Curated News: JAMA

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Released: 26-Oct-2021 4:35 PM EDT
Study supports safety of COVID-19 vaccines in people with a history of severe allergic reactions
Massachusetts General Hospital

New research addresses ongoing concerns regarding risks of allergic reactions after receiving mRNA COVID-19 vaccines, particularly for individuals with a history of severe allergic reactions.

26-Oct-2021 9:40 AM EDT
Transplants for alcohol-related liver inflammation surge during pandemic
Michigan Medicine - University of Michigan

Registrations for the national organ transplant waiting list related to alcoholic hepatitis as well as the number of deceased donor liver transplants for the inflammatory liver condition rose significantly during the pandemic, Michigan Medicine researchers found.

22-Oct-2021 5:05 PM EDT
Change in Waiting List Registration, Liver Transplant for Alcoholic Hepatitis During COVID-19
JAMA - Journal of the American Medical Association

Researchers report waiting list registrations and deceased donor liver transplants in the U.S. for alcoholic hepatitis, which can develop after a short period of alcohol misuse, increased during COVID-19, exceeding volumes forecasted by pre-COVID-19 trends, while trends for alcohol-related cirrhosis and non-alcohol-associated liver disease remained unchanged.

Released: 25-Oct-2021 11:50 AM EDT
March Madness: Researcher sees temporary increase in COVID-19 cases in counties where universities played in NCAA Tournament   
Beth Israel Lahey Health

A new analysis by a researcher at Beth Israel Deaconess Medical Center (BIDMC) finds a link between large gatherings of unvaccinated county residents – both students and non-students – and an increase in COVID-19 infections in the university’s community.

Newswise: Targeted drug shows activity against brain metastases in kidney cancer
20-Oct-2021 4:05 PM EDT
Targeted drug shows activity against brain metastases in kidney cancer
Dana-Farber Cancer Institute

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

Released: 20-Oct-2021 12:00 PM EDT
MD Anderson Research Highlights for October 20, 2021
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include new targeted therapy approaches for chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML), predicting survival following follicular lymphoma treatment, understanding how AML responds to checkpoint blockade therapy, identifying disparities in colorectal cancer screening, pregnancy outcomes following surgery for early-stage cervical cancer, and the discovery of a novel SHP2 targeted therapy.

Released: 19-Oct-2021 11:40 AM EDT
UC San Diego Study: E-cigarettes Don’t Help Smokers Stay Off Cigarettes
University of California San Diego

E-cigarette use did not help smokers quit and may make smokers more likely to relapse, according to a study by Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego and Moores Cancer Center.

19-Oct-2021 10:00 AM EDT
Yelp Star Ratings on Health Care Facilities May Reveal County-Level Death Rate Disparities
Perelman School of Medicine at the University of Pennsylvania

By collecting data from Yelp reviews on health care facilities and matching them to location data, Penn research shows how online reviews can provide a window into better care

18-Oct-2021 5:30 PM EDT
People with cancer and cancer survivors in low-income and rural areas face greater risk of suicide
University of Texas Health Science Center at Houston

Cancer is an unwelcome blow for anyone, but those diagnosed with cancer who live in low-income and rural areas face an increased risk of suicide compared with those living in high-income and urban areas, according to a study by The University of Texas Health Science Center at Houston (UTHealth Houston).

14-Oct-2021 5:10 PM EDT
Patients hospitalized for COVID-19 this year could pay thousands of dollars, study suggests
Michigan Medicine - University of Michigan

Americans who get seriously ill from COVID-19 in 2021 might have to pay thousands of dollars in bills from their hospitals, doctors and ambulance companies, a new study suggests. Most health insurance companies voluntarily waived co-pays, deductibles and other cost-sharing for hospitalized COVID-19 patients in 2020, but many major insurers lifted those waivers in early 2021.

Released: 18-Oct-2021 8:30 AM EDT
Even College Campuses with 100 Percent Vaccine Rates Need COVID-19 Tests
Florida Atlantic University

An analytical study examined levels of vaccine efficacy and mitigation strategies. If 100 percent were vaccinated with 90 percent vaccine efficacy, testing and quarantine did not substantially reduce infections. At 75 percent efficacy, weekly testing substantially reduced the number of infections; at 50 percent, testing and quarantine markedly reduced infections. At 50 to 75 percent efficacy, testing reduced infections up to 93.6 percent. Quarantining for 10 days only modestly reduced infections until vaccine efficacy dropped to 50 percent. Findings suggest that testing and isolating positive cases may remain important mitigation strategies for universities even with 100 percent of students vaccinated.

Released: 14-Oct-2021 12:35 PM EDT
High Ferritin in Severe Covid-19 Pneumonia is Linked to Improved Outcomes After Steroid Treatment
Stony Brook University

Physicians from the Renaissance School of Medicine at Stony Brook University discovered that for patients with severe Covid-19 pneumonia who had higher ferritin in their blood and were treated with a corticosteroid, fewer intubations and deaths resulted. Their findings are reported in JAMA Network Open.

12-Oct-2021 12:55 PM EDT
How many people get ‘long COVID?’ More than half, researchers find
Penn State College of Medicine

More than half of the 236 million people who have been diagnosed with COVID-19 worldwide since December 2019 will experience post-COVID symptoms — more commonly known as “long COVID” — up to six months after recovering, according to Penn State College of Medicine researchers.

Released: 8-Oct-2021 11:45 AM EDT
Study Shows Medicaid Expansion Increased Access to Bariatric Surgery for Obesity
Atrium Health Wake Forest Baptist

Following the Affordable Care Act (ACA) Medicaid expansion, access to bariatric surgery as a treatment for obesity increased by 31% annually for lower-income Medicaid-covered and uninsured white adults age 26 to 64 but not for Hispanic and Black adults, according to research conducted by scientists at Wake Forest School of Medicine.

6-Oct-2021 2:00 PM EDT
Children’s Hospital of Philadelphia-led Study Finds that Biggest Share of U.S. Obstetric Hospitals Deliver Fewer than 500 Babies Per Year
Children's Hospital of Philadelphia

A research team led by Children’s Hospital of Philadelphia (CHOP) has analyzed the birth volume and geographic distribution of obstetric hospitals across the United States and found that a plurality of those hospitals delivers fewer than 500 infants per year. The researchers also found that nearly a fifth of low-volume hospitals are more than 30 miles from another obstetric hospital, and more than half are in rural communities.

Released: 6-Oct-2021 2:10 PM EDT
Cancer costs U.S. more than $156 billion, with drugs a leading expense
Penn State College of Medicine

Care for the 15 most prevalent types of cancer in the U.S. cost approximately $156.2 billion in 2018, according to a team of Penn State College of Medicine researchers.

Released: 5-Oct-2021 2:50 PM EDT
Vaginal birth may be safer for pregnant women with kidney and liver transplants
University of California, Los Angeles (UCLA), Health Sciences

Cesarean birth rates are on the rise, and this is especially true for high-risk pregnant women who have undergone organ transplantation. While cesarean births account for 31% of all deliveries in the United States, the rate of cesarean births for pregnant people with kidney transplants is 62.6% and 44.6% for liver transplants.

Released: 27-Sep-2021 5:20 PM EDT
Passage of recreational cannabis laws leads to some rise in use but not for all demographics
Columbia University, Mailman School of Public Health

The U.S. is seeing an increased use of cannabis resulting from its legalization for recreational purposes, according to a study conducted at Columbia University Mailman School of Public Health.

   
Released: 27-Sep-2021 5:15 PM EDT
New analysis shows use and predictors of low-value care in health systems nationwide
Brigham and Women’s Hospital

Researchers estimate that up to $101 billion in health care spending is wasted each year due to over-treatment or the delivery of “low-value care.”

Newswise: Anti-seizure medication improves cognitive function in some Alzheimer’s patients
Released: 27-Sep-2021 4:05 PM EDT
Anti-seizure medication improves cognitive function in some Alzheimer’s patients
University of California, Los Angeles (UCLA), Health Sciences

An inexpensive anti-seizure medication markedly improves learning and memory and other cognitive functions in Alzheimer’s patients who have epileptic activity in their brains, according to a study published in the Sept. 27th issue of JAMA Neurology.

22-Sep-2021 10:45 AM EDT
Metastatic prostate cancer comes in two forms, which could guide treatment
University of Wisconsin–Madison

Scientists have identified two subtypes of metastatic prostate cancer that respond differently to treatment, information that could one day guide physicians in treating patients with the therapies best suited to their disease.

Newswise: Abdominal Fat Linked to Worse Outcomes for Black Breast Cancer Survivors
Released: 23-Sep-2021 7:05 AM EDT
Abdominal Fat Linked to Worse Outcomes for Black Breast Cancer Survivors
Rutgers Cancer Institute of New Jersey

Findings from a recent population based cohort study published online in JAMA Oncology show that Black women diagnosed with breast cancer who also have central obesity, which means excess body fat in the abdominal area, were more likely to die from breast cancer or any other cause than similar women who didn’t have central obesity.

Released: 22-Sep-2021 12:00 PM EDT
MD Anderson Research Highlights for September 22, 2021
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include a new method to measure breast cancer response, a new immunotherapy approach for multiple myeloma, characterization of the immune landscape of cholangiocarcinoma, a new contrast agent to improve molecular imaging techniques, and new treatment targets in breast, gynecologic and pancreatic cancers.

Released: 21-Sep-2021 12:20 PM EDT
Study: Catheter-Based Valve Replacement Helps More Heart Patients
Cedars-Sinai

After reviewing national data from nearly 160,000 patients, Cedars-Sinai researchers found that transcatheter aortic valve replacement, or TAVR, could be a favorable option for some low-risk patients with bicuspid aortic stenosis. The findings were published in the Journal of the American Medical Association (JAMA).

16-Sep-2021 3:00 PM EDT
Gun Violence Exposure Associated with Higher Rates of Mental Health-Related ED Visits by Children
Perelman School of Medicine at the University of Pennsylvania

Exposure to neighborhood gun violence is associated with increased odds of mental health-related pediatric Emergency Department (ED) visits among children living within four to five blocks of a shooting, according to research by the Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia, published today in JAMA Pediatrics.

Released: 20-Sep-2021 10:40 AM EDT
Lifesaving Trauma Skills Course Quickly and Significantly Sharpens Rarely Used Military Surgeons’ Skills
Uniformed Services University of the Health Sciences (USU)

Military surgeons must maintain a broad set of surgical skills to care for combat-related injuries, but during times of peace, these skills are rarely put to use. However, according to a new JAMA Surgery study, a two-day trauma skills course can significantly improve their proficiency and ensure they are able to continue providing optimal trauma care in combat. The study, “Surgical Skills Training and Assessment of Competency,” was led by researchers at the Uniformed Services University of the Health Sciences (USU) and published Sept. 15.

Released: 16-Sep-2021 3:50 PM EDT
Q&A: How a new imaging tool helps to better stage men with prostate cancer
University of California, Los Angeles (UCLA), Health Sciences

A paper detailing the method that led to the US Food and Drug Administration approval for PSMA PET imaging, which was led by UCLA and UCSF and their nuclear medicine teams, was recently published in JAMA Oncology.

Released: 15-Sep-2021 11:35 AM EDT
More Intensive and Personalized Strategies May be Needed for Weight Loss
University of Pennsylvania School of Nursing

Modest weight loss can lead to meaningful risk reduction in adults with obesity. Although both behavioral economic incentives and environmental change strategies have shown promise for initial weight loss, to date their efficacy alone or in combination have not been compared.

13-Sep-2021 7:30 AM EDT
Many Mothers May Have Delayed or Abandoned Plans for Additional Children Because of COVID-19 Pandemic
NYU Langone Health

Nearly half of New York City mothers who had been trying to become pregnant again before the coronavirus pandemic began stopped in the first few months of the outbreak, a new study shows.

Released: 15-Sep-2021 10:05 AM EDT
Dying at home, lack of healthcare contribute to COVID’s hidden death toll
Boston University School of Medicine

The official US death count for COVID-19 has now surpassed 650,000, but the true death toll is likely much higher.

Released: 14-Sep-2021 3:50 PM EDT
Do doctors treat pain differently based on their patients’ race?
University of California, Los Angeles (UCLA), Health Sciences

Physicians prescribed opioids more often to their white patients who complained of new-onset low back pain than to their Black, Asian and Hispanic patients during the early days of the national opioid crisis, when prescriptions for these powerful painkillers were surging but their dangers were not fully apparent.

Released: 13-Sep-2021 4:20 PM EDT
Turning 65 means a lot for Americans’ wallets, health spending study finds
Michigan Medicine - University of Michigan

Lowering the age when older adults can enroll in Medicare might save them a lot of money, even if the age drops only a year or two from the current age of 65, a new study suggests. Such a change could especially affect the small percentage of people in their early 60s who spend a major chunk of their disposable income on health costs.

Released: 10-Sep-2021 2:50 PM EDT
Health care experts propose policies to encourage shared responsibility between electronic health record developers and users
University of Texas Health Science Center at Houston

Developers of electronic health records (EHR) should create or modify their products to ensure that health care organizations can meet safety recommendations of the Safety Assurance Factors for EHR Resilience (SAFER) Guides, according to researchers with The University of Texas Health Science Center at Houston (UTHealth) and Baylor College of Medicine.

Released: 10-Sep-2021 2:40 PM EDT
UM School of Medicine Study Finds Social Isolation Increases Risk of Death in Seniors Following Critical Illness
University of Maryland School of Medicine

Those Admitted to the ICU for Care Are at Significantly Greater Risk of Dying if They Have Little Social Support

Released: 10-Sep-2021 11:05 AM EDT
UT Southwestern Review Finds Hysterectomy Can Be Avoided For Common Gynecological Condition
UT Southwestern Medical Center

Adenomyosis – an abnormal tissue growth into the muscular wall of the uterus that causes painful cramps and heavy or prolonged menstrual bleeding – is more common than generally appreciated, a review of the literature by gynecologists at UT Southwestern Medical Center revealed.

Released: 9-Sep-2021 2:15 PM EDT
Researchers: Majority of patients with Alzheimer’s disease would not have been eligible for clinical trials of new controversial Alzheimer’s drug    
Beth Israel Lahey Health

In a research letter in JAMA, physician-researchers at Beth Israel Deaconess Medical Center (BIDMC) found that the vast majority of patients who had a diagnosis of either cognitive impairment, Alzheimer’s disease, or Alzheimer’s disease related disorders, including cardiovascular disease, prior stroke, use of blood thinners, and age over 85 years, would have been excluded them from the aducanumab clinical trials.

Newswise:Video Embedded eyeglasses-for-school-kids-boosts-academic-performance
VIDEO
7-Sep-2021 1:00 PM EDT
Eyeglasses for School Kids Boosts Academic Performance
 Johns Hopkins University

Students who received eyeglasses through a school-based program scored higher on reading and math tests, Johns Hopkins researchers from the Wilmer Eye Institute and School of Education found in the largest clinical study of the impact of glasses on education ever conducted in the United States. The students who struggled the most academically showed the greatest improvement.

Released: 9-Sep-2021 4:05 AM EDT
Emoji are proposed as a powerful way for patients and doctors to communicate
Massachusetts General Hospital

Emoji, that universal lexicon of colorful and clever symbols meant to replace the written and spoken word, could be a valuable tool in the field of medicine, allowing patients to better communicate symptoms, concerns, and other clinically relevant information, argue a Massachusetts General Hospital (MGH) physician and others.

   
Released: 8-Sep-2021 6:15 PM EDT
New study on COVID-19 vaccinations in the largest US cities finds stark inequities
Columbia University, Mailman School of Public Health

In a study of the 9 largest U.S. cities, researchers at Columbia University Mailman School of Public Health found stark racial, ethnic, and socioeconomic inequities in COVID-19 vaccination rates across neighborhoods

Released: 8-Sep-2021 1:55 PM EDT
Online talk therapy can help mothers with postpartum depression
McMaster University

Researchers ran the online workshops for 403 mothers with PPD between April and October last year. The workshops took place live through Zoom and included group exercises, role plays and modules on the causes of PPD, identifying and changing difficult thinking patterns, and strategies to help shift behaviours to improve mood and anxiety.

Released: 8-Sep-2021 12:00 PM EDT
MD Anderson Research Highlights for September 8, 2021
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts.

Released: 7-Sep-2021 4:30 PM EDT
Study Shows Contact with Police May Be Detrimental to Health, Well-Being of Black Youth
Johns Hopkins Medicine

According to a Johns Hopkins Medicine study published today in JAMA Pediatrics, exposure to police — even in instances in which the officers are providing assistance — may be detrimental to the health and well-being of Black youth, especially males, and can be associated with poor mental health, substance use, risky sexual behaviors and impaired safety.

   
Released: 2-Sep-2021 11:40 AM EDT
Study: HPV Vaccination Will Reduce Throat and Mouth Cancers, But Overall Impact Will Take 25-Plus Years To See
Johns Hopkins Bloomberg School of Public Health

Vaccinations against human papillomavirus (HPV), a major cause of throat and back of mouth cancers, are expected to yield significant reductions in the rates of these cancers in the U.S., but will not do so until after 2045, according to a new modeling study from researchers at the Johns Hopkins Bloomberg School of Public Health

Released: 1-Sep-2021 4:05 PM EDT
Tip Sheet: Making clinical trials more inclusive, measuring COVID vaccine protection and new HIV vaccine results
Fred Hutchinson Cancer Center

SEATTLE — September 1, 2021 — Below are summaries of recent Fred Hutch research findings and other news.



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