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Newswise Daily Wire
Wednesday, February 14, 2018

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Medical News

Researchers Successfully Reverse Alzheimer’s Disease in Mouse Model

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer’s disease, thereby improv...

– The Rockefeller University Press

Journal of Experimental Medicine, March 5, 2018; NS074256; AG025493; AG046929; NM103942

Embargo expired on 14-Feb-2018 at 09:00 ET

Analysis: Female Drivers Convicted for Driving Under the Influence of Alcohol

Women have become increasingly involved in drunk driving and fatal crashes. However, much of the research on drunk driving has been conducted using predominantly male samples. Little is known about the life context, psychiatric histories, and family ...

– Research Society on Alcoholism

Alcoholism: Clinical and Experimental Research

Embargo expired on 13-Feb-2018 at 10:00 ET

Study Maps Molecular Mechanisms Crucial for New Approach to Heart Disease Therapy

In this study, published in Cell Reports, two labs at UNC and a group at Princeton University reprogrammed ordinary cells called fibroblasts into new and healthy heart muscle cells, and recorded changes that appear to be necessary for this reprogramm...

– University of North Carolina Health Care System

Cell Reports

Embargo expired on 13-Feb-2018 at 12:00 ET

Phase II Trial Demonstrates Activity of Durvalumab in Patients with Recurrent or Metastatic Head and Neck Cancer

Analysis of the phase II CONDOR trial indicates that the immune checkpoint inhibitor durvalumab is tolerable among heavily pre-treated patients with recurrent or metastatic head and neck cancer and has the potential to slow growth in tumors with low ...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 12:00 ET

Nivolumab Immunotherapy Safe and Feasible During Chemoradiation for Advanced Head and Neck Cancer

Analysis of a clinical trial, RTOG Foundation 3504, finds that nivolumab immunotherapy can be administered safely in conjunction with radiation therapy and chemotherapy for patients with newly diagnosed local-regionally advanced head and neck cancers...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 12:00 ET

Lower-Dose Radiation Therapy Effective and Safe for HPV-Related Head and Neck Cancer After Induction Chemotherapy, Trial Finds

Results of the phase II OPTIMA clinical trial indicate that patients with head and neck cancers associated with the human papillomavirus (HPV), including those with advanced nodal disease, can receive substantially lower radiation doses safely and ef...

– American Society for Radiation Oncology (ASTRO)

Multidisc Head and Neck Cancers Symposium, Feb-2018

Embargo expired on 13-Feb-2018 at 12:00 ET

Alternative MRI Contrast Agent Performs Well in NIH Study

NIH-supported researchers at Massachusetts General Hospital are studying an alternative to current contrast agents used for magnetic resonance imaging. In a recent study, they showed that the experimental alternative, which is a manganese-based compo...

– National Institute of Biomedical Imaging and Bioengineering

OD010650; Radiology, Nov. 15, 2017; EB009062; EB022804; RR023385; HL128899; HL119145

Everyday Activities Associated with More Gray Matter in Brains of Older Adults

Higher levels of lifestyle physical activity – such as house cleaning, walking a dog and gardening, as well as exercise – are associated with more gray matter in the brains of older adults, according to a study by researchers at Rush University M...

– Rush University Medical Center

Journal of Gerontology: Psychological Sciences

Palm Oil in Your Valentine's Chocolate?

A diet high in saturated fat causes, in addition to obesity and metabolic changes associated with a prediabetic state, anxiodepressive and compulsive behaviors. All of these effects were shown to be tied to inflammation in the nucleus accumbens, reve...

– Centre hospitalier de l'Université de Montréal (CHUM)

Molecular Metabolism

NIH Funding Fewer Clinical Trials, Study Suggests

The number of clinical trials funded by the National Institutes of Health has declined since 2005, according to a new study by researchers at the Johns Hopkins Bloomberg School of Public Health. During the same period, average trial sizes were observ...

– Johns Hopkins Bloomberg School of Public Health

Clinical Trials

Understanding a Fly’s Body Temperature May Help People Sleep Better

In findings that one day may help people sleep better, scientists have uncovered the first molecular evidence that two anciently conserved proteins in the brains of insects and mammals share a common biological ancestry as regulators of body temperat...

– Cincinnati Children's Hospital Medical Center

Genes & Develpment, Feb-2018

Investigators Highlight Potential of Exercise in Addressing Substance Abuse in Teens

Exercise has numerous, well-documented health benefits. Could it also play a role in preventing and reducing substance misuse and abuse in adolescents? This is the intriguing question that a team of investigators from Case Western Reserve University ...

– Case Western Reserve University

Birth Defects Research; NIH

Scientists Create Most Sophisticated Human Liver Model Yet

Scientists have developed the most sophisticated mini-livers to date. These organoids can potentially help scientists better understand certain congenital liver diseases as well as speed up efforts to create liver tissue in the lab for transplantatio...

– Wake Forest Baptist Medical Center


Cabozantinib Shows Promise as First Line Treatment for Differentiated Thyroid Cancer

A kinase inhibitor called cabozantinib could be a viable therapy option for patients with metastatic, radioactive iodine-resistant thyroid cancer. In a trial initiated and led by the Abramson Cancer Center and the Perelman School of Medicine at the U...

– Perelman School of Medicine at the University of Pennsylvania

2018 Multidisciplinary Head and Neck Cancers Symposium

Scientists Identify Immune Cascade that Fuels Complications, Tissue Damage in Chlamydia Infections

Research in mice pinpoints immune mechanism behind tissue damage and complications of chlamydia infection, the most common sexually transmitted disease in the United States. Separate immune mechanisms drive bacterial clearance versus immune-mediat...

– Harvard Medical School


What Is a ‘Normal’ Blood Pressure Response During Exercise Testing?

New data from the University of Illinois at Chicago suggest that the guidelines used to evaluate an individual’s peak blood pressure response during cardiopulmonary exercise testing, which were last updated in 1996 and help doctors screen for hyper...

– University of Illinois at Chicago


Brain Imaging Helps Redefine Intelligence

NYU Langone study offers the first solid evidence that functional MRI scans of brain entropy are a new means to understanding human intelligence.

– NYU Langone Health


A Synthetic Cell That Produces Anti-Cancer Drugs Within a Tumor

Researchers have successfully treated a cancerous tumor using a “nano-factory” – a synthetic cell that produces anti-cancer proteins within the tumor tissue. The synthetic cell could one day be an important part in the personalized medicine tre...

– American Technion Society

Advanced Healthcare Materials

Newly Discovered Gene May Protect Against Heart Disease

Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels.

– University of California, Los Angeles (UCLA), Health Sciences

Nature Medicine, Feb-2018

Cuando el cuerpo ataca al cerebro: El sistema inmunitario generalmente es el culpable de la encefalitis, descubre estudio

La encefalitis causada por el ataque del sistema inmunitario al cerebro tiene una frecuencia similar a la de la encefalitis producto de infecciones, informan los investigadores de Mayo Clinic en los Anales de Neurología.

– Mayo Clinic

Anales de Neurología

Heroin Vaccine Blocks Lethal Overdose

Scientists at The Scripps Research Institute (TSRI) have achieved a major milestone toward designing a safe and effective vaccine to both treat heroin addiction and block lethal overdose of the drug.

– Scripps Research Institute

Molecular Pharmaceutics; UH3DA041146; F32AI126628; F32DA043323; R42DA040422; R44AI094770

Circulating Lipids Play Roles in Many Diseases

Cholesterol in muscular dystrophy; synergy between alcohol and hepatitis in cholesterol levels; bacterial lipids in healthy arteries.

– American Society for Biochemistry and Molecular Biology (ASBMB)

Journal of Lipid Research; Journal of Lipid Research; Journal of Lipid Research

A Little Preparation Means Sending Your Allergic Camper Off with Confidence This Summer

5 tips from the American College of Allergy, Asthma and Immunology for parents who’d like to send their child with allergies or asthma to summer camp, and still keep them safe.

– American College of Allergy, Asthma and Immunology (ACAAI)

Tips for Men: How to Shave

There is no shortage of men’s razors and other shaving tools on the market, but do any of them offer the perfect shave? According to dermatologists from the American Academy of Dermatology, it’s less about which tools you use, and more about your...

– American Academy of Dermatology

includes video

Statement from the American Pain Society: McCaskill Report on Pharma Company Financial Support for Pain Organizations

McCaskill Report on Pharma Company Financial Support for Pain Organizations

– American Pain Society

Best of Meeting Abstracts Announced for Historic World Congress on Regional Anesthesia and Pain Medicine

Hip fracture, general vs regional, spine surgery among the topics of Best of Meeting Abstracts selected for special presentation at ASRA's 2018 World Congress on Regional Anesthesia and Pain Medicine

– American Society of Regional Anesthesia and Pain Medicine (ASRA)

FAU Approved for First Fellowship in Cardiology

Just in time for Valentine’s Day and American Heart Month, FAU's College of Medicine has received initial accreditation from the national Accreditation Council for Graduate Medical Education for its first University-sponsored fellowship. The FAU Ca...

– Florida Atlantic University

Seattle Children’s Receives $60 Million Legacy Gift

Seattle Children’s today announced it has received the second largest single charitable gift in its 111-year history as the residual beneficiary of the estate of Bruce Leven. The landmark bequest is expected to exceed $60 million.

– Seattle Children's Hospital

ISPOR Announces a Brand Refresh for the Society

ISPOR, the professional society for health economics and outcomes research, announced today the launch of its new branding.

– ISPOR—The Professional Society for Health Economics and Outcomes Research

includes video

On-Screen, On-Demand, On-Time: The Future of Telemedicine at Penn Medicine

Penn Medicine Announces its new Center for Connected Care to centralize the health system’s telemedicine activities.

– Perelman School of Medicine at the University of Pennsylvania

Ocean Medical Center Receives Accreditation for Residency Programs in Family Medicine and Psychiatry

Ocean Medical Center received accreditation from the Accreditation Council for Graduate Medical Education (ACGME) for residency training programs in family medicine and psychiatry, practice areas in which there are serious shortages of physicians exp...

– Hackensack Meridian Health

Hackensack University Medical Center Orthopedic Surgeon Performs Groundbreaking Robotic-Assisted Total Knee Replacement Surgery

Hackensack University Medical Center is one of four centers in the country participating in a clinical trial to evaluate whether the TSolution One System is a safe and effective alternative to traditional knee replacement using manual surgical inst...

– Hackensack Meridian Health

Childhood Cancer Survivors, Hospital Host Fundraiser for Research

The Children’s Hospital University of Illinois will host an annual head-shaving event to raise money for the St. Baldrick’s Foundation.

– University of Illinois at Chicago

Wildlife Conservationists Encouraged by Cambodia’s Pursuit of Justice in Murder Case of Three Rangers And Committed to the Protection of Keo Seima Wildlife Sanctuary

The Wildlife Conservation Society is encouraged by the Cambodian Government’s actions pursuing justice in connection to the murder two weeks ago of three rangers, including one WCS staff member, and is committed to continue working with the authori...

– Wildlife Conservation Society

Science News

LJI researchers reveal how to undermine immune cell mobilization in allergic inflammation.

LJI researchers report mechanisms used by a subgroup of ILCs, known as ILC2 cells, to undergo maturation required for them to mount an effective immune response. These discoveries suggest a novel approach to treat inflammatory disease caused by overa...

– La Jolla Institute for Allergy and Immunology

Immunity; RO1AI123398; YFA0505802; YFC0903900; NSFC81630041

Embargo expired on 13-Feb-2018 at 12:00 ET

Drones Deliver Green Transportation Option

By getting your next package delivered by drone, you could be saving energy, but only if companies deploy drones sensibly. New research by Lawrence Livermore National Laboratory, Carnegie Mellon University, SRI International and the University of ...

– Lawrence Livermore National Laboratory

Nature Communications

Embargo expired on 13-Feb-2018 at 11:00 ET

Three’s Company: New Alloy Sets Magnetism Benchmark

Spintronics leverages electron spins to enhance solid-state devices by prolonging battery life. Spintronic developments, however, are increasingly running up against the Slater-Pauling limit, the maximum for how tightly a material can pack its magnet...

– American Institute of Physics (AIP)

Applied Physics Letters

Embargo expired on 13-Feb-2018 at 11:00 ET

In Effort to Treat Rare Blinding Disease, Researchers Turn Stem Cells into Blood Vessels

People with a mutated ATF6 gene have a malformed or missing fovea, severely limiting vision. UC San Diego School of Medicine researchers first linked ATF6 to this type of vision impairment. Now the team discovered that a chemical that activates ATF6 ...

– University of California San Diego Health

Science Signaling; EY027335; I01BX002284; N09G-302

Embargo expired on 13-Feb-2018 at 14:00 ET

Cover Crops in Nitrogen’s Circle of Life

A circle of life–and nitrogen–is playing out in farms across the United States. And researchers are trying to get the timing right. The goal is to time nutrient release from cover crops to better match the nutrient needs of specific cash crops. ...

– American Society of Agronomy (ASA), Crop Science Society of America (CSSA), Soil Science Society of America (SSSA)

Soil Science Society of America Journal, Jan. 25, 2018

Rutgers-Led Innovation Could Spur Faster, Cheaper, Nano-Based Manufacturing

Engineers at Rutgers University–New Brunswick and Oregon State University are developing a new method of processing nanomaterials that could lead to faster and cheaper manufacturing of flexible thin film devices – from touch screens to window coa...

– Rutgers University-New Brunswick

RSC Advances ; Scientific Reports ; Rutgers Today

'Excess Emissions' Make Significant Contribution to Air Pollution

A study by Indiana University researchers shows that excess emissions -- which occur with plant shut-downs, start-ups and malfunctions, and not just in connection with natural disasters -- can make serious contributions to overall air pollution.

– Indiana University

Environmental Science & Technology Feb-2017

From 100,000 to 8: Representing Complex Aerosol Patterns with Far Fewer Particles

Study shows how aerosols interacting with clouds can be accurately captured by sparse set of representative particles.

– Department of Energy, Office of Science

Journal of Geophysical Research: Atmospheres 122, 9867 (2017). [DOI: 10.1002/2016JD026335]

Berkeley Lab Report Calls for Industry Attention to Ensuring Grid Reliability

In light of changes in how electricity is being both generated and consumed, the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) has written a new report analyzing challenges facing the nation’s electric grid and makin...

– Lawrence Berkeley National Laboratory

Can a Cockroach Teach a Robot How to Scurry Across Rugged Terrain?

Researchers build a robot that moves more like a cockroach.

– Johns Hopkins University

Bioinspiration & Biomimetics, Feb-2-2018; Bioinspiration & Biomimetics, Feb-2-2018; W911NF-17-1-0346

includes video

Missing Link to Novel Superconductivity Revealed at Ames Laboratory

Scientists at the U.S. Department of Energy’s Ames Laboratory have discovered a state of magnetism that may be the missing link to understanding the relationship between magnetism and unconventional superconductivity.

– Ames Laboratory

npj Nature Quantum Materials

Longer-Lived Animals Have Longer-Lived Proteins

Researchers studying half-lives of evolutionarily related proteins in different species uncovered a link between species lifespan and protein lifespan.

– American Society for Biochemistry and Molecular Biology (ASBMB)

MCB-1350165 CAREER; R35 GM119502-01

New Turbulent Transport Modeling Shows Multiscale Fluctuations in Heated Plasma

Researchers at the DIII-D National Fusion Facility used a “reduced physics” fluid model of plasma turbulence to explain unexpected properties of the density profile inside a tokamak experiment. Modeling plasma’s turbulent behavior could help sc...

– American Institute of Physics (AIP)

Physics of Plasmas

Researchers Quantify Nutritional Value of Soil Fungi to the Serengeti Food Web

A new study by Northern Arizona University scientists shows how much arbuscular mycorrhizal fungi contribute to the complex ecosystem that makes up the Serengeti.

– Northern Arizona University

Journal of Ecology

Mars Rocks: UNLV Helps Pinpoint Landing Spots for NASA’s 2020 Mission

UNLV research could help assess excavation sites for rover mission that hopes to secure evidence of past life on the red planet.

– University of Nevada, Las Vegas (UNLV)

Nature Communications

Every Rose Has Its Thorn — and Its Tick

When it comes to avoiding Lyme disease, know your forest. That's the cautionary tale from a new study which found that ticks in urban parks in Delaware dominated by an invasive rose bush were nearly twice as likely to be infected with Borrelia burgdo...

– Washington University in St. Louis

Parasites & Vectors

Meet the Director: Sergei Nagaitsev

This is one in a series of profiles on directors of the SC-stewarded user facilities. This profile features Sergei Nagaitsev, director of the Fermilab Accelerator Complex.

– Department of Energy, Office of Science

Perspective on Fuel Cells

In a new Perspective article, published in the Journal of The Electrochemical Society, researchers are aiming to tackle a fundamental debate in key reactions behind fuel cells and hydrogen production, which, if solved, could significantly bolster cle...

– The Electrochemical Society

Journal of The Electrochemical Society

Interdisciplinary Approach Yields New Insights Into Human Evolution

Vanderbilt biologist Nicole Creanza takes an interdisciplinary approach to human evolution--both biological and cultural--as editor of special themed issue of Philosophical Transactions of the Royal Society B.

– Vanderbilt University

Philosophical Transactions of the Royal Society B, volume 373, issue 1743

WVU Alumna Named 2018 Outstanding West Virginian

West Virginia University alumna Caitlin Ahrens (BS Geology and Physics, 2015) was chosen as the 2018 Jaycees Outstanding Young West Virginian for her role as a NASA ambassador and advocacy for young women in science.

– West Virginia University - Eberly College of Arts and Sciences

WCS Media Briefing: The Hi-Tech Tool Poachers Hate

1) SMART Connect allows rangers and conservation area managers to exchange critical information and transmit data in real time, 2) Developer of “SMART Connect” will explain how new tool can revolutionize protected area management, 3) SMART is cur...

– Wildlife Conservation Society

The Mysteries of Plasma and Solar Eruptions Earn PPPL Graduate an Astrophysics Prize

Article describes dissertation award for graduate of Princeton University Department of Astrophysical Sciences.

– Princeton Plasma Physics Laboratory

USDA Funds Maple Syrup Research at University of Rhode Island

The study, titled “Beneficial effects of maple syrup phytochemicals against inflammation associated with metabolic syndrome,” aims to evaluate the anti-inflammatory effects of a polyphenol-enriched maple syrup extract in mice fed a high-fat diet ...

– University of Rhode Island

Lifestyle & Social Sciences

March Madness Mentality: Faced with Chance to Win, Most Coaches Go for Tie

When faced with a choice between a “fast” option that offers a greater chance of ultimate victory but also a significant chance of immediate defeat, and a “slow” option with both a lower chance of winning and a lesser chance of immediate defe...

– Cornell University

Journal of Personality and Social Psychology, Jan-2018

2018 Economic Forecast: Does Steady Growth Obscure a Shaky Foundation?

Darden Professor Alan Beckenstein and colleague Nick Sargen, a Darden lecturer, offer their projections for the U.S. economy in the coming year. Their remarks were delivered at an event hosted by the Richard A. Mayo Center for Asset Management and th...

– University of Virginia Darden School of Business

How Much Did African-Americans Shape President Lincoln’s Views?

EVANSTON - First published in 1942, “They Knew Lincoln” by John E. Washington (1880-1964) sold out quickly and was never reprinted. The author, a pioneering of Black dentist who was also a public school teacher, delved into the question of how mu...

– Northwestern University

In Light of Winter Olympics, Sports Serve as an Equalizer

Dr. George Cunningham, professor in the Department of Health and Kinesiology, offers insight as to why sports act as such an effective mechanism in equalizing people of different backgrounds.

Expert Available

– Texas A&M University

Love and Courtship in the Digital Age

.More than 20 years later, platforms for pairing up – and the attitudes toward those who use them – have changed considerably. But is the proliferation of dating sites and mobile apps altering our courtship experiences and long-term relationships...

Expert Available

– Rutgers University

To Prevent Cyberattacks, Paper Suggests Agency Similar to National Transportation Safety Board

After arguably the worst year ever for cyberattacks and data breaches, Indiana University research suggests it may be time to create an independent cybersecurity agency board comparable in approach to the National Transportation Safety Board that inv...

– Indiana University

American Association of Colleges of Nursing Opposes Cuts to the Healthcare Workforce and Education in President's FY 2019 Budget

President Trump released the Administration's Fiscal Year (FY) 2019 budget yesterday, which proposes sweeping cuts to certain federal programs within the Department of Health and Human Services (HHS) and the Department of Education. The American Asso...

– American Association of Colleges of Nursing (AACN)

Olympic Medal-Winning Luge Sled has Clarkson Technology Behind It

A couple of Clarkson University Professors helped to create a portion of the sled Chris Mazdzer rode to his silver-medal finish on Sunday.

– Clarkson University

Media Invited to Register for 2018 Annual Meeting of Education Researchers

The American Educational Research Association’s annual meeting is the largest gathering of scholars in the field of education research.

– American Educational Research Association (AERA)

AERA Annual Meeting

UVA Darden Executive Education, Olympic Rower Challenge Team Dynamics in New Washington DC Area Program

Darden Executive Education is launching an innovative new team development program in the Washington, D.C., area. Aligning Teams for Growth and Change brings together high-performance individuals for workshop-based learning that focuses on tackling a...

– University of Virginia Darden School of Business

Northwestern Law Team Wins Regional Trial Championship

CHICAGO - A Northwestern Pritzker School of Law Bartlit Center trial team won the Midwest regional of the National Trial Competition over the weekend for the third year in a row and the fourth time in the last five years.

– Northwestern University

Business News

Nutrition Gap Between Rich and Poor Is Growing, but Don’t Blame Food Deserts, Researchers Say

For decades, the conventional wisdom has been that people living in food deserts—defined as areas lacking in supermarkets with fresh produce and other nutritious items—have little choice but to buy unhealthy food at drugstores or convenience stor...

– University of Chicago Booth School of Business


DHS S&T Announces Five Finalists in $300K Biothreat Prize Competition

Issued by DHS S&T in collaboration with OHA's National Biosurveillance Integration Center (NBIC), the challenge calls for the design of an early warning system that uses existing data to uncover emerging biothreats.

– Homeland Security's Science & Technology Directorate





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