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Newswise Special Wire
Tuesday, August 30, 2016

Public edition |

Newswise Cancer Research Wire for 30-Aug-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

UofL Research Shows Presence of Children in the Home Did Not Motivate Parents to Test for Radon, Secondhand Smoke

Luz Huntington-Moskos, Ph.D., R.N., C.P.N., UofL School of Nursing assistant professor, recently published findings in the journal Public Health Nursing that show the presence of children in the home did not motivate parents to test and mitigate for ...

– University of Louisville

Public Health Nursing, July 2016

Breast cancer researchers look beyond genes to identify more drivers of disease development

Breast cancer researchers have discovered that mutations found outside of genes that accumulate in estrogen receptor positive breast tumours throughout their development act as dominant culprits driving the disease....

– University Health Network (UHN)

Nature Genetics, Aug-2016

Embargo expired on 29-Aug-2016 at 11:00 ET

Vitamin C May Boost Effectiveness of Acute Myeloid Leukemia Treatment

A simple adjustment to patients’ therapeutic regimen may improve the effectiveness of the standard epigenetic treatment for myeloid dysplastic syndrome (MDS) and acute myeloid leukemia (AML)....

– Van Andel Research Institute


Study Uncovers Molecular Switch That May Sensitize Triple-Negative Breast Cancers to Immunotherapy

University of Colorado Cancer Center investigators unpack the mechanism of investigational drug, AMPI-109, showing its inactivation of PRL-3 flips an important switch on triple-negative breast cancer....

– University of Colorado Cancer Center

Oncogenesis; P30 CA046934

Lay Educators Help Boost Colorectal Screening Rates in Hmong

Hmong Americans are more likely to understand the importance of colorectal cancer screening and to get screened when they’re provided information by specially trained Hmong lay health educators, new research from UC Davis has found....

– UC Davis Comprehensive Cancer Center


Embargo expired on 26-Aug-2016 at 09:00 ET

New Research Reveals Cancers Need a 'Perfect Storm' of Conditions to Develop

SCIENTISTS have demonstrated for the first time the 'perfect storm' of conditions that cells need to start forming cancer, helping to explain why some organs are more susceptible to developing the disease, according to a new study published in Cell t...

– Cancer Research UK


Researchers Find a New Way to Identify and Target Malignant Aging in Leukemia

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute...

– University of California San Diego Health Sciences

Cell Stem Cell

Study Finds Links Between Physicians Setting Cancer Care Guidelines and Drug Industry

University of North Carolina LIneberger Comprehensive Cancer Center researchers say the finding of a high prevalence of financial relationships among authors who helped develop a leading set of cancer care guidelines in the United States lays the fou...

– University of North Carolina Health Care System

JAMA Oncology, August -2016

Embargo expired on 25-Aug-2016 at 11:00 ET

Researchers Question Process for Reviewing Coverage of ‘Off Label’ Cancer Drug Use

In a paper published online by the Journal of the American Medical Association, UNC Lineberger Comprehensive Cancer Center physician-researchers raised concerns that there are inconsistencies between the five reference guides, or compendia, that the ...

– University of North Carolina Health Care System

JAMA, August, 2016

Embargo expired on 25-Aug-2016 at 11:05 ET

Stem Cell Propagation Fuels Cancer Risk in Different Organs

Experiments reveal the crucial contribution of stem cells to the origins of cancer in different organs. ...

– St. Jude Children's Research Hospital

P01CA96832, R01 and P30CA021765

Embargo expired on 25-Aug-2016 at 12:00 ET

Researchers Identify Possible Pathway to Reboot Immune System After Bone-Marrow Transplants

New research has shown how a cell surface molecule, Lymphotoxin β receptor, controls entry of T-cells into the thymus; and as such presents an opportunity to understanding why cancer patients who undergo bone-marrow transplant are slow to recover th...

– University of Birmingham

Journal of Immunology, Aug-2016

Rutgers Study Could Be First Step to Prevent Fuel Supply That Feeds Cells in Cancer, Diabetes

Rutgers researchers discovered that mTOR responds to decreasing levels of nutrients, acting as “traffic control” to help stabilize cells as nutrient intake fluctuates. The study is the first to indicate that mTOR actively participates in the proc...

– Rutgers Robert Wood Johnson Medical School


Fused Genes Found in Esophageal Cancer Cells Offer New Clues on Disease Mechanisms

Now, researchers from Case Western Reserve University School of Medicine have characterized structurally abnormal genes in esophageal adenocarcinoma, the findings of which could pave way for developing new biomarkers in this fatal disease. ...

– Case Western Reserve University

Cancer Research, August-2016; K08 CA148980 ; R01 CA204549 ; U01 CA152756 ; U54 CA163060 ; P50 CA150964; P50 CA150964 ; R25T CA094186 ; DK083251...

In Sub-Saharan Africa, Cancer Can Be an Infectious Disease

University of Colorado Cancer Center researcher shows that women who contract malaria while pregnant may have children with an increased risk of Burkitt's lymphoma....

– University of Colorado Cancer Center

Current Opinions in Virology; NIH (CA102667)

Physicist’s DNA Chip Offers Big Possibilities in Cell, Cancer Studies

A University of Texas at Dallas physicist has developed a novel technology that not only sheds light on basic cell biology, but also could aid in the development of more effective cancer treatments or early diagnosis of disease....

– University of Texas at Dallas

Biosensors and Bioelectronics, June 2016

Excess weight linked to 8 more cancer types

There’s yet another reason to maintain a healthy weight as we age. An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (...

– Washington University in St. Louis

New England Journal of Medicine, Aug.

Embargo expired on 24-Aug-2016 at 17:00 ET

Funneling Fundamental Particles, Neutrino Experiments, Physicists Discover 'Apparent Departure From the Laws of Thermodynamics', and More in the Physics News Source Sponsored by AIP

Click here to go directly to the Physics News Source Sponsored by AIP....

– Newswise

NEJM Study: MRI-Guided Focused Ultrasound Effective to Treat Essential Tremor, Most Common Movement Disorder

Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journa...

– University of Maryland Medical Center/School of Medicine

New England Journal of Medicine, Aug 25, 2016

Overcoming Multidrug-Resistant Cancer with Smart Nanoparticles

Multidrug resistance (MDR) is the mechanism by which many cancers develop resistance to chemotherapy. Researchers have developed nanoparticles that simultaneously deliver chemotherapy drugs to tumors and inhibit the MDR proteins that pump the therape...

– National Institute of Biomedical Imaging and Bioengineering

Sci Rep, Feb-2016; ACS Appl Mater Interfaces, Jun-2016

Johns Hopkins Scientists Track Metabolic Pathways to Find Drug Combination for Pancreatic Cancer

Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown cells and mice, Johns Hopkins scientists report that ...

– Johns Hopkins Medicine

Proceedings of the National Academy of Sciences; CA193895, CA169757, DA032470, MH075673, TR001079

Nanovaccine Could Enhance Cancer Immunotherapy, Reduce Side Effects

Researchers have created a nanovaccine that could make a current approach to cancer immunotherapy more effective while also reducing side effects....

– National Institute of Biomedical Imaging and Bioengineering

Nanoscale, issue 8, 2016

Nanoparticle That Mimics Salmonella Counteracts Chemotherapy Resistance, Protein’s Role in Cell Division, A Novel MRI Method, and MORE in the Cancer News Source

Click here to go directly to the Cancer News Source...

– Newswise

Nanoparticle That Mimics Salmonella Counteracts Chemotherapy Resistance

Researchers at the University of Massachusetts Medical School have designed a nanoparticle that mimics the bacterium Salmonella and may help to counteract a major mechanism of chemotherapy resistance....

– National Cancer Institute (NCI) at NIH

Nature Communications

Know Your Risk for Ovarian Cancer

Mount Sinai Experts Share Tips for Ovarian Cancer Awareness Month in September...

– Mount Sinai Health System

Novel MRI Technique Distinguishes Healthy Prostate Tissue From Cancer Using Zinc

A novel MRI method that detects low levels of zinc ion can help distinguish healthy prostate tissue from cancer, UT Southwestern Medical Center radiologists have determined....

– UT Southwestern Medical Center

Proceedings of the National Academy of Sciences

Embargo expired on 22-Aug-2016 at 15:00 ET

A New Roadmap to Navigate Treatment Targets for Advanced Prostate Cancer

Research from investigators at Rutgers Cancer Institute of New Jersey; University of California, Los Angeles; University of California, Santa Cruz and other institutions shows a computational approach examining abnormal “signaling” in clinical pr...

– Rutgers Cancer Institute of New Jersey

Cell, Aug-2016

Mayo Clinic Researchers Investigate Protein’s Role in Cell Division

ROCHESTER, Minn. – In a paper published recently in the journal eLife, Mayo Clinic scientists take a step toward translating the protein BubR1’s function into a potential therapy for cancer....

– Mayo Clinic



New NCCN Imaging Appropriate Use Criteria Published for Eight Cancer Types

NCCN Imaging AUC™ provide a single access point for all oncology imaging recommendations within the NCCN Guidelines; currently, NCCN Imaging AUC™ are available for 20 cancer types....

– National Comprehensive Cancer Network® (NCCN®)

Researcher to Study a Two-Pronged Approach Against Colorectal Cancers

Ellen Beswick, PhD, studies G-CSF, a protein that could be key in attacking cancers of the colon and rectum, and possibly other cancers, too. Beswick was recently awarded a $1.7 M grant to study how G-CSF reduces tumor growth and draws macrophages, T...

– University of New Mexico Comprehensive Cancer Center


Cancer Research Institute to Honor Amgen for Advancing Cancer Immunotherapy Treatments and Patient Education

Nonprofit devoted to cancer immunotherapy will honor the biotech company Amgen for its contributions to cancer immunotherapy treatment and patient education...

– Cancer Research Institute

University of Louisville Faculty Named Editors-in-Chief of Medical Journals

Two faculty from the University of Louisville have been named editors-in-chief of the 'International Journal of Transplantation Research and Medicine' and the 'Journal of Medical Regulation'...

– University of Louisville

Scripps Health and MD Anderson Cancer Center Announce Partnership to Create Clinically Integrated Cancer Program

Scripps Health and The University of Texas MD Anderson Cancer Center have reached a partnership agreement to create Scripps MD Anderson Cancer Center, a comprehensive and clinically integrated cancer care program in San Diego that will provide adult ...

– University of Texas M. D. Anderson Cancer Center

NDSU, Sanford Health Select Human Health Research Grant Recipients

Three research projects have received $250,000 in seed funding from the Sanford Health NDSU Collaborative Seed Grant program. ...

– North Dakota State University

Briefing on Clinical Advances in Focused Ultrasound

A briefing featuring short presentations on key data shared at the 5th International Symposium on Focused Ultrasound. Experts will highlight clinical outcomes and advances in the use of focused ultrasound – a non-invasive therapeutic technology –...

– Focused Ultrasound Foundation

ASTRO Supports Cancer Research by Awarding $36,500 to 44 Scientists and Clinicians Presenting Studies at Its 2016 Annual Meeting

The American Society for Radiation Oncology (ASTRO) has selected 44 cancer researchers and clinicians to receive a total of $36,500 in individual awards for studies being presented at the Society’s annual scientific meeting....

– American Society for Radiation Oncology (ASTRO)

MD Anderson Plans Free Making Cancer History® Seminar in Atlanta

The University of Texas MD Anderson Cancer Center presents it Making Cancer History® Seminar, 11:30 a.m. to 1 p.m. Wednesday, Sept. 21 at the Grand Hyatt Atlanta in Buckhead, 3300 Peachtree Rd. NE. MD Anderson cancer experts will discuss the institu...

– University of Texas M. D. Anderson Cancer Center

Helping Children with Blood Disorders ‘Navigate’ Their Care

Thanks to a two-year, $70,000 commitment from Embrace Kids Foundation, the Comprehensive Sickle Cell Center housed at Rutgers Cancer Institute of New Jersey is expanding to include a Pediatric Sickle Cell and Hemoglobinopathies Nurse Navigator positi...

– Rutgers Cancer Institute of New Jersey

CPRIT Awards $9.6 Million for UTSW Projects in Cancer Treatments, Screening, and Genetics Research

Six new cancer research projects involving treatment, prevention, outreach, and genetics recently received a total of $9.6 million in support from the Cancer Prevention and Research Institute of Texas (CPRIT). ...

– UT Southwestern Medical Center

NCCN Imaging Appropriate Use Criteria to be Integrated into MedCurrent’s OrderWise Platform

Integration of NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™) into MedCurrent’s OrderWise™ platform will provide access to evidence-based imaging recommendations adapted from the NCCN Guidelines®. ...

– National Comprehensive Cancer Network® (NCCN®)

National ‘100 Great Oncology Programs’ List Features UVA

For the fourth consecutive year, the University of Virginia Cancer Center at UVA Medical Center has been honored among 100 hospitals and health systems with great oncology programs by Becker’s Hospital Review, a national healthcare publication. UVA...

– University of Virginia Health System

20 Cancer Care Facilities Receive Outstanding Achievement Award From American College of Surgeons’ Commission on Cancer

The Commission on Cancer (CoC) of the American College of Surgeons (ACS) has granted its mid-year 2016 Outstanding Achievement Award to a select group of 20 accredited cancer programs throughout the United States. Award criteria were based on qualit...

– American College of Surgeons (ACS)

Fourth Annual Basser Global Prize Awarded to Canadian Women’s Cancer Geneticist Steven Narod

The Basser Center for BRCA at Penn’s Abramson Cancer Center has announced the recipient of the 2016 Basser Global Prize. The honor will go to cancer geneticist Steven Narod, MD, FRCPC, PhD (hon), FRSC, director of the Familial Breast Cancer Researc...

– Perelman School of Medicine at the University of Pennsylvania

Professor Receives Funding to Improve Drug Manufacturing Processes

Enrique del Castillo has been awarded $270,568 by the National Science Foundation to develop statistical methods that will improve the formulation and manufacturing of drugs used to treat some of the world’s deadliest diseases....

– Penn State College of Engineering






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