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Newswise Special Wire
Wednesday, January 25, 2017

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Newswise Cancer Research Wire for 25-Jan-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Large Pre-ACA Medicaid Expansion Did Not Level Health Disparities in Cancer Surgery

An analysis of the New York State’s Medicaid expansion, which predated the 2010 Affordable Care Act, finds substantial decrease in uninsured rate but little change in racial disparities when it comes to access to cancer surgery – a proxy for comp...

– Georgetown University Medical Center

Embargo expired on 24-Jan-2017 at 10:00 ET

Lung Cancer Screening Programs in Communities Are Vital, but Challenges Exist

Implementing lung cancer screening as a high-quality preventive health service in a community setting is feasible, but comes with several key challenges, according to a scientific presentation at the 53rd Annual Meeting of The Society of Thoracic Sur...

– The Society of Thoracic Surgeons

Embargo expired on 24-Jan-2017 at 10:00 ET

Half of Breast Cancer Patients Experience Severe Side Effects

Nearly half of women treated for early stage breast cancer reported at least one side effect from their treatment that was severe or very severe, a new study finds.

– Michigan Medicine - University of Michigan

Cancer; CA163233

Embargo expired on 24-Jan-2017 at 09:00 ET

Study Unveils New Way to Starve Tumors to Death

Scientists at Washington University School of Medicine in St. Louis have exploited a common weak point in cancer cell metabolism, forcing tumor cells to reveal the backup fuel supply routes they rely on when this weak point is compromised. Mapping th...

– Washington University in St. Louis

Cell Reports

Embargo expired on 24-Jan-2017 at 12:00 ET

Breast Density Research Edges Closer to Cancer Prevention

Australian researchers are one step closer to breast cancer prevention after finding a new driver for breast density, an identified risk factor for breast cancer.

– University of Adelaide

Breast Cancer Research

Can Prostate Cancer Metastasis Be Stopped Before It Starts? Research Team Identifies Role for Particular MicroRNA

Metastasis, or spread of a tumor from the site of origin to additional organs, causes the vast majority of cancer-related deaths, but our understanding of the molecular mechanisms behind metastasis remains limited. A research team led by Dean Tang, P...

– Roswell Park Cancer Institute

Penn Researchers Help Unravel Mysteries of Pancreatic Cancer’s Resistance to Standard Therapies

In a new study, researchers at the Perelman School of Medicine at the University of Pennsylvania have illuminated one of pancreatic cancer’s major resistance mechanisms: a form of inflammation that is triggered by the tumor in response to treatment...

– Perelman School of Medicine at the University of Pennsylvania

K08 CA138907; F30 CA196106; F30 CA196124

KU Researchers Find Statins May Hold Keys to Future Cancer Treatment

Researchers at The University of Kansas Cancer Center have found that high doses of drugs commonly used to fight high cholesterol can destroy a rogue protein produced by a damaged gene that is associated with nearly half of all human cancers

– University of Kansas Cancer Center

Nat Cell Bio, Nov-2016

Timing of Chemo Affects Inflammation, Mice Study Suggests

COLUMBUS, Ohio – The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests.

– Ohio State University

Scientific Reports

ASTRO Supports Nomination of Dr. David Shulkin to Lead Department of Veterans Affairs

The American Society for Radiation Oncology (ASTRO) today expressed strong support for the nomination of David Shulkin, MD, as Secretary of the Department of Veterans Affairs (VA).

– American Society for Radiation Oncology (ASTRO)

Cervical Cancer Death Rates Higher Among Older and Black Women

A woman’s risk of dying of cervical cancer is higher than long believed, particularly among older and black women, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

– Johns Hopkins Bloomberg School of Public Health


Embargo expired on 23-Jan-2017 at 00:05 ET

Research Helps Explain How B Cell Metabolism Is Controlled

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) addresses the lack of knowledge about how B cell metabolism adapts to each of their various environments-- development in the bone marrow, proliferation and hypermutation in t...

– Sanford Burnham Prebys Medical Discovery Institute

Nature Immunology; NIH R01AI41649 ; NIH 5P30CA030199

Embargo expired on 23-Jan-2017 at 11:00 ET

Scientists Get Best View Yet of Cancer-Causing Virus HPV

New details of the structure of the human papillomavirus (HPV) may lead to better vaccines and HPV anti-viral medications, according to research led by a Penn State College of Medicine researcher.

– Penn State College of Medicine

A Gene’s Journey From Covert to Celebrated

Unmasking a previously misunderstood gene, Gpr182, University of North Carolina scientists discover an unlikely potential drug target for gastrointestinal cancers.

– University of North Carolina Health Care System

Journal of Clinical Investigation

Tulane Researchers Find Tumor-Suppressing Protein Actually Promotes Cancer

Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers. The discovery could expl...

– Tulane University

Researchers Unlock Mechanism of Drug Resistance in Aggressive Breast Cancer

In the journal Cancer Discovery, UNC Lineberger Comprehensive Cancer Center researchers and colleagues report findings of how triple negative breast cancer cells are able to bypass treatment with trametinib, a U.S. Food and Drug Administration-approv...

– University of North Carolina Health Care System

Cancer Discovery

Molecular Subgroups of Non-Small Cell Lung Cancer Predict Tumor Behavior, Reveal Treatment Targets

EGFR mutations is associated with a longer median overall survival (almost double) compared with those without EGFR mutations when treated with specific targeted agents.

– Sbarro Health Research Organization (SHRO)


Reproducibility Project: Cancer Biology Publishes First Five Replication Studies Conducted by Science Exchange

/PRNewswire/ -- Science Exchange, the leading marketplace for scientific research, is excited to announce that the first five replication studies from the Reproducibility Project: Cancer Biology (RP:CB) have been published in eLife today. Despite int...

– Science Exchange

Affordable Care Act Made Cancer Screening More Accessible for Millions, Study Finds

The Affordable Care Act helped make recommended cancer screening more affordable and accessible for millions of Americans, according to new University of Virginia research.

– University of Virginia Health System

As Cells Age, the Fat Content Within Them Shifts

As cells age and stop dividing, their fat content changes, along with the way they produce and break down fat and other molecules classified as lipids. By providing broad insights into the connection between lipids and cellular aging, the findings op...

– University at Buffalo

Molecular BioSystems

Breast Cancer Prognosis of African-American Patients May Improve with Administration of Chemotherapy Before Surgery, Study Finds

Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study.

– Georgia State University


Brain Tumor Survivor Moves Into Next Phase of Life Thanks to Rehab Experts

Physical therapist Jorge Neira is helping Ruben Arellano regain use of his arms and the ability to walk. Arellano had a baseball-sized tumor removed from his head. The two share successes and setbacks on the arduous road to recovery at Harris Health ...

– Harris Health System

Mayo Researchers Identify Mechanism of Oncogene Action in Lung Cancer

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. In a new paper published this week in Cancer Cell, Mayo Clinic researchers provide genetic evidence that Ect2 drives lung adenocarcinoma ...

– Mayo Clinic

Small Intestine GIST Associated with Better Prognosis in Younger Patients

Gastrointestinal stromal tumors (GIST) are tumors that arise is the wall of the digestive tract, and most often occur in the stomach or small intestine. Though more common in later in life, GISTs can occur in adolescents and young adults (AYA) under ...

– University of California San Diego Health Sciences

JAMA Surgery

Structure of Atypical Cancer Protein Paves Way for Drug Development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.

– Case Western Reserve University

Nature Communications, Jan-2017; U01 GM094612; U54 GM094618; R01 GM071872; R01 AI118985; R01 AI37113; R21 AI121918; R21 AI122211; GM117424 ...

Mayo Clinic Researchers Identify Cancer-Fighting Drugs That Help Morbidly Obese Mice to Lose Weight

Scientific investigations sometimes result in serendipitous discoveries which shift the investigations from one focus to another. In the case of researchers at Mayo Clinic in Arizona, studies addressing obesity’s impact on cancer treatment resulted...

– Mayo Clinic

Immune Responses Against a Virus-Related Skin Cancer Suggest Ways to Improve Immunotherapy

Researchers at Seattle’s Fred Hutchinson Cancer Research Center and the University of Washington say a new study suggests ways to improve immune therapy for certain cancers including a virus-associated form of Merkel cell carcinoma, a rare, aggress...

– Fred Hutchinson Cancer Research Center

Cancer Immunology Research, Jan. 16, 2017

Study Challenges Potential Pancreatic Cancer Target

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds. PDX1 is critical for cancer growth, but blocking it may lead to more aggressive tumors.

– Michigan Medicine - University of Michigan

Genes and Development; CA172045; CA112537; CA159222; CA046592

As Thyroid Cancer Rates Rise, Focus on Detection - UCLA Health Advisory

Thyroid cancer typically affects more women than men and can be difficult to diagnose.

Expert Available

– University of California, Los Angeles (UCLA), Health Sciences

Policy and Public Affairs

UC Davis and Nation's Cancer Centers Jointly Endorse Updated HPV Vaccine Recommendations

Recognizing a critical need to improve national vaccination rates for the human papillomavirus (HPV), UC Davis Comprehensive Cancer Center has again united with each of the 69 National Cancer Institute (NCI)-designated cancer centers in issuing a joi...

– UC Davis Comprehensive Cancer Center


CIRM Approves New Funding to UC San Diego Researchers Fighting Zika Virus and Cancer

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatmen...

– University of California San Diego Health Sciences

Dustin McGowan of the Miami Marlins selected as 52nd Hutch Award Winner

Fred Hutchinson Cancer Research Center announced Miami Marlins pitcher Dustin McGowan has been named the 52nd annual Hutch Award winner. The award is given yearly to a Major League Baseball player who best exemplifies the honor, courage and dedicatio...

– Fred Hutchinson Cancer Research Center

Northwestern to Lead Trial for Rare Cancer Patients

CHICAGO --- A novel national trial for people with no established alternative to treat their rare cancers is being co-led by Northwestern Medicine investigators, who helped conceive of and develop the project.The clinical trial called DART will offer...

– Northwestern University

January Is Thyroid Awareness Month

Mount Sinai Doctors Stress Importance of Self-Examinations for Early Detection

– Mount Sinai Health System

$1.8M Grant Aids Exploration of Chronic Stress Role in Cancer Development

A five-year, $1.8 million grant (R01CA203965) from the National Cancer Institute awarded to Rutgers Cancer Institute of New Jersey resident research member Wenwei Hu, PhD, will support research to further explore how chronic stress impacts cancer dev...

– Rutgers Cancer Institute of New Jersey






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