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Newswise Special Wire
Tuesday, October 6, 2015

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Newswise Cancer Research Wire for 06-Oct-2015
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Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Binghamton University Professor Fights Cancer with Hedgehogs

A Binghamton University biochemist has discovered a new way to fight cancer, one that attacks only the cancer cells and promises fewer side effects. He hunts hedgehogs. Hedgehogs are proteins that help govern how cells develop. Normally, once a person reaches maturation, the hedgehogs turn off. But in some cancers — prostate, pancreatic, ovarian and lung in particular — the hedgehogs somehow turn back on, and force uncontrolled cell growth: cancer.

the Journal of Biological Chemistry, March-2015; Chembiochem, Jan-2015

– Binghamton University, State University of New York

Dallas Cowboys, American Academy of Dermatology Unite to Tackle Skin Cancer

In an effort to promote skin cancer prevention and detection, the American Academy of Dermatology and the Dallas Cowboys are teaming up to host free SPOTme® skin cancer screenings at Rally Day on Saturday, Oct. 10, from 8 a.m. to 1 p.m.

– American Academy of Dermatology

Tell “Skin Cancer, Take a Hike!”

With one in five Americans developing skin cancer in their lifetime, dermatologists, skin cancer survivors and their families and friends are asking everyone to tell “Skin Cancer, Take a Hike!™” On Saturday, November 7, 2015 at 10 a.m., a 2.5-mile hike will be held at Barton Creek Habitat Preserve, located near Bee Cave Road and Highway 71 in Austin

– Baylor Scott & White Health

Patients with Melanoma Skin Cancers don’t Regularly Perform Thorough Skin Self-Exams

It is recommended that melanoma patients perform a thorough skin self-exam on a regular basis to look for potential disease recurrence or new melanomas. Research by Rutgers Cancer Institute of New Jersey shows fewer than 15 percent of melanoma patients surveyed regularly examine all parts of their body.

 • Image(s) embedded • 

Melanoma Research, Sept-2015

– Rutgers Cancer Institute of New Jersey

New Evidence for a Strategy to Identify Patients Nearing the End of Life

ALEXANDRIA, Va. – A new study provides compelling evidence that a simple tool can help predict which patients with cancer may be in their final year of life. The tool, known as the Surprise Question, was found to predict the risk of cancer death within one year better than factors such as cancer type or stage alone. This study will be presented at the upcoming 2015 Palliative Care in Oncology Symposium in Boston.

2015 Palliative Care in Oncology Symposium

– American Society of Clinical Oncology (ASCO)

Panel Recommends Primary Palliative Care Services for Medical Oncology Practices

A new guidance statement from the American Society of Clinical Oncology and the American Academy of Hospice and Palliative Medicine is being presented for the first time at the 2015 Palliative Care in Oncology Symposium in Boston.

2015 Palliative Care in Oncology Symposium

– American Society of Clinical Oncology (ASCO)

Innovative Collaboration Among Radiation Oncologists and Palliative Care Specialists Improves Care for Patients With Advanced Cancers

An innovative service model that partners radiation oncology with palliative care leads to better results for patients, according to a new analysis. The model of care, established at Mount Sinai Medical Center in New York, is one of only a handful in the country.

2015 Palliative Care in Oncology Symposium

– American Society of Clinical Oncology (ASCO)

Predictive Model Could Help Guide Choices for Breast Cancer Therapies

Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.

 • Image(s) embedded • 

Scientific Reports

– Georgia Institute of Technology

Researchers Design ‘Biological Flashlight’ Using Light-Producing Ability of Shrimp

A UNC Lineberger Comprehensive Cancer Center researcher and his partners describe the design and engineering of the new bioluminescent imaging tool called the “LumiFluor” in a study published in the journal Cancer Research.

 • Image(s) embedded • 

Cancer Research, Oct-2015

– University of North Carolina Health Care System

Preventing Cancer: Study Finds Dramatic Benefits of Weight-Loss Surgery

A study evaluating the effects of bariatric surgery on obese women most at risk for cancer has found that the weight-loss surgery slashed participants’ weight by a third and eliminated precancerous uterine growths in those who had them. Other effects included improving patients’ physical quality of life, improving their insulin levels and ability to use glucose – which may reduce their risk for diabetes – and even altering the composition of their gut bacteria.

 • Image(s) embedded • 

Gynecologic Oncology

– University of Virginia Health System

Study Shows New ‘Driver’ to Assess Cancer Patient Survival and Drug Sensitivity

Cancer specialists have long looked at genetic mutations and DNA copy changes to help predict patient survival and drug sensitivity.

 • Image(s) embedded •  (Embargo expired on 01-Oct-2015 at 12:00 ET)

Cancer Cell; CA168394

– University of Texas M. D. Anderson Cancer Center

Genes of Colon Cancer Recurrence Differs Among Blacks, Whites and Asians, Mayo Clinic Study Finds

ROCHESTER, Minn. — The genetic makeup of colon cancer tumors and survival rates for patients with the disease differ by race, according to a study from researchers at the Mayo Clinic Cancer Center, published in the October 2015 issue of the Journal of the National Cancer Institute.

Journal of the National Cancer Institute

– Mayo Clinic

Proton Therapy Offers Hope for Patients with Locally Advanced Stage III Breast Cancer

In 2015, more than 1,650,000 new cases of breast cancer will be diagnosed in women in the United States, according to the American Cancer Society. Although many types of breast cancer are curable, traditional treatment methods can expose the heart, lungs, and other organs to radiation, resulting in an increased risk of long-term side effects. Proton beam therapy offers hope to women diagnosed with locally advanced stage III breast cancer, by targeting the tumor while reducing damage to healthy tissue. To provide evidence supporting this, experts from Seattle Cancer Care Alliance (SCCA) Proton Therapy Center are currently participating in a Patient-Centered Outcomes Research Institute (PCORI) trial to compare the effectiveness of proton beam radiation to conventional photon radiation in treating certain breast cancers.

– Seattle Cancer Care Alliance, Proton Therapy Center

UNC Lineberger Researcher Partnering to Develop Rapid Oral HPV Test

A UNC Lineberger Comprehensive Cancer Center researcher is a co-investigator with Sunnyvale, Calif.,-based InSilixa Inc. for the development of a rapid oral HPV test.

– University of North Carolina Health Care System

Rutgers Cancer Institute of New Jersey is One of Two National Sites to Offer a New Vaccine Trial for Bladder Cancer

Rutgers Cancer Institute of New Jersey is one of two sites in the nation offering a clinical trial targeting a specific type of bladder cancer with a vaccine treatment. Investigators will explore how effective the standard care for high grade non-muscle invasive bladder cancer is when combined with a poxvirus-based cancer treatment.

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– Rutgers Cancer Institute of New Jersey

Understanding Your Breast Cancer Diagnosis

For National Breast Cancer Awareness Month, Dr. Jean Simpson, a breast pathologist, offers information to help patients become more informed about their options and treatment process.

 • Image(s) embedded • 
Expert(s) available

– College of American Pathologists (CAP)

Penn-Developed, DNA-Based Vaccine Clears Nearly Half of Precancerous Cervical Lesions in Clinical Trial

Using a novel synthetic platform for creating vaccines originally developed in the laboratory of David Weiner, PhD, a professor of Pathology and Laboratory Medicine from the Perelman School of Medicine at the University of Pennsylvania, a team led by his colleagues at the Johns Hopkins University School of Medicine, has successfully eradicated precancerous cervical lesions in nearly half of the women who received the investigational vaccine in a clinical trial.

– Perelman School of Medicine at the University of Pennsylvania

Doctors Often Overtreat with Radiation in Late-Stage Lung Cancer

Almost half of patients with advanced lung cancer receive more than the recommended number of radiation treatments to reduce their pain, according to a new study published in the Journal of the National Cancer Institute.

Journal of the National Cancer Institute

– University of Illinois at Chicago

Sniffing Out Cancer with Improved 'Electronic Nose' Sensors

Researchers have developed a small array of flexible sensors, which accurately detect compounds in breath samples that are specific to ovarian cancer.

Nano Letters

– American Chemical Society (ACS)

Policy and Public Affairs

Penn Medicine Researcher Calls for Changes to Current Colorectal Cancer Screening Guidelines

Colorectal cancer will claim the lives of close to 50,000 Americans this year, according to the American Cancer Society. Screening is the most effective way to reduce the risk of dying from the disease, yet as a Penn Medicine physician argues in an editorial this week in the journal Gastroenterology, current recommendations to screen older people with a family history of colorectal cancer, specifically with colonoscopy every five years, is not justified for most patients. Chyke A. Doubeni, MD, MPH, chair of the department of Family Medicine and Community Health at the Perelman School of Medicine at the University of Pennsylvania, is the co-author of the editorial.

Gastroenterology

– Perelman School of Medicine at the University of Pennsylvania

Announcements

Laura and Isaac Perlmutter Cancer Center at NYU Langone Establishes Pioneering Program in Biologics

NYU Langone Medical Center is establishing a pioneering program in biologics research -- one of the country’s first academically-based programs of its kind --and has appointed Shohei Koide, PhD, an internationally renowned leader in protein engineering, to lead the new initiative.

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– NYU Langone Medical Center

APHON Announces the 2015 Membership Award Winners at its 39th Annual Conference

Chicago (Oct. 6, 2015): The Association of Pediatric Hematology/Oncology Nurses (APHON) announced the recipients of the 2015 APHON Membership Awards at its 39th Annual Conference and Exhibit, held September 17-19 in Providence, RI. APHON Membership Awards recognize members who have shown outstanding achievement in their field.

– Association of Pediatric Hematology/Oncology Nurses (APHON)

Smartphone-Based Device Provides Rapid Molecular Diagnoses at Low Cost

NIBIB-funded researchers at the Massachusetts General Hospital have developed a smartphone-based device that can reliably carry out molecular diagnoses in under an hour for approximately two dollars per patient. The device could enable point-of-care cancer diagnostics in low- to middle-income or remote areas, which often have high rates of mortality from cancer due to missed opportunities for treatment.

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Proc Natl Acad Sci U S A ; EB010011; EB00462605; HL113156; CA79443; CA087723

– National Institute of Biomedical Imaging and Bioengineering

UT Southwestern Launches ‘Call Out Cancer’ Initiative

UT Southwestern Medical Center today announced the launch of “Call Out Cancer,” a new health initiative designed to promote awareness, early detection, and prevention of all types of cancer.

 • Image(s) embedded •  (Embargo expired on 05-Oct-2015 at 07:00 ET)

– UT Southwestern Medical Center

UVA Named One of 11 U.S. Palliative Care Leadership Centers

The Center to Advance Palliative Care (CAPC) has named University of Virginia Health System as one of 11 Palliative Care Leadership Centers™ in the U.S.

– University of Virginia Health System

Ludwig Cancer Research to Play Key Role in NIH’s 4D Nucleome Program

Ludwig Cancer Research scientist Bing Ren has been tapped to play a key role in a major initiative launched by the US National Institutes of Health—a 4D Nucleome Program that will transform how we read and interpret the genome. The program is slated to receive $120 million over the next five years, depending on future appropriations and reviews of progress.

– Ludwig Cancer Research

FDA Approves Game-Changing Immunotherapy Drug to Fight Lung Cancer

The U.S. Food and Drug Administration today approved the breakthrough drug Keytruda to treat advanced non-small cell lung cancer, signaling a paradigm shift in the way the deadliest of all cancers is treated.

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– University of California, Los Angeles (UCLA), Health Sciences

UC Davis Granted $15.5 Million to Build World’s First Total-Body PET Scanner

A UC Davis research team has been awarded $15.5 million to build the world’s first total-body positron emission tomography (PET) scanner, which could fundamentally change the way cancers are tracked and treated and put the university on the nation’s leading edge of molecular imaging.

 • Video / Image(s) embedded •  (Embargo expired on 06-Oct-2015 at 10:00 ET)

– UC Davis Comprehensive Cancer Center

Nationally Acclaimed Oncologist Victoria Seewaldt Joins City of Hope

Nationally renowned breast cancer and ovarian cancer specialist Victoria L. Seewaldt, M.D., has joined City of Hope as the Ruth Ziegler Chair in Population Sciences. An expert in cancer prediction and prevention, Seewaldt will advance the institution’s efforts to ensure its research reflects and represents the diversity within City of Hope’s community.

– City of Hope

Higher Education Events

‘Lobos Love Pink’ Game Celebrates Breast Cancer Survivors

To raise awareness of breast cancer, the UNM Lobos, UNM Hospitals and UNM Comprehensive Cancer Center are sponsoring the “Lobos Love Pink” Football game.

– University of New Mexico Comprehensive Cancer Center

Act Once, Beat Nausea After Chemotherapy!

Attn: Infusion Center Oncology Nurses

Make low cost, FDA registered Pressure Right® wrist strips part of your multimodal approach to CINV. Cedars Sinai physicians (Los Angeles) in a randomized, sham-controlled, double-blind study concluded "...the adjunctive use of the disposable, noninvasive Pressure Right acupressure device enhanced the emetic efficacy of the most frequently used prophylactic antiemetic drug combination..."

Pressure Right wrist strips also continue to shield your patients from “delayed nausea and quality-of-life effects” in those vulnerable first days at home on a 24-hour basis.

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Contact us at therapeutics101@verizon.net or visit www.pressurerightstrips.com

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