Is this email not displaying correctly?
View it in your browser.
Newswise - News for Journalists

Newswise Special Wire
Monday, March 14, 2016

Public edition |

Newswise Cancer Research Wire for 14-Mar-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

ROBO1 Helps Cells Put Up Stiff Resistance

A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, “Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness” by Lily Thao-Nhi Le and colleagues, identifies a signaling pathway that may protect breast cells from the tumorigenic effects of stiff extracellular matrices.

 • Image(s) embedded •  (Embargo expired on 14-Mar-2016 at 09:00 ET)

The Journal of Cell Biology, March 14th, 2016; CIRM FA1-00617-1; CIRM CL1-00506-1.2; NIH GM- 098897; NIH GM098897-02S1; NIH CA142833; NIH CA114462; NSF DGE 0809125...

– The Rockefeller University Press

First Injectable Nanoparticle Generator Could Radically Transform Metastatic Breast Cancer Treatment

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice. This landmark study appears today in Nature Biotechnology (early online edition).

 • Video / Image(s) embedded •  (Embargo expired on 14-Mar-2016 at 12:00 ET)

Nature Biotechnology, Advanced Online March 14, 2016; W81XWH-09-1-0212 and W81XWH-12-1-0414; U54CA143837 and U54CA151668

– Houston Methodist

New Drug Combination Shows Promise Against Childhood Brain Cancer

Researchers at SBP have identified a new combination therapy for the most aggressive form of medulloblastoma, a fast growing pediatric brain cancer. These results are expected to lead to a clinical trial.

 • Image(s) embedded •  (Embargo expired on 14-Mar-2016 at 12:00 ET)

Cancer Cell; NIH CA122759; NIH CA159859; CIRM LA1- 01747

– Sanford Burnham Prebys Medical Discovery Institute

Helping to Stop Colorectal Cancer by Identifying Metastasis Chances Early

Colorectal cancer, one of the most commonly diagnosed cancers in the United States, is not a commonly discussed disease. Often symptomless in early stages, the cancer is more difficult to treat as it progresses, requiring chemotherapy in later stages. Researchers at the University of Notre Dame are working on a way to identify patients who would benefit from chemotherapy before the cancer progresses.

 • Image(s) embedded • 
Expert(s) available

– University of Notre Dame

UT Southwestern Researchers Find Newly Identified Immunity Pathway Protects Mammals From Virus-Caused Cancer

Building upon earlier research, investigators at UT Southwestern Medical Center and their collaborators have identified a new innate immunity pathway that protects mammals from viral oncogenesis, the process by which viruses cause normal cells to become cancerous.

 • Image(s) embedded • 

Proceedings of the National Academy of Sciences, Feb-2016

– UT Southwestern Medical Center

Neurofeedback Reduces Pain, Increases Quality of Life for Cancer Patients Suffering From Chemotherapy-Induced Neuropathy

A new study from The University of Texas MD Anderson Cancer Center evaluating the use of neurofeedback found a decrease in the experience of chronic pain and increase quality of life in patients with neuropathic pain.

 • Image(s) embedded • 

American Psychosomatic Society

– University of Texas M. D. Anderson Cancer Center

What I Learned: 5 Lessons From Breast Cancer Survivor Amelia Tena

For many cancer survivors, being hit with the news that cancer has returned can be a devastating blow; a moment that tests the strength and courage of even the toughest of patients.

 • Video embedded • 

– City of Hope

Jefferson Researchers Find Highly Active Gene in Aggressive Human Lung Cancer

Scientists believe that “conserved” genes — those found in life forms that range from bacteria to plants, insects and humans — perform vital biological functions across species. And limited research on one of those genes, Nitrilase 1 (Nit1), suggested it acts to inhibit cancer development.

(Embargo expired on 10-Mar-2016 at 14:00 ET)

– Thomas Jefferson University

Negative Cancer Trials: Short-Term Whimper, Long-Term Bang

Cancer clinical trials with negative results don’t make an immediate splash in the scientific literature, but they do have a long-term impact on cancer research, according to a new study by SWOG, the federally funded international clinical trials network.

 • Image(s) embedded •  (Embargo expired on 10-Mar-2016 at 11:00 ET)

JAMA Oncology; 5UG1CA189974-01

– Fred Hutchinson Cancer Research Center

Light Exposure Improves Depressive Symptoms Among Cancer Survivors

Light therapy decreased depressive symptoms and normalized circadian rhythms among cancer survivors, according to new research from the Icahn School of Medicine at Mount Sinai presented at the American Psychosomatic Society in Denver, CO

(Embargo expired on 10-Mar-2016 at 17:30 ET)

American Psychosomatic Society

– Mount Sinai Health System

Widely Used Kidney Cancer Drugs Can't Stop Recurrence

Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.


– Perelman School of Medicine at the University of Pennsylvania

Rice Scientists Synthesize Anti-Cancer Agent

Trioxacarcin molecules bind to the DNA of targeted cells and prevent them from replicating.

 • Image(s) embedded • 

Journal of the American Chemical Society

– Rice University

Wake Forest Baptist Is First in the U.S. to Offer Scalp Cooling System to Reduce Hair Loss in Women with Breast Cancer

Wake Forest Baptist Medical Center is the first medical center in the United States to offer the FDA-cleared DigniCap scalp cooling system to patients undergoing chemotherapy for breast cancer.

– Wake Forest Baptist Medical Center

New Class of Drugs Specifically Induces Cell Death in B Cell Blood Cancers

New research from The Wistar Institute shows how one protein found on the endoplasmic reticulum can serve as a target for stimulating the immune system and a more direct target for cellular death in B cell malignancies.

 • Image(s) embedded • 

Cancer Research, Mar-2016

– Wistar Institute

UNC Researchers Discover Colorectal Cancer Biomarker, Potential Personalized Treatment

In the journal Cell Reports, UNC Lineberger researchers reported they found markedly low levels of the protein NLRX1 in multiple laboratory models of colorectal cancer, and in samples of human tissue. Studies have shown that the protein is known to be involved in regulating immune system signals in order to prevent hyperactive inflammatory responses by the immune system, but UNC Lineberger researchers believe their finding also points to a role for the protein in preventing colorectal cancer growth. Based on their findings, they believe they’ve identified a potential treatment for colorectal cancer with low NLRX1.

 • Image(s) embedded • 

Cell Reports, March-2016

– University of North Carolina Health Care System

Surgical Procedure Improves Survival Rates for Men with Prostate Cancer if Radiation Treatments Fail

Approximately 14 percent of men will be diagnosed with prostate cancer at some point in their lifetimes, according to the National Institutes of Health. Radiation therapy traditionally has been a primary treatment for the cancer, but one-fourth of men have a recurrence of prostate cancer within five years after the therapy. Now, a University of Missouri School of Medicine researcher has found that a complex procedure to remove the prostate achieves excellent long-term survival for men after radiation therapy has failed.

 • Image(s) embedded • 

Clinical Genitourinary Cancer

– University of Missouri Health

Nanotechnology Lab Opens in Florida to Research, Apply Minute Materials to Cancer Care

With support from the state of Florida, Mayo Clinic’s Florida campus has opened a state-of-the-art laboratory for nanotechnology research, an emerging field of science that studies and applies materials that are the size of an atom.

– Mayo Clinic

Mercy Breast Cancer Surgeon Dr. Neil B. Friedman Discusses Research Indicating an Increase in Mastectomies in Early Cancer Detection

Mercy breast cancer surgeon Dr. Neil B. Friedman discusses research indicating an increase in mastectomies in early cancer detection.

 • Video embedded • 
Expert(s) available

American Journal of Public Health; Journal of Immunotherapy

– Mercy Medical Center, Baltimore

High Coronary Calcium Score May Signal Increased Risk of Cancer, Kidney and Lung Disease

A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).

(Embargo expired on 09-Mar-2016 at 14:00 ET)

Journal of the American College of Cardiology: Cardiovascular Imaging; N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167...

– Johns Hopkins Medicine

Take Me to My Favorites!

Add Channels, Sources, Experts, and Save Articles for Later with My Reading List

(Embargo expired on 09-Mar-2016 at 09:00 ET)

– Newswise Recommends

Newswise Recommends Journal Related News

All Newswise articles citing journal-published research news

– Newswise Recommends

Children's Hospital of Michigan DMC Research Team Leads Cardiology Component of Clinical Trial to Protect the Hearts of Children Who Receive Chemotherapy

Published in the upcoming March 10, 2016 issue of the authoritative Journal of Clinical Oncology, this new study is likely to change the standard of cardiac care during treatment of many childhood cancer patients.

 • Image(s) embedded • 

Journal of Clinical Oncology, March-2016; U10 CA098543, U10 CA098413

– Children's Hospital of Michigan

ASCO to Hold Capitol Hill Briefing March 15 on The State of Cancer Care in America: 2016

The State of Cancer Care in America: 2016 report, to be released on March 15 by the American Society of Clinical Oncology (ASCO), chronicles the current realities of the cancer care delivery system in the United States and examines trends in the oncology workforce and practice environment that are affecting patient care and access.

– American Society of Clinical Oncology (ASCO)

Boise State NSF CAREER Award Could Lead to New Disease Treatments

The use of proteins to identify a single molecule in a solution could be extremely important for early diagnosis of cancer, much earlier than is possible with current technology.

 • Image(s) embedded • 

– Boise State University

A Stress-Reduction Intervention for Caregivers of Pediatric Stem Cell Transplant Patients Shows Benefit

Research from an investigator at Rutgers Cancer Institute of New Jersey and colleagues from other facilities across the country, shows a social-cognitive intervention designed for parents of children undergoing a stem cell transplant had beneficial effects in reducing caregiver distress during the hospitalization period as compared with current best-practice psychosocial care.

 • Image(s) embedded • 

Journal of Consulting and Clinical Psychology, Feb-2016; CA127488

– Rutgers Cancer Institute of New Jersey

Baylor College of Medicine, Baylor Scott & White Health Announce Collaboration on Biomedical Research

Baylor College of Medicine and Baylor Scott & White Health have entered into an agreement to expand biomedical research in North and Central Texas. Bringing together the strengths of both institutions, the goal of this collaboration is to accelerate efforts to provide new therapies to the residents of Texas and beyond.

 • Image(s) embedded • 

– Baylor Scott & White Health

Team Finds New Approach to Curbing Cancer Cell Growth

Using a new approach, scientists at The Scripps Research Institute and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.

 • Image(s) embedded • 

Proceedings of the National Academy of Sciences; P01 CA117969 and P01 CA120964

– Scripps Research Institute

How Cancer Cells Fuel Their Growth

Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar.

Developmental Cell

– Massachusetts Institute of Technology (MIT)

Clinical Review Explores Role of Rt in BRCA1, BRCA2 Mutation Breast Cancer Treatment

In light of conflicting and inconclusive clinical data on the benefit of radiation therapy in cancer patients with the BRCA1 and BRCA2 mutation, a clinical review examined the current status of data regarding BRCA1 and BRCA2 deficiency and radiation therapy sensitivity and a potential strategy to intensify the effects of radiation therapy (RT) by poly(ADP-ribose) polymerase inhibitors (PARPi), the pharmacologic drugs under investigation as monotherapy for the treatment of breast cancer in patients with BRCA1 and BRCA2 mutations.

International Journal of Radiation Oncology*Biology*Physics, Oct-2015

– American Society for Radiation Oncology (ASTRO)

UC San Diego Health and Vantage Oncology Announce Cancer Care Collaboration

UC San Diego Health and Vantage Oncology are collaborating to provide comprehensive cancer care services to patients in Imperial Valley. Through a joint venture, UC San Diego Health and Vantage will operate Imperial Valley Radiation Oncology. Patients will have access to advanced radiation technologies as well as clinical trial interventions and specialty care consultations with UC San Diego Health and Moores Cancer Center.

– University of California, San Diego Health Sciences


Meridian Cancer Care Expands Access to Services with Addition of Local, Trusted Practice

Hematology and oncology expertise now available at Meridian Health Village at Jackson.

 • Image(s) embedded • 

– Meridian Health

Fred Hutch Researcher Receives Grant for Esophageal Cancer Screening Study

Dr. William Grady, a clinical researcher and cancer geneticist at Fred Hutch, has been awarded a $180,000 grant from the DeGregorio Family Foundation for Gastric and Esophageal Cancer Research and the Price Family Foundation for a two-year project to develop a better way to identify people at highest risk for esophageal adenocarcinoma, the most common cancer of the esophagus.

 • Image(s) embedded • 

– Fred Hutchinson Cancer Research Center

FDA Approves New ACR Digital Mammography Quality Control Manual

The Food and Drug Administration (FDA) approved the American College of Radiology’s (ACR’s) alternative standard request to allow mammography facilities to use the new Digital Mammography Quality Control (QC) Manual and Digital Mammography QC Phantom in routine QC of digital equipment.

– American College of Radiology (ACR)

Orlando Health Unveils Name for Highly Anticipated Proton Therapy Center

In just a matter of weeks Orlando Health will open the first proton therapy center in Central Florida, providing patients with a valuable new tool in the fight against cancer. Now, that center has a name, and one with special meaning - The Marjorie and Leonard Williams Center for Proton Therapy. Marjorie Williams, a patient at UF Health Cancer Center - Orlando Health, passed away in September of 2015 following a courageous battle with cancer. In her memory, her husband, Leonard, and the Williams Family Foundation is providing a leadership gift in her name to Orlando Health to support proton therapy treatment.

 • Image(s) embedded • 

– Orlando Health

subscribe/unsubscribe :: edit my preferences
© 2016 Newswise, Inc. All Rights Reserved. | 215 E. 5th St. SW, Charlottesville VA 22903 | 434-296-9417 | Contact Us