The UC Davis Department of Obstetrics and Gynecology is recruiting potential participants for a clinical trial of an investigational hormone-free monthly intravaginal method of contraception.
Strong bitterness is the main reason why people all over the world, especially children, avoid taking their medicines, putting their health, and sometimes, their lives at risk. Now, a group of scientists at the Monell Chemical Senses Center identified the first temporary, universal taste blocker that works in people.
Clinicians at Georgetown University’s Lombardi Comprehensive Cancer Center reported promising preliminary findings based on outcomes in the first six patients with metastatic pancreatic cancer enrolled in a phase 2 clinical trial of the experimental drug BXCL701 in combination with the immunotherapy drug pembrolizumab (Keytruda).
The University of Illinois Chicago study will be the first to assess whether the natural product has anti-cancer effects that could benefit patients as they await surgical treatment.
The Icahn School of Medicine at Mount Sinai Health System is spearheading a collaborative effort to investigate dupilumab as a treatment for children with alopecia areata, a disease that causes extensive hair loss.
MD Anderson and Replay today announced that the Food & Drug Administration (FDA) has issued a ‘safe to proceed’ for the Investigational New Drug (IND) application for PRAME TCR/IL-15 NK (SY-307), an engineered T cell receptor natural killer (TCR NK) cell therapy for relapsed/refractory myeloid malignancies.
The Speech Accessibility Project, which aims to make automatic speech recognition technology more accessible to people with speech differences and disabilities, is now sharing some of its voice recordings and related data with universities, nonprofits and companies.
A clinical trial from Keck Medicine of USC aims to provide a surgical solution for patients with a form of advanced pancreatic cancer previously considered inoperable.
The Phase 3 CELLEBRATE trial to test a regenerative stem cell-based therapy in treating patients with stress urinary incontinence is continuing to recruit additional subjects after changing its study protocol to include only patients who have already tried surgery.
Samara Rahman, 74, enrolled in a clinical trial at UCLA Health that was evaluating an “off-the-shelf” vaccine that is given after surgery to prevent or delay the cancer from coming back in high-risk patients.
Clinical studies suggest the Mediterranean diet, and one of its main components, extra virgin olive oil (EVOO), improves cognitive function and slows Alzheimer's disease (AD) progression. Researchers will now investigate whether this is true even for people with a family history of AD and signs of genetic predisposition caused by dysfunction in the APOE gene.
A medication that appeared to stabilize the function and shape of red blood cells in an earlier study for patients with sickle cell disease is now part of a Phase III clinical trial that is open for enrollment at UTHealth Houston.
For years, researchers and clinicians at University of Michigan have sent recycled, or reconditioned, pacemakers to low- and middle-income countries for compassionate use cases in 2010 through the “My Heart Your Heart” program.
Currently, the U-M team is leading an international clinical trial that is testing the impact of sending reconditioned pacemakers abroad for standard use. If successful, the trial could greatly increase access to pacemaker treatment for patients who otherwise would not receive it.
Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center’s ALS Center is the first ALS care provider in the United States to offer patients a new interventional clinical study.
Researchers with Sylvester Comprehensive Cancer Center have received funding to better understand how personalized nutrition and exercise programs can improve quality of life after cancer treatment.
UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.
George T. Grossberg, M.D., and colleagues were instrumental in developing the first and only Food and Drug Administration (FDA) approved treatment for agitation associated with Alzheimer's dementia.
The Speech Accessibility Project is now recruiting U.S. adults with Down syndrome. The project aims to make voice recognition technology more useful for people with diverse speech patterns and different disabilities.
UNC Health is the only academic healthcare system in North Carolina and the South participating in the randomized trial, which aims to assess the safety and efficacy of a combination immunotherapy for newly diagnosed glioblastoma patients.
Chronic inflammation of the skin, or Hidradenitis Suppurativa (HS), disproportionately affects women and people of color. It can be debilitating, negatively impacting suffers’ quality of life, physical function, work productivity, and the social and emotional wellbeing.
Researchers at Saint Louis University (SLU) are enrolling participants in a clinical trial to increase youth sport coaches' knowledge of musculoskeletal injuries and how to prevent them. Principal investigator Oluwatoyosi Owoeye, Ph.D., assistant professor of physical therapy at SLU, says this is the first study of its kind.
Researchers are working to improve outcomes for Black women with breast cancer – including through increased participation in clinical trials, which helps find better ways to prevent, diagnose and treat cancer.
The Trauma and Transfusion Medicine Research Center (TTMRC) in the Department of Surgery at the University of Pittsburgh School of Medicine is launching a $34 million, federally funded clinical trial to simultaneously test multiple interventions for life-threatening bleeding in at least 1,000 traumatically injured children across 20 U.S. pediatric trauma centers.
Researchers from UChicago will lead the next phase of the Illinois Precision Medicine Consortium (IPMC)'s participation in the National Institutes of Health's All of Us Research Program.
The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson’s. Project participant and Parkinson's advocate Ethan Henderson can comment.
Researchers at RUSH are seeking volunteers to explore how a change in diet may improve brain health after a stroke. The study, called NOURISH — short for Nutrition Effects on Brain Outcomes and Recovery in Stroke After Hospitalization — aims to prevent cognitive and memory decline that is common in stroke survivors.
The Food and Drug Administration announced yesterday the approval of HEPZATO Kit to treat ocular melanoma that has spread to the liver. HEPZATO uses a hepatic delivery system to inject the chemotherapy drug melphalan into the liver, a procedure referred to as percutaneous hepatic perfusion (PHP). Moffitt Cancer Center’s Jonathan S. Zager, M.D., was the lead international principal investigator on the multinational FOCUS phase 3 clinical trial to test the procedure, which is manufactured by Delcath Systems, Inc.
A clinical trial evaluating the role of statins in the risk of recurrent intracerebral hemorrhage (ICH) in patients presenting with ICH, has opened for enrollment at UTHealth Houston.
The Project to Accelerate New Treatments for Tuberculosis (PAN-TB) collaboration announced today the start of a phase 2b/c clinical trial, sponsored by the Bill & Melinda Gates Medical Research Institute (Gates MRI).
Following up on positive results from preliminary research, scientists at University of Utah Health are evaluating whether an eight-week program based on positive psychology techniques can improve the mood and well-being of people who have had a stroke and those who care for them.
Two clinical trials that will evaluate drugs, biologics, medical devices, and other therapies for long COVID that are sponsored by the National Institutes of Health (NIH) will launch at UTHealth Houston.
Today, the National Institutes of Health launched and is opening enrollment for phase 2 clinical trials that will evaluate at least four potential treatments for long COVID, with additional clinical trials to test at least seven more treatments expected in the coming months. Treatments will include drugs, biologics, medical devices and other therapies.
Velico Medical has begun a Phase I safety study for their FrontlineODP (OnDemandPlasma) Spray Dried Plasma product in a multi-center, dose escalation clinical trial.
Overlook Medical Center in NJ, is the 1st site in the nation to dose a patient in the Phase IIb RESTORE Trial for newly-diagnosed glioblastoma tumors. Researchers will see whether using NanO2 TM, a drug by NuvOx Pharma to infuse oxygen into hypoxic tissues, can boost traditional radiation and chemo.
A 2022 outbreak of mpox (formerly monkeypox) sickened more than 30,000 people and caused 38 deaths in the United States. It highlighted the lack of an approved vaccine for those under 18 years old.
A new clinical trial run by Howard University, the University of Illinois Chicago and the University of Miami Miller School of Medicine will partner with community organizations and sites to bring life-saving care closer to a highly vulnerable population – Black people with opioid use disorder.
A study involving UCLA Jonsson Comprehensive Cancer Center researchers found when ribociclib, a targeted therapy drug, is added to hormone therapy there are significant survival benefits for patients with early hormone-receptor (HR) positive/HER2 negative breast cancer.
The first successful in-patient trial of liver dialysis* has been completed by researchers from UCL, the Royal Free Hospital, UCL spin-out Yaqrit and their collaborators.
A pneumonia trial – the largest ever led by the University of Bristol – will investigate whether aspirin can reduce the risk of a heart attack or stroke in patients who are admitted to hospital with pneumonia.
The Society for Clinical Trials (SCT) is pleased to announce that the prestigious David Sackett Trial of the Year Award will be presented to The Chronic Hypertension and Pregnancy (CHAP) Trial.
UCLA Health investigators are leading a new, six-city trial of injectable buprenorphine for treatment of methamphetamine use disorder in adults who also use opioids.
UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CART-cell therapy.