ultimately approved for human use, it could be a weapon against all COVID-19 variants and boost uptake, particularly in low- and middle-income countries, and among those with an aversion to needles.

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Early COVID-19 pandemic suspicions about dogs’ resistance to the disease have given way to a long-haul clinical data gap as new variants of the virus have emerged.