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Newswise Special Wire
Tuesday, April 3, 2018

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Newswise Cancer Research Wire for 03-Apr-2018

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Genetic Material Once Considered Junk Actually Could Hold Key to Cancer Drug Response, Mount Sinai Researchers Find

Material left out of common processes for sequencing genetic material in cancer tumors may actually carry important information about why only some people respond to immunotherapy, possibly offering better insight than the type of material that is be...

– Mount Sinai Health System

Cell Reports, Apr-2018; 1545935; K12CA087723-11A1

Embargo expired on 03-Apr-2018 at 12:00 ET

Ionizing Radiation Found to Soften Tumor Cell Microenvironment

Researchers from Vanderbilt aim to unlock how irradiation -- part of radiation therapy in cancer treatment -- might alter the mechanical properties of the microenvironment. The team demonstrated that ionizing radiation can reduce the stiffness of bot...

– American Institute of Physics (AIP)

Embargo expired on 03-Apr-2018 at 11:00 ET

Mathematical Modeling Offers New Way to Understand Variable Responses to Targeted Therapy

Cancer therapies that target a specific protein have improved outcomes for patients. However, many patients eventually develop resistance to these targeted therapies and their cancer comes back. It is believed that differences among tumor cells, or h...

– Moffitt Cancer Center

PLOS Biology

Scientists Discover New Method for Measuring Cellular Age

A team led by scientists at Van Andel Research Institute (VARI) and Cedars-Sinai have developed a straightforward, computational way to measure cellular age, a feat that may lead to better, simpler screening and monitoring methods for cancer and othe...

– Van Andel Research Institute

Nature Genetics

Embargo expired on 02-Apr-2018 at 11:00 ET

Molecular Inhibitors Can Boost Natural Tumor Suppression to Fight Lung Cancer and Mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis. The study, published today in Oncogene, represents significant progress ...

– Sbarro Health Research Organization (SHRO)


Even DNA that Doesn’t Encode Genes Can Drive Cancer

The vast majority of genetic mutations associated with cancer occur in non-coding regions of the genome, yet it’s unclear how they may influence tumor development or growth. Researchers at University of California San Diego School of Medicine and M...

– University of California San Diego Health

Nature Genetics

Potential of Manipulating Gut Microbiome to Boost Efficacy of Cancer Immunotherapies

The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard-to-treat c...

– Perelman School of Medicine at the University of Pennsylvania

Journal of Clinical Investigation Insights

Fred Hutch Tip Sheet - 04/03/18

The Fred Hutch Tip Sheet includes story ideas about: New paths to malaria prevention; proteins involved in muscular dystrophy; pathogen-associated cancers; lung cancer in women who never smoked; financial impact of cancer care; more

– Fred Hutchinson Cancer Research Center

New Non-Invasive Test for Urothelial Cancer Emerging

Urothelial cancers of the bladder and upper urinary tract are among the most common cancers encountered worldwide. Now an international team of cancer researchers have developed a highly sensitive and specific non-invasive test as a biomarker for ear...

– Stony Brook Medicine


Neurocognitive Risk May Begin Before Treatment for Young Leukemia Patients

Chemotherapy agents have been associated with neurocognitive side effects in young leukemia survivors. Now St. Jude Children’s Research Hospital scientists have evidence the disease and genetics might also play a role.

– St. Jude Children's Research Hospital

JAMA Oncology, March 2018

Embargo expired on 29-Mar-2018 at 11:00 ET

Slow, Steady Waves Keep Brain Humming

Very slow brain waves, long considered an artifact of brain scanning techniques, may be more important than anyone had realized. Researchers at Washington University School of Medicine in St. Louis have found that very slow waves are directly linked ...

– Washington University in St. Louis

Neuron, Mar-2018; R01 NS099429 ; F30MH106253; NS080675; R01NS084028; R01NS085419; R01NS094692; F31NS089135; MH102471; R01 NS078223

Embargo expired on 29-Mar-2018 at 12:00 ET

Topical Solution May Be Less Toxic Option for Patients with Noncancerous Skin Growth

A team of researchers at the GW School of Medicine and Health Sciences compared the toxicological impact of cryosurgery with an FDA-approved topical 40 percent hydrogen peroxide solution (A-101) for the treatment of seborrheic keratosis, in human ski...

– George Washington University

Journal of the American Academy of Dermatology

Breast Cancers Detected at Smaller Size in Women with Implants

Breast augmentation with implants does not interfere with the ability to detect later breast cancers—in fact, cancers may be detected at a smaller size in breasts with implants, according to a study in the April issue of Plastic and Reconstructive ...

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Plastic and Reconstructive Surgery

Pediatric Cancer Drug Shows 93 Percent Response Rate

A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern’s Simmons Cancer Center announced.

– UT Southwestern Medical Center

The Lancet Oncology

Queen’s University Belfast First to Transform the Way Discovery is Translated into Patient Care

For every 100 occasions that scientists across the world announce a discovery that can have significant impact in patient care, less than 1 makes it into a product that is eventually useful for patients in our healthcare service. The £10million Que...

– Queen's University Belfast

Healthcare Experts Tackle Tough Challenges at Fortune Brainstorm HEALTH 2018

On March 19-20 in California, the third Fortune Brainstorm HEALTH conference brought together renowned leaders from healthcare and related industries to provide insight into today’s most pressing challenges as well as how we might solve them.

– Cancer Research Institute

Surgeons Transform Static ‘Mona Lisa’ Smiles to Joyous Ones

By modifying a muscle transplant operation, Johns Hopkins surgeons report they are able to restore authentic facial expressions of joy -- wide and even smiles -- to selected patients with one-sided facial muscle paralysis due to birth defects, stroke...

– Johns Hopkins Medicine

JAMA Facial Plastic Surgery

UTSW Study Helps Explain Launch Switch for Most Common Malignant Pediatric Brain Tumor

By detailing the mechanisms underlying the development of medulloblastoma tumors, these findings could lead to new treatments, noted Dr. Mukhopadhyay, a W.W. Caruth, Jr. Scholar in Biomedical Research.

– UT Southwestern Medical Center

Cell Reports

A Closer Look at the Association Between Breast Implants and an Uncommon Form of Cancer


Expert Available

– Rutgers Cancer Institute of New Jersey

The Clouds of Spaghetti That Keep DNA Data Safe

Cells can avoid “data breaches” when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of...

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Biological Chemistry, March 23

Are You More Likely to Get Sick When The Seasons Change? Here's What Experts Say

Research suggests the common cold thrives in cooler temperatures. One recent study from Yale University found a seven-degree drop in ambient temperature can mess with your body’s ability to stop cold viruses from proliferating.

– Yale Cancer Center


Time for Oral Cancer Screening: Young and Healthy Need Screening Too

Did you know the quickest growing segment of the oral cancer population is young, healthy, non-smokers? Commonly associated with tobacco use, oral cancer can strike anyone. In younger populations the incidence of this form of cancer is on the rise in...

– Stony Brook Medicine

Policy and Public Affairs

Two Leading Oncologists Co-Author Paper on Nuclear Terrorism

Special report details serious concerns that medical community would be able to do much, if anything, to assist people in event of major nuclear event. Prevention is best option as well as carefully conceived, long-term plan within the public educati...

– University of Nebraska Medical Center (UNMC)

New England Journal of Medicine, March 29, 2018

Embargo expired on 28-Mar-2018 at 17:00 ET


Penn’s E. John Wherry Receives Stand Up to Cancer’s Innovation in Collaboration Award

E. John Wherry, PhD, co-leader of the Abramson Cancer Center’s Immunobiology Program and director of the Institute for Immunology at the University of Pennsylvania, has received a Phillip A. Sharp Innovation in Collaboration Award from Stand Up To ...

– Perelman School of Medicine at the University of Pennsylvania

Pediatric Cancer Research at Case Western Reserve University and UH Rainbow Babies & Children’s Hospital Gets a Boost from St. Baldrick’s Foundation

Leading cancer researchers, Alex Huang MD, PhD, and Yamilet Huerta, MD have been awarded $186,405 in grants from the St. Baldrick’s Foundation to conduct pediatric cancer research.

– Case Western Reserve University

St. Baldrick's Foundation

Penn State Health and Penn State College of Medicine Elevate Radiation Oncology to Department Status

Penn State College of Medicine has created a new Department of Radiation Oncology and named Dr. Rickhesvar Mahraj, professor of radiology and pediatrics, its interim chair.

– Penn State Health Milton S. Hershey Medical Center

Living Beyond Breast Cancer to Host 12th Annual National Metastatic Breast Cancer Conference April 20–22 in Philadelphia

The 2018 Conference on Metastatic Breast Cancer, hosted by Living Beyond Breast Cancer (LBBC.ORG) will mark its 12th year, featuring sessions on leading-edge treatments as well as how to manage the physical, social, emotional and financial impacts of...

– Living Beyond Breast Cancer

National Comprehensive Cancer Network Honors Key Contributors to the Improvement of Global Cancer Care and Dedication to the NCCN Mission

NCCN presented awards during the NCCN 23rd Annual Conference to Crystal Denlinger, MD, Abdul-Rahman Jazieh, MD, MPH, Warren Smedley, MSHA, Ronald Walters, MD, MBA, MHA, MS, and Kristin Kline Hasson.

– National Comprehensive Cancer Network® (NCCN®)

With $150M Gift, Rogels Will Help U-M Cancer Center Transform Cancer Research, Care

Richard and Susan Rogel are committing $150 million to the University of Michigan Comprehensive Cancer Center to support innovative cancer research and develop the next generation of cancer research pioneers. The cancer center will be renamed the Rog...

– Michigan Medicine - University of Michigan

Get Your Colour on, Canada!

The Princess Margaret Cancer Foundation will announce the launch of Colour Your Hair to Conquer Cancer presented by Trade Secrets.

– University Health Network (UHN)

CPRIT Awards UT Southwestern Investigators $27 Million for Cancer Prevention and Research

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded UT Southwestern researchers more than $27 million, including nearly $3 million for two key cancer screening programs in underserved areas.

– UT Southwestern Medical Center

CPRIT Awards UT Southwestern Investigators $16 Million for Cancer Therapy Research

More than a dozen UT Southwestern Simmons Cancer Center researchers received awards from the Cancer Prevention and Research Institute of Texas (CPRIT) for research into breast, prostate, brain, kidney, liver, and pediatric cancers.

– UT Southwestern Medical Center

Rutgers Cancer Institute of New Jersey and RWJBarnabas Health Leader Named to NJBIZ Power 100 List

Rutgers Cancer Institute of New Jersey Director Steven K. Libutti, MD, FACS, who is also senior vice president of oncology services at RWJBarnabas Health and vice chancellor for cancer programs for Rutgers Biomedical and Health Sciences, has been nam...

– Rutgers Cancer Institute of New Jersey

Expert Pitch

Coffee and Cancer: Epidemiologist Available

– University of California, Los Angeles (UCLA), Health Sciences





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