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Newswise - News for Journalists
Newswise Special Wire
Tuesday, October 25, 2016

Public edition |

Newswise Cancer Research Wire for 25-Oct-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Terminally Ill Cancer Patients Fare Poorly After Surgery

Patients with disseminated advanced cancer who undergo surgery are far more likely to endure long hospital stays and readmissions, referrals to extended care facilities and death, UC Davis researchers have found....

– UC Davis Comprehensive Cancer Center


Embargo expired on 25-Oct-2016 at 02:00 ET

Structure of Key DNA Replication Protein Solved

Mount Sinai researchers say the protein structure can be used to improve effectiveness of chemotherapy...

– Mount Sinai Health System

Science Advances

Embargo expired on 25-Oct-2016 at 07:00 ET

Precision Medicine Test Helps Guide Breast Cancer Patients’ Chemotherapy Decision

One of the earliest widespread applications of precision medicine in cancer care is helping patients and physicians decide whether chemotherapy is needed, a new study finds....

– University of Michigan Health System

Cancer; CA163233

Embargo expired on 24-Oct-2016 at 00:05 ET

Genetic Hallmarks of Acute Lymphoblastic Leukemia Subtype Uncovered

St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project team identifies genetic changes underlying a type of B-precursor acute lymphoblastic leukemia...

– St. Jude Children's Research Hospital

Nature Genetics

Embargo expired on 24-Oct-2016 at 11:00 ET

Ludwig Researchers Develop a New Way to Evaluate Aggressiveness of Bladder Cancer

A Ludwig Cancer Research study published in the current issue of Scientific Reports describes a new method and risk model to assess how aggressive a bladder cancer is likely to be. “If confirmed in larger studies, our findings could help physicians...

– Ludwig Cancer Research

Scientific Reports, Oct-2016

Embargo expired on 24-Oct-2016 at 12:00 ET

Tumor Markers Can Reveal Lethality of Bladder Cancers, Guide Treatment

Tumor cells collected during the removal of a cancerous bladder and transplanted into mice with weakened immune systems could help physicians rapidly identify high-risk cancers, determine prognosis and refine the use of biomarkers to personalize care...

– University of Chicago Medical Center

Scientific Reports (Nature), October 24, 2016

Drug Target for Triple-Negative Breast Cancer Found in New Study

A team of researchers led by UC San Francisco scientists has identified a new drug target for triple-negative breast cancer, an aggressive disease subtype that has the poorest outcomes and accounts for as many as one in five cases. The findings are p...

– UCSF Helen Diller Family Comprehensive Cancer Center

Sexual Pain in Women After Cancer Is Common, and Too Often Ignored

Painful sex in women after cancer treatment is relatively common, often treatable and needs to be addressed by medical providers, a UC Davis oncologist and researcher suggests....

– UC Davis Comprehensive Cancer Center

Obstetrics and Gynecology, Oct. 2016

CTASINs as Viable Target for Colon Cancer Therapies, End-of Chromosome Repair in Real Time, Do Risk Factors for Breast Cancer Change with a Woman's Age, and MORE in the Cancer News Source

Click here to go directly to the Cancer News Source...

– Newswise

Study Links Changes in Collagen to Worse Pancreatic Cancer Prognosis

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer. ...

– University of Wisconsin-Madison

Oncotarget Oct 20 2016

Measuring the Forces of Biology

Biology, at the nitty-gritty level of motor proteins, DNA, and microtubules, takes its cue from physics. But while much is known about the biological components that form such cellular structures, researchers like Scott Forth are only beginning to ex...

– Rensselaer Polytechnic Institute (RPI)

For Many Women with Endometrial Cancer, Innovative Treatment at NYU Lutheran Provides Hope

Endometrial cancer expert Ghadir Salame, MD, from NYU Lutheran Medical Center in Brooklyn is helping women in the borough -- and beyond -- address this life-threatening issue through advanced treatment, including robotic-assisted surgery. ...

– NYU Lutheran Medical Center

The Five Questions Every Woman Should Ask Her Doctor About Her Breast Health

An Alabama woman asked her primary care physician one question that may have saved her life — is it time for me to have a mammogram? ...

Expert Available

– University of Alabama at Birmingham

More American Men with Early-Stage Prostate Cancer Could Opt Out of Immediate Treatment

A new report on Swedish men with non-aggressive prostate cancer suggests that a lot more American men could safely choose to monitor their disease instead of seeking immediate radiation treatment or surgery. ...

– NYU Langone Medical Center

Embargo expired on 20-Oct-2016 at 11:00 ET

First Glimpse of End-of Chromosome Repair in Real Time

Researchers have developed a first-of-its- kind system to observe repair to broken DNA in newly synthesized telomeres, an effort that has implications for designing new cancer drugs. ...

– Perelman School of Medicine at the University of Pennsylvania

New Research Verifies TASINs as Viable Target for Colon Cancer Therapies

A small molecule called TASIN-1 can selectively kill cells with a mutation that is considered to be a precursor to colon cancer, while sparing related normal cells, UT Southwestern Medical Center cancer biologists have demonstrated. ...

– UT Southwestern Medical Center

Science Translational Medicine

Scientists Build a Better Cancer Drug to Pass Through Blood-Brain Barrier

In efforts to develop new treatments for brain cancer, scientists from Johns Hopkins Drug Discovery and the Kimmel Cancer Center's Bloomberg~Kimmel Institute for Cancer Immunotherapy report they have altered the structure of an experimental drug that...

– Johns Hopkins Medicine

Cancer Moonshot Official Simon to Address AACI/CCAF Annual Meeting

Cancer Moonshot Task Force Executive Director Greg Simon will speak at the 2016 AACI/CCAF Annual Meeting on Tuesday, October 25, in Chicago....

– Association of American Cancer Institutes (AACI)

Roots of Resistance to Cancer Drugs Run Deeper Than a Single Gene

Searching for more individual genes to predict responses to breast cancer therapy may not work, a new study suggests. Instead, scientists and clinicians need to pay attention to abnormalities in networks of genes, Yale researchers report in a paper p...

– Yale Cancer Center

Multiple Myeloma Studied in New Mouse Model Developed at Yale

Understanding how multiple myeloma develops and responds to therapies may be easier using a new mouse model developed at Yale University School of Medicine. The model supports the growth of cells derived from patients with multiple myeloma or the dis...

– Yale Cancer Center

Chemical Inhibitor May Provide Lung Cancer Treatment

Researchers at the Yale School of Medicine have identified a chemical inhibitor that limits the growth of lung tumor cells. The inhibitor works by partially disrupting glycosylation, the addition of sugar chains to proteins....

– Yale Cancer Center

Insight on Ovarian Cancer

In a recent study, senior author and Yale pathology professor Wang Min demonstrated that the tumors release substances called cytokines to attract macrophages. ...

– Yale Cancer Center

Journal of Clinical Investigation

New Study Highlights the Benefits of BRCA Testing for All People of Ashkenazi Jewish Descent

A new study published in the journal Genetics in Medicine, conducted by Montefiore-Einstein’s Program for Jewish Genetic Health (PJGH) and the Division of Reproductive and Medical Genetics, has found that BRCA screening should be routinely offered ...

– Montefiore Health System

Madison Startup Advances Three-in-One Cancer Drug Rooted at UW

Co-D Therapeutics, a University of Wisconsin-Madison spinoff, is developing a three-drug cocktail to battle a wide range of cancers. The first target for Co-D is angiosarcoma, a rare and lethal cancer that arises from blood vessels. ...

– University of Wisconsin-Madison

One-Third of Women Treated for Breast Cancer Are Not Getting Appropriate Breast Imaging Follow-Up Exam, New Study Finds

An annual mammogram is recommended after treatment for breast cancer, but nearly one-third of women diagnosed with breast cancer aren’t receiving this follow-up exam, according to new findings presented at the 2016 Annual Clinical Congress of the A...

– American College of Surgeons (ACS)

CE-1304-6543; UL1 TR000135; KL2TR000136-09 ; U10CA031946; U10CA033601; U10CA180821; U10CA180882; U10CA076001; U10CA025224

Embargo expired on 19-Oct-2016 at 17:45 ET

The Unseen Cancer Crisis: Alarming Disparities Found Across Appalachia

Rural Appalachia has gone from having the lowest cancer death rate in the country to the highest – and that’s just part of a growing cancer crisis in the region, new research from the School of Medicine suggests. Rural Appalachia has seen disturb...

– University of Virginia Health System

Do Risk Factors for Breast Cancer Change with a Woman’s Age?

Breast cancer is the most common cancer among women in the United States, with more than 230,000 diagnoses each year. Around 12.4 percent of American women will develop the disease at some point. Given these statistics, understanding and treating the...

– Texas A&M University

Cancer’s Big Data Problem

The Department of Energy is partnering with the National Cancer Institute in an “all-government” approach to fighting cancer. Part of this partnership is a three-year pilot project called the Joint Design of Advanced Computing Solutions for Cance...

– Argonne National Laboratory

Andrea Cheville, M.D. Of Mayo Clinic Elected to the National Academy of Medicine

Andrea Cheville, M.D., physical medicine and rehabilitation researcher and director of the Cancer Rehabilitation Program at Mayo Clinic, has been elected to the National Academy of Medicine....

– Mayo Clinic


$596K Grant Supports Examination of Chronic Stress in Breast Cancer Development

A Rutgers Cancer Institute of New Jersey researcher has received a $596,250 award (W81XWH-16-1-0358) from the U.S. Department of Defense to study the role of chronic stress in breast cancer development. The focus of the work is to explore how chroni...

– Rutgers Cancer Institute of New Jersey


Moffitt Cancer Center Hires World-Renowned Researcher as Co-Leader of the Immunology Program

José R. Conejo-Garcia, M.D., Ph.D. has joined Moffitt Cancer Center as co-leader of the Immunology Program and chair of the Department of Immunology. ...

– Moffitt Cancer Center

Tonya Edwards Receives MD Anderson’s Highest Nursing Honor

Tonya Edwards, a clinical nurse in Palliative Care at The University of Texas MD Anderson Cancer Center, is the recipient of the 2016 Brown Foundation Award for Excellence in Oncology Nursing....

– University of Texas M. D. Anderson Cancer Center

UofL Faculty Member Will Lead World’s Largest Oncology Social Work Group

Tara Schapmire is elected to roles with the Association of Oncology Social Work....

– University of Louisville

Physician-Scientist Dr. Bruce Clurman Named Executive Vice President and Deputy Director of Fred Hutch

Fred Hutchinson Cancer Research Center today announced the appointment of Dr. Bruce Clurman to serve as its executive vice president and deputy director, effective Nov. 1....

– Fred Hutchinson Cancer Research Center

Children’s Hospital Los Angeles Awarded Grant to Study Immunotherapy Resistance in Neuroblastoma

A team of investigators at Children’s Hospital Los Angeles has received a major, three-year grant from the V Foundation for Cancer Research to study the effects of chemoimmunotherapy in children with neuroblastoma. ...

– Children's Hospital Los Angeles Saban Research Institute

Researchers at Albert Einstein College of Medicine Receive $2.6 Million NIH Grant to Develop Targeted Cancer Immunotherapies

Researchers, led by Steven Almo, Ph.D., and Chandan Guha, M.B.B.S., Ph.D., at Albert Einstein College of Medicine have received a five-year, $2.6 million NIH grant to make immunotherapy agents that are more precise and effective at treating various t...

– Albert Einstein College of Medicine


Expert Pitch

UCLA's Dr. Michael Ong Can Comment on How Laws, Cigarette Taxes Can Curb Cancer Deaths

– University of California, Los Angeles (UCLA), Health Sciences

Sarcoma Expert at NewYork-Presbyterian Is Available to Discuss FDA Accelerated Approval of Olaratumab

– New York-Presbyterian Hospital

Yale Expert: Biomarker Testing in Lung Cancer

– Yale Cancer Center

Yale Expert: Counseling Patients at High-Risk for Breast Cancer on Preventive Mastectomy

– Yale Cancer Center

To Treat Breast Cancer, Give It a Lifeline

– Sanford Burnham Prebys Medical Discovery Institute





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