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Newswise Special Wire
Tuesday, September 13, 2016

Public edition |

Newswise Cancer Research Wire for 13-Sep-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Anti-Tumor Immunity Identified with New Ovarian Cancer Treatment Strategy

New research from The Wistar Institute demonstrates how a drug already in clinical trials could be used to boost anti-tumor immunity and cause T-cells to target the cancer directly while minimizing side effects. ...

– Wistar Institute

Cell Reports, Sep-2016

Embargo expired on 13-Sep-2016 at 12:00 ET

Study Examines Survival Outcomes after Different Lung Cancer Staging Methods

In a study appearing in the September 13 issue of JAMA, Jouke T. Annema, M.D., Ph.D., of the Academic Medical Center, Amsterdam, and colleagues examined five-year survival after endosonography vs mediastinoscopy for mediastinal nodal staging of lung ...

– JAMA - Journal of the American Medical Association

Embargo expired on 13-Sep-2016 at 11:00 ET

Mayo Clinic National Health Checkup Finds Cancer Bests Zika as Top Health Care Concern

While Zika remains a hot topic in the news, a new survey by Mayo Clinic reveals that Americans believe the country’s most significant health care challenge is cancer. In fact, the survey findings report “infectious diseases, such as Zika and Ebol...

– Mayo Clinic

Embargo expired on 13-Sep-2016 at 09:00 ET

Michigan, Wisconsin Rivalry Heats Up in the Fight Against Childhood Cancer

The Michigan Wolverines take on the Wisconsin Badgers this fall, and they will be competing for more than a football victory....

– University of Michigan Health System

NUS Scientists Discover Potential Mechanism for Early Detection and Better Treatment of Gastric Cancer

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has found that changes in ribonucleic acid sequences play a major role in the development of gastric cancer. Further research into this nove...

– National University of Singapore


Antibody Discovery Could Help Create Improved Flu Vaccines

Dana-Farber Cancer Institute investigators report they have discovered a type of immune antibody that can rapidly evolve to neutralize a wide array of influenza virus strains – including those the body hasn’t yet encountered....

– Dana-Farber Cancer Institute

Nature Communications

‘Tracking Bugs’ Reveal Secret of Cancer Cell Metabolism

A simple experiment, originally undertaken to test a new methodology, unexpectedly disproved the prevailing notion of cancer metabolism. ...

– Washington University in St. Louis

Nature Chemical Biology

How to Weather the First Week After a Cancer Diagnosis

Mark J. Fesler, M.D., assistant professor of hematology and medical oncology at Saint Louis University Cancer Center says that the anxiety that comes with a positive cancer test can and should be managed....

– Saint Louis University Medical Center

Leukemia Patient Meets Bone Marrow Donor Who Saved His Life

Leukemia survivor Michael Beltrame, a 42-year-old father of three, owes his life to a complete stranger who altruistically donated bone marrow cells for Mr. Beltrame’s successful bone marrow transplant. Mr. Beltrame met his donor for the first time...

– Loyola University Health System

Case for Liquid Biopsies Builds in Advanced Lung Cancer

For patients with advanced lung cancer, a non-invasive liquid biopsy may be a more effective and suitable alternative to the gold standard tissue biopsy to detect clinically relevant mutations and help guide their course of treatment. ...

– Perelman School of Medicine at the University of Pennsylvania


Double Negative Leads to Big Positive Against Bladder Cancer Metastasis

New understanding stops bladder cancer's ability to stop the tumor-suppressing gene RhoDGI2, thus allowing its initial action to proceed....

– University of Colorado Cancer Center

Cancer Cell

Mount Sinai Researchers Identify New Therapeutic Target for Cancer

New research from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai identifies a protein that may be an unexplored target to develop new cancer therapies. The protein, known as kinase suppressor of Ras, or KSR, is a pseudoenzy...

– Mount Sinai Health System

Penn Software Helps to Identify Course of Cancer Metastasis, Tumor "Evolution"

Tumors also differ among patients with the same type of cancer, so how is a physician able to prescribe a tailored regimen for the patient? Researchers developed Canopy, an approach to infer the evolutionary track of tumor cells by surveying two type...

– Perelman School of Medicine at the University of Pennsylvania


Tamoxifen Resistance Linked to High Estrogen Levels in Utero

An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward in human research as about h...

– Georgetown Lombardi Comprehensive Cancer Center

Journal of the National Cancer Institute (JNCI)

Embargo expired on 08-Sep-2016 at 13:00 ET

Study shows how Chinese medicine kills cancer cells

Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China – a Traditional Chinese Medicine – works to kill cancer cells....

– University of Adelaide


Ginger and Chili Peppers Could Work Together to Lower Cancer Risk

For many people, there's nothing more satisfying than a hot, spicy meal. But some research has suggested that capsaicin, the compound that gives chili peppers their kick, might cause cancer. Now researchers show in mouse studies that the pungent comp...

– American Chemical Society (ACS)

Journal of Agricultural and Food Chemistry

Combination Therapy Shows Promise for Chronic Myeloid Leukemia

A study in mice combining two inhibitor drugs for treatment of chronic myeloid leukemia (CML) has revealed potential for not only stopping the disease completely, but also significantly lowering the cost for treatment....

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 07-Sep-2016 at 14:00 ET

Electronic Health Record Data Can Help Determine Highest Risk of Early Death from Chemotherapy in Older Patients with Lymphoma

As published in JNCCN, a new Brown University study of registry data for older patients with diffuse large B-cell lymphoma treated with contemporary immunochemotherapy found opportunities to mitigate early death using key risk factors in decision-mak...

– National Comprehensive Cancer Network® (NCCN®)

Sugar Transforms a Traditional Chinese Medicine Into a Cruise Missile

More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant. A brief review of published research revealed that the extrac...

– Johns Hopkins Medicine

Angewandte Chemie; UL1 TR 001079

New Tumor Analysis Method Identifies High-Risk Prostate Cancer

Scientists at Cedars-Sinai have developed a new way to identify which prostate cancer patients are likely to develop aggressive types of the disease even if their tumors at first appear to be lower risk. The new findings could help physicians prescri...

– Cedars-Sinai

Cancer Research

Fruit Flies Yield Clues on Cancerous Tumor Hotspots

A Florida State University research team, in coordination with a team from Japan, has found that the epithelial tissues that line the surfaces of organs throughout the body intrinsically have hot spots for cancerous tumors. They discovered this b...

– Florida State University

Researchers Find Molecular Link Behind Aspirin’s Protective Powers

Researchers at Duke Health have identified a new mechanism of aspirin’s action that appears to explain the drug’s diverse benefits. ...

– Duke Health

EBioMedicine; RC1GM091083; R01HL109568; R01HL118049

JCAR014 Clinical Data Published in Science Translational Medicine: Patients with Advanced Lymphoma in Remission After T-Cell Therapy

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen ...

– Fred Hutchinson Cancer Research Center

Science Translational Medicine

Clinical Trials and Emerging Research in Radiation Oncology to Be Featured at ASTRO’s Annual Meeting in Boston

The American Society for Radiation Oncology (ASTRO) announced today the press program for its 58th Annual Meeting, which includes multiple reports from phase III clinical trials, researchers from leading institutions in the U.S. and abroad, and exami...

– American Society for Radiation Oncology (ASTRO)

The Mayo Clinic Cancer Center Participates in NCI-MATCH Clinical Trial

ROCHESTER, Minn. — The Mayo Clinic Cancer Center has announced it is participating in the National Cancer Institute’s Molecular Analysis for Therapy Choice clinical trial, also known as NCI-MATCH or study EAY131. The Mayo Clinic Cancer Center is ...

– Mayo Clinic

10 Cancer Moonshot Blue Ribbon Panel Recommendations Embraced by NCI

When 28 distinguished individuals convened earlier this year to help shape the scientific mission at the National Cancer Institute (NCI) of Vice President Joe Biden’s National Cancer Moonshot Initiative, they were given five months to draft guideli...

– University of California San Diego Health Sciences

Mayo Clinic Monthly News Tips, August 2016

Mayo Clinic Monthly News Tips, August 2016...

– Mayo Clinic

New PET Scan for Prostate Cancer Patients

Loyola Medicine is the first center in the Midwest to offer the first effective PET/CT scan for prostate cancer patients. The scan can detect the location and extent of cancer that has recurred after initial treatment. Prostate PET/CT scans can detec...

– Loyola University Health System

UCSF Cancer Researchers Discuss the Value of SU2C Dream Team Collaborations in Advance of Friday's Telecast

On September 9th, millions of people across the United States and Canada are expected to tune into the fifth biennial Stand Up to Cancer broadcast raising money for cancer research. Since 2008, SU2C has raised more than $370 million and dedicates 100...

– UCSF Helen Diller Family Comprehensive Cancer Center

Policy and Public Affairs

Patient and Provider Groups Urge Medicare Not to Undercut Lung Cancer Screening

More than 80 patient advocacy groups, medical associations and health care systems are urging the Centers for Medicare & Medicaid Services (CMS) to abandon drastic low-dose computed tomography (LDCT) lung cancer screening reimbursement cuts in the 20...

– American College of Radiology (ACR)


GW Cancer Center Launches Online Community of Practice for Patient-centered Care

The George Washington University Cancer Center is pleased to announce the launch of the first-ever online Community of Practice for patient-centered cancer care....

– George Washington University

GW Cancer Center Appoints Michael K. Benedict to Serve as Associate Center Director for Administration and Finance

The George Washington University Cancer Center is pleased to announce that Michael K. Benedict, PharmD, has been appointed as the associate center director for administration and finance....

– George Washington University

Orlando Health Bringing New Cancer-Fighting Technology to Central Florida

Orlando Health will soon begin providing a new therapy that allows oncologists to see the tumor they are treating continuously during radiation therapy. It’s a cancer-fighting technology called MRIdian® that will be installed at the new comprehens...

– Orlando Health

AMP to Recognize Eric Lander with 2016 Award for Excellence in Molecular Diagnostics

Eric Lander, PhD, President and Founding Director of the Broad Institute of MIT and Harvard, and Professor of Biology at MIT and Professor of Systems Biology at Harvard Medical School, has earned this year's Award for Excellence in Molecular Diagnost...

– Association for Molecular Pathology

Henry Ford Radiation Oncologist Appointed Chair of ASTRO’s Annual Meeting Scientific Program Committee

Benjamin Movsas, M.D., chair of the Department of Radiation Oncology at Henry Ford Health System, has again been appointed chair of the American Society for Radiation Oncology (ASTRO) Annual Meeting Scientific Program Committee. ...

– Henry Ford Health System

Blue Ribbon Panel Report Garners AACI Endorsement

The Association of American Cancer Institutes (AACI) strongly supports the recommendations of the Cancer Moonshot Blue Ribbon Panel, and thanks the panel’s members who lead AACI cancer centers for their service....

– Association of American Cancer Institutes (AACI)

Higher Education Events

2016 Ruesch Center Policy Briefing: Fighting a Smarter War on Cancer

The Ruesch Center for the Cure of Gastrointestinal Cancers at Georgetown Lombardi Comprehensive Cancer Center hosts its 2016 Cancer Policy Briefing, Wednesday, September 14 from 9:00 to 11:30 a.m. at the Georgetown University Law Center....

– Georgetown Lombardi Comprehensive Cancer Center





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