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Interferon Not Beneficial for Most Stage III Melanoma

Final results for the Sunbelt Melanoma Trial, published online this month in the Journal of Clinical Oncology, show that thanks to current diagnostic techniques, most stage III melanoma patients do not benefit from treatment with interferon. See the full schedule.

Research News from National Labs and more with DOE Science News

Research news in high energy physics, materials science, environment, biology, nuclear physics and fusion, basic energy, supercomputing, and more. See the full schedule.

Assessing the Role of Autophagy in Prostate Cancer

Research from investigators at Rutgers Cancer Institute of New Jersey and colleagues shows the intracellular process of autophagy plays a role in the development of prostate cancer. See the full schedule.

(Embargo expired on 14-Feb-2016 at 17:00 ET)

Dr. Stan Riddell, an Innovator in Cancer Immunotherapy at Fred Hutch, Presents at AAAS Annual Meeting

Dr. Stanley Riddell, an immunotherapy researcher and oncologist at Seattle’s Fred Hutchinson Cancer Research Center, presented on Feb. 14 an update on new adoptive T-cell strategies for cancer at the annual meeting of the American Association for the Advancement of Science in Washington, D.C. See the full schedule.

Gene Previously Observed Only in Brain is Important Driver of Metastatic Breast Cancer

Scientists from The Wistar Institute have shown that one gene that was once thought only to be found in the brain is also expressed in breast cancer and helps promote the growth and spread of the disease. Additionally, they showed how a version of the gene with edited RNA prevents metastasis. See the full schedule.

(Embargo expired on 12-Feb-2016 at 05:00 ET)

New Nanotechnology Detects Biomarkers of Cancer

Researchers at Wake Forest Baptist Medical Center have developed a new technology to detect disease biomarkers in the form of nucleic acids, the building blocks of all living organisms. See the full schedule.

Long-Term Cancer Survivors Still Need Guidance About Screening, Side Effects, Lifestyle

A team of researchers from Yale School of Public Health and Yale Cancer Center recently published a study in the Journal of Cancer Survivorship that addresses the needs of cancer survivors who are at least nine years beyond an initial diagnosis. In the Q &A below, authors Mary Playdon, Tara Sanft, and Brenda Cartmel, talk about how to better care for long-term survivors. See the full schedule.

Software Optimized on Mira Advances Design of Mini-Proteins for Medicines, Materials

Scientists at the University of Washington are using Mira to virtually design unique, artificial peptides, or short proteins. Peptides have the best properties of two different classes of medical drugs today and could enable future, peptide-based medicines with few side effects. As researchers begin to develop new peptides, they are optimizing their in-house software to test thousands of potential peptide structure designs in tandem, requiring a state-of-the-art supercomputer. See the full schedule.

Alternative Proteins Encoded by the Same Gene Have Widely Divergent Functions in Cells

In a first large-scale systematic study, researchers at Dana-Farber Cancer Institute, University of California, San Diego School of Medicine, and McGill University found that most sibling proteins – known as “protein isoforms” encoded by the same gene – often play radically different roles within tissues and cells, however alike they may be structurally. See the full schedule.

(Embargo expired on 11-Feb-2016 at 12:00 ET)

Younger T Cells May Improve Immunotherapy for Children's Cancer

Pediatric oncologists from The Children's Hospital of Philadelphia have investigated techniques to improve and broaden a novel personalized cell therapy to treat children with cancer. The researchers say a patient's outcome may be improved if clinicians select specific subtypes of T cells to attack diseases like acute lymphoblastic leukemia and lymphoma. See the full schedule.

Plant Extract Shows Promise in Treating Pancreatic Cancer

A natural extract derived from India’s neem tree could potentially be used to treat pancreatic cancer, according to a new study in the journal Scientific Reports. See the full schedule.

Yale Study Examines Evolution of Cancer

A novel Yale study answers age-old questions about how cancers spread by applying tools from evolutionary biology. The new insights will help scientists better understand the genetic origins of tumor metastases, and lead to more effective targets for treatment, said the researchers. See the full schedule.

Experts and Research on the U.S. Supreme Court

Experts and research news on SCOTUS appointments, cases, the politics and the legal precedents of the United States' highest court. See the full schedule.

Meridian Health Partners with Rutgers Cancer Institute to Make PROGRESS Against Prostate Cancer

Meridian Health is joining forces with Rutgers Cancer Institute on research comparing the effectiveness of print versus online materials in helping prostate cancer patients cope with treatment-related and psycho-social challenges once therapy has ended. See the full schedule.

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.