A mother’s willingness to sacrifice her own health and safety for the sake of her children is a common narrative across cultures – and by no means unique to humans alone. Female polar bears starve, dolphin mothers stop sleeping and some spider moms give themselves as lunch for their crawly babies’ first meal.
A 20-year study following 110,645 workers who helped clean up after the 1986 Chernobyl nuclear power plant accident in the former Soviet territory of Ukraine shows that the workers share a significant increased risk of developing leukemia. The results may help scientists better define cancer risk associated with low doses of radiation from medical diagnostic radiation procedures such as computed tomography scans and other sources.
Laws that end smoking at work and other public places result in significantly fewer hospitalizations for heart attacks, strokes, asthma and other respiratory conditions, a new UCSF analysis has found.
Universities not only provide the ideal petri dish for cultivating bioscience with commercial potential, but have a moral obligation to do so, given the opportunity to translate public funding into health and jobs, according to a new case study by UCSF researchers.
Most liver transplant candidates who died or were removed from the transplant list actually received one or more liver donation offers, according to a recent UCSF study.
The unexpected survival of embryonic neurons transplanted into the brains of newborn mice in a series of experiments at the University of California, San Francisco (UCSF) raises hope for the possibility of using neuronal transplantation to treat diseases like Alzheimer’s, epilepsy, Huntington’s, Parkinson’s and schizophrenia.
A Phase I clinical trial led by investigators from the University of California, San Francisco and sponsored by Stem Cells Inc., showed that neural stem cells successfully engrafted into the brains of patients and appear to have produced myelin.
Now, armed with a new $10 million grant, a multi-center “dream team’’ of scientists, led by UCSF, is embarking on a groundbreaking undertaking into personalized medicine. The goal: to overcome therapeutic resistance in the disease and revolutionize treatment for patients with advanced prostate cancer.
Indoor tanning beds can cause non-melanoma skin cancer – and the risk is greater the earlier one starts tanning, according to a new analysis led by UCSF.
A $750,000 gift from the John and Marcia Goldman Foundation is spurring a UCSF-led effort to create the first implantable artificial kidney for patients with kidney failure.
An isolated outbreak of a deadly disease known as acute hemorrhagic fever, which killed two people and left one gravely ill in the Democratic Republic of Congo in the summer of 2009, was probably caused by a novel virus scientists have never seen before.
Top box office films last year showed more onscreen smoking than the prior year, reversing five years of steady progress in reducing tobacco imagery in movies, according to a new UCSF study.
Students at UCSF have just begun studies in a new, state-of-the-art anatomy learning center equipped with interactive iPad textbooks, giant video displays and roving cameras that will allow them to observe, discover and come to understand, in a new way, the complex architecture of the human body.
Secondhand smoke is accountable for 42,000 deaths annually to nonsmokers in the United States, including nearly 900 infants, according to a new UCSF study.
The University of California, San Francisco has received a $20 million gift from philanthropist Chuck Feeney to build a new hub for Global Health Sciences at the UCSF Mission Bay campus. Feeney made the gift through The Atlantic Philanthropies, the foundation he created in 1982.
A once-promising discovery linking prostate cancer to an obscure retrovirus derived from mice was the result of an inadvertent laboratory contamination, a forensic analysis of tissue samples and lab experiments – some dating back nearly a decade – has confirmed.
A new study that identifies ways to reduce the factors that lead to an asthma attack gives hope to asthma sufferers. A UCSF researcher and his colleagues believe they have found a way to help asthma sufferers by impeding the two most significant biological responses that lead to an asthma attack.
Mental health professionals, who often are tasked with evaluating and managing the risk of violence by their patients, may benefit from a simple tool to more accurately make a risk assessment, according to a recent study conducted at the University of California, San Francisco.
A common bacteria ever-present on the human skin and previously considered harmless, may, in fact, be the culprit behind chronic sinusitis, a painful, recurring swelling of the sinuses that strikes more than one in ten Americans each year, according to a study by scientists at the University of California, San Francisco.
For two decades, asthma treatment for millions of people with a milder form of the disease has consisted of daily inhaled steroid medicine to reduce inflammation. Now, a new study has found that asthmatics who take the low-dose medication as a daily routine do no better than those who turn to their inhalers only when they have symptoms.
Ronald Vale, PhD, of the University of California, San Francisco was one of three scientists today awarded the 2012 Albert Lasker Basic Medical Research Award. The researchers’ work, beginning more than three decades ago, has helped illuminate several critical aspects of life—how the heart beats and how cells transport material around internally.
A protein called “clathrin,” which is found in every human cell and plays a critical role in transporting materials within them, also plays a key role in cell division, according to new research at the University of California, San Francisco.
Despite nearly three decades of conflict, Sri Lanka has succeeded in reducing malaria cases by 99.9 percent since 1999 and is on track to eliminate the disease entirely by 2014.
A multi-center study of intensive care units (ICU) led by UCSF faculty has received a Gordon and Betty Moore Foundation grant of $2.1 million. The study of ICUs, including two at UCSF, aims to better understand the nature of team-based care and patient involvement in ICU settings.
People who carry a “G” instead of an “A” at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the University of California, San Francisco and Mayo Clinic.
UCSF researchers found that poor HIV-infected individuals living in San Francisco are significantly more likely to visit emergency rooms and to have hospital stays if they lack access to food of sufficient quality and quantity for a healthy life.
A novel virus has been identified as the possible cause of a common but mysterious disease that kills a significant number of pet snakes all over the world, thanks to research led by scientists at the University of California, San Francisco (UCSF)—and three snakes named Juliet, Balthazar and Larry.
Depression was linked with an increased risk of peripheral artery disease (PAD) in a study of more than one thousand men and women with heart disease conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
At its most fundamental level, diabetes is a disease characterized by stress—microscopic stress that causes inflammation and the loss of insulin production in the pancreas, and system-wide stress due to the loss of that blood-sugar-regulating hormone.
Marin County, California has one of the highest rates of breast cancer in the world, a fact that scientists know has nothing to do with the land itself but with some other, unknown factor. A new study that analyzed mouth buccal cell samples stored frozen at the University of California, San Francisco (UCSF) suggests what this factor may be: a genetic trait present among women within the county’s predominantly white population.
Almost half of adults with type 2 diabetes report acute and chronic pain, and close to one quarter report neuropathy, fatigue, depression, sleep disturbance and physical or emotional disability, according to a study of more than 13,000 adults.
Hospitals in areas with large minority populations are more likely to be overcrowded and to divert ambulances, delaying timely emergency care, according to a multi-institutional study focused on California.
Is it possible for a health care system to redesign its services to better educate patients to deal with their immediate health issues and also become more savvy consumers of medicine in the long run?
As moms have always known, a good night’s sleep is crucial to good health -- and now a new study led by a UCSF researcher shows that poor sleep can reduce the effectiveness of vaccines.
Adults with HIV in rural sub-Saharan Africa who receive antiretroviral drugs early in their infection may reap benefits in their ability to work and their children's ability to stay in school, according to a first-of-its-kind clinical study in Uganda that compared socioeconomic outcomes with CD4+ counts—a standard measure of health status for people with HIV.
Raising levels of the neurotransmitter dopamine in the frontal cortex of the brain significantly decreased impulsivity in healthy adults, in a study conducted by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco.
Women with diabetes are just as likely to be interested in, and engage in, sexual activity as non-diabetic women, but they are much more likely to report low overall sexual satisfaction, according to a UCSF study.
Population-wide levels of HIV virus dropped substantially between 2011 and May 2012 in a rural part of southwestern Uganda, the site of two community health campaigns led by doctors at the University of California, San Francisco (UCSF), San Francisco General Hospital and Trauma Center (SFGH) and Makerere University in Kampala, Uganda.
In January, 2012, the U.S. Food and Drug Administration (FDA) issued new guidelines on dosing of an HIV medication used to treat people infected with both HIV and tuberculosis (TB) because of a potential interaction between two of the main drugs used to treat each disease.
A clinical study in a remote region of southwest Uganda has demonstrated the feasibility of using a health campaign to rapidly test a community for HIV and simultaneously offer prevention and diagnosis for a variety of other diseases in rural and resource-poor settings of sub-Saharan Africa.
Recent guidelines recommending cholesterol tests for children fail to weigh health benefits against potential harms and costs, according to a new commentary authored by three physician-researchers at UCSF.
An ongoing clinical study in rural Uganda, begun in 2011, suggests that many people infected with HIV/AIDS would take antiretroviral drugs if they were available to them—even before they developed symptoms from the disease.
Researchers from the University of California, San Francisco (UCSF) and Makerere University in Uganda have used hair and blood samples from three-month old infants born to HIV-positive mothers to measure the uninfected babies’ exposure—both in the womb and from breast-feeding—to antiretroviral medications their mothers were taking. The results, they said, are surprising.
The advent of combination antiretroviral therapy in 1996, and patients’ success using the drugs in managing HIV, led to diminished interest in research towards a cure for a number of years.
A rare type of cancer thought to derive from cells in the bile ducts of the liver may actually develop when one type of liver cell morphs into a totally different type, a process scientists used to consider all but impossible. UCSF researchers triggered this kind of cellular transformation—and caused tumors to form in mice—by activating just two genes. Their discovery suggests that drugs that are able to target those genes may provide a way to treat the deadly cancer, known as cholangiocarcinoma. It also shows, yet again, how the process of scientific discovery involves serendipity as well as skill.
The UCSF-affiliated Ernest Gallo Clinic and Research Center has been selected to administer and manage a U.S. Army-funded research program intended to accelerate the discovery and development of new medications to treat alcohol and substance abuse in the context of post-traumatic stress and combat injury.
The ability for substances to pass through the blood-brain barrier is increased after adult stroke, but not after neonatal stroke, according to a new study the UCSF that will be published July 11 in the Journal of Neuroscience.
Cancer patients across the country have a new way to navigate through difficult treatment decisions and communicate better with their doctors. “Open to Options,’’ which recently launched nationally, was developed in conjunction with UCSF to guide patients in making critical health decisions.
People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return—it's a question of when. And for far too many, it happens far too soon.
An investigation led by UCSF has found that the risk of female-to-male HIV transmission is increased three fold for women with bacterial vaginosis, a common disorder in which the normal balance of bacteria in the vagina is disrupted.
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