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Newswise Special Wire
Tuesday, December 20, 2016

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Newswise Cancer Research Wire for 20-Dec-2016

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Sunlight Offers Surprise Benefit — It Energizes Infection Fighting T Cells

Researchers have found that sunlight, through a mechanism separate than vitamin D production, energizes T cells that play a central role in human immunity. The findings suggest how the skin, the body’s largest organ, stays alert to the many microbe...

– Georgetown University Medical Center

Scientific Reports, Dec-2016

Embargo expired on 20-Dec-2016 at 05:00 ET

Cancer Registries in Resource-Constrained Countries Can Inform Policy to Reduce Cancer Burden

Data from population-based cancer registries are vital for informing health programs, policies and strategies for cancer screening and treatment. A special issue of Cancer Epidemiology, prepared under the auspices of the Centers for Disease Control a...

– RTI International

Cancer Epidemiology, Dec. 2016

Newly Identified Pathway in Mitochondria Fuels Tumor Progression Across Cancer Types

Wistar Scientists identified a novel protein pathway across several types of cancer that controls how tumor cells acquire the energy necessary for movement, invasion and metastasis. ...

– Wistar Institute

P01 CA140043; R01 CA78810; CA190027; R01 CA089720; R01 NS076709; F32 CA177018; T32 CA009171

Embargo expired on 19-Dec-2016 at 05:00 ET

How to Keep Nanoparticle "Caterpillars" Safe From The "Crows" of the Immune System

A University of Colorado Cancer Center paper published today in the journal Nature Nanotechnology details how the immune system recognizes nanoparticles, potentially paving the way to counteract or avoid this detection....

– University of Colorado Cancer Center

Nature Nanotechnology

Embargo expired on 19-Dec-2016 at 11:00 ET

Huntsman Cancer Institute Leads International Colorectal Study

Huntsman Cancer Institute (HCI) at the University of Utah will head an international study to find out how lifestyle and other health factors impact colon and rectal cancer outcomes. HCI was awarded an $8.8 million grant from the National Institutes ...

– Huntsman Cancer Institute at the University of Utah

U01CA206110; P30CA042014

Embargo expired on 19-Dec-2016 at 08:00 ET

Cancer Costs Leaving Patients in Debt

Research to be presented at the ESMO Asia 2016 Congress...

– European Society for Medical Oncology (ESMO)

ESMO Asia 2016 Congress

Moffitt Researchers Develop First Genomics-Driven Model for Personalized Radiation Therapy

Moffitt Cancer Center researchers have their study published today in The Lancet Oncology describing a novel genomics model that allows a personalized approach to radiation therapy....

– Moffitt Cancer Center

First Use of Graphene to Detect Cancer Cells

By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for ear...

– University of Illinois at Chicago

ACS Applied Materials & Interfaces, Nov-2016

Colorectal Cancer Prevention: A Proven Benefit of Nonsteroidal Anti-Inflammatory Drugs

Mayo Clinic researchers and a team of collaborating scientists from across the country have determined the comparative effectiveness of nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin and several supplements in preventing the recurrence of adv...

– Mayo Clinic


Breast Cancer Screening Disparities Exist for U.S. Minorities

Significant differences exist in breast cancer screening rates for racial groups in the United States — potentially negatively impacting the health of black and Hispanic women, notes a Journal of the American College of Radiology (JACR) study....

– American College of Radiology (ACR)

Embargo expired on 16-Dec-2016 at 09:00 ET

The 'Angelina Jolie' Effect, Chinese Herbal Treatment Shows Signs of Effectiveness in Bone Marrow Recovery, Nanoparticles Could Be Used to Overcome Treatment-Resistant Breast Cancer, and More in the Cancer News Source

Click here to go directly to the Cancer News Source...

– Newswise

AMP Issues New Joint Guidelines to Standardize Interpretation and Reporting of Sequence Variants in Cancer

AMP has published guideline recommendations for both clinical laboratory professionals and oncologists that assess the status of next-generation sequencing (NGS)-based cancer tests and establish standardized classification, annotation, interpretation...

– Association for Molecular Pathology

New Bioinformatics Tool Tests Methods for Finding Mutant Genes That ‘Drive’ Cancer

Computational scientists and cancer experts have devised bioinformatics software to evaluate how well current strategies distinguish cancer-promoting mutations from benign mutations in cancer cells....

– Johns Hopkins University

Proceedings of the National Academies of Science, Dec-13--2016; CA200266; CA180956-03; CA204817-01 ; CA62924

Early Surgery Increases Risk of Death for Some Uterine Cancer Patients, Penn Study Finds

Delaying surgery after a diagnosis of uterine cancer can increase a women’s risk of death, but operating too soon can be just as detrimental for some, Penn Medicine physicians report in a new study published in the American Journal of Obstetrics an...

– Perelman School of Medicine at the University of Pennsylvania

Journal of Obstetrics & Gynecology

New Trial Hopes to Increase Survival for Kids With Cancer, Reduce Risk of Long Term Cardiac Damage

Imagine conquering childhood cancer, only to find out that years down the road your heart may fail. Unfortunately, many children who have battled cancer face this reality. While often lifesaving, the effects of chemotherapy treatment (drugs that kill...

– Seattle Children's Hospital

Gastric Cancer Fueled by ‘Crosstalk’ Between Nerves and Cancer Cells

Gastric tumors are started by specialized cells in the stomach that signal nerves to make more acetylcholine, according to a study in mice. But blocking nerve growth factor inhibits the formation of stomach tumors. ...

– Columbia University Medical Center

Cancer Cell

Embargo expired on 15-Dec-2016 at 12:00 ET

Patient Prostate Tissue Used to Create Unique Model of Prostate Cancer Biology

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses. The achievement, say res...

– Georgetown Lombardi Comprehensive Cancer Center

Oncotarget, Dec-2016

New Gene Fusions and Mutations Linked to Gastrointestinal Stromal Tumors

In recent years, researchers have identified specific gene mutations linked to gastrointestinal stromal tumors (GIST), which primarily occur in the stomach or small intestine, but 10 to 15 percent of adult GIST cases and most pediatric cases lack the...

– University of California San Diego Health Sciences

Journal of Translational Medicine

Predicting Throat Cancer Recurrence with a Blood Test

Researchers found that patients whose oropharyngeal cancer recurred had higher levels of antibodies for two proteins, E6 and E7, which are found in HPV-fueled cancers. The finding suggests a potential blood-based marker that could predict when cancer...

– University of Michigan Health System

Clinical Cancer Research; CA97248; DC005356

The ‘Angelina Jolie’ Effect

Pop culture icons can influence our fashion choices, dietary habits and brand preferences, but can celebrities also influence our medical decisions?...

– Harvard Medical School


Embargo expired on 14-Dec-2016 at 18:30 ET

New Study Shows That Lung-Sparing Surgery for Patients with Advanced Mesothelioma Results in Prolonged Survival

Patients with advanced malignant pleural mesothelioma (MPM) treated with a combination of surgery to remove the cancer but save their lung, plus photodynamic therapy and chemotherapy, had a median survival of nearly three years, with a subset of pati...

– University of Maryland Medical Center/School of Medicine

Aspirin Slows Growth of Colon, Pancreatic Tumor Cells

Researchers have found that aspirin may slow the spread of some types of colon and pancreatic cancer cells. The study looks at the interaction between aspirin and blood platelets in cancer cells. ...

– American Physiological Society (APS)

Researchers Turn Back the Clock on Human Embryonic Stem Cells

Johns Hopkins scientists report success in using a cocktail of cell-signaling chemicals to further wind back the biological clock of human embryonic stem cells (ESCs), giving the cells the same flexibility researchers have prized in mice ESCs. ...

– Johns Hopkins Medicine

Development; U01HL099775, PCBC2012, R01EY023962, EY01765, R01HD082098, CA60441, CA006973, 2011-MSCRF-II-0008-00, 2007-MSCRF-II-0379-00, 2014-

Study Shows Nanoparticles Could Be Used to Overcome Treatment-Resistant Breast Cancer

Researchers at the University of Cincinnati (UC) College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in thes...

– University of Cincinnati (UC) Academic Health Center

American Chemical Society’s ACS Nano

Partners Play Critical Role in Melanoma Exams

A new Northwestern Medicine study shows the benefits of a partner frequently checking for troublesome moles based on training to do so far outweigh the embarrassment. Study participants who received skin examination training caught far more mole irre...

– Northwestern University

R01 CA154908

Scientist Discovers New Cancer Connection

A biologist at The University of Texas at Dallas and his colleagues have discovered that two enzymes previously linked independently with keeping cancer cells alive actually work in tandem to spur tumor growth. ...

– University of Texas at Dallas

Nature Communications, Dec. 14, 2016

Chinese Herbal Treatment Shows Signs of Effectiveness in Bone Marrow Recovery UCLA Research Alert

Researchers have found that a Chinese herbal regimen called TSY-1 (Tianshengyuan-1) TSY-1 increased Telomerase activity in normal blood cells but decreased it in cancer cells. Telomerase is an enzyme responsible for the production of telomeres, which...

– University of California, Los Angeles (UCLA), Health Sciences

Study Identifies Subtype of Triple Negative Breast Cancer That Responds Better to Chemotherapy

Researchers at Yale Cancer Center have identified a new subtype of triple negative breast cancer that shows significantly improved response to chemotherapy....

– Yale Cancer Center

PLOS Medicine

Unexpected Activity of Two Enzymes Helps Explain Why Liver Cancer Drugs Fail

Researchers at University of California San Diego School of Medicine have discovered that lack of two types of enzymes can lead to liver disease and cancer in mice. In human liver tumors, they found that deficiencies in these two enzymes, Shp2 and Pt...

– University of California San Diego Health Sciences

Cell Reports

Studies Probe Value and Impact of Direct-to-Consumer Genetic Testing

A series of scientific reports from the Personal Genomics study reveal insights into patient perceptions and experiences with direct-to-consumer genetic testing...

– Brigham and Women’s Hospital

Journal of Clinical Oncology

Agent of Mischief

Rhabdoid tumors are among the most recalcitrant childhood cancers, and scientists have long sought ways to understand what drives their resilience and makes them impervious to treatment. Now researchers from Harvard Medical School, St. Jude Children...

– Harvard Medical School

Policy and Public Affairs

AACI Thanks President Obama for Signing the 21st Century Cures Legislation

The Association of American Cancer Institutes (AACI) thanks President Barack Obama for signing the 21st Century Cures Act into law today. The legislation includes a NIH Innovation Account, which provides nearly $4.8 billion in funding for the Nationa...

– Association of American Cancer Institutes (AACI)


Pinnaclehealth Breast Care Center Re-Accredited by National Accreditation Program for Breast Centers (NAPBC)

The PinnacleHealth Breast Care Center has received three-year re-accreditation by the National Accreditation Program for Breast Centers (NAPBC), a program administered by the American College of Surgeons. The NAPBC represents a consortium of national...

– PinnacleHealth

Penn Immunotherapy Pioneer Elected to National Academy of Inventors

Yvonne J. Paterson, PhD, a professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, has been elected a fellow of the National Academy of Inventors. Fellows are named inventors on U.S. patents. Election to fellow...

– Perelman School of Medicine at the University of Pennsylvania

Penn Center for Precision Medicine Awards $525,000 in First Accelerator Grants

The Penn Center for Precision Medicine (PCPM) Accelerator Fund awarded eight research teams from Penn Medicine in their inaugural support of the implementation of personalized medicine projects across a gamut of clinical specialties. The projects cov...

– Perelman School of Medicine at the University of Pennsylvania

EMMC Cancer Care joins Dana-Farber Cancer Care Collaborative

EMMC Cancer Care, located at the Lafayette Family Cancer Center (Brewer, Maine), is the newest member of the Dana-Farber Cancer Care Collaborative. Participation in the Collaborative reflects a demonstrated commitment to excellence by meeting a wide ...

– Dana-Farber Cancer Institute

Memorial Sloan Kettering and Hackensack Meridian Health Announce Cancer Care Partnership

Memorial Sloan Kettering Cancer Center and Hackensack Meridian Health announced the Memorial Sloan Kettering–Hackensack Meridian Health partnership, a joint venture that will combine both organizations’ unparalleled expertise in all areas of canc...

– Memorial Sloan Kettering Cancer Center

Embargo expired on 14-Dec-2016 at 10:00 ET

Northwestern Medicine Chicago Proton Center To Offer P-Cure Upright Diagnostic Quality Imaging Technology

The Northwestern Medicine Chicago Proton Center will be the first proton center in the U.S. to use P-Cure’s innovative upright imaging technology for patients being treated for lung cancer. ...

– Northwestern Medicine

Indianapolis Entrepreneur Gives $30 Million for IU School of Medicine Immunotherapy Center

One of the largest gifts ever to the Indiana University School of Medicine will enable researchers to harness the power of the immune system to cure cancer and other devastating diseases -- propelling Indiana’s standing as an engine for biomedical ...

– Indiana University

UofL Study Examines Experiences of Muslim Cancer Survivors

A study being conducted at the University of Louisville School of Nursing will provide insight into cultural and religious influences on the experiences of Muslim cancer survivors living in the United States. The results will be used to develop cult...

– University of Louisville

Expert Pitch

Yale Expert on the Use of Immunotherapy After Chemoradiation in Head and Neck Cancer

– Yale Cancer Center





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