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Newswise Special Wire
Tuesday, January 17, 2017

Public edition |

Newswise Cancer Research Wire for 17-Jan-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Common Heart Drug Repurposed to Treat Rare Cancer in Europe

A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. The medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission (EC).

– Texas Tech University Health Sciences Center El Paso

Embargo expired on 17-Jan-2017 at 02:00 ET

Potentially Reversible Changes in Gene Control 'Prime' Pancreatic Cancer Cells to Spread

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it op...

– Johns Hopkins Medicine

Nature Genetics; CA54358, CA140599, CA179991, CA180682

Embargo expired on 16-Jan-2017 at 11:00 ET

Ludwig Study Reveals Why Cancer Cells Spread Within the Body

Findings uncover an ancient mechanism that makes cancer cells invasive, explains melanoma’s resistance to therapy and opens the door to development of novel cancer therapies

– Ludwig Cancer Research

Genes & Development

Best Treatment Option Written in Cancer's Genetic Script

Acute myeloid leukaemia study finds personalised therapy is possible.

– Wellcome Trust Sanger Institute

Nature Genetics

Lonely Hearts and Your Health - UCLA Health Advisory

Studies show that people who are chronically lonely have significantly more heart disease, are more prone to advanced cancers and strokes, and are more likely to develop neurodegenerative diseases such as Alzheimer’s.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences

Seeing Vape Pen in Use Boosts Desire to Smoke Among Young Adults

The newer e-cigarette vape pens (AKA vaporizers) may not look like cigarettes, but they stimulate the urge to smoke as powerfully as watching someone smoke a traditional tobacco cigarette.

– University of Chicago Medical Center

Nicotine & Tobacco Research

Embargo expired on 12-Jan-2017 at 12:00 ET

New Drug in Development Shows Improved Progression-Free Survival for Patients with Advanced Metastatic Midgut Neuroendocrine Tumors

A new therapy in development for the treatment of midgut neuroendocrine tumors, a rare type of cancer that occurs in the small intestine and colon, shows improved progression-free survival and response rates for patients with advanced disease. Result...

– Moffitt Cancer Center

New England Journal of Medicine, Jan 12-2017

NCI-Designated Cancer Centers Endorse Updated HPV Vaccination Recommendations

Recognizing a critical need to improve national vaccination rates for the human papillomavirus (HPV), Yale Cancer Center has again united with each of the 69 National Cancer Institute (NCI)-designated cancer centers in issuing a joint statement in su...

– Yale Cancer Center

“Mysterious” Non-Protein-Coding RNAs Play Important Roles in Gene Expression

Enhancers boost the rate of gene expression from nearby protein-coding genes so a cell can pump out more of a needed protein molecule. A mysterious subset of non-coding RNAs - enhancer RNAs (eRNAs) are transcribed from enhancer sequences. Shedding n...

– Perelman School of Medicine at the University of Pennsylvania

R01 501 CA078831, DP2MH107055

Cervical Cancer: A Preventable Disease

As the nation's 69 National Cancer Institute-designated cancer centers come together in support of recently updated HPV vaccination recommendations, a Rutgers Cancer Institute of New Jersey gynecologic oncologist shares insight on how this vaccine ca...

– Rutgers Cancer Institute of New Jersey

Embargo expired on 11-Jan-2017 at 00:05 ET

For Second Consecutive Year, NYU Langone Endorses National Initiative Advocating for Increased HPV Vaccination

Perlmutter Cancer Center at NYU Langone Medical Center is again joining with each of the 69 National Cancer Institute (NCI)-designated cancer centers in issuing a joint statement to increase vaccination against the human papillomavirus (HPV).

– NYU Langone Medical Center

Embargo expired on 11-Jan-2017 at 08:00 ET

Study: For Men with Prostate Cancer, Emotional Distress May Lead to More Aggressive Treatment

The anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers from the University at Buffalo and Roswell Park Cancer Institute report in a new study.

– University at Buffalo

Journal of Urology, Feb-2017

Simmons Cancer Center Joins National Cancer Institute, CDC Calling for Increased HPV Vaccinations to Prevent Cancer

More than a decade after the HPV vaccine was deemed both safe and effective by the FDA for preventing several types of cancer, the vaccine is still underused by those who could benefit.

– UT Southwestern Medical Center

Moffitt Cancer Center Researchers Develop Novel Treatment to Prevent Graft-Versus-Host-Disease

TAMPA, Fla. – Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants.  In a new study published as the cover story in Science Translational Medicine, Moffitt Cancer Cent...

– Moffitt Cancer Center

K08 HL11654701A1

UVA, Other NCI-Designated Cancer Centers Endorse Latest HPV Vaccination Recommendations

Together with the other 68 National Cancer Institute-designated cancer centers, University of Virginia Cancer Center supports the latest human papillomavirus (HPV) vaccination recommendations to help prevent HPV-related cancers. The U.S. Centers for ...

– University of Virginia Health System

Walking the Tightrope

Antibiotic use represents a special challenge, in which too much of a good thing can be dangerous to public health as a whole. The fight against a common, costly, hospital-acquired infection known as Clostridium difficile, or C. diff offers an illumi...

– Perelman School of Medicine at the University of Pennsylvania

Mayo Clinic Cancer Center Joins 69 National Cancer Institute-Designated Cancer Centers to Endorse Updated HPV Vaccine Recommendations

Mayo Clinic Cancer Center today joined with 69 National Cancer Institute-designated cancer centers in issuing a joint statement supporting updated HPV vaccination guidelines from the Centers for Disease Control and Prevention (CDC).

– Mayo Clinic

New Study Shows Promise for Repurposing Anti-Malarial Drug for Cancer Treatment

A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine – a drug currently used to treat malaria – may be useful in treating patients with metastatic cancers.

– University of Kentucky

Cell Reports

Unique Gene Signature Predicts Potentially Lethal Prostate Cancers

Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones. However, for some men, prostate cancer recurs despite androgen-deprivation therapy. A team ...

– Roswell Park Cancer Institute

Researchers Develop New Compound to Fight Cytomegalovirus

A Retro94-based compound may prevent a common and sometimes fatal virus, human cytomegalovirus (CMV) from reproducing and protect immunocompromised patients, like those with HIV, on chemotherapy, with transplants and infants from the effects of the d...

– Penn State Health Milton S. Hershey Medical Center

Journal of Virology

Tucatinib (ONT-380) Progressing in Pivotal Trial Against HER2+ Breast Cancer

Twenty-seven percent of 50 heavily pretreated patients with stage IV breast cancer saw clinical benefit from the drug, with at least “stable disease” at 24 or more weeks after the start of treatment.

– University of Colorado Cancer Center

Clinical Cancer Research


Young Scientists Get Boost in Funding From Johns Hopkins and Bladder Cancer Advocacy Network

Young scientists interested in bladder cancer research can compete for up to two awards totaling $100,000 from a joint effort between the Johns Hopkins Greenberg Bladder Cancer Institute and the Bladder Cancer Advocacy Network (BCAN).

– Johns Hopkins Medicine

HOPA Applauds Reintroduction of Pharmacy and Medically Underserved Areas Enhancement Act

The Hematology/Oncology Pharmacy Association (HOPA) applauds Senators Chuck Grassley (R-IA), Susan Collins (R-ME), Sherrod Brown (D-OH), and Bob Casey (D-PA) for introducing S. 109, the Pharmacy and Medically Underserved Areas Enhancement Act.

– Hematology Oncology Pharmacy Association

Columbia, NewYork-Presbyterian and Non-Profit Life Raft Group Form Cancer Research Partnership

Collaboration will investigate the efficacy of a system biology approach to identifying treatment options for patients with advanced gastrointestinal stromal tumors.

– Columbia University Medical Center

Embargo expired on 12-Jan-2017 at 10:00 ET

MD Anderson and Deerfield Management Create Vescor LLC to Develop Novel Therapeutics Based on Inhibiting Autophagy for Treatment of Specific Cancers

Vescor LLC, a new company focused on discovery and development of autophagy targeted therapeutics for cancer treatment, has been formed by The University of Texas MD Anderson Cancer Center, Deerfield Management and two leading autophagy experts.

– University of Texas M. D. Anderson Cancer Center

MD Anderson and Nation’s Cancer Centers Jointly Endorse Updated HPV Vaccine Recommendations

As national vaccination rates for the human papillomavirus (HPV) remain low, The University of Texas MD Anderson Cancer Center has again united with the 68 other National Cancer Institute (NCI)-designated cancer centers in issuing a joint statement e...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 11-Jan-2017 at 00:05 ET

The Princess Margaret Successfully Achieves Historic Billion Dollar Challenge for Personalized Cancer Medicine

The Princess Margaret Cancer Foundation is thrilled to announce the successful achievement of our Billion Dollar Challenge, in partnership with the Princess Margaret Cancer Centre at University Health Network.

– University Health Network (UHN)

Embargo expired on 11-Jan-2017 at 09:00 ET

Medical Imaging Innovator Christine Hendon Wins Presidential Honor

Christine Hendon, assistant professor of electrical engineering at Columbia Engineering, has won the Presidential Early Career Award (PECASE), the highest honor the U.S. government gives to young scientists and engineers. Hendon, who develops innovat...

– Columbia University School of Engineering and Applied Science

Physicians at Rush Named ‘Top Cancer Doctors’ by Chicago Magazine

Twenty-three physicians from Rush University Medical Center were named 'top cancer doctors' in the January 2017 issue of Chicago magazine.

– Rush University Medical Center

Expert Pitch

Ben Stiller's Surgeon Edward Schaeffer, MD Is Available to Discuss New Prostate Cancer PSA Testing Study

– Northwestern Medicine

Innovative Breast Reconstruction: An Amazing Result Enhances Self-Esteem

– Yale Cancer Center

Gynecologic Cancers Expert at Newyork-Presbyterian Is Available to Discuss HPV Vaccination and Cancer Prevention

– New York-Presbyterian Hospital





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