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Newswise Special Wire
Tuesday, August 18, 2015

Public edition | newswise.com

Newswise Cancer Research Wire for 18-Aug-2015
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Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Powdered Cranberry Combats Colon Cancer in Mice

Cranberries are often touted as a way to protect against urinary tract infections, but that may be just the beginning. Cranberry extracts reduced the size and number of colon tumors in mice, say researchers. Identifying the therapeutic molecules in the fruit could lead to a better understanding of its anti-cancer potential, they say. The team will describe their approach at the 250th National Meeting & Exposition of the American Chemical Society.

(Embargo expired on 18-Aug-2015 at 05:00 ET)

250th National Meeting & Exposition of the American Chemical Society (ACS)

– American Chemical Society (ACS)

Study Compares Heparin to Warfarin for Treatment of Blood Clots in Patients with Cancer

Among patients with active cancer and acute symptomatic venous thromboembolism (VTE; blood clots in the deep veins), the use of the low molecular-weight heparin tinzaparin daily for 6 months compared with warfarin did not significantly reduce recurrent VTE and was not associated with reductions in overall death or major bleeding, but was associated with a lower rate of clinically relevant nonmajor bleeding, according to a study in the August 18 issue of JAMA.

(Embargo expired on 18-Aug-2015 at 11:00 ET)

JAMA

– JAMA - Journal of the American Medical Association

Liver Damage in Hepatitis C Patients Significantly Underestimated and Underreported

The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the U.S. Centers for Disease Control and Prevention. The findings were the result of a study of nearly 10,000 patients suffering from hepatitis C, and could have a significant effect on patient care and healthcare policy regarding the chronic disease.

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American Journal of Gastroenterology, July-2015

– Henry Ford Health System

Every Step Along the Way

Flynn Fellowship honors oncology nurses by helping more of them hit the ground running, launches at Hopkins Nursing

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– Johns Hopkins School of Nursing

First-of-Its-Kind Study From UH Seidman Cancer Center Finds Music Therapy Lowers Anxiety During Surgical Breast Biopsies

A first-of-its-kind study published in the Journal of Clinical Oncology finds that music therapy lessened anxiety for women undergoing surgical breast biopsies for cancer diagnosis and treatment. The two-year study out of University Hospitals Seidman Cancer Center involved 207 patients. The randomized controlled trial tested music therapy for anxiety management with women undergoing outpatient breast cancer surgery, and it is the largest study of its kind to use live music therapy in the surgical arena.

 • Video embedded •  (Embargo expired on 17-Aug-2015 at 16:00 ET)

– University Hospitals Case Medical Center

Drinking Coffee Daily May Improve Survival in Colon Cancer Patients

Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study from Dana-Farber Cancer Institute that reported this striking association for the first time.

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Journal of Clinical Oncology

– Dana-Farber Cancer Institute

Cells in Limbo Hold Clues for Tackling Cancer and Ageing

For some, TOR may bring to mind a Celtic mountain or perhaps an Internet privacy group. In the world of molecular biology it’s a cellular pathway that’s found in everything from yeast to mammals.

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Nature Cell Biology, Aug-2015

– MRC Clinical Sciences Centre/Institute of Clinical Sciences (ICS) Faculty of Medicine, Imperial College London

Smoking Cessation Drug Not Boosting Number of Smokers Who Quit

The introduction of a new prescription smoking-cessation aid, varenicline, in 2006 has had no significant impact on the rate at which Americans age 18 and older successfully quit smoking, according to a study led by researchers at University of California, San Diego School of Medicine.

Tobacco Control

– University of California, San Diego Health Sciences

Comprehending Chemotaxis

James Bear, PhD, uncovers the intricate mechanisms that allow certain cells to move, discoveries with implications for cancer metastasis.

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– University of North Carolina Health Care System

MD Anderson Study Reveals New Insight Into Tumor Progression

Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.

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Expert(s) available

Nature Cell Biology

– University of Texas M. D. Anderson Cancer Center

Scientists Discover a Pathway That Controls Cancer Cell Proliferation by Nutrients

The findings introduce new drug targets to selectively inhibit a key event in tumor cell progression.

 • Image(s) embedded •  (Embargo expired on 13-Aug-2015 at 12:00 ET)

Cell Reports

– Sanford Burnham Prebys Medical Discovery Institute

Study Validates Method for Patient Reporting of Cancer Drug-Related Adverse Events

In an article published in JAMA Oncology, a study led by a UNC Lineberger Comprehensive Cancer Center researcher and colleagues shows that a system they developed accurately and reliably captures the patient experience with cancer drug side effects.

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JAMA Oncology, August-2015

– University of North Carolina Health Care System

Transplant Recipients More Likely to Develop Aggressive Melanoma

Organ transplant recipients are twice as likely to develop melanoma as people who do not undergo a transplant, and three times more likely to die of the dangerous skin cancer, suggests new research led by a Johns Hopkins Bloomberg School of Public Health student.

Journal of Investigative Dermatology

– Johns Hopkins Bloomberg School of Public Health

Mayo Clinic-Led Study Validates Tool for Patient Reporting of Side Effects in Cancer Clinical Trials

A multicenter study involving Mayo Clinic researchers has found that the National Cancer Institute's Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE), was accurate, reliable and responsive, compared to other, established patient-reported and clinical measures. The study is published today in the journal JAMA Oncology.

JAMA Oncology

– Mayo Clinic

Tell-Tale Biomarker Detects Early Breast Cancer in NIH-Funded Study

Researchers have shown that MRI can detect the earliest signs of breast cancer recurrence and fast-growing tumors. Their approach detects micrometastases, breakaway tumor cells with the potential to develop into dangerous secondary breast cancer tumors elsewhere in the body. The approach may offer an improved way to detect early recurrence of breast cancer in women and men. The work was completed at Case Western Reserve University and was funded by the National Institute of Biomedical Imaging and Bioengineering, part of NIH.

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Nature Communications, Aug 12, 2015; EB00489

– National Institute of Biomedical Imaging and Bioengineering

Pancreas Cancer Spread From Multiple Types of Wayward Cells

Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different organs. Groups of these cancer cells are better than single cancer cells in driving tumor spread.

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Cancer Discovery; CA169123, CA076931

– Perelman School of Medicine at the University of Pennsylvania

New Simple Proteins Play Active Role in Cellular Function

Yale scientists have developed simple new proteins almost devoid of chemical diversity that still play a surprisingly active and specific role in cellular function, causing cells to act like cancer cells, they report Aug. 10 in the Proceedings of the National Academy of Sciences.

Proceedings of the National Academy of Sciences

– Yale Cancer Center

Radiation Costs Vary Among Medicare Patients with Cancer

Cost of radiation therapy among Medicare patients varied most widely because of factors unrelated to a patient or that person’s cancer, report University of California, San Diego School of Medicine researchers in the Journal of Oncology Practice.

Journal of Oncology Practice

– University of California, San Diego Health Sciences

Novel Therapeutic Agent for Pediatric Cancer Developed at UC San Diego in Clinical Trials

Donald L. Durden, MD, PhD, pediatric researcher at University of California, San Diego School of Medicine and Moores Cancer Center has identified and developed a novel therapeutic target for neuroblastoma, the second most common solid-tumor childhood cancer. The agent, named SF1126, acts by inhibiting the part of the cancer cell engine that promotes tumor angiogenesis and growth.

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– University of California, San Diego Health Sciences

Cedars-Sinai Medical Tip Sheet for Aug. 2015

The August tip sheet includes story ideas related to prostate and breast cancer research, an enhanced Cedars-Sinai footprint, and the establishment of the Dr. Jerry H. Buss Surgical Oncology Fellowship.

– Cedars-Sinai

Announcements

UNM Cancer Center Awarded National Cancer Institute’s Highest Comprehensive Designation

The University of New Mexico Cancer Center (UNMCC) has been awarded the highest designation and rating in the United States for cancer treatment and research programs. It has received the National Cancer Institute’s “NCI Comprehensive Cancer Center” designation, identifying it as one of the leading cancer centers in the nation and the only such cancer center in New Mexico.

P30CA118100

– University of New Mexico Cancer Center

UK Researcher Awarded Grant to Study Link Between Obesity and Cancer

The National Cancer Institute (NCI) recently awarded a $750,000 grant to University of Kentucky researcher Fredrick Onono to study the potential link between obesity and breast cancer.

1K01CA197073-01

– University of Kentucky

Expert Pitch

Can Stem Cells Cause and Cure Cancer?

– Texas A&M University

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