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Newswise - News for Journalists

Newswise Special Wire
Tuesday, February 23, 2016

Public edition |

Newswise Cancer Research Wire for 23-Feb-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Mount Sinai Health System Experts Share Tips for Colorectal Cancer Awareness Month this March

Mount Sinai experts are available during March’s Colorectal Cancer Awareness month to discuss prevention, screening options, and risk factors.

Expert(s) available

– Mount Sinai Health System

Are Lung Cancer Survivors Getting Too Many Costly Scans for No Reason? Study Suggests So

Once you’ve made it through lung cancer treatment, you want to make sure you catch it early if it comes back again. But a new study suggests that one approach to watching for a cancer’s return is being inappropriately used at many hospitals. And it isn’t helping patients survive longer, the research shows.

(Embargo expired on 22-Feb-2016 at 16:00 ET)

J Natl Cancer Inst, 2016, Vol. 108, No. 7, doi:10.1093/jnci/djv429; HS20937; CA009672

– University of Michigan Health System

UCLA Scientists Advance Cancer Screening Technology to Better Personalize Cancer Treatment

Despite a growing interest in developing non-invasive methods to identify rare cancer cells or cancer cell DNA in blood, current techniques remain complicated and often prohibitively expensive. Now, UCLA researchers have pioneered a more effective approach to these “liquid biopsies” that has the potential to offer a streamlined and low-cost solution for people with the disease.

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– University of California, Los Angeles (UCLA), Health Sciences

Researchers Find Link Between Death of Tumor-Support Cells and Cancer Metastasis

NIH-funded researchers at Massachusetts General Hospital find surprising link between the death of tumor-support cells and an increased risk of cancer metastasis in mice.

 • Image(s) embedded •  (Embargo expired on 19-Feb-2016 at 05:00 ET)

Scientific Reports; EB012521; DK087770

– National Institute of Biomedical Imaging and Bioengineering

Researchers Work to Decipher Genetic Data in Hunt for New Prostate Cancer Treatments

Florida State University researchers are working on new approaches to deciphering genetic data that may lead to new, more targeted prostate cancer treatments.

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– Florida State University

High-Power Intravital Microscopy System Allows Tumor Blood Vessels to Be Seen in Real Time During Surgery

In the first study of intravital microscopy in humans, Roswell Park scientists report that this approach for visualizing tumor blood vessels in real time during surgery is not only feasible, but that it revealed unexpected findings about the vasculature of human tumors.

Nature Communications 6, Article number: 7458 doi:10.1038/ncomms8458; R01CA79765; P30CA016056; R01AI082039

– Roswell Park Cancer Institute

Pinpointing the Chromosomal Creation of Cancer

Yoshiaki Azuma, Ph.D., is analyzing the role of enzyme Topo II and how its functions may show how cancer mutations are born.

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R01 GMI1279302

– University of Kansas Cancer Center

Get the Latest Research and Features in the Field of Neuroscience and Neurology

Get the latest research and features in the field of Neuroscience and Neurology in the Newswise Neuro News Source.

– Newswise

3D Mammography Improves Cancer Detection and Cuts “Call Backs” Over Three Years

The increased cancer detection and reduced call backs associated with 3D mammography, also known as Digital Breast Tomosynthesis (DBT), can be maintained years after a patient’s first DBT screening with regularly scheduled DBT imaging, according to a JAMA Oncology study published online today from researchers at the Perelman School of Medicine at the University of Pennsylvania.

JAMA Oncology; U54CA163313

– Perelman School of Medicine at the University of Pennsylvania

Induction Chemotherapy Does Not Predict Survival Advantage Over Concurrent Chemoradiation for Locally Advanced Head and Neck Cancer

Head and neck cancer patients who receive induction chemotherapy (IC; chemotherapy administered prior to radiation therapy) rather than the standard treatment of concurrent chemoradiation (CRT) do not benefit from increased survival rates and are less likely to receive a full course of radiation, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– American Society for Radiation Oncology (ASTRO)

Uninsured and Medicaid Patients with Head and Neck Cancer More Likely to Present with Advanced Tumors, Experience Cancer Specific Mortality

Compared to patients with non-Medicaid insurance, uninsured patients and patients with Medicaid are more likely to present with advanced stages of head and neck cancer and have higher overall and cancer-specific mortality rates, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– American Society for Radiation Oncology (ASTRO)

Most Recurrences of HPV-Positive Oropharyngeal Cancer Can Be Found Through Imaging and Physical Exams Within Six Months After Treatment

For patients treated with definitive radiation therapy (RT) for oropharyngeal cancer caused by human papillomavirus (HPV), the majority of recurrences can be detected by post-treatment imaging at three months and physical exams during the six months following treatment, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– American Society for Radiation Oncology (ASTRO)

Chemoradiation May Increase Survival for a Subset of Elderly Head and Neck Cancer Patients

The addition of chemotherapy (CT) to radiation therapy (RT) improves survival rates among a subset of elderly head and neck cancer patients, specifically those ages 71 to 79 with low comorbidity scores and advanced disease stage, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– American Society for Radiation Oncology (ASTRO)

Majority of Patients with Locally Advanced Head and Neck Cancers Use Life-Altering Strategies to Cope with Cost of Treatment

The majority of patients with locally advanced head and neck cancers (LAHNC) rely on cost-coping strategies that alter their lifestyle in order to manage the financial burden of their care, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– American Society for Radiation Oncology (ASTRO)

Study Maps Distinct Molecular Signatures of HPV-Positive Throat Cancer Patients by Smoking Status

Throat cancer patients exposed to both human papillomavirus (HPV) and tobacco smoke demonstrate a pattern of mutations along several key cancer genes, according to research presented today at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– American Society for Radiation Oncology (ASTRO)

Study Finds Different Genetic Mutation Patterns for HPV-Positive Throat Cancer Patients Based on Smoking History

Preliminary findings from a study examining the genetic alterations in HPV-positive oropharyngeal squamous cell carcinoma were presented Thursday at the 2016 Multidisciplinary Head and Neck Cancer Symposium. The researchers found differences in the genetic mutations of HPV-positive oropharyngeal cancer based on whether patients were heavy versus light smokers.

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Multidisciplinary Head and Neck Cancer Symposium, Feb-2016

– University of North Carolina Health Care System

New Image Analytics May Offer Quick Guidance for Breast Cancer Treatment

For women with the most common type of breast cancer, a new way to analyze magnetic resonance images (MRI) data appears to reliably distinguish between patients who would need only hormonal treatment and those who also need chemotherapy. The analysis may provide women diagnosed with estrogen positive-receptor (ER-positive) breast cancer answers far faster than current tests and, due to its expected low cost, open the door to this kind of testing worldwide.

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Nature Scientific Reports Feb. 18, 2016

– Case Western Reserve University

The Latest Research and Features in Healthcare, including Hospital Administration, Patient Care, and Health Economics

Get the latest research and features in healthcare, including hospital administration, patient care, and health economics in Newswise's Healthcare News Source.

– Newswise

Kellogg Researchers Develop New Nanoparticle with Potential to Treat Ocular Cancer

Using nanoparticles to kill tumor cells inside the eye.


– University of Michigan Health System

Immune-Targeting Drug Combo Shows Promise for Non-Small Cell Lung Cancer Patients, Say Moffitt Researchers

Lung cancer is the most common cause of cancer-related death in the United States resulting in more than 158,000 deaths each year. With a 5-year survival rate at only 18 percent, the development of new and improved treatment options is needed. Moffitt Cancer Center researchers are leading the way in the creation of novel therapies. Most recently, Moffitt, in conjunction with partner institutions, initiated a multicenter phase 1b clinical trial to determine the safety and efficacy of a new drug combination for non-small cell lung cancer that stimulates a patient’s immune system to target and kill cancer cells.

Lancet Oncology

– Moffitt Cancer Center

Cancer Study Is ‘Paradigm Shift’ in Cause of Tumor Formation

In a new study published in the American Association of Cancer Research’s journal Cancer Research, a pair of investigators at Rutgers and Columbia universities has identified a gene that may provide a new source of potential drug targets for tumors that arise in pulmonary tuberous sclerosis complex (TSC). The discovery may change what is known about tumor formation and help to slow or halt tumor growth, therefore having broader implications in cancer research.

Cancer Research; W81XWH-05-1-0184; RO1-HL086936

– Rutgers Robert Wood Johnson Medical School

The Latest Cancer Research and Related Features at the Cancer News Source

See the latest cancer research and get pertinent informative features on the fight against cancer at Newswise's Cancer News Source.

– Newswise

New Predictor of Cancer

Epigenetic age is a new way to measure your biological age. When your biological (epigenetic) age is older than your chronological age, you are at increased risk for getting and dying of cancer, reports a new study. And the bigger the difference between the two ages, the higher your risk of dying of cancer. The research could be used to develop an early detection blood test for cancer.

NIEHS R01-ES015172

– Northwestern University

Low-Risk Prostate Cancer Best Managed with Active Surveillance, According to New Recommendations

A UNC Lineberger researcher was first-author of a report published in the Journal of Clinical Oncology that details guidelines for the active surveillance of men with low-risk prostate cancer. The guidelines, originally authored by Cancer Care Ontario, were reviewed and endorsed by the American Society of Clinical Oncology with some revisions.

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Journal of Clinical Oncology, Feb-2016

– University of North Carolina Health Care System

The Latest Research and Features in Children's Health and Pediatrics

Get the latest research and features in the field of children's health and pediatrics, including vaccinations, abuse, premature births, mental health, autism and more in the Newswise Children's Health News Source.

– Newswise

Dana-Farber Cancer Institute Using New Mobile Imaging Technique for Patient, Family, and Staff Therapeutic Self-Expression

Dana-Farber Cancer Institute and the EDI Institute are partnering to provide a new mobile imaging technique for cancer patients, family members, and staff to express their feelings around the illness. Expressive Digital Imagery (EDI) is used on a smartphone or tablet to provide a creative outlet for people to express complex feelings and emotions that words alone cannot.

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– Dana-Farber Cancer Institute

Sanford Clinical Trial Testing Investigational Cancer Drug

Dr. W. Chad Spanos leading study involving nivolumab

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– Sanford Health

RNA Modification Discovery Suggests New Code for Control of Gene Expression

A new cellular signal discovered by a team of scientists at the University of Chicago with scientists from Tel Aviv University provides a promising new lever in the control of gene expression.

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– University of Chicago

First-in-Class Drug ONC201 Shows Potential for Some Blood Cancers

ONC201, an anti-cancer drug that triggers cell death in various tumor types, may have clinical potential for some blood cancers including mantel cell lymphoma (MCL) and acute myeloid leukemia (AML), according to a recent clinical study.

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Science Signaling

– University of Texas M. D. Anderson Cancer Center

Injuries and Other Health Concerns Are More Common in Older People After Certain Cancer Surgeries

Older people who undergo cancer surgery are more likely than their younger counterparts to experience injuries and health issues such as falling down, breaking bones, dehydration, bed sores, failure to thrive and delirium.

– University of California, Los Angeles (UCLA), Health Sciences

MD Anderson Researchers Propose New Staging for HPV-Related Oropharyngeal Cancer

Current staging system is inadequate; for the first time, research proves that staging based on nasopharyngeal “N” categories offers more predictive value

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Journal of Clinical Oncology

– University of Texas M. D. Anderson Cancer Center


Laurie H. Glimcher, MD, Named President of Dana-Farber Cancer Institute

Laurie H. Glimcher, MD, an internationally recognized immunologist, has been named the next president and CEO of Dana-Farber Cancer Institute, the Board of Trustees announced today.

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– Dana-Farber Cancer Institute

Unique Next Generation Sequencing-Based Panel Designed for Pediatric Cancer Research

Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA’s first NGS panel designed to target biomarkers associated with childhood cancers.

– Childrens Hospital Los Angeles

Filing of State Application Launches UChicago Medicine’s Comprehensive Plan to Increase Access to Care on South Side

The University of Chicago Medicine is seeking state approval for a bold project that will address the lack of access to emergency and adult trauma services and complex care on the South Side.

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– University of Chicago Medical Center

MD Anderson Receives $14 Million in CPRIT Research Funding to Recruit Top Talent

The University of Texas MD Anderson Cancer Center was awarded $14 million this week from the Cancer Prevention and Research Institute of Texas (CPRIT) for the recruitment of three cancer scientists.

– University of Texas M. D. Anderson Cancer Center

NCCN, in Collaboration with Pfizer, Awards 10 Grants for Provider Performance and Quality in Treatment of Metastatic Breast Cancer Initiatives

NCCN and Pfizer elicited proposals for the development and adoption of evidence-based initiatives to improve patient care and outcomes in metastatic breast cancer; 10 grants were awarded.

– National Comprehensive Cancer Network® (NCCN®)


Cancer Center’s Collaboration Accelerates Research to Aid in the Development of Blood-Based Biomarkers

Wistar Institute - Graham Cancer Center collaboration speeds the advancement of promising lung caner diagnostic

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– Wistar Institute

Expert Pitch

Crafting a Better T Cell for Immunotherapy: New Technology, Not Yet Tested In Humans, Aims To Reduce Patients’ Waiting Time, Increase Potency Of T-Cell Therapy

 • Image(s) embedded •  (Embargo expired on 22-Feb-2016 at 11:00 ET)

– Fred Hutchinson Cancer Research Center

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