Persons with an addictive-like eating behavior appear to have greater neural activity in certain regions of the brain similar to substance dependence, including elevated activation in reward circuitry in response to food cues, according to a report posted online today that will appear in the August print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
People who migrate to the United States from Mexico have a significantly higher risk of developing depressive or anxiety disorders than family members of migrants who remain in Mexico, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Low levels of household income are associated with several lifetime mental disorders and suicide attempts, and a decrease in income is associated with a higher risk for anxiety, substance use, and mood disorders, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Fossil teeth of African animals show that during the past 10 million years, different plant-eating critters began grazing on grass at different times as many switched from a salad-bar diet of tree leaves and shrubs, says a University of Utah study.
Scientists from the Morgridge Institute for Research, the University of Wisconsin-Madison, the University of California and the WiCell Research Institute moved gene therapy one step closer to clinical reality by determining that the process of correcting a genetic defect does not substantially increase the number of potentially cancer-causing mutations in induced pluripotent stem cells.
A species of algae long known to associate with spotted salamanders has been discovered to live inside the cells of developing embryos, say scientists from the U.S. and Canada, who report their findings in this week's PNAS. This is the first known example of a eukaryotic algae living stably inside the cells of any vertebrate.
Vanderbilt researchers, who helped organize a consortium including the University of Pennsylvania School of Medicine, the University of Miami Miller School of Medicine, and the Boston University School of Medicine, have identified four new genes linked to Alzheimer’s disease. The findings, released today by Nature Genetics, effectively double the number of genes known to contribute to the disease, according to Jonathan Haines, Ph.D., director, Vanderbilt Center for Human Genetics Research.
Judy E. Garber, M.D., M.P.H., was inaugurated today as president of the American Association for Cancer Research at the AACR 102nd Annual Meeting 2011. This year’s meeting theme is “Innovation and Collaboration: The Path to Progress.”
Researchers at McMaster University and Hamilton Health Sciences have found accessing blocked arteries through the forearm compared to groin led to fewer vascular complications and similar success rates for angioplasty.
As cancer continues to affect one in two men and one in three women, researchers are increasing their knowledge on the known risk factors for cancer both environmentally and genetically.
Women with ovarian cancer who have the BRCA2 gene mutation are more likely to survive the malignancy than women with the BRCA1 mutation, or women without either mutation.
Among people with AIDS, the risk of stomach and esophageal malignancies is higher than among the general population, according to study results presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Heavy beer drinkers who have a specific genetic variant in the cluster of three genes that metabolize alcohol are at significantly higher risk of developing non-cardia gastric cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Scientists from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are working on a series of genetic analyses that suggest the underlying differences among racial groups are present not just in tumors, but in normal tissue as well. Lisa Baumbach, Ph.D., associate research professor, and colleagues will present the full study results at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Researchers directed by Dr. Laurent Mottron at the University of Montreal’s Centre for Excellence in Pervasive Development Disorders (CETEDUM) have determined that people with autism concentrate more brain resources in the areas associated with visual detection and identification, and conversely, have less activity in the areas used to plan and control thoughts and actions.
Cancer is at its most treatable when caught early, so scientists are increasing their focus on innovative diagnostic methods that, hopefully, will lead to higher cure rates.
A panel of biomarkers appears to be able to identify the presence of lung cancer in the blood samples of people who have never smoked, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Researchers investigating a novel biomarker test believe it is the most accurate yet in detecting proteins secreted from tumors caused by exposure to asbestos. Study results of this aptamer proteomic technology were presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Breast cancer risk can be assessed by examining the epithelial cells found in breast milk, according to preliminary study results presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Researchers at NYU Langone Medical Center have investigated a novel protein test to detect early-stage, asbestos-related pulmonary cancer. The test can accurately identify proteins secreted from cancerous tumors caused by asbestos exposure. The study was presented at the American Association for Cancer Research 102nd Annual Meeting 2011 on April 4th.
Nicotine at doses similar to those found in most nicotine replacements therapies did not increase lung cancer tumor incidence, frequency or size, according to results of a mouse study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
The use of aspirin at least once per month is associated with a significant decrease in pancreatic cancer risk, according to results of a large case-control study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Researchers with the International Agency for Research on Cancer (IARC) have found that people with lung cancer were significantly more likely to have several high-risk forms of human papillomavirus (HPV) antibodies compared to those who did not have lung cancer. These results, which were presented at the AACR 102nd Annual Meeting 2011, held April 2-6, indicate that HPV antibodies are substantially increased in people with lung cancer.
Medicare coverage and nationwide utilization of computed tomographic colonography (CTC), commonly referred to as virtual colonoscopy, has tripled in recent years, according to a study in the April issue of the Journal of the American College of Radiology (www.jacr.org). CTC employs virtual reality technology to produce a three-dimensional visualization that permits a thorough and minimally invasive evaluation of the entire colon and rectum. CT colonography is an alternative to conventional optical colonoscopy for colorectal cancer screening and diagnosis.
Results of the NIH-AARP Diet and Health Study revealed that diabetes is associated with lower risk of prostate cancer in men but with higher risk of other cancers in both men and women. The data, to be presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, also showed an association between diabetes and higher cancer mortality rates.
Smoking increases the risk of breast cancer, but the risk differs by obesity status in postmenopausal women, according to data from an analysis of the Women’s Health Initiative observational study.
Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
The U.S. Congress will soon be facing another budget showdown as their sixth continuing resolution expires on April 8, 2011. While the entire government has been without permanent appropriations for nearly six months, the House Republicans and Senate Democrats continue to remain far apart on resolving the fiscal year (FY) 2011 budget.
In the largest study of its kind, researchers from a consortium of 44 universities and research institutions in the United States, including Rush University Medical Center, identified four new genes linked to Alzheimer’s disease. Each gene individually adds to the risk of having this common form of dementia later in life.
Promising new research reveals a potentially highly effective treatment for heterotopic ossification (HO), a painful abnormal buildup of bone tissue. HO has two main forms—one in children, another in wounded soldiers.
Researchers from a consortium that includes Columbia University Medical Center identified four new genes linked to late-onset Alzheimer’s disease, each of which adds to the risk of developing this most common form of the disease. Together they offer a portal into the causes of Alzheimer’s. Their identification will help researchers find ways to determine who is at risk of developing the disease and to identify proteins and pathways for drug development.
Researchers at Columbia University Medical Center have developed a new way to stimulate neuron production in the adult mouse brain, demonstrating that neurons acquired in the brain's hippocampus during adulthood improve certain cognitive functions.
Cancer Discovery, the newest journal in the robust publication program of the American Association for Cancer Research, will debut at the AACR 102nd Annual Meeting 2011, held here from April 2-6.
Scientists have uncovered a genetic characteristic of metastatic prostate cancer that defines a rare sub-type of this disease. These findings are published in Cancer Discovery, the newest journal of the American Association for Cancer Research, which will debut at the AACR 102nd Annual Meeting 2011, held April 2-6.
Scientists at the Dana Farber Cancer Institute have identified a mutation in the DDR2 gene that may indicate which patients with squamous cell lung cancer will respond to dasatinib.
A study published in Cancer Discovery, the newest journal of the American Association for Cancer Research, debuting here at the AACR 102nd Annual Meeting 2011, held April 2-6, showed how evaluating the immune response in the tumor microenvironment may help researchers better target therapy in breast cancer.
Scientists have identified digoxin as a possible therapy for prostate cancer, using a combination of laboratory science and epidemiology that is unprecedented in its cooperative nature.
Johns Hopkins scientists and their colleagues paired laboratory and epidemiologic data to find that men using the cardiac drug, digoxin, had a 24 percent lower risk for prostate cancer. The scientists say further research about the discovery may lead to use of the drug, or new ones that work the same way, to treat the cancer.
Using new genetic information, scientists have linked a commonly found human genetic variant with both longer telomeres and reduced risk of bladder cancer, according to findings presented at the AACR 102nd Annual Meeting 2011, held April 2-6, and simultaneously published in Cancer Prevention Research, a journal of the American Association for Cancer Research.
Results of a study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, lend credence to the idea that improving quality of life affects stress-related biological markers and possibly the health of people with cancer.
Evidence continues to build that telomeres, cell endings that fray as we age, are affected by stress and are predictive of cancer risk. Scientists will present new groundbreaking research in this area of study at an AACR 102nd Annual Meeting 2011 press conference held on Sunday, April 2 at 2:00 p.m. ET in room W313 of the Orange County Convention Center.
A common genetic variation links to both bladder cancer risk and to the length of protective caps found on the ends of chromosomes, scientists at The University of Texas MD Anderson Cancer Center reported today at the AACR 102nd Annual Meeting.
The American Association for Cancer Research Annual Meeting continues to be a showcase for the most cutting edge science in cancer, and this year’s meeting, held here April 2-6, will include an increased focus on clinical trials that will impact patient care.
A new hedgehog pathway inhibitor demonstrated efficacy in preventing and treating basal cell cancer among patients with basal cell nevus syndrome, a rare inheritable disease, according to Phase II data presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Scientists are continuing their work on the Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination trial — known more commonly as the BATTLE trial — and presented updated results at the AACR 102nd Annual Meeting 2011, held here April 2-6.
The combination of two compounds that inhibit two of the most frequently mutated cancer pathways is showing promise in an ongoing Phase I trial, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Scientists have identified a biomarker for measuring the success of lung cancer chemoprevention, an emerging frontier in the fight against this disease that has long been stymied by a lack of measureable outcomes. These study results were presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
In one of the largest cancer genomics investigations reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. This comparison allowed researchers to find mutations that only occurred in the cancer cells.
In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. They uncovered incredible complexity in the cancer genomes, but also got a glimpse of new routes toward personalized medicine.
Analysis published this week in the journal Science shows how declines of bat populations caused by a new wildlife disease and fatalities at industrial-scale wind turbines could lead to substantial economic losses on the farm.
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