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Newswise Special Wire
Tuesday, January 30, 2018

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Newswise Cancer Research Wire for 30-Jan-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Refusing Surgery for Esophageal Cancer May Cause Severe Consequences for Patients

Patients with esophageal cancer who refuse surgery when it is recommended are less likely to survive long term than similar groups of patients who undergo an operation.

– The Society of Thoracic Surgeons

54th Annual Meeting of The Society of Thoracic Surgeons

Embargo expired on 30-Jan-2018 at 10:00 ET

Moffitt Researchers Discover New Approach to Stimulate an Immune Response Against Tumor Cells

New drugs that activate the immune system to target cancer cells have improved the lives of many patients with cancer. However, immunotherapies are not effective in all patients, and the success of these therapies depends on individual patient factor...

– Moffitt Cancer Center

Cancer Cell, Jan-2018

Microcapsules Gain a New Power — Scavenging Reactive Oxygen Species

Stable, biocompatible microcapsules have gained a new power — the ability to scavenge reactive oxygen species. This may aid microcapsule survival in the body as the tiny polymer capsules carry a drug or other biomolecules, or find use in antioxidan...

– University of Alabama at Birmingham

Chemistry of Materials; DMR 1608728; DK099550; 7-12-CD-11; 1-SRA-2015-42-AN

Expert Panel Issues New Guidelines for Lung Cancer Molecular Testing

Experts from three major organizations add ROS1 to list of tests matching lung cancer with targeted treatments.

– University of Colorado Cancer Center

Archives of Pathology & Laboratory Medicine

Interactive Tool Improves Patient Knowledge of Breast Cancer Treatment Options

Breast cancer patients who used an interactive website were more informed about options and felt better prepared to make a treatment choice.

– Michigan Medicine - University of Michigan

Journal of Clinical Oncology; P01 CA163223

Advances in Head and Neck Cancer Research Featured in Upcoming Symposium, News Briefing

Co-sponsors of the 2018 Multidisciplinary Head and Neck Cancers Symposium announced four abstracts that will be highlighted in the meeting's official press program. Researchers will present the findings of these studies in an online news briefing for...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

International Expert at UAMS Myeloma Institute Releases First Book on Castleman Disease

Castleman disease, a rare disorder of the lymph nodes and related tissues, was identified and named more than a half-century ago but, until recently, no one had written a book exclusively about it. Frits van Rhee, M.D., Ph.D., professor of medicin...

Expert Available

– University of Arkansas for Medical Sciences

Cervical Cancer Awareness

While cervical cancer can be deadly, it is preventable. Rutgers Cancer Institute of New Jersey's Dr. Eugenia Girda shares more about screening and the HPV vaccine.

Expert Available

– Rutgers Cancer Institute of New Jersey

A Phenotypic High-Throughput Screen to Identify Modulators that Improve Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity

A phenotypic high-throughput screen to identify modulators that improve mutant cystic fibrosis transmembrane conductance regulator (CFTR) activity is described in the SLAS Discovery February 2018 front cover feature article by Giuliano and colleagues...

– SLAS (Society for Laboratory Automation and Screening)

Journal of Biomolecular Screening; Journal of Laboratory Automation

Short-Course Radiation Treatment Is Safe and Effective for Skin Cancer

A recent Penn State College of Medicine physician’s study review suggests that shorter courses of radiation are preferable to longer ones for older patients receiving treatment for slow-growing skin cancers.

– Penn State College of Medicine

Radiotherapy and Oncology

Study Suggests PD-1 Inhibitors Against Aggressive Pediatric Brain Cancer Subtype

A University of Colorado Cancer Center study published in the journal Pediatric Blood Cancers lays the scientific groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.

– University of Colorado Cancer Center

Pediatric Blood & Cancer

Microbubbles Make Breast Cancer More Susceptible to Radiation Therapy

Bursting oxygen-filled microbubbles in breast cancer makes tumors three times more sensitive to radiation therapy in preliminary tests with animal models of the disease

– Thomas Jefferson University

International Journal of Radiation Oncology•Biology•Physics

Silencing Is Golden: Scientists Image Molecules Vital for Gene Regulation

Lab scientists use cryo-electron microscopy to gain a deeper understanding of the structure of a regulatory complex. Their research could open up new possibilities for cancer therapies.

– Lawrence Berkeley National Laboratory

Science; Nature Structural and Molecular Biology

NUS Researchers Develop Wireless Light Switch for Targeted Cancer Therapy

A team of scientists from the National University of Singapore has developed a way to wirelessly deliver light into deep regions of the body to activate light-sensitive drugs for photodynamic therapy (PDT). This technology could potentially enable PD...

– National University of Singapore

Proceedings of the National Academy of Sciences, 29 Jan-2018

Liver Cancer Screening Rates Must Improve

Patients with cirrhosis should be screened regularly for liver cancer, though few are – in part because busy physicians often don’t order the screening tests, said UT Southwestern oncologists.

– UT Southwestern Medical Center

Decoding the DNA Repair Process

Researchers at The University of Kansas Cancer Center are working to fill the knowledge gap between DNA damage and cancer, including developing approaches to manipulate the DNA damage response to treat and prevent disease. Their research on an integr...

– University of Kansas Cancer Center

Nature Communications, 26th January 2018

Embargo expired on 26-Jan-2018 at 17:05 ET

Major League Coach Tony Beasley Tells His Story of Surviving Colorectal Cancer in New PSA

“See every obstacle as an opportunity in life.” That’s just some of the advice packed into a new campaign by Fight Colorectal Cancer featuring Texas Rangers third-base coach Tony Beasley.

– Fight Colorectal Cancer

Research Test Identifies BRCA2 Gene Mutations That Lead to Breast, Ovarian Cancers

A new test developed by researchers at Mayo Clinic shows which mutations in the BRCA2 gene make women susceptible to developing breast or ovarian cancers. The research behind the test was published today in the American Journal of Human Genetics.

– Mayo Clinic

American Journal of Human Genetics

Embargo expired on 25-Jan-2018 at 12:00 ET

UCLA Study Could Explain Link Between High-Cholesterol Diet and Colon Cancer

UCLA scientists found that boosting mice's cholesterol levels spurred intestinal stem cells to divide more quickly, enabling tumors to form faster. The study identifies a new drug target for colon cancer treatment.

– University of California, Los Angeles (UCLA), Health Sciences

Cell Stem Cell, Jan. 25, 2018

Embargo expired on 25-Jan-2018 at 12:00 ET

Yale Cancer Researchers Propose New Ways to Select Patients for Clinical Trials

Yale Cancer Center investigators have demonstrated in a new study that more sophisticated models to assess patient risk for cancer can result in better clinical trials with more definitive results.

– Yale Cancer Center

JAMA Oncology

Embargo expired on 25-Jan-2018 at 11:00 ET

Light-Triggered Nanoparticles Show Promise Against Metastatic Cancer

A new anti-cancer strategy wields light as a precision weapon. Unlike traditional light therapy — which is limited to the skin and areas accessible with an endoscope — this technique can target and attack cancer cells that have spread deep inside...

– Washington University in St. Louis

Nature Communications


Mayo Clinic的研究人员开发的一项新的测试可以显示BRCA2基因(BRCA2 gene)中的哪些突变会使女性易患乳腺(breast)癌或卵巢(ovarian)癌。 与该测试相关的研究发表在美国人类遗传学杂志上(Ame...

– Mayo Clinic

American Journal of Human Genetics

Examen De Un Estudio Identifica Mutaciones en Gen BRCA2 Que Llevan a Cáncer De Mama Y Ovario

Un nuevo examen desarrollado por los investigadores de Mayo Clinic revela cuáles mutaciones en el gen BRCA2 vuelven a una mujer susceptible al desarrollo de cáncer de mama o de cáncer de ovario. El estudio detrás del examen fue publicado hoy en A...

– Mayo Clinic

American Journal of Human Genetics

Lyosomes and Mitochondria Chat Each Other Up in Cell

CHICAGO - Northwestern Medicine scientists have discovered that two key cellular structures, called mitochondria and lysosomes, come into direct contact with each other in the cell to regulate their respective functions. This rare discovery has impli...

– Northwestern University


Announcing the 2018 SLAS Technology Ten: Translating Life Sciences Innovation

“The 2018 SLAS Technology Ten represent some of the most innovative scientific achievements that were featured in SLAS Technology in the past 12 months,” says Editor-in-Chief Edward Kai-Hua Chow, PhD (National University of Singapore).

– SLAS (Society for Laboratory Automation and Screening)

Study Provides New Guidelines for Assessing Severity of Head and Neck Cancers

Cedars-Sinai investigators have developed a new, more accurate set of guidelines for assessing the severity of head and neck cancers and predicting patient survival. The new guidelines center around counting the number of malignant lymph nodes found ...

– Cedars-Sinai

Journal of Clinical Oncology

Targeting Bladder Cancer’s Achilles Heel: Stem Cells

Two different proteins work separately as well as synergistically to feed a small pool of stem cells that help bladder cancer resist chemotherapy, research led by a Johns Hopkins Kimmel Cancer Center scientist suggests. The finding, published online ...

– Johns Hopkins Medicine

Cancer Research

Researchers Investigate Bioelectricity to Better Understand Breast Cancer

Bioelectric signaling networks relay signals between cells. Current cancer research focuses primarily on biochemical signaling, but bioelectric signals are another communication system that interacts with biochemical messengers.

– West Virginia University

Embargo expired on 23-Jan-2018 at 14:00 ET

Anemia Discovery Offers New Targets to Treat Fatigue That Affects Millions

UVA has discovered an unknown biological process that controls the production of red blood cells, which carry oxygen to the body. The discovery could help doctors develop new treatments for anemia, which affects millions.

– University of Virginia Health System

Journal of Experimental Medicine; R01DK079924; R01DK101550 ; K08HL093355; LLSNIA-8988-15

New Gel Reduces Side Effects of Prostate Cancer Treatment

Radiation therapy is a popular and effective treatment for many men with prostate cancer, and now a temporary gel offers greater protection for organs at risk during treatments.

– Beaumont Health

International Journal of Radiation Oncology

Genetic Lung Disease’s Molecular Roots Identified

People with the rare genetic disease primary ciliary dyskinesia suffer repeated lung infections because they lack functional cilia, hairlike structures that sweep mucus through the airways.  Most people have errors in the molecular motor that powers...

– Washington University in St. Louis

PNAS, Jan-2018; HL128370; CDI-CORE-2015-505; 3770


Huntsman Cancer Institute Selected as a NCI Center for Patient-Derived Model Development

Huntsman Cancer Institute at the University of Utah has been awarded a $2.4 million, two-year grant from the National Cancer Institute to help continue its research in breast cancer researchers will use this new funding to serve as a Breast Cancer Pa...

– Huntsman Cancer Institute at the University of Utah

U54 CA224076

NCCN Imaging Appropriate Use Criteria Endorsed by Intermountain Healthcare and Will be Included in the Intermountain AUC for Lung Cancer

Intermountain Healthcare has endorsed the The National Comprehensive Cancer Network® (NCCN®) Imaging Appropriate Use Criteria (NCCN Imaging AUC™). Intermountain will aggregate the NCCN AUC for lung cancer with its own AUC and utilize the content ...

– National Comprehensive Cancer Network® (NCCN®)

Embargo expired on 25-Jan-2018 at 11:15 ET

Alex Huang, MD, PhD, Receives $450,000 from Pediatric Cancer Research Foundation

Leading cancer researcher, Alex Huang MD, PhD, has received a $450,000 Basic Science grant from Pediatric Cancer Research Foundation to study targeted approaches for effectively eliminating metastatic osteosarcoma.

– Case Western Reserve University

Pediatric Cancer Research Foundation

The Princess Margaret Cancer Foundation hosts 13th Annual Taylor Cup Pond Hockey Tournament

The Princess Margaret Cancer Foundation would like to invite media to attend this year’s Taylor Cup Pond Hockey Championship.

– University Health Network (UHN)

Alexander Khalessi, MD, Named Chair of Neurosurgery Department at UC San Diego Health

After a national search, Alexander Khalessi, MD, has been named chair of the Department of Neurosurgery at UC San Diego Health and chief of the Division of Neurosurgery in the Department of Surgery at University of California San Diego School of Medi...

– University of California San Diego Health

Higher Education Events

UNM Lobo Men’s and Women’s Basketball Celebrate ‘Lobos Love Pink’ Week

The University of New Mexico Men’s and Women’s basketball teams will hold their ‘Lobos Love Pink’ games during the same week to raise awareness for breast cancer and to honor all those who face it. The games also raise awareness for breast ca...

– University of New Mexico Comprehensive Cancer Center





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