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Newswise Special Wire
Wednesday, October 12, 2016

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Newswise Cancer Research Wire for 12-Oct-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

A Common Nerve Protein Elevated in Aggressive Neuroblastomas

A protein produced by nerve cells appears to be elevated in the blood of those with an aggressive form of neuroblastoma. The finding could potentially lead to a prognostic test for the disease or be used to monitor its progress....

– Georgetown University Medical Center

American Journal of Pathology DOI: 10.1016/j.ajpath.2016.07.019

Embargo expired on 12-Oct-2016 at 04:00 ET

New Findings Published Today in Nature Challenge Current View of How Pancreatic Cancer Develops

Researchers in the multidisciplinary PanCuRx research initiative at the Ontario Institute for Cancer Research (OICR) and University Health Network’s Princess Margaret Cancer Centre, led by Dr. Faiyaz Notta and Dr. Steven Gallinger, today published ...

– Ontario Institute for Cancer Research


New Model for Understanding Myeloma

To develop new approaches to cancer prevention, scientists have attempted to grow tumor cells from precursor states in animal models. ...

– Yale Cancer Center

MD Anderson and HISD Partner for Youth Tobacco Prevention Program

The University of Texas MD Anderson Cancer Center and the Houston Independent School District (HISD) have reached a first-of-its-kind agreement to provide access to an evidence-based, youth-oriented tobacco prevention and cessation program for all 11...

– University of Texas M. D. Anderson Cancer Center

Community Outreach May Reduce the Risk of Liver Cancer

Trained community partners ensure follow-through on vaccination against hepatitis B virus (HBV)....

– Thomas Jefferson University

UGA Research on Common Bacterium Opens Door to Fighting Gastric Cancer

A common bacterium that more than half of people have in their gut can use hydrogen gas present in the gastrointestinal tract to inject a cancer-causing toxin into otherwise healthy cells, according to a recently published study led by University of ...

– University of Georgia

Technique May Identify Patients with Fast-Progressing Fibrosis in Nonalcoholic Fatty Liver Disease

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states —...

– University of California San Diego Health Sciences


Yale Researchers Find Genes Behind Aggressive Ovarian and Endometrial Cancers

In a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments....

– Yale Cancer Center

Combination Therapy Shows Promise in Fighting Neuroblastoma

A study by a multidisciplinary team of researchers from Children’s Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinato...

– Children's Hospital Los Angeles Saban Research Institute

5P01 CA81403-15 ; 1R01CA182633-01

UCLA Health Prepares to ‘Light the Night’ at Evening Walk to Benefit Blood-Cancer Research, Patients


– University of California, Los Angeles (UCLA), Health Sciences

Employees at an Alabama University Rally Around One of Their Own Fighting Breast Cancer

Almost 100 people have signed up for the annual Komen Race for the Cure in honor of Physical Medicine and Rehabilitation’s Yvonne Akins, a mentor and friend to many at UAB for 42 years. ...

– University of Alabama at Birmingham

Researchers Identify Novel Mechanism in Combination Drug Therapy for Acute Myeloid Leukemia, Other Cancers

Researchers have discovered a novel mechanism in a combination drug therapy that shows potential as a new approach for treating acute myeloid leukemia (AML) and many other cancers. When combined, these agents cause interactions that significantly dis...

– University of Maryland Medical Center/School of Medicine

Cancer Cell, October 10, 2016

Embargo expired on 10-Oct-2016 at 12:00 ET

MD Anderson Study Finds Significant Cost Differences Between Breast Cancer Chemotherapy Regimens

Costs associated with different breast cancer chemotherapy regimens can vary significantly, regardless of effectiveness, according to new research from The University of Texas MD Anderson Cancer Center. Understanding cost differences can help guide i...

– University of Texas M. D. Anderson Cancer Center

2016 American Society of Clinical Oncology Annual Meeting

Embargo expired on 10-Oct-2016 at 00:05 ET

Research Uncovers Defender Against Cancer-Promoting Liver Damage

The liver reacts to chronic injury by walling it off with scar tissue and calling in immune cells with inflammatory signals. If cancer arises, the resulting inflammation then stokes tumor progression. Scientists at the Sanford Burnham Prebys Medical ...

– Sanford Burnham Prebys Medical Discovery Institute

Cancer Cell, Oct-2016; 5P30CA030199; R01DK108743; R01CA172025; R01CA192642

Embargo expired on 10-Oct-2016 at 12:00 ET

New Online App May Help Doctors Predict Risk of Breast Cancer Recurrence

Researchers led by Johns Hopkins Kimmel Cancer Center scientists report they have developed a free web-based app that could take some of the guesswork out of decisions to order an additional and costly molecular test for assessing risk for recurrence...

– Johns Hopkins Medicine

Journal of Clinical Oncology; CA006973, SAC110053, KG 110094

Embargo expired on 10-Oct-2016 at 16:00 ET

Study of Ramucirumab Plus Pembrolizumab Shows Promise in NSCLC

In a phase I clinical trial, patients with previously treated advanced non-small cell lung cancer (NSCLC) have showed initial response and disease control from the drug combination of ramucirumab and pembrolizumab. Roy S. Herbst, MD, PhD, Chief of M...

– Yale Cancer Center

European Society for Medical Oncology Congress, Abstract 2428

Embargo expired on 10-Oct-2016 at 03:30 ET

UHN Research Team Maps Genomic Landscape of Schwannoma Tumours

Researchers from the University Health Network have described the genomic landscape of schwannomas in a paper published online today in Nature Genetics. Schwannomas are one of the most common posterior fossa brain tumours and the most common spinal t...

– University Health Network (UHN)

Precision Medicine Cancer Treatments Focus of Sanford Study

Sequencing tools analyze unique genetic information...

– Sanford Health

Harvest for Health Expands Breast Cancer Study, Looks for New Participants Across Alabama

UAB researchers want to introduce Alabama cancer survivors to a new kind of therapy — gardening....

– University of Alabama at Birmingham

Ribociclib Improves Progression-Free Survival for Women with Metastatic Breast Cancer

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, ribociclib, in combination with the aromatase inhibitor letrozole, dramatically improved progression-free survival (PFS) of post-menopausal wome...

– University of Texas M. D. Anderson Cancer Center

New England Journal of Medicine

Embargo expired on 08-Oct-2016 at 02:15 ET

Upstate Medical University Research Provides Insight Into Cause of Rare Blood Cancer

In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice. The findings create a new pat...

– SUNY Upstate Medical University

New Tool for Cancer Patients Measures the Stress of Expenses

A team of cancer specialists and health economists have developed a tool that can measure a patient’s risk for, and ability to tolerate, the financial stress associated with treatment....

– University of Chicago Medical Center

Cancer, October 2016

Food-Poisoning Bacteria May Be Behind Crohn’s Disease

People who retain a particular bacterium in their gut after a bout of food poisoning may be at an increased risk of developing Crohn’s disease later in life, according to a new study led by researchers at McMaster University....

– McMaster University

PLOS Pathogens

African-American and Hispanic Men Less Likely to Get Treatment for Prostate Cancer, Even with High-Risk Disease

African-American and Hispanic men in the United States are less likely to receive therapy for prostate cancer compared to Caucasian men — even when they have more aggressive disease, according to new research from Roswell Park Cancer Institute and ...

– Roswell Park Cancer Institute


UV Light Robots Cut C. Diff Transmissions by 25 Percent on Cancer Patient Floors, Penn Study Finds


– Perelman School of Medicine at the University of Pennsylvania

Charles S. Fuchs to Lead Yale Cancer Center and Smilow Cancer Hospital

After an extensive national search, Smilow Cancer Hospital and Yale Cancer Center (YCC) have announced that Charles S. Fuchs, MD, MPH, will become the new YCC director and physician-in-chief at Smilow Cancer Hospital, effective Jan. 1, 2017....

– Yale Cancer Center

UT Southwestern Researchers Find Use of PSA for Prostate Screening Unaffected by Changes in Screening Guidelines

Controversy over prostate cancer screening guidelines that discourage use of PSA tests did not significantly reduce use of the test, a five-year review of more than 275,000 visits at UT Southwestern Medical Center showed....

– UT Southwestern Medical Center

Cancer, Sept-2016

Working Night Shifts Unlikely to Increase Breast Cancer Risk

New research has found that working night shifts has little or no effect on a woman's breast cancer risk despite a review in 2007 by the International Agency for Research on Cancer (IARC) classifying shift work disrupting the 'body clock' as a probab...

– Cancer Research UK

Journal of the National Cancer Institute

Reactome Announces Annotation and Release of 10,000th Human Protein

The European Bioinformatics Institute (EMBL-EBI), the New York University School of Medicine and the Ontario Institute for Cancer Research (OICR) today announced a major milestone in the Reactome project: the annotation and release of its 10,000th hu...

– Ontario Institute for Cancer Research

Strange 'Chimeras' Defy Science's Understanding of Human Genetics

The human genome is far more complex than thought, with genes functioning in an unexpected fashion that scientists have wrongly assumed must indicate cancer, research indicates. ...

– University of Virginia Health System

Trends in Cancer

Medical Societies, Advocacy Groups Develop Genetics Toolkit

The Society of Gynecologic Oncology (SGO) convened experts from the American College of Obstetricians and Gynecologists (ACOG), National Society of Genetic Counselors, Bright Pink and Facing Our Risk of Cancer Empowered (FORCE), to develop the SGO Ge...

– Society of Gynecologic Oncology

Embargo expired on 05-Oct-2016 at 16:00 ET

Cancer Treatment as a Double-Edged Sword

Findings by cancer researchers at the Technion-Israel Institute of Technology shed new light on why treated cancers recur. The discovery could provide the key for reducing recurrence, and allow anti-cancer drugs to do their intended work. ...

– American Technion Society

Journal of Pathology

Frontline PARP Inhibitor Shrinks Tumors in BRCA-Positive Breast Patients

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of Texas MD Anderson Cancer Cent...

– University of Texas M. D. Anderson Cancer Center

National Cancer Institute Awards Major Contract to Southern Research

Southern Research has been awarded a five-year IDIQ contract with a potential value of $19 million from the National Cancer Institute (NCI) to study the preclinical toxicology of new drugs that are under development for treatment of cancer....

– Southern Research

Allison To Receive 2016 AACI Distinguished Scientist Award

The Association of American Cancer Institutes will present the AACI Distinguished Scientist Award to James P. Allison, PhD, on October 24, during the 2016 AACI/CCAF Annual Meeting, in Chicago....

– Association of American Cancer Institutes (AACI)

The Medical Minute: Incidence of Thyroid Cancer on the Rise

The incidence of thyroid cancer has tripled in the past three decades, yet the reason for this is not clear....

– Penn State Health Milton S. Hershey Medical Center

Personal Experience as Catalyst, Noted Philanthropist Helps Underserved Women Learn More About Breast Cancer

After her own experience surviving breast cancer, philanthropist Beatrice Welters wanted to “pay it forward” -- and help educate other women about breast cancer and the importance of early detection. And she is doing just that -- through a new p...

– NYU Langone Medical Center

The Incredible Shrinking Particle Accelerator

A new data analysis/visualization toolkit developed at Lawrence Berkeley National Laboratory is designed to help speed particle accelerator research and design by enabling in situ visualization and analysis of accelerator simulations at scale....

– Lawrence Berkeley National Laboratory

IEEE Computer Graphics and Applications, May-June 2016

Roswell Park Team Validates 10 Years of Outcomes Data for Bladder Cancer Surgeries

BUFFALO, N.Y. — What are the factors that add up to the best outcomes for patients who have surgery to treat cancer? Looking for a better way to measure quality of care and share best practices in surgical oncology, a team from Roswell Park Cancer ...

– Roswell Park Cancer Institute

UC San Diego Health Joins Precision Medicine Initiative to Tackle Pancreatic Cancer

Physician-scientists with Moores Cancer Center at UC San Diego Health have been leading the way in pancreatic cancer care by investigating new therapies as well as offering innovative clinical trials and the latest treatments with a personalized medi...

– University of California San Diego Health Sciences

Fred Hutch Selected to Join National Effort to Transform Treatment for Pancreatic Cancer Patients

Today the Pancreatic Cancer Action Network announced Precision Promise, the first large-scale precision medicine trial designed to transform outcomes for patients with pancreatic cancer by tailoring their treatment to their cancer’s unique molecula...

– Fred Hutchinson Cancer Research Center

NYU Lutheran’s Breast Surgery Program Bringing Top Cancer Care to Brooklyn

NYU Lutheran Medical Center continues to advance cancer care in Brooklyn—and a talented new breast surgeon, Janet Yeh, MD, is helping to lead the way. ...

Expert Available

– NYU Lutheran Medical Center


Houston Methodist Receives Nearly $4 Million From U.S. Defense Department to Combat Lethal Breast Cancer

HOUSTON-(Oct. 11, 2016)–Scientists at Houston Methodist received support from the U.S. Department of Defense (DoD) to reprogram immune cells to attack triple negative breast cancer, the most lethal form of the disease. The DoD awarded Rongfu Wan...

– Houston Methodist


College of American Pathologists Teams Up with CVS Health to Expand “See, Test & Treat®” in Texas

CAP Foundation and CVS Health team up to hold three See, Test & Treat events for underserved Texas women...

– College of American Pathologists (CAP)

Case Western Reserve Researcher Receives Major Federal Grant to Test Novel Treatments for Cystic Fibrosis and Severe Asthma

Benjamin Gaston, MD, a pediatric pulmonologist and researcher at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies & Children’s Hospital, has received a five-year, $13.3 million federal grant to develop opt...

– Case Western Reserve University


Multi-Million-Dollar Research Effort Aims to Cripple Cancer’s Deadly Ability to Spread

Supported by a $9 million grant from the National Cancer Institute, a diverse team led by Johns Hopkins researchers has begun looking for new ways to attack one of the scariest traits of this disease: its frequent refusal to stay in one place....

– Johns Hopkins University

Dr. Nancy Davidson of U Pitt to Lead Fred Hutch / University of Washington Cancer Consortium

Fred Hutchinson Cancer Research Center today announced that Dr. Nancy E. Davidson, director of the University of Pittsburgh Cancer Institute, has accepted the position of executive director of the Fred Hutch / University of Washington Cancer Consorti...

– Fred Hutchinson Cancer Research Center

Grant for Cancer Research Means More Cancer Drugs in the Pipeline Faster

Dr. Jung-Hee Woo, director of Baylor Scott & White’s Central Texas cancer research facility, has been awarded a $3.56 million grant from the Cancer Prevention and Research Institute of Texas (CPRIT). The grant will support Baylor Scott & White Heal...

– Baylor Scott and White Health

Michigan Breast Cancer Researcher Receives $600,000 Grant From Susan G. Komen for Genetics Research

Susan G. Komen® awarded Lisa A. Newman, M.D., director of the Breast Cancer Center at Henry Ford Health System, with more than $600,000 in new funding for breast cancer genetics research. ...

– Henry Ford Health System

Clarivate Analytics and Georgetown University Named a USPTO Cancer Moonshot Challenge Winner

Clarivate Analytics announced its third place win with Georgetown University in the USPTO Cancer Moonshot Challenge held by the U.S. Commerce Department’s United States Patent and Trademark Office. ...

– Georgetown Lombardi Comprehensive Cancer Center

Case Western Reserve University Researchers Receive Funding for Promising Childhood Cancer Research

Two Case Western Reserve University School of Medicine researchers are receiving new funding from California-based St. Baldrick’s Foundation for promising childhood cancer research....

– Case Western Reserve University

Molecular Biologist Christine Mayr of Sloan Kettering Institute Honored with Prestigious NIH Director’s Pioneer Award

Molecular biologist Christine Mayr, MD, PhD, of Memorial Sloan Kettering’s (MSK) Sloan Kettering Institute (SKI) is one of the 2016 recipients of the prestigious National Institutes of Health (NIH) Director’s Pioneer Award. Established in 2004, t...

– Memorial Sloan Kettering Cancer Center

Milken Institute School of Public Health Receives $2.6 Million Grant to Study Cervical Cancer Prevention Strategies in Peruvian Amazon

The Milken Institute School of Public Health at the George Washington University (Milken Institute SPH) today announced receiving a $2.6 million award from the National Cancer Institute to develop cervical cancer prevention strategies in the Loreto r...

– George Washington University

Higher Education Events

Bikers Ride for Breast Cancer Awareness

The Turquoise Trail Harley Owner’s Group will end its second annual “Pink Your Ride — Motorcyclists Increasing Awareness (MIA)” ride at The University of New Mexico Comprehensive Cancer Center. The Turquoise Trail Chapter chose to join the Pe...

– University of New Mexico Comprehensive Cancer Center

Expert Pitch

Yale Expert Can Comment on New Phase I Clinical Trial for NSCLC

– Yale Cancer Center

On Deadline for a Breast Cancer Awareness Month Piece? Try One of Our Experts.

– Florida State University





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