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Wednesday, January 17, 2018

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Medical News

A Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule Inhibitors of CD73 with Diverse Inhibition Modalities

A new original research article in SLAS Discovery presents a fast, sensitive, and robust methodology for screening small molecule inhibitors against CD73/Ecto-5’-Nucleotidase, a promising target for developing anti-cancer drugs.

– SLAS (Society for Laboratory Automation and Screening)

SLAS Discovery

Embargo expired on 17-Jan-2018 at 02:00 ET

Mount Sinai Researchers Identify Protein Involved in Cocaine Addiction

Mount Sinai researchers have identified a protein produced by the immune system—granulocyte-colony stimulating factor (G-CSF)—that could be responsible for the development of cocaine addiction.

– Mount Sinai Health System

Nature Communications

Embargo expired on 16-Jan-2018 at 11:00 ET

Who Might Benefit From Immunotherapy? New Study Suggests Possible Marker

New research finds that PDL-1 expressed in antigen presenting cells – macrophages and dendritic cells found in the tumor microenvironment and in the nearby lymph nodes -- is a better indicator than PDL-1 in the tumor of who will respond to immunoth...

– Michigan Medicine - University of Michigan

Journal of Clinical Investigation; CA123088; CA099985; CA156685; CA171306; CA190176; CA193136; CA211016; 5P30CA46592

Embargo expired on 16-Jan-2018 at 16:00 ET

Previous Influenza Virus Exposures Enhance Susceptibility in Another Influenza Pandemic

New data analysis suggests that people born at the time of the 1957 H2N2 or Asian Flu pandemic were at a higher risk of dying during the 2009 H1N1 Swine Flu pandemic as well as the resurgent H1N1 outbreak in 2013-2014. And it is not the first time th...

– McMaster University


Embargo expired on 16-Jan-2018 at 10:00 ET

Study Says Some Nursing Homes Gaming the System to Improve Their Medicare Star Ratings

A new study of nursing homes in California, the nation’s largest system, found that some nursing homes inflate their self-assessment reporting to improve their score in the Five-Star Quality Rating System employed by Medicare to help consumers.

– Florida Atlantic University

Production and Operations Management,

Canine Distemper Confirmed in Far Eastern Leopard, World’s Most Endangered Big Cat

The Far Eastern or Amur leopard (Panthera pardus orientalis) is already among the rarest of the world’s big cats, but new research reveals that it faces yet another threat: infection with canine distemper virus (CDV).

– Wildlife Conservation Society

Journal of Wildlife Diseases

UF Study: Aged Garlic Extract May Help Obese Adults Combat Inflammation

Obesity has grown into a serious health issue worldwide, especially in Western countries. In the U.S., more than one-third of adults are obese, according to the Centers for Disease Control and Prevention.

– University of Florida Institute of Food and Agricultural Sciences

Clinical Nutrition ESPEN

Pediatric Physician-Scientists Struggle for Funding

A new, multicenter study that included Washington University School of Medicine in St. Louis has found that most NIH grants awarded to researchers in pediatrics during the past five years have been limited to physicians in senior positions at a small...

– Washington University in St. Louis

JAMA Pediatrics

Squirtable Surgical Glue Could Transform Surgeries and Save Lives

Sutures and staples can be inadequate in complex surgeries and cannot make an air-tight or liquid-tight seal on a lung or artery wound or incision. Now researchers have created a surgical glue that sets to form an elastic air-tight or liquid-tight se...

– National Institute of Biomedical Imaging and Bioengineering

Sci Transl Med, Oct-2017; EB023052, EB022043, EB021148, EB014283

More Evidence of Link Between Severe Gum Disease and Cancer Risk

A new study adds to accumulating research that gum disease is associated with some cancer risk, reporting a 24 percent increase in the risk of cancer among participants with severe periodontitis. The highest risk was observed in cases of lung cancer,...

– Tufts University

JNCI, Jan 2018; R01CA166150; P30CA00697; P30CA006973, U01CA164975, HHSN268201700001I, HHSN268201700003I, HHSN268201700005I, HHSN268201700004

In Chronic Disease Care, Family Helpers Are Key, But Feel Left Out

People with diabetes, heart failure and other chronic diseases often live independent lives, without a traditional caregiver. But many have a family member or friend who plays a key supporting role in their health care.

– Michigan Medicine - University of Michigan

Fam Syst Health. 2017 Dec; 35(4): 463–473. doi: 10.1037/fsh0000293

Evidence Supports 'Weekend Effect' for Mortality after Surgery

As for other types of medical care, surgery appears to be prone to a significant "weekend effect"— with higher odds of death when surgery is performed during or one or two days before the weekend, suggests a report in the February issue of Medical ...

– Wolters Kluwer Health: Lippincott Williams and Wilkins

Medical Care

Older Adults Are Increasingly Identifying - But Still Likely Underestimating - Cognitive Impairment in Their Families

An increasing number of older adults are reporting cognitive impairment in their families over the past two decades, according to a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University's Brody School of Medi...

– New York University

Preventing Chronic Disease, Jan 2018

Researchers Identify New Way to Unmask Melanoma Cells to the Immune System

A research team at the Duke Cancer Institute has found a new way to keep the immune system engaged, and is planning to test the approach in a phase 1 clinical trial.

– Duke Health

Immunity; 1K08CA191063-01A1

Memory Loss From West Nile Virus May Be Preventable

People who survive brain infection with West Nile virus can have neurological problems long after the virus is gone. A new study in mice suggests that such ongoing problems may be due to unresolved inflammation that hinders the brain's ability to rep...

– Washington University in St. Louis

Nature Immunology, Jan-2018; U19 AI083019; R01 NS052632; HDTRA11510032; P30AR048335

A ‘Touching Sight’: How Babies’ Brains Process Touch Builds Foundations for Learning

A new study from the University of Washington Institute for Learning & Brain Sciences (I-LABS) provides one of the first looks inside the infant’s brain to show where the sense of touch is processed — not just when a baby feels a touch to the han...

– University of Washington

Developmental Science

Having a Pharmacist at Stroke Patient's Bedside Speeds Administration of Critical Drug

In treating stroke patients, every minute counts. A drug called rtPA sometimes can stop a stroke in its tracks. Now a Loyola Medicine study has found that having a pharmacist at the patient's bedside can reduce the time it takes to administer rtPA by...

– Loyola University Health System

Annals of Pharmacotherapy

Bariatric Surgery Prolongs Lifespan in Obese

Obese, middle-age men and women who had bariatric surgery have half the death rate of those who had traditional medical treatment over a 10-year period, reports a study that answers questions about the long-term risk of the surgery. 

– Northwestern University


Study Advances Gene Therapy for Glaucoma

In a study published today in the scientific journal Investigative Ophthalmology and Visual Science, Kaufman and Curtis Brandt, a fellow professor of ophthalmology and visual sciences at UW-Madison, showed an improved tactic for delivering new genes ...

– University of Wisconsin-Madison

Investigative Ophthalmology and Visual Science

LJI Researchers Discover Key Driver of Atopic Dermatitis

La Jolla Institute scientists demonstrate that LIGHT, a member of the tumor necrosis factor (TNF) super family, directly controls the hyperproliferation of keratinocytes as well as the expression of periostin, a protein that contributes to the clinic...

– La Jolla Institute for Allergy and Immunology

Journal of Experimental Medicine; AI070535; AI100905; AI061516; DK082249

Could an Athlete’s Own Stem Cells Stop Arthritis Development After an ACL Tear?

Long-term consequences can happen years after an ACL injury. One Michigan Medicine researcher is investigating new therapies that could minimize those unwanted effects.

– Michigan Medicine - University of Michigan

Smartphone App Now Recognizes FASD Thanks to MMI Geneticist

With a smartphone and an app, qualified health care professionals can now diagnose fetal alcohol spectrum disorders (FASD) in their office thanks to a suggestion from Omar Rahman, M.D.

– University of Nebraska Medical Center (UNMC)


AACC Releases Practice Guidelines for Using Laboratory Drug Tests to Combat Opioid Addiction, Overdoses

WASHINGTON – AACC has issued a new guideline detailing how healthcare providers can use laboratory tests to manage treatment of pain and prevent prescription drug overdoses. Especially relevant in light of the worsening opioid epidemic, the guideli...

– American Association for Clinical Chemistry (AACC)

Want Romance This Valentine's Day? Help Your Sweetie Avoid Allergy and Asthma Triggers

Romance is the name of the game on Valentine’s Day, and keeping sneezing, wheezing and watery eyes out of the mix helps put everyone more in the mood for love. Here are five tips from ACAAI to help make your Valentine’s Day special.

– American College of Allergy, Asthma and Immunology (ACAAI)

UNC Expert Publishes Commentary About Recent Change in Donor Lung Allocation Policy

Dr. Thomas Egan of the University of North Carolina School of Medicine says that a recent change in donor lung allocation policy was long overdue. However, because the change happened over the Thanksgiving holiday weekend in response to litigation, i...

Expert Available

– University of North Carolina Health Care System

Gregory Liguori to Receive ASRA's 2018 Distinguished Service Award

Gregory A. Liguori, MD, of the Hospital for Special Surgery (HSS) and Weill Cornell Medical College has been selected to receive ASRA’s 2018 Distinguished Service Award at the 2018 World Congress on Regional Anesthesia & Pain Medicine in New York C...

– American Society of Regional Anesthesia and Pain Medicine (ASRA)

Rutgers Names New Director for Institute for Health, Health Care Policy and Aging Research

XinQi Dong, the inaugural Henry Rutgers Professor of Population Health Sciences, is an international advocate for advancing population health issues in under-represented communities

– Rutgers University

Journal of the American Academy of Dermatology Names New Editor

Board-certified dermatologist Dirk M. Elston, MD, FAAD, the current deputy editor of the Journal of the American Academy of Dermatology will step into his new role in July 2018, succeeding board-certified dermatologist Bruce H. Thiers, MD, FAAD, who ...

– American Academy of Dermatology

Journal of the American Academy of Dermatology

Olin College Team Takes Home Prize in "Arc Tank" Competition

Olin College of Engineering students was awarded for their efforts in developing a wheelchair attachment to streamline the ability for one to complete routine tasks.

– Franklin W. Olin College of Engineering

Elevating Patient Care: Penn Medicine Orthopaedics and Princeton Orthopedic Associates Forge Strategic Partnership

Penn Orthopaedics and Princeton Orthopedic Associates have announced a new strategic alliance in an effort to enhance and continue to improve orthopaedic care to patients in New Jersey and Pennsylvania. As part of the Penn Medicine Orthopaedic Specia...

– Perelman School of Medicine at the University of Pennsylvania

Temple University Hospital Ranked #1 in the Nation for Lung Transplant Volume in 2017

Temple University Hospital (TUH) performed 131 lung transplants in calendar year 2017, making it the number 1 volume program in the nation according to data just released by the United Network for Organ Sharing (UNOS).

– Temple University

Hal Skopicki Appointed Chief of Cardiology in the Department of Medicine and Deputy Director of Operations in the Stony Brook University Heart Institute

Hal Skopicki, MD, PhD, has been appointed Chief of Cardiology in the Department of Medicine and Deputy Director of Operations in the Stony Brook University Heart Institute. He is a renowned heart failure specialist, who has led the major effort in ad...

– Stony Brook Medicine

Families Who Adopt Receive Specialized Medical Care From Montefiore

Parents of adopted children can now consult with a nationally recognized expert in adoption medicine at the Children’s Hospital at Montefiore

– Montefiore Health System

NIH Invests in Collaborative Research to Understand Mechanisms Controlling Cell Division

A three-year, $675,000 grant from the National Institutes of Health (NIH) to understand cell-size control in the unicellular green alga Chlamydomonas reinhardtii.

– Donald Danforth Plant Science Center


Science News

X-Rays Reveal ‘Handedness’ in Swirling Electric Vortices

Scientists used spiraling X-rays at Berkeley Lab to observe, for the first time, a property that gives left- or right-handedness to swirling electric patterns – dubbed polar vortices – in a layered material called a superlattice.

– Lawrence Berkeley National Laboratory

Proceedings of the National Academy of Sciences, Jan. 16, 2018

Embargo expired on 16-Jan-2018 at 12:00 ET

New “Buck” Naked Barley: Food, Feed, Brew

Researchers are giving an ancient grain a new life: "Buck" barley is naked, but not in an indecent way. Naked barley does not require pearling, allowing it to hold onto the bran and whole grain status.

– Crop Science Society of America (CSSA)

Journal of Plant Registrations, October 26, 2017

Remotely Predicting Leaf Age in Tropical Forests

New approach offers data across species, sites, and canopies, providing insights into carbon uptake by forests.

– Department of Energy, Office of Science

New Phytologist 214(3), 1033-1048 (2016). [DOI: 10.1111/nph.10451]

Pharmaceuticals and Other Emerging Contaminants Force Fish to Work Harder to Survive

Pharmaceuticals and other man-made contaminants are forcing fish that live downstream from a typical sewage treatment plant to work at least 30 per cent harder just to survive, McMaster researchers have found.

– McMaster University

Environmental Science and Technology

University of Arkansas Scientists Digitally Preserve Important Arkansas Dinosaur Tracks

University of Arkansas researchers used LiDAR imaging to digitally preserve and study important dinosaur tracks.

– University of Arkansas, Fayetteville

PLOS One, Jan. 2 2018

Researchers Devise Decoy Molecule to Block Pain Where It Starts

Dr. Zachary Campbell, who researches pain on the molecular level at the University of Texas at Dallas, recently published a study that describes a new method of reducing pain-associated behaviors with RNA-based medicine, creating a new class of decoy...

– University of Texas at Dallas

Nature Communications, Jan 2, 2018

STUDY: High Tolerance for Wildlife Exists Around Indian Reserves Despite Continued Losses

A new study from WCS (Wildlife Conservation Society), Duke University, and the Centre for Wildlife Studies in India finds that communities living near wildlife reserves in Rajasthan, India, show a high tolerance for wildlife. This is despite them hav...

– Wildlife Conservation Society

Hügelkultur: The Mound Method for Home Gardeners

A bedding system new to Texas – hügelkultur – is trending among home gardeners looking for low-maintenance ways to grow flowers, fruits and vegetables, said Texas A&M AgriLife Extension Service horticulturist Dr. Joe Masabni.

– Texas A&M AgriLife

Power Hour

Argonne’s Education department partnered with the U.S. Department of Energy’s Fermi National Accelerator Laboratory and the University of Chicago and sent 50 scientists to Chicago area schools in December as part of the global Hour of Code.

– Argonne National Laboratory

North Dakota State University Joins Two National Distributed Computing Groups

The NDSU Center for Computationally Assisted Science and Technology (CCAST) joins OSG (Open Science Grid) and XSEDE (Extreme Science and Engineering Discovery Environment).

– North Dakota State University

AANEM Foundation Offers Clinical Research Fellowship on the Neurological Application of Neurotoxins

The AANEM Foundation's 1-year fellowship award supports clinical research training to provide insights and answers about the safety and effectiveness of the neurological application of neurotoxins. Apply for the AANEM Foundation's Clinical Research F...

– American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)

Penn State Aerospace Engineer Receives AFOSR Funding to Investigate Overtrust with Autonomous Vehicles

Overtrust frequently occurs with autonomous vehicles and robots—and it can have serious physical, and even fatal, consequences for humans in both the military and society, but Alan Wagner, assistant professor of aerospace engineering at Penn State,...

– Penn State College of Engineering

Lifestyle & Social Sciences

Changing the Lens on Poverty Research

Poverty statistics have never told the complete story, but new research from Georgia Tech economist Shatakshee Dhongde is pioneering a new approach for measuring deprivation among the elderly

– Georgia Institute of Technology

Measuring Multidimensional Poverty and Deprivation: Incidence and Determinants in Developed Countries

includes video

Task Interrupted: A Plan for Returning Helps You Move On

Get interrupted at work much? Making a quick plan for returning to and completing the task you're leaving will help you focus better on the interrupting work, according to new research from the University of Washington.

– University of Washington

Organization Science

Want People to Work Together? Familiarity, Ability to Pick Partners Could Be Key

The key to getting people to work together effectively could be giving them the flexibility to choose their collaborators and the comfort of working with established contacts, new research suggests.

– Ohio State University

Proceedings of the National Academy of Sciences

Conservation Mind Game

A new study led by Kathryn Caldwell, an assistant professor of psychology at Ithaca College, demonstrates that homeowners can be encouraged to make changes to their energy use with a simple education plan and some helpful tricks from the world of soc...

– Ithaca College

Tracking the Impact of Early Abuse and Neglect

Maltreatment experienced before age 5 can have negative effects that continue to be seen nearly three decades later, according to a new study led by Lee Raby, an assistant professor of psychology at the University of Utah.

– University of Utah

Child Development; R01 AG039453

“Fresno State Is an Important Part of Our Community; It’s Where Our Future Community Leaders Are Being Formed”

Kim Ruiz Beck knew taking her family’s third-generation business to the next level meant she would need a college degree. The education she obtained at Fresno State allowed her to reconstruct the direction of the multi-million dollar company.

– California State University (CSU) Chancellor's Office

Johns Hopkins School of Nursing’s Sarah Szanton Named Edge Runner

Johns Hopkins School of Nursing Professor Sarah L. Szanton, PhD, ANP, FAAN, has been named an American Academy of Nursing Edge Runner for her Community Aging in Place: Advancing Better Living for Elders (CAPABLE) intervention. The honor recognizes nu...

– Johns Hopkins School of Nursing

Olin College Professor Awarded One of First NSF Grants to Enhance STEM Education at Hispanic-Serving Institutions

The National Science Foundation awarded Olin College Assistant Professor of Systems Design and Engineering Dr. Alexandra Coso Strong a collaborative grant to co-create a series of traveling workshops.

– Franklin W. Olin College of Engineering

New Academic and Residential Complex Breaks Ground at UIC

With enrollment hitting record-setting levels at the University of Illinois at Chicago this fall and projected numbers of new students climbing by as many as 10,000 over the next decade, a new “living-learning” community will be built to provide ...

– University of Illinois at Chicago

Business News

DHS S&T and Israeli Partners Call for Proposals on Advanced First Responder Technologies

Applications are now being accepted for the NextGen First Responder Technologies solicitation, an opportunity for a maximum conditional grant of up to $1 million, jointly funded by DHS S&T and the Israel Ministry of Public Security (MOPS).

– Homeland Security's Science & Technology Directorate

Gonzaga Launches Rebuilt Website, First-Ever Intranet

SPOKANE, Wash. – Gonzaga University recently unveiled a completely rebuilt public website,, featuring an abundance of new features and content, as well as the University’s first intranet, called myGU. Developed with input from u...

– Gonzaga University





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