A protein that helps the brain develop early in life can fight the mental fuzziness induced by sleep deprivation, according to researchers at Washington University School of Medicine in St. Louis.
Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer.
Tests of a new antibody-based “biosensor” developed by researchers at the Virginia Institute of Marine Science show that it can detect marine pollutants like oil much faster and more cheaply than current technologies. The device is small and sturdy enough to be used from a boat.
Researchers at Mount Sinai School of Medicine have made a critical discovery that may lead scientists to abandon the use of broad conventional ethnic labels—African-American, Hispanic, and Caucasian—to estimate a patient’s genetic risk for disease. This first-of-its kind study conducted with diverse patients receiving care at a single urban academic medical center, marks an important step in the clinical application of personalized medicine. The data are published online in the peer-reviewed journal PLoS ONE.
UCLA scientists have discovered a way to wake up the immune system to fight cancer by delivering an immune system-stimulating protein in a nanoscale container called a vault directly into lung cancer tumors, harnessing the body’s natural defenses to fight disease growth.
The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a University of Chicago study published in The Journal of Neuroscience.
Between 2001 and 2008, the annual rate of coronary artery bypass graft surgeries performed in the United States decreased by more than 30 percent, but rates of percutaneous coronary interventions (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) did not change significantly, according to a study in the May 4 issue of JAMA.
In a study conducted to examine the health outcomes related to salt intake, as gauged by the amount of sodium excreted in the urine, lower sodium excretion was associated with an increased risk of cardiovascular death, while higher sodium excretion did not correspond with increased risk of hypertension or cardiovascular disease complications, according to a study in the May 4 issue of JAMA.
Only about half of new drugs approved in the last decade had comparative effectiveness data available at the time of their approval by the U.S. Food and Drug Administration, and approximately two-thirds of new drugs had this information available when alternative treatment options existed, according to a study in the May 4 issue of JAMA.
Implementing structured exercise training, including aerobic, resistance or both, was associated with a greater reduction in hemoglobin A1c levels (a marker of glucose control) for patients with diabetes compared to patients in the control group, and longer weekly exercise duration was also associated with a greater decrease in these levels, according to results of an analysis of previous studies, published in the May 4 issue of JAMA.
The concepts now at the center of the health care quality movement, adopted in large part from the airline industry, should be used to standardize the processes and the equipment for in-flight medical emergencies, according to two Beth Israel Deaconess Medical Center physicians.
A small Johns Hopkins Children's Center study of children and teens with cystic fibrosis (CF) shows that simple exercise, individually tailored to each patient's preference and lifestyle, can help improve lung function and overall fitness.
By knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals’ calorie intake and weight, but also transformed their fat into a type that burns off more energy. The finding could lead to better obesity treatments for humans, the scientists report.
Young black men who have sex with men (MSM) get infected with HIV nearly five times more often than MSM from other races, even though they don't have more unprotected sex.
According to a new study, being overweight or obese during middle age may increase the risk of certain dementias. The research is published in the May 3, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.
One of the largest studies of its kind has found that people with coronary artery disease who have even a modest beer belly or muffin top are at higher risk for death than people whose fat collects elsewhere. The effect was observed even in patients with a normal Body Mass Index (BMI).
A study by UNC researchers finds that children with autism who had enlarged brains at age 2 continued to have enlarged brains at ages 4 and 5. However, this increased brain growth did not continue beyond age 2, and the changes detected at age 2 were due to overgrowth prior to that time point.
A study documents reduction in hospital mortality over ten years in a children's hospital without a Pediatric Emergency Medical Team (PMET), according to a report in the May issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
In England, the prevalence of adults with autism spectrum disorder (ASD) was estimated to be 9.8 per 1,000 population, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Military service members who screened positive for mental health disorders before deployment, or who were injured during deployment, were more likely to develop post-deployment posttraumatic stress disorder (PTSD) symptoms than their colleagues without these risk factors, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Scientists using magnetic resonance imaging (MRI) observed that the brains of children with autism spectrum disorder are larger than those without autism, but this difference appears related to increased rates of brain growth before 2 years of age, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Among children whose parents and other primary caregivers have limited English proficiency, there is an associated increased length of hospital stay and decreased number of home health care referrals for pediatric inpatients with infections requiring long-term antibiotics, according to a report in the May issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
For decades, an early human relative nicknamed Nutcracker Man because of his big, flat molars and powerful jaw. But a new University of Utah study shows Nutcracker Man didn’t eat nuts -- a discovery that upsets conventional wisdom about early humanity’s diet.
The production of wind energy in the U.S. over the next 30-50 years will be largely unaffected by upward changes in global temperature, say a pair of Indiana University Bloomington scientists who analyzed output from several regional climate models to assess future wind patterns in America's lower 48 states.
Competitive young athletes are under increasing pressure to play only one sport year round, but such specialization could increase the risk of injuries, a Loyola University Health System study has found.
Taking two medications for depression does not hasten recovery from the condition that affects 19 million Americans each year, researchers at UT Southwestern Medical Center have found in a national study.
Despite repeated warnings from dermatologists on the health dangers of tanning, results of a new survey by the American Academy of Dermatology (Academy) confirmed that a large percentage of Caucasian teen girls and young women admitted using tanning beds or intentionally tanning outdoors in the past year.
Pediatricians from Johns Hopkins Children's Center and elsewhere have discovered a link between low levels of vitamin D and anemia in children. The findings, presented on May 1 at the annual meeting of the Pediatric Academic Societies in Denver, Colo., show that vitamin D deficiency may play an important role in anemia.
Extremely premature babies fed human donor milk are less likely to develop the dangerous intestinal condition necrotizing enterocolitis(NEC) than babies fed a standard premature infant formula derived from cow's milk, according to research by investigators at the Johns Hopkins Children's Center and elsewhere.
Contrary to some earlier studies, a Loyola University Health System study has found that religious activity does not help protect against high blood pressure.
Judith Shaw of the University of Vermont's Vermont Child Health Improvement Program shares how Improvement Partnerships can support Quality Improvement activities and provide Maintenance of Certification for pediatricians.
Robotic surgery has become a mainstream tool for removing an ever-increasing variety of head and neck tumors. Now, a team of head and neck surgeons from Mayo Clinic has found robotic surgery can treat cancer in the narrow, hard-to-reach area beyond the tongue at the top of the voice box. Some patients were able to avoid further treatment with chemotherapy or radiation, and most could resume normal eating and speaking.
Combining computerized tomography (CT) with fluorodeoxyglucose positron emission tomography (FDG-PET) images results in significantly more defined tumor outlines and potentially different treatment options in head and neck cancer patients compared to using CT alone, according to research presented today, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. This symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North America (RSNA).
Proton radiography imaging used prior to and during proton treatments for pediatric cancer patients provides for more accurate treatment delivery and a lower dose of radiation compared to standard diagnostic X-rays and cone beam CT, according to a study presented today at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. The symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North America (RSNA).
A pelvic MRI scan with IV contrast and rectal balloon is highly effective in identifying local recurrence even at low PSA values in prostate cancer patients with a rising or persistently elevated PSA after prostatectomy, according to a study presented April 29, 2011, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. The symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North America (RSNA).
An annual mammogram is sufficient follow-up after breast conserving therapy (BCT) for breast cancer patients, according to a study presented today, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. This symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO) and Radiological Society of North America (RSNA).
Injecting a tissue spacer in the prostate-rectal inter-space is an effective way to reduce the rectal dose for prostate cancer patients receiving radiation therapy, according to research presented April 30, 2011, at the Cancer Imaging and Radiation Therapy Symposium in Atlanta. This symposium is sponsored by the American Society for Radiation Oncology (ASTRO) and Radiological Society of North America (RSNA).
Declining rates of hospitalization have discouraged primary care doctors from seeing their patients in the hospital and encouraged the growing use of “hospitalists,” a specialty focused on the care of hospitalized patients. Further developments in the field mean that frequently hospitalized patients also may need a specialist focused on their care.
Getting vaccinated against the flu lowers kidney transplant recipients’ risk of organ loss and death, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that concerns about the safety of the influenza vaccine in transplant recipients are unwarranted.
The angiotensin-converting enzyme (ACE) inhibitor drug, ramipril, is particularly effective in lowering the risk of end-stage renal disease (ESRD) in obese patients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
Researchers eavesdropping on complex signals emanating from a remote Wisconsin lake have detected what they say is an unmistakable warning — a death knell — of the impending collapse of the lake’s aquatic ecosystem.
In a paper to be published today [April 29, 2011] in the journal “Science,” a team of Boston University researchers under the direction of Michael Hasselmo, professor of psychology and director of Boston University’s Computational Neurophysiology Laboratory, and Mark Brandon, a recent graduate of the Graduate Program for Neuroscience at Boston University, present findings that support the hypothesis that spatial coding by grid cells requires theta rhythm oscillations, and dissociates the mechanisms underlying the generation of entorhinal grid cell periodicity and head-direction selectivity.
Whitehead Institute scientists report that two proteins once thought to have only supporting roles, are the true “stars” of the kinetochore assembly process in human cells. The kinetochore is vital to proper DNA distribution during cell division.
In modern ecology, the removal or addition of a predator to an ecosystem can produce dramatic changes in the population of prey species. For the first time, scientists have observed the same dynamics in the fossil record, thanks to a mass extinction that decimated ocean life 360 million years ago.
A novel strategy developed by autism researchers at the University of California, San Diego School of Medicine, called “The One-Year Well-Baby Check Up Approach,” shows promise as a simple way for physicians to detect cases of Autism Syndrome Disorder (ASD), language or developmental delays in babies at an early age.
Women are at higher risk than men of developing kidney damage after undergoing a coronary angiogram, according to a Henry Ford Hospital study.
Researchers found that women are 60 percent more likely than men to develop radiocontrast-induced nephropathy (RCIN), an adverse side effect that causes kidney dysfunction within 24 to 72 hours after patients are administered an iodine contrast dye during the common heart imaging test.
Group appointments where doctors see several people for a longer time may be feasible for Parkinson’s disease, according to a new study published in the April 27, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology (AAN).
Dana-Farber Cancer Institute scientists have developed a technique that can cause attack cells in cancer patients live longer in a patients' bloodstream, helping to increase survival times.