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Newswise Special Wire
Tuesday, May 26, 2015

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Newswise Cancer Research Wire for 26-May-2015
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Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Study Finds Association Between Exposure to Aflatoxin and Gallbladder Cancer

In a small study in Chile that included patients with gallbladder cancer, exposure to aflatoxin (a toxin produced by mold) was associated with an increased risk of gallbladder cancer, according to a study in the May 26 issue of JAMA.

(Embargo expired on 26-May-2015 at 11:00 ET)

JAMA

– JAMA - Journal of the American Medical Association

Attitudes About Complementary and Alternative Medicine Predict Use Among Cancer Patients

Attitudes and beliefs about CAM were found to be a better predictor of CAM usage than socio-demographic factors alone – such as race, sex, or education – which are often used to describe CAM users but stop short of fully explaining what drives people to use them.

 • Image(s) embedded •  (Embargo expired on 26-May-2015 at 00:00 ET)

CANCER

– Perelman School of Medicine at the University of Pennsylvania

E-Cigarette Vapor—Even When Nicotine-Free—Found to Damage Lung Cells

With the use of e-cigarettes on the rise, especially among young people, research to uncover the health effects of e-cigs is becoming increasingly important. In a new study published ahead of print in AJP-Lung, researchers find that e-cig solution and vapors—even those that are nicotine-free—damage lung health.

(Embargo expired on 26-May-2015 at 00:00 ET)

– American Physiological Society (APS)

Trending Stories Report for 26 May 2015

Trending news releases with the most views in a single day. Topics include: genetics and cancer, diabetes and blindness, nanotech, engineering, personalized medicine, energy, and e-cigarettes.

– Newswise Trends

Clinical Trial Reduces Stress of Cancer Caregivers

Cancer caregivers are stressed, potentially impacting the quality of the care they give. A University of Colorado Cancer Center clinical trial demonstrates how to help.

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Bone Marrow Transplantation; R01 CA126971/CA/NCI NIH HHS/United States

– University of Colorado Cancer Center

Ludwig Scientists to Report Advances in Treatment of Brain, Skin, Gastrointestinal Cancers at 2015 ASCO Annual Meeting

Ludwig Cancer Research previewed today the new findings that will be presented by Ludwig scientists at this year’s American Society for Clinical Oncology Annual Meeting in Chicago, Ill., May 29 – June 2. Ludwig researchers will present recent data from early and late stage clinical trials and participate in a number of plenary and educational sessions.

2015 ASCO Annual Meeting

– Ludwig Cancer Research

Ovarian Cancer-Specific Markers Set the Stage for Early Diagnosis, Personalized Treatments

Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have now identified six mRNA isoforms (bits of genetic material) produced by ovarian cancer cells but not normal cells, opening up the possibility that they could be used to diagnose early-stage ovarian cancer. What’s more, several of the mRNA isoforms code for unique proteins that could be targeted with new therapeutics.

(Embargo expired on 25-May-2015 at 15:00 ET)

Proceedings of the National Academy of Sciences

– University of California, San Diego Health Sciences

Removing Mutant p53 Significantly Regresses Tumors, Improves Cancer Survival

Removing accumulated mutant p53 protein from a cancer model showed that tumors regress significantly and survival increases. This finding, by an international team of cancer researchers led by Ute Moll, MD, Professor of Pathology at Stony Brook University School of Medicine, is reported in a paper published advanced online May 25 in Nature.

 • Image(s) embedded •  (Embargo expired on 25-May-2015 at 11:00 ET)

Nature

– Stony Brook University

Researchers Unveil New Gene Subgroup in Prostate Cancer

Prostate cancer researchers have drawn a molecular portrait that provides the first complete picture of localized, multi-focal disease within the prostate and also unveils a new gene subgroup driving it.

(Embargo expired on 25-May-2015 at 11:00 ET)

Nature Genetics

– University Health Network (UHN)

Nanotechnology Identifies Brain Tumor Types Through MRI “Virtual Biopsy” in Animal Studies

Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through “virtual biopsies” and then attack the molecular structure of the disease.

ACS Nano

– Cedars-Sinai Medical Center

Microfluidic Cell-Squeezing Device Opens New Possibilities for Cell-Based Vaccines

MIT researchers have shown that they can use a microfluidic cell-squeezing device to introduce specific antigens inside the immune system’s B cells, providing a new approach to developing and implementing antigen-presenting cell vaccines.

 • Image(s) embedded •  (Embargo expired on 22-May-2015 at 05:00 ET)

Scientific Reports, May-2015

– Koch Institute for Integrative Cancer Research at MIT

Trending Stories Report for 22 May 2015

Trending news releases with the most views in a single day. Topics include: swelling magnets; using genetics to fight dengue fever; cybersecurity; Hubble finds 'Nasty' star; ventilation and patient survival; food security; gamification in business; and cancer research on implants to improve glioma treatment.

– Newswise Trends

Imaging Technique Identifies Early Metastasis in Lymph Nodes

NIBIB-funded researchers have developed a highly sensitive imaging technique for non-invasive screening of lymph nodes for metastatic cancer. The new imaging technique – so far tested in mice – offers a rapid tool to noninvasively identify cancer’s spread at its earliest stages.

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Cancer Research, Oct-2014

– National Institute of Biomedical Imaging and Bioengineering

Dartmouth Researchers Use Implantable Micro-Device to Monitor Oxygen in Glioma to Improve Treatment Outcomes

Monitoring oxygen levels in human tumors growing in a mouse brain using EPR oximetry with implantable resonators provides opportunities to evaluate and optimize various strategies being developed to improve oxygen levels in the glioma.

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International Journal of Cancer; The Prouty; CA117874; CA23108; 1S10RR25048; CA120919

– Norris Cotton Cancer Center Dartmouth-Hitchcock Medical Center

The Medical Minute: Cancer Patients Benefit From an Active Lifestyle

When diagnosed with cancer, patients expect the standard treatments of chemotherapy, radiation and surgery. However, additional integrated therapies can address the needs of both body and mind when battling or recovering from cancer.

– Penn State Milton S. Hershey Medical Center

Pilot Clinical Trial Finds Injected Immune Cells Safe in Multiple Myeloma Patients

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients’ own bone marrow to treat multiple myeloma, a cancer of white blood cells.

(Embargo expired on 20-May-2015 at 14:00 ET)

Science Translational Medicine; 5P01 CA015396; P30 CA006973

– Johns Hopkins Medicine

Surgery Followed by Ipilimumab Treatment in Melanoma Patients Improves Survival

Melanoma is predicted to result in approximately 10,000 deaths in 2015. The majority of these deaths are due to advanced stage disease that has spread or metastasized to other sites. The prognosis for patients with metastatic melanoma remains poor, with 5-year survival rates of 63 percent in patients who have metastatic disease in regional lymph nodes, and only 17 percent in patients who have metastatic disease in distant sites. Moffitt Cancer Center researchers participated in an international phase 3 study that demonstrated that a drug called ipilimumab improves the relapse-free survival of advanced stage melanoma patients rendered free of disease surgically but at high risk for relapse.

The Lancet, May-2015

– Moffitt Cancer Center

Collaborative Research Team Solves Cancer-Cell Mutation Mystery

More than 500,000 people in the United States die each year of cancer-related causes. Now, emerging research has identified the mechanism behind one of the most common mutations that help cancer cells replicate limitlessly.

Science, May 14 2015

– Carl R. Woese Institute for Genomic Biology

Researchers Focus on Potential Tool for Predicting Survival, Staging Prostate Cancer in Cancer Cell

Researchers with the Indiana University School of Medicine have identified a molecule that promotes metastasis of advanced prostate cancer to the bone, an incurable condition that significantly decreases quality of life. The research, published online in the journal Cancer Cell, may offer new targets for diagnosing and treating this common disease.

Cancer Cell; R01CA69158, U01CA143057, PC061185, PC040341

– Indiana University

Trending Stories Report for 20 May 2015

Trending news releases with the most views in a single day. Topics include: neurology and hearing, nanotech and bionics, sound and psychology, , smoking and cancer, skipping meals and weight gain, 3D printing, sunscreen and skin cancer, urology, and cancer research.

– Newswise Trends

Nanotherapy Effective in Mice with Multiple Myeloma

Researchers at Washington University School of Medicine in St. Louis have designed a nanoparticle-based therapy that is effective in treating mice with multiple myeloma, a cancer of immune cells in the bone marrow. Targeted specifically to the malignant cells, these nanoparticles protect their therapeutic cargo from degradation in the bloodstream and greatly enhance drug delivery into the cancer cells.

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Molecular Cancer Therapeutics

– Washington University in St. Louis

Study Finds Biomarker May Boost Ovarian Cancer Chemotherapy Response

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer.

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Journal of the National Cancer Institute

– University of Texas M. D. Anderson Cancer Center

Molecule Designed to Treat Lung Cancer Shows Promising Results in Mice

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide.

EMBO Molecular Medicine

– Johns Hopkins Medicine

Announcements

Memorial Sloan Kettering Cancer Center Receives Record Gift of $150 Million from David Koch for Innovative Patient Care Facility

Memorial Sloan Kettering Cancer Center (MSK) announced that it has received the largest gift in its history, a commitment of $150 million from long-time MSK board member David H. Koch. This unprecedented contribution will transform cancer care with a state-of-the-art outpatient medical facility to be known as The David H. Koch Center for Cancer Care.

– Memorial Sloan Kettering Cancer Center

Tyler Jacks Receives MIT Faculty's Top Honor

Tyler Jacks, a pioneering cancer biologist and director of MIT’s Koch Institute for Integrative Cancer Research, is this year’s recipient of MIT’s James R. Killian Jr. Faculty Achievement Award. The Killian Award is the highest honor MIT grants to members of its faculty.

– Koch Institute for Integrative Cancer Research at MIT

CPRIT Awards $16.6 Million for Cancer Research, Prevention, and Faculty Recruitment at UT Southwestern Medical Center

The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded UT Southwestern Medical Center researchers more than $12.6 million in research grants for cancer research and prevention, as well as an additional $4 million for recruiting cancer scientists.

– UT Southwestern Medical Center

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