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Newswise Special Wire
Tuesday, March 29, 2016

Public edition |

Newswise Cancer Research Wire for 29-Mar-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

For Prostate Cancer, More Radiation May Not Improve Survival

Increasing the total dose of radiation to patients with non-metastatic prostate cancer does not improve their long-term outcomes, according to a new study.

– Thomas Jefferson University

UCI-Stanford Study Finds Cessation Program Delivered on Twitter to Be Twice as Effective as Other Methods for Helping Smokers Quit

A new study by researchers from UC Irvine and Stanford University found subjects in one of the first real-time, fully automated, Twitter-based smoking intervention programs – Tweet2Quit -- were twice as successful at kicking the habit as those using traditional methods. The new findings were recently published online in Tobacco Control, an international peer reviewed journal. The print version of the research is forthcoming.

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Tobacco Control; NIH R34 Innovation DA030538

– University of California, Irvine, The Paul Merage School of Business

NUS Researchers Found New Clue to Fighting Acute Myeloid Leukaemia

A study led by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has uncovered a new clue that may help fight acute myeloid leukaemia (AML), the most common form of cancer of the blood and bone marrow, and an aggressive type of cancer. The findings open a new door to treating the disease more effectively.

Nature Communications

– National University of Singapore

Katie Couric’s Personal Reflection Published in The American Journal of Gastroenterology

Katie Couric reflects on her unanticipated journey as a cancer advocate in a personal essay published online in The American Journal of Gastroenterology to coincide with March National Colorectal Cancer Awareness Month.

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Amer Journal of Gastroenterology, Advance Online Mar-2016

– American College of Gastroenterology (ACG)

UCLA Researcher Advances PET Imaging Technology to Improve Patient’s Response to Cancer Treatment

A promising new discovery by UCLA scientists could lead to a new method of identifying cancer patients that express high levels of an enzyme and are more likely to respond to cancer treatments.

 • Image(s) embedded •  (Embargo expired on 28-Mar-2016 at 15:00 ET)

– University of California, Los Angeles (UCLA), Health Sciences

How Cancer Stem Cells Thrive When Oxygen Is Scarce

Working with human breast cancer cells and mice, scientists say new experiments explain how certain cancer stem cells thrive in low oxygen conditions. Proliferation of such cells, which tend to resist chemotherapy and help tumors spread, are considered a major roadblock to successful cancer treatment.

PNAS, Mar-2016; 122437-RP-12-090-01-COUN

– Johns Hopkins Medicine

Weight Loss Surgery Beats Diet at Inhibiting Breast Cancer, Study Finds

Weight loss surgery was more effective than a low-fat diet at reversing the cancer-promoting effects of chronic obesity in mice, according to a study led by UNC Lineberger Comprehensive Cancer Center researchers. The preliminary findings will be presented at the 2016 American Association of Cancer Research Annual Meeting in New Orleans.

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AACR Annual Meeting, April-2016

– University of North Carolina Health Care System

Weight Loss Amount Is More Important Than Diet Type in Reversing Obesity-Cancer Link, UNC Study Finds

Researchers with the UNC Lineberger Comprehensive Cancer Center examined whether weight loss via four different diets was linked to reduced tumor growth in laboratory models of breast cancer. Their preliminary findings will be presented tat the 2016 American Association for Cancer Research Annual Meeting in New Orleans.

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AACR Annual Meeting, April-2016

– University of North Carolina Health Care System

BIDMC Researchers Discover Early Indicators of Pancreatic Cancer

Pancreatic cancer, the fourth leading cause of cancer death in the United States, is often diagnosed at a late stage, when curative treatment is no longer possible. A team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has now identified and validated an accurate 5-gene classifier for discriminating early pancreatic cancer from non-malignant tissue. Described online in the journal Oncotarget, the finding is a promising advance in the fight against this typically fatal disease.

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– Beth Israel Deaconess Medical Center

Penn Studies Show High Out-of Pocket Costs Limit Access to Lifesaving Specialty Drugs

“Specialty drugs” have become important treatment options for many serious and chronic diseases, and in some conditions like cancer they represent the only chance for long-term survival. But, insurers increasingly require patients to share the high costs of these medications. Two new studies led by researchers at the Perelman School of Medicine at the University of Pennsylvania have found evidence that such cost-sharing arrangements are associated with significant reductions in access to these drugs. Both papers are published online in the American Journal of Managed Care.

American Journal of Managed Care

– Perelman School of Medicine at the University of Pennsylvania

Study Uncovers Genetic Differences for Kidney Cancer That May Contribute to Survival Disparity in African-Americans

A University of North Carolina Lineberger Comprehensive Cancer Center-led study has identified genetic differences in tumors of African-Americans with the most common type of kidney cancer compared with whites.

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JAMA Oncology, March - 2016

– University of North Carolina Health Care System

Microneedle Patch Delivers Localized Cancer Immunotherapy to Melanoma

Biomedical engineering researchers have developed a technique that uses a patch embedded with microneedles to deliver cancer immunotherapy treatment directly to the site of melanoma skin cancer. In animal studies, the technique more effectively targeted melanoma than other immunotherapy treatments.

Nano Letters, Mar-2016

– North Carolina State University

Self-Repairing Cancer Cells Future of Cancer Treatments

A research group at Cornell University has been studying cancer cells' ability to migrate through to tight spaces and self-repair to develop both treatment and diagnostic solutions for the millions of people who deal with cancer every day.

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– Cornell University

Parents Wary of Online Doctor Ratings, Subset of E. coli Linked to Deadly Disease in Premmies, New Campaigns to Prevent Poisonings, Early Intervention Can Improve Cognitive Delays in Low-Income Children, and more in the Children's Health News Source

Get the latest research and features in the field of children's health and pediatrics, including vaccinations, abuse, premature births, mental health, autism and more in the Newswise Children's Health News Source.

– Newswise

The History and Future of Cancer Immunotherapy

Immunotherapy is currently revolutionizing cancer treatment and, according to Axel Hoos, M.D., Ph.D., has the potential to improve patient outcomes significantly in the future. Dr. Hoos leads one of the Cancer Research Institute’s (CRI) programs—the Cancer Immunotherapy Consortium (CIC)—that played an important role in enabling early immunotherapy trials to succeed. In a paper published in Nature Reviews last week, he laid out the current immunotherapy development paradigm, as well as his strategic vision to optimize the implementation of next generation immunotherapies.

Nature Reviews

– Cancer Research Institute

Model of Tumor Spreading May Help Doctors Pinpoint Best Treatment

Scientists at the Wake Forest Institute for Regenerative Medicine have invented a “metastasis-on-a-chip” system believed to be one of the first laboratory models of cancer spreading from one 3D tissue to another. They hope the technology can one day be used to see how an individual patient’s tumor responds to potential treatments and to learn if and where the tumor is likely to spread.

Biotechnology Bioengineering

– Wake Forest Baptist Medical Center

Build Lung Cancer Screening Programs That Grow, Evolve

Radiologists can get “the right stuff” to build effective multidisciplinary teams and to advance the quality and effectiveness of lung cancer screening programs at ACR 2016 —The Crossroads of Radiology®.

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– American College of Radiology (ACR)

Why Do Sunbathers Live Longer Than Those Who Avoid the Sun?

New research looks into the paradox that women who sunbathe are likely to live longer than those who avoid the sun, even though sunbathers are at an increased risk of developing skin cancer.

Journal of Internal Medicine

– Wiley


TESARO and MD Anderson Announce Immuno-Oncology Collaboration and Exclusive License

TESARO, Inc., an oncology focused biopharmaceutical company, and the Institute for Applied Cancer Science at The University of Texas MD Anderson Cancer Center today announced an exclusive collaboration to discover and develop small molecule product candidates against undisclosed immuno-oncology targets.

(Embargo expired on 29-Mar-2016 at 08:05 ET)

– University of Texas M. D. Anderson Cancer Center

Embracing Vice President Biden’s Moonshot Call to Cure Cancer, Johns Hopkins Launches Immunotherapy Center with $125 Million Gift From Michael Bloomberg, Sidney Kimmel and Others

A new institute studying immunology with the potential to eventually end all forms of cancer was announced today at Johns Hopkins by Vice President Joe Biden, Michael R. Bloomberg and more than a dozen additional supporters of this initiative.

– Johns Hopkins Medicine

Niesha L. Griffith Receives 2016 Award of Excellence at 12th Hematology Oncology Pharmacy Association Annual Conference, Atlanta, GA

The Hematology/Oncology Pharmacy Association (HOPA) awarded Niesha L. Griffith, MS RPh FASHP, the 2016 Award of Excellence at the 12th HOPA Annual Conference on March 17 in Atlanta. This prestigious award recognizes a member who has made a significant, sustained contribution to or provided excellent leadership in improving or supporting hematology/oncology pharmacy.

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– Hematology Oncology Pharmacy Association

IMP-Researcher Johannes Zuber Wins German Cancer Prize

Johannes Zuber, group leader at the Research Institute of Molecular Pathology (IMP) in Vienna, received the German Cancer Prize 2016 in the category of experimental cancer research.

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– IMP - Research Institute of Molecular Pathology

Meridian Health Foundation Premiers BuildingHOPE Benefit

Meridian Health Foundation’s first annual BuildingHOPE Benefit will take place on Friday, May 13, 2016 at Eagle Oaks Golf & Country Club in Farmingdale, NJ. The event, formerly known as the Sweetheart Ball for its February timeframe, has been moved to May and will benefit oncology research through Meridian Cancer Care.

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– Meridian Health

MD Anderson Patient Endowment Marks Silver Anniversary

The University of Texas MD Anderson Cancer Center’s Volunteer Endowment for Patient Support (VEPS), which funds patient-focused programs, celebrates its 25th anniversary this year.

– University of Texas M. D. Anderson Cancer Center

Making Cancer History®: Free Seminar Comes to Austin

The University of Texas MD Anderson Cancer Center brings its signature Making Cancer History® seminar to Austin, 11:30 a.m. to 1 p.m., Tuesday, April 19, at the AT&T Executive Education and Conference Center, 1900 University Ave.

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– University of Texas M. D. Anderson Cancer Center

Higher Education Events

The Real Superheroes Run Among Us: Fun Run to Raise Money for Cancer Research

The second annual Kevin Rudi Superhero 5K Fun Run will start and end by the Memorial Stadium Field House in Las Cruces. Money raised for sarcoma research will benefit The University of New Mexico Comprehensive Cancer Center. Matthew Duran says, “He’s my superhero. He never gave up. He fought till his last day.”

– University of New Mexico Comprehensive Cancer Center

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