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24-May-1999 12:00 AM EDT
Fast, Controllable Way to Study Molecular Interactions
UT Southwestern Medical Center

A molecule that is extremely sensitive to light has proved a highly efficient way of initiating bonding of two proteins. UT Southwestern Medical Center at Dallas researchers who designed this cross-linking reagent and technique said this will be an important tool in studying multiprotein complexes.

22-May-1999 12:00 AM EDT
Very-low-fat Diet May Compromise Immunity
University at Buffalo

Trained runners who severely limit the amount of fat in their diets may be suppressing their immune system and increasing their susceptibility to infections and inflammation, a University at Buffalo study has shown.

Released: 22-May-1999 12:00 AM EDT
Possible Reason for Rare, Accelerated Aging Discovered
University of Iowa

People with progeria have extremely low levels of antioxidant enzymes, University of Iowa researchers reported in Biochemical and Biophysical Research Communications.

Released: 22-May-1999 12:00 AM EDT
5-18-99 Tipsheet, Annals of Internal Medicine
American College of Physicians (ACP)

1-Patients Prefer Making Advance Care Decisions with Family, Not Physicians; 2- Comparisons of Two Anticoagulants to Treat Deep Vein Blood Clots; 3- Special Curriculum Helps Doctors Communicate with Patients of Other Cultures; 4- New Paper Guides Physicians Treating Patients Without Decision-Making Capacity.

21-May-1999 12:00 AM EDT
Novartis Pharmaceuticals

Data from three separate studies demonstrate that the angiotensin II receptor blocker Diovan* (valsartan), with and without hydrochlorothiazide treatment, provides long-term and consistent blood pressure control with excellent tolerability. The data were presented at the 14th Annual Meeting of the American Society of Hypertension in New York.

Released: 21-May-1999 12:00 AM EDT
Cancer Role of Mutated Gene Revealed
University of North Carolina Health Care System

The molecular role in cancer development of a mutated tumor suppressor gene known as ARF has been discovered by University of North Carolina at Chapel Hill scientists. The new findings help clarify why ARF is the second most frequently mutated gene in human cancers.

Released: 21-May-1999 12:00 AM EDT
Seroquel Improves Cognitive Function
AstraZeneca

The atypical antipsychotic SEROQUEL(R) (quetiapine fumarate) Tablets appears to improve cognitive function and reduce weight gain, suggests studies presented at the American Psychiatric Association's Annual Meeting.

Released: 21-May-1999 12:00 AM EDT
Discovery of a Molecule That Controls Bile Acids
UT Southwestern Medical Center

The discovery that a nuclear receptor controls the production of bile acids and works within a pathway that speeds up destruction of cholesterol may lead to new cholesterol drugs, UT Southwestern researchers reported in today's issue of Science.

Released: 21-May-1999 12:00 AM EDT
Medication Improves Psychotic Symptoms
AstraZeneca

Findings from studies presented at the American Psychiatric Association's Annual Meeting show that SEROQUEL(r) (quetiapine fumarate) Tablets show promise for the relief of psychotic symptoms for Alzheimer's or Parkinson's Disease sufferers.

Released: 21-May-1999 12:00 AM EDT
Throw Away Food Labeled Fat-Free
Vanderbilt University

New research shows that too many carbohydrates in a diet suppresses the body's ability to burn fat, according to Vanderbilt University researchers.

Released: 21-May-1999 12:00 AM EDT
Controversial "Slotting Fees" Examined
University of Notre Dame

A new study coauthored by a University of Notre Dame marketing professor provides the first comprehensive academic analysis of "slotting fees" -- the controversial practice of retailers and wholesalers requiring a payment from manufacturers before agreeing to allocate shelf or warehouse space to the manufacturers' product.

Released: 21-May-1999 12:00 AM EDT
Higher Interest Rates Predicted
Georgia State University, J. Mack Robinson College of Business

Rapid consumer spending coupled with a decrease in housing construction this year is increasing the possibility of higher interest rates by the Federal Reserve by its August meeting, according to the latest projections by Dr. Donald Ratajczak, director of the Economic Forecasting Center at Georgia State University.

Released: 21-May-1999 12:00 AM EDT
Early Detection, Preserving Eyesight from Glaucoma
Mayo Clinic

Early diagnosis of glaucoma is important in preserving eyesight, a new Mayo Clinic study confirms. The study showed that if a person had eye damage from glaucoma at the time of their diagnosis, there was a 54 percent chance of becoming legally blind in at least one eye over a 20-year period despite treatment, and a 22 percent chance of becoming legally blind in both eyes.

Released: 21-May-1999 12:00 AM EDT
Inner-City Hepatitis C Patients, Chronic Disease Risk
Emory University Woodruff Health Sciences Center

In a study of inner-city patients with chronic hepatitis C infections, Emory University researchers have found that certain risk factors not only increase these individuals' chances for the development of acute hepatitis C virus, but also make them particularly vulnerable to developing the chronic form of the disease.

Released: 21-May-1999 12:00 AM EDT
Information Labels for Electricity
University of Maine

There are labels for everything we buy, from clothes to long-distance telephone service. In the near future, electricity customers in Maine and elsewhere will see new information labels developed on the basis of a research project involving the University of Maine, a Maine-based non-profit organization and three federal agencies.

Released: 21-May-1999 12:00 AM EDT
How Nature Produces Cholesterol-Lowering Lovastatin
University of Wisconsin-Madison Department of Medicine

Scientists know that a fuzzy fungus similar to the mold that grows on stale bread and over-ripe fruit produces lovastatin, the natural substance that lowers cholesterol in humans. Now pharmacy researchers at the University of Wisconsin-Madison know how the fungus makes it.

Released: 21-May-1999 12:00 AM EDT
Porous Silicon Lights, New Analytical Devices
Purdue University

Porous silicon, a roughed-up version of the material that paved the way for the computer industry, is now smoothing the way for new types of chemical and medical analyses, including micro-laboratories designed to fit on a computer chip.

Released: 21-May-1999 12:00 AM EDT
Chronic Skin Condition, More than Skin Deep
National Psoriasis Foundation (NPF)

For the nearly 7 million Americans suffering from psoriasis, the disease is more than just dry, cracking, scaly and sometimes bleeding skin. It can also leave severe emotional scars.

Released: 21-May-1999 12:00 AM EDT
Euro Will Weaken before Strengthening
Conference Board

The euro may weaken before rebounding toward the end of the year and into 2000, as European economic growth picks up and interest rates rise, according to an analysis released today by The Conference Board.

Released: 21-May-1999 12:00 AM EDT
Americans Choose Life-Threatening Disease Over Skin Condition
National Psoriasis Foundation (NPF)

Nearly half of all Americans would rather have a medical condition like hypertension, asthma or diabetes than a skin condition like psoriasis, according to a national survey.

Released: 21-May-1999 12:00 AM EDT
Video Game Violence Minimally Affects Kids
Purdue University

A Purdue University expert on media and children believes kids are attracted to video games not so much by the violence, but because they present puzzles or problems to solve. He reviewed 27 studies on video games and found their overall effect on aggressiveness in children was not great.

20-May-1999 12:00 AM EDT
The "Break Even" Cost of Kidney Transplants Is Shrinking
University of Maryland Medical Center

The cost of a kidney transplant has dropped so significantly that University of Maryland School of Medicine researchers say it is cheaper to have a transplant than to stay on dialysis for more than two and a half years, even among the sickest patients.

Released: 20-May-1999 12:00 AM EDT
APA Annual Meeting Highlights Thursday, 5-20-99
American Psychiatric Association (APA)

1- ADHD and Antisocial Personality Disorder as Independent Predictors of Alcoholism 15 Years Later, 2- Missed Initial Visits in a Managed Care Network, 3- Treatment of Generalized Social Phobia.

Released: 20-May-1999 12:00 AM EDT
Respiratory Journal News for May 1999
American Thoracic Society (ATS)

1. Patients on prolonged mechanical ventilation show very low one-year survival and functional capabilities; 2. pulmonary rehab as integral to clinical management of respiratory disease, 3. new assessment tool for lung cancer patients undergoing resection of tumors.

Released: 20-May-1999 12:00 AM EDT
Undergrads Build Device for Army Tests
 Johns Hopkins University

Three undergraduate engineers at Johns Hopkins have invented a device to help the Army test the combat-durability of critical electronic and mechanical parts.

Released: 20-May-1999 12:00 AM EDT
Lowering Cholesterol May Improve Red Cell Function
University of Minnesota

Researchers at the University of Minnesota have found that a high plasma cholesterol level leads to an increased density of red cell membranes. When this happens, oxygen flow through the membrane is impaired.

Released: 20-May-1999 12:00 AM EDT
"Smart Concrete" Would Determine Weight of Trucks
University at Buffalo

Truck-weighing stations on highways could become a thing of the past as a result of a new application for "smart concrete" developed by University at Buffalo engineers.

Released: 20-May-1999 12:00 AM EDT
Natural Hazards Response Requires New Approach
National Science Foundation (NSF)

The cost of natural hazards in the United States has averaged as much as $1 billion per week since 1989 and is expected to keep rising, according to a new study released at the National Press Club in Washington, D.C.

Released: 20-May-1999 12:00 AM EDT
Extinction-Threatened Bird Species Found in Unexpected Places
University of Arkansas, Fayetteville

University of Arkansas researcher Tom Brooks and colleagues Lisa Manne and Stuart Pimm of the University of Tennessee have overturned a long-held belief that island bird species are more vulnerable to extinction than their continental counterparts.

Released: 20-May-1999 12:00 AM EDT
Inhibiting Key Enzyme Slows Huntington's Disease Progression in Mice
Emory University Woodruff Health Sciences Center

Emory University School of Medicine and Harvard Medical School scientists have discovered that an enzyme called caspase-1, found in the brains of humans and mice, may play a critical role in the progression of Huntington's disease. By inhibiting the enzyme, they have significantly delayed the progression of Huntington's disease in mice, they reported in the May 20 issue of Nature.

Released: 20-May-1999 12:00 AM EDT
NBA Draft Lottery--Are Teams Losing to Win?
Baylor University

With Saturday's National Basketball Association draft lottery looming, two Baylor University economists have released their findings on tournament incentives in pro basketball, specifically the time-honored notion that teams "lose to win."

   
Released: 20-May-1999 12:00 AM EDT
Animal Experimentation: Special Report Tipsheet from New Scientist
New Scientist

To find out where the British people draw the line on research with animals, New Scientist commissioned Market & Opinion Research International (MORI) to conduct the most complete survey yet on public attitudes to the most controversial debate in science.

Released: 20-May-1999 12:00 AM EDT
Public Housing and Welfare Reform
 Johns Hopkins University

Media advisory: Sandra Newman of the Johns Hopkins Institute for Policy Studies has edited a new book on the interrelationship of assisted housing policy and welfare reform. She is available for interviews on the issue.

Released: 20-May-1999 12:00 AM EDT
TERRIERS Satellite Experiencing Difficulties
Boston University

The TERRIERS satellite, built by students at Boston University and launched Tuesday morning, so far has not been able to orient itself so that its solar panels fully face the sun and seems to have run out of battery power, according to project managers.

Released: 20-May-1999 12:00 AM EDT
Bipolar and Schizoaffective Disorders Treatment
AstraZeneca

Research presented at the American Psychiatric Association's Annual Meeting today suggests SEROQUEL(r) (quetiapine fumarate) tablets may be an effective treatment for bipolar disorder and schizoaffective disorder.

Released: 20-May-1999 12:00 AM EDT
Star Wars Technology, Closer to Home than You Think
NASA Marshall Space Flight Center

Although technology you see in a Star Wars movie may seem like futuristic fantasy, check out some research NASA is doing today to turn some of that fantasy into fact.

Released: 20-May-1999 12:00 AM EDT
Stormy Weather on Mars
NASA Marshall Space Flight Center

NASA's Hubble Space Telescope spotted a gigantic storm swirling near the Red Planet's north pole.

Released: 20-May-1999 12:00 AM EDT
Gene Therapy Success in Prostate Cancer, Preliminary Study
University of Texas MD Anderson Cancer Center

Findings of the Phase I medical study may have a huge impact on future treatments for the disease, especially for men with localized advanced prostate cancer, say Researchers at the University of Texas M. D. Anderson Cancer Centerr.

Released: 20-May-1999 12:00 AM EDT
Cancer Patients Who Continue to Smoke Beware
University of Texas MD Anderson Cancer Center

Smokers successfully treated for head and neck squamous cell cancer have greater chances of getting another cancer or having the cancer recur if they do not quit smoking, according to study at the University of Texas M. D. Anderson Cancer Center.

Released: 20-May-1999 12:00 AM EDT
Tips from M. D. Anderson Researchers at ASCO
University of Texas MD Anderson Cancer Center

1- effectiveness of first oral chemotherapy for colon cancer; 2- new agent's promise against most serious brain tumors; 3- Taxotere increases survival rate for patients with non-small cell lung cancer.

Released: 19-May-1999 12:00 AM EDT
Special Thin Films Developed in Space for Future
NASA Marshall Space Flight Center

NASA Scientists at Marshall Space Flight Center are conducting space research to build components needed for the next step: hybrid electro-optic computers.

19-May-1999 12:00 AM EDT
Tip Sheet from Johns Hopkins Oncology Center
Johns Hopkins Medicine

This tip sheet highlights research news from Johns Hopkins that are either the subject of presentations or ongoing issues that provide context for presentations at the annual meeting of the American Society of Clinical Oncology.

19-May-1999 12:00 AM EDT
Engineered corn can kill monarch butterflies
Cornell University

An increasingly popular commercial corn, genetically engineered to produce a bacterial toxin to protect against corn pests, has an unwanted side effect: Its pollen kills monarch butterfly larvae in laboratory tests, according to a report by Cornell University researchers.

19-May-1999 12:00 AM EDT
New Procedure Makes a Successful Transplant Possible
University of Maryland Medical Center

Six critically ill people on kidney dialysis have been able to receive a kidney transplant and a new chance at life thanks to a procedure at the University of Maryland Medical Center that cleansed their blood of harmful rejection antibodies.

Released: 19-May-1999 12:00 AM EDT
Tipsheet from Society for Breast Imaging Postgraduate Course
Society of Breast Imaging (SBI)

Highlights of the Society for Breast Imaging and the American College of Radiology's jointly sponsored postgraduate course in Boston May 26-29: 1- mandatory accreditation, 2- ductal cancer in situ, 3- mammogram interpretation, 4- breast cancer diagnosis with computers, 5- nonmammographic detection, 6- intervention and treatment, 7- digital mammography, 8- screening mammography.

Released: 19-May-1999 12:00 AM EDT
APA Annual Meeting Highlights Wednesday, 5-19-99
American Psychiatric Association (APA)

1- Clinical Practice' Meteorological Influence on Migraine Headaches, 2- Unrecognized Dementia in Geriatric Patients, 3- Risk for Eating Disorders in Athletes 4- Lunch with the APA Leadership

Released: 19-May-1999 12:00 AM EDT
Race and Socioeconomic Status Affect Antidepressant Access
Washington State University

Antidepressants are prescribed to black and Hispanic patients suffering from depression at less than half the rate they are prescribed to similarly diagnosed white patients, a new study by Washington State University researchers concludes.

Released: 19-May-1999 12:00 AM EDT
New Drug Delivery Technology Yields Cancer Drug
University of California San Diego

Researchers with University of California, San Diego report success in using a new technology to develop a sustained-release formulation of the cancer drug cytarabine (ara-C). The new formulation, called DepoCyt, produced a significantly better response rate than standard ara-C in patients with lymphomatous meningitis.

Released: 19-May-1999 12:00 AM EDT
Promise for Non-Hodgkin's Lymphoma Drug
Roswell Park Comprehensive Cancer Center

Preliminary results of a pilot and a Phase II study using Rituximab to treat non-Hodgkin's lymphoma were presented at the American Society of Clinical Oncology meeting in Atlanta. These studies show Rituximab to be effective when combined with Fludarabine (a chemotherapy) and when used alone dosed in an extended eight-infusion regimen. Both trials were conducted at Roswell Park Cancer Institute and other cancer centers.



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