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Newswise Special Wire
Tuesday, September 20, 2016

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Newswise Cancer Research Wire for 20-Sep-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

New Therapeutic Target for Crohn’s Disease

Research from the Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies a promising new target for future drugs to treat inflammatory bowel disease (IBD). The study, published today in Cell Reports, also indicates that another protein, ...

– Sanford Burnham Prebys Medical Discovery Institute

Cell Reports; NIH R01DK108743; NIH R01CA172025; NIH R01CA192642; 5P30CA030199

Embargo expired on 20-Sep-2016 at 12:00 ET

Scientists Discover Interplay of Yin-Yang Antagonists Vital for Cell Division

UNC School of Medicine scientists discover that a pair of large enzyme complexes attack each other in turn to form a molecular switch, which is essential for cell division....

– University of North Carolina Health Care System

Cell Reports

Embargo expired on 20-Sep-2016 at 12:00 ET

Ludwig Researchers Solve a Mystery of Early Embryonic Development

A Ludwig Cancer Research study published in the current issue of Nature reports a novel technique to map specific chemical (or “epigenetic”) modifications made to the protein packaging of DNA using a small population of cells. Such epigenetic mar...

– Ludwig Cancer Research

Nature, Sept-2016

Fighting Cancer with Sticky Nanoparticles

A team of researchers at Yale found that a treatment using bioadhesive nanoparticles loaded with a potent chemotherapy drug proved more effective and less toxic than conventional treatments for gynecological cancer. ...

– Yale Cancer Center

Molecular Switch Controlling Immune Suppression May Help Turn Up Immunotherapies

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to maximize the effectiveness of anti-cancer immune therapy. The researchers identified a molecular switch that controls immune ...

– University of California San Diego Health Sciences

Nature; Cancer Discovery; Cancer Discovery

Embargo expired on 19-Sep-2016 at 11:00 ET

ASCO, ASTRO and SSO Update Guideline on Postmastectomy Radiotherapy

Three leading national cancer organizations today issued a joint clinical practice guideline update for physicians treating women with breast cancer who have undergone a mastectomy....

– American Society for Radiation Oncology (ASTRO)

A Talk with a Nurse Can Persuade Hospital Patients to Quit Smoking

New research shows that self-reported quit rates among hospital patients more than doubled when nurses and other staff were trained to coach patients on how to stop smoking and to make sure they got the help they needed to make it happen, whether tha...

– Ohio State University

Embargo expired on 16-Sep-2016 at 00:05 ET

Retinoic Acid May Significantly Prevent Lymphedema Development, Experimental Model Suggests

Using newly updated mouse models, USC researchers demonstrated the impactful preventive properties of 9-cis retinoic acid against lymphedema. Currently, there is no cure for lymphedema, a swelling of the extremities that most commonly occurs after tr...

– Keck Medicine of USC

Annals of Surgery, Aug-2016; KL2TR000131; R21HL119583; R01HL121036; 13GRNT17060131

Study: Incisionless Robotic Surgery Offers Promising Outcomes for Oropharyngeal Cancer Patients

A new study from researchers at Henry Ford Hospital finds an incisionless robotic surgery – done alone or in conjunction with chemotherapy or radiation – may offer oropharyngeal cancer patients good outcomes and survival, without significant pain...

– Henry Ford Health System

AAO-HNS Annual Meeting

High-Calcium, Low-Lactose Diet May Reduce Risk of Ovarian Cancer in African-American Women

Research from Rutgers Cancer Institute of New Jersey and and other U.S. health and academic institutions shows a diet high in calcium and low in lactose may reduce the risk of ovarian cancer in African-American women. The work also found sun exposure...

– Rutgers Cancer Institute of New Jersey

British Journal of Cancer, Sept-2016

Nanoparticle Drug Cocktail Could Help Treat Lethal Cancers

A group of scientists from the University of Chicago has developed an ingenious way to spur checkpoint blockade cancer immunotherapy into more potent action. The therapy offers the hope of an effective treatment for intractable metastatic cancers inc...

– University of Chicago

Innovation to Impact: Dr. Lieping Chen and NextCure

Dr. Lieping Chen has launched a startup—NextCure—that is poised to lead to even more breakthrough treatments. ...

– Yale Cancer Center

Seven-Year Study Pays Off with ‘Most Detailed’ Picture of Head and Neck Cancer Stem Cells to Date

"After chemo, PI3K helps the cell shut down and weather the storm. Then when the chemo is gone, PI3K helps cancer stem cells start back up again," says University of Colorado Cancer Center investigator, Antonio Jimeno, MD, PhD....

– University of Colorado Cancer Center

Journal of the National Cancer Institute

Embargo expired on 15-Sep-2016 at 12:00 ET

Taste for Fat

Most cancers have a sweet tooth but—mysteriously—some tumors prefer fat over sugar. Now, a study from Harvard Medical School reveals how these cancers develop their appetite for fat. ...

– Harvard Medical School

Molecular Cell

Embargo expired on 15-Sep-2016 at 12:00 ET

Study Shows Opioid 'Undertreatment' for Patients Dying of Cancer

Many patients who die of cancer receive no or delayed prescriptions for strong opioid medications—the recommended treatment for cancer-related pain, reports a study in PAIN®, the official publication of the International Association for the Study ...

– Wolters Kluwer Health: Lippincott Williams and Wilkins


Computer Program Beats Physicians at Brain Cancer Diagnoses

Researchers at Case Western Reserve University have developed a computer program that uses radiomic features found in routine MRI scans to distinguish between radiation necrosis and recurrent brain cancer. In a comparison, the program was nearly twic...

– Case Western Reserve University

American Journal of Neuroradiology 10.3174/ajnr.A4931

New Phase I Clinical Trials Infusion Center Opens at Smilow Cancer Hospital

The new Phase I Clinical Trial Infusion Center will provide essential options for patients with advanced cancers seeking new therapies when standard treatments are no longer an option....

– Yale Cancer Center

Moffitt Cancer Center Works to Improve Cancer Healthcare Disparities in LGBTQ Community

In August, Moffitt researchers invited LGBTQ academic and advocacy experts from across the country to join them to discuss barriers and opportunities to overcome cancer healthcare disparities in the LGBTQ community. ...

– Moffitt Cancer Center

Study May Help Reassure Women Taking Tamoxifen for Breast Cancer

A study led by Loyola Medicine researchers may help reassure patients who worry the breast cancer drug tamoxifen could increase their risk of uterine cancer....

– Loyola University Health System

Nature npj Breast Cancer

St. Jude Children’s Research Hospital and Sanger Institute, UK Collaborate to Make Data Beautiful

St. Jude Children’s Research Hospital and Sanger Institute agreement makes it easy for any scientist to explore cancer genome data....

– St. Jude Children's Research Hospital

Brain Cancer Survivor Supported by University of Cincinnati Football Team.

Mitch Stone was 11 years old when he was diagnosed with brain cancer. The University of Cincinnati football team "adopted" Mitch and helped support his recovery. Now 18, Mitch is a UC student rooting on the Bearcats from the sidelines. ...

– Cincinnati Children's Hospital Medical Center

ASTRO Encourages Prostate Cancer Patients to Weigh Long-Term Impact of Treatment Options with Their Doctors

In light of the findings from the Prostate Testing for Cancer and Treatment (ProtecT) trial published today in the New England Journal of Medicine, the American Society for Radiation Oncology (ASTRO) would like to congratulate the authors and investi...

– American Society for Radiation Oncology (ASTRO)

New Paper From University Hospitals Seidman Cancer Center Provides Insights for Music Therapy in Surgical Area

A new paper describes how music therapists and perioperative nurses worked together to establish a music therapy program during a two-year clinical study looking at the effects of live and recorded music on the anxiety levels of patients undergoing b...

– University Hospitals Cleveland Medical Center

Fusion Targeted Prostate Biopsy Proves More Accurate in Diagnosis of Prostate Cancer

New research confirms that an innovative procedure combining MRI and ultrasound to create a 3D image of the prostate can more accurately locate suspicious areas and help diagnose whether it’s prostate cancer....

– UT Southwestern Medical Center

Yale Cancer Center Researchers Identify New T cell Subsets with Potential to Improve Cellular Therapy for Cancer

A Yale Cancer Center research team has identified that two genes, NR4A1 and ABC transporters, mark a distinct subset of quiescent T cells within human tissues, and have developed methods to mobilize them into circulation for potential application in ...

– Yale Cancer Center

Journal of Clinical Investigation

Potent Anti-Cancer Molecule in Tumors Can Be Reawakened

In mice studies, targeting the SET protein revives p53, a potent tumor suppressor, and prevents cancer growth....

– Columbia University Medical Center

Skull Base Surgeons Help Pioneer Method of Extracting Tumors From Ear Canal

A surgical team at UT Southwestern Medical Center is helping to pioneer a new minimally invasive procedure that extracts vertigo-inducing tumors from the inner ear without having to remove a large piece of skull, as is usually required....

– UT Southwestern Medical Center

Mother with Hearing Loss Discovers Rare Tumor, Helps Pioneer Surgery Through Ear

Ana Placencia stretched in bed after waking up one Saturday morning, when suddenly the hearing in her left ear became muffled....

– UT Southwestern Medical Center

Tobacco Industry Tactics Influential in E-Cigarette Policy

By employing the same tactics it used to drive policymaking from the 1970s-1990s, the tobacco industry has become successful in influencing pro-industry e-cigarette laws at the state level, according to a UCSF study published in the September issue o...

– UCSF Helen Diller Family Comprehensive Cancer Center

Milbank Quarterly

MD Anderson Receives $19 Million in CPRIT Funding for Recruitment and Research

The University of Texas MD Anderson Cancer Center was awarded $19 million this week from the Cancer Prevention and Research Institute of Texas (CPRIT) for the recruitment of four cancer scientists and research facility funding. ...

– University of Texas M. D. Anderson Cancer Center

Policy and Public Affairs

Researchers Say to Conquer Cancer You Need to Stop It Before It Becomes Cancer

In a Perspective piece published this week in PNAS, cancer researchers from across the country, including faculty at University of California San Diego School of Medicine and Moores Cancer Center, write that a greater emphasis on immune-based prevent...

– University of California San Diego Health Sciences



NIH Selects Sanford for Grant to Move Cancer Research to Clinical Trials

CoBRE award tops $11 million over five years...

– Sanford Health


NCCN Imaging Appropriate Use Criteria to be Integrated into New Century Health’s Oncology Clinical Decision Support Platform

Integration of NCCN Imaging Appropriate Use Criteria (NCCN Imaging AUC™) into New Century Health’s clinical decision support platform will expand national use of evidence-based imaging recommendations adapted from the NCCN Guidelines®. ...

– National Comprehensive Cancer Network® (NCCN®)

Nationally-Recognized Pulmonary Physician, Epidemiologist to Discuss Tobacco and Health

Jonathan Samet, M.D., M.S. of the University of Southern California Keck School of Medicine, will tackle the issue of tobacco and health, explaining how solid research can drive gains in public health. ...

– University of Louisville

ACR Supports Congressional Opposition to Medicare Lung Cancer Screening Cuts

The American College of Radiology applauds members of the House Ways and Means Committee for standing against planned cuts to Medicare reimbursement for low-dose computed tomography (LDCT) lung cancer screening. ...

– American College of Radiology (ACR)

More Than 1,300 Leading Pathologists to Collaborate About Immunotherapy Strategies at CAP Annual Meeting

Leading pathologists will collaborate in Las Vegas to discuss the specialty's role in the promising area of immunotherapy, as well as several other health care issues at the annual meeting of the College of American Pathologists....

– College of American Pathologists (CAP)

New Huntsman Cancer Institute Center for HOPE Focuses on Underserved Populations

The Huntsman Center for Health Outcomes and Population Equity (HOPE) will focus on discovering new ways to prevent and treat cancer among underserved populations....

– University of Utah Health Sciences

The Rexall Onewalk to Conquer Cancer Announces $6.5 Million Raised as Annual Cancer Fundraiser Commences in Toronto

The Rexall OneWalk to Conquer Cancer announced 3,555 participants raised $6.5 million for Princess Margaret Cancer Centre as the event commenced on Saturday....

– University Health Network (UHN)

Higher Education Events

MD Anderson and Rice University Welcome Vice President Biden to Houston for 54th Anniversary of President Kennedy Moonshot Speech

The University of Texas MD Anderson Cancer Center is pleased to welcome Vice President Joe Biden to Houston and the historic site where 54 years ago President John F. Kennedy delivered his speech about going to the moon, which inspired generations to...

– University of Texas M. D. Anderson Cancer Center

Expert Pitch

Trace Elements: Innovative Biopsy Programs Map How Cancer Spreads

– Yale Cancer Center

Yale Cancer Center Expert available to speak on AACR 2016 Cancer Progress Report: Research is Saving Lives

– Yale Cancer Center

Yale Cancer Center Expert Available to Speak on AACR Cancer Progress Report: Research Is Saving Lives

– Yale Cancer Center

Treating Skin Cancer Using the Body's Immune System

– Yale Cancer Center





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