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Newswise Special Wire
Tuesday, February 7, 2017

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Newswise Cancer Research Wire for 07-Feb-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

UNM Cancer Center Researcher Discovers New Class of Drugs to Combat Aging Diseases

Eric Prossnitz, PhD and his team uncovered new details of the aging process. They discovered an altered balance between certain signaling molecules in the smooth muscle cells of blood vessels and the heart. The team also discovered a new class of dru...

– University of New Mexico Comprehensive Cancer Center

Science Signaling

16 Aplastic Anemia Patients Free Of Disease After Bone Marrow Transplant and Chemo

Physicians at the Johns Hopkins Kimmel Cancer Center report they have successfully treated 16 patients with a rare and lethal form of bone marrow failure called severe aplastic anemia using partially matched bone marrow transplants followed by two hi...

– Johns Hopkins Medicine

Biology of Blood and Marrow Transplantation; K23HL123601-01

Researchers Identify ‘Synthetic Essentiality’ as Novel Approach for Locating Cancer Therapy Targets

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes. The process, which located a genetic site for the most common form of prostate cancer, has potential for developing precision ther...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 06-Feb-2017 at 11:00 ET

New Technique Slashes Diagnosis Time During Brain Surgery

Neurosurgeons want the quickest, most accurate information to help them make decisions during brain tumor surgery. A new technique could help.

– Michigan Medicine - University of Michigan

Nature Biomedical Engineering, Feb-2017; R01EB017254; K08NS087118; R01EB010244-01; P30CA046592; 2UL1TR000433

Embargo expired on 06-Feb-2017 at 11:00 ET

Immune Therapy Scientists Discover Distinct Cells That Block Cancer-Fighting Immune Cells

Princess Margaret Cancer Centre scientists have discovered a distinct cell population in tumours that inhibits the body’s immune response to fight cancer.

– University Health Network (UHN)

Nature Medicine, Feb-2017

Embargo expired on 06-Feb-2017 at 11:00 ET

Scientists Catalogue “Parts List” of Brain Cell Types in a Major Appetite Center

Using Harvard-developed technology, scientists at Beth Israel Deaconess Medical Center (BIDMC) have catalogued more than 20,000 brain cells in one region of the mouse hypothalamus. The study, published in Nature Neuroscience, revealed some 50 distinc...

– Beth Israel Deaconess Medical Center

R01 DK096010; R01 DK089044; R01 DK071051; R01 DK075632; R37 DK053477; P30 DK046200; P30 DK057521; R01 DK102170; R01 DK085171; R01 DK102173...

Scientists Discover Why Some Cancers May Not Respond to Immunotherapy

UCLA scientists have discovered that people with cancers containing genetic mutations JAK1 or JAK2, which are known to prevent tumors from recognizing or receiving signals from T cells to stop growing, will have little or no benefit from the immunoth...

– University of California, Los Angeles (UCLA), Health Sciences

Removal of Ovaries During Hysterectomy Linked to Increase in Heart Disease, Cancer and Premature Death

A study led by the University of Warwick has found a link between the removal of ovaries during hysterectomy and an increase in heart disease, cancer and premature death.

– University of Warwick

BMJ 2017;356:j372

Yale Study: 1 in 4 Teen E-Cigarette Users Have Tried 'Dripping'

Yale researchers found in a study that one in four high schoolers who use electronic cigarettes are inhaling vapors produced by dripping e-liquids directly onto heating coils, instead of inhaling from the e-cigarette mouthpiece, possibly increasing e...

– Yale Cancer Center

Why Doctors May Keep a Patient Awake for Brain Surgery

A rare look at brain surgery with the patient alert and awake at Smilow Cancer Hospital at Yale-New Haven.

– Yale Cancer Center

Lieutenant Gov. Kathy Hochul Celebrates Launch of Innovative Immunotherapy Biotech Company Based in Buffalo

• New Roswell Park spinoff company will develop next-generation cancer immunotherapies • Novel approach combines unique adoptive T cell therapy with genetically engineered stem cell therapy • Clinical trial planned in ovarian, pancreatic, lun...

– Roswell Park Cancer Institute

Cancer Drug Could Double as a Weapon Against Heart Disease, Promoting Regeneration of Damaged Heart Tissue

An anticancer agent in development promotes regeneration of damaged heart muscle – an unexpected research finding that may help prevent congestive heart failure in the future.

– UT Southwestern Medical Center

New Treatment Guides from NCCN Help Patients with Waldenström’s Macroglobulinemia Make Informed Care Decisions

NCCN has published the NCCN Guidelines for Patients® and NCCN Quick Guide™ sheet for Waldenström’s Macroglobulinemia—a rare, but manageable type of Non-Hodgkin’s Lymphoma.

– National Comprehensive Cancer Network® (NCCN®)

Under and Misuse of Hormone Therapy Decreasing, but Still High

A nationwide cancer registry of almost one million patients treated for hormone-sensitive breast cancer shows that one out of six women who should have received post-surgical treatment known as adjuvant endocrine therapy did not get this recommended ...

– University of Chicago Medical Center

JAMA Oncology, Feb. 2, 2017

Embargo expired on 02-Feb-2017 at 11:00 ET

UAB Study Shows Children and Parents Over-Report Leukemia Medication Adherence

New research from UAB suggests that young patients with acute lymphocytic leukemia, or ALL — the most common type of pediatric cancer — and their parents are likely to report to their physician that they took more of their anti-cancer medication ...

– University of Alabama at Birmingham


The Best Treatment for Laryngeal Cancer? This Approach Helps Decide

After a decade of using a novel approach to select patients for laryngeal cancer treatment, researchers are reporting "exceptional" survival rates nearing 80 percent, even for the most advanced patients.

– Michigan Medicine - University of Michigan

JAMA Otolaryngology - Head and Neck Surgery; CA097248 ; CA046592

Yale Scientists Identify Key Defect in Brain Tumor Cells

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

– Yale Cancer Center

Blood Test That Detects Changes in Tumor DNA Predicts Survival of Women with Advanced Breast Cancer

Results of a multicenter study of 129 women with advanced breast cancer show that a blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those ...

– Johns Hopkins Medicine

Journal of Clinical Oncology; P30CA006973, P30CA58223

Potential New Drug Class Hits Multiple Cancer Cell Targets, Boosting Efficacy and Safety

In a new paper published this week in <i>PNAS</i>, researchers at the University of California San Diego School of Medicine and Moores Cancer Center, in collaboration with colleagues at Rady Children’s Hospital-San Diego, the University of Colorado...

– University of California San Diego Health Sciences


New Radiotracer Could Make Diagnosing Prostate Cancer Faster and Easier

Researchers at NIBIB have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial. Prostate cancer is the fifth leading cause of death worldwide and is especially difficult to diagnose. While prostate...

– National Institute of Biomedical Imaging and Bioengineering

The Journal of Nuclear Medicine, Feb-2017

Neutrons Identify Critical Details in Bacterial Enzyme Implicated in Gastric Cancer

Neutron analysis at the Department of Energy’s Oak Ridge National Laboratory is helping researchers better understand a key enzyme found in a bacterium known to cause stomach cancer. Understanding the details of this enzyme, and thus the Helicob...

– Oak Ridge National Laboratory

Two New Trials for Pediatric Brain Cancer Open at UTHealth/Children’s Memorial Hermann

Two new clinical trials for pediatric brain cancer have begun at The University of Texas Health Science Center at Houston (UTHealth) and Children’s Memorial Hermann Hospital.

– University of Texas Health Science Center at Houston

Sanford Studying Immunotherapy Drug for Esophageal Cancer

A clinical trial at Sanford Health is studying if an immunotherapy drug developed by Merck might be able to treat certain patients with advanced esophageal cancer. The Merck Keynote 181 trial is now open at Sanford.

– Sanford Health

Policy and Public Affairs

ASTRO Urges Lawmakers to Maintain Health Care Access for Vulnerable Patients

As the new Congress and administration wrestle with policy decisions on the provision of high quality, affordable health coverage, the American Society for Radiation Oncology (ASTRO) urges policymakers to prioritize reforms that avoid disruption in c...

– American Society for Radiation Oncology (ASTRO)


Monell Center Receives Grant to Characterize Distinctive Odor of Ovarian Cancer

A new grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation will allow Monell scientists and collaborators to confirm initial findings of a unique odor pattern for ovarian cancer. The multi-disciplinary team will use the information t...

– Monell Chemical Senses Center

Fred Hutch’s Paulovich Laboratory to Lead Protein Assay Work for National Beau Biden Cancer Moonshot

Paulovich’s lab will develop a customized panel of MRM (multiple reaction monitoring)-based assays and deploy these assays to quantify tumor proteins in clinical samples from patients receiving treatment. Other collaborators in the Moonshot project...

– Fred Hutchinson Cancer Research Center

Prominent Surgeon and Researcher to Lead Multidisciplinary Liver Cancer Initiative

Theodore H. Welling, III, MD, will lead a new state-of-the-art liver cancer program at NYU Langone to advance clinical care and accelerate the translation of lab breakthroughs into superior treatments.

– NYU Langone Medical Center

MD Anderson to Present Making Cancer History® Seminar in Indian Wells

The University of Texas MD Anderson Cancer Center returns to Southern California this month with its Making Cancer History® Seminar, 3:30-5:30 p.m. Feb. 20 at the Renaissance Indian Wells Resort and Spa, 44400 Indian Wells Lane.

– University of Texas M. D. Anderson Cancer Center

MD Anderson Supports World Cancer Day with Allies Around the Globe

In honor of World Cancer Day on Feb. 4, The University of Texas MD Anderson Cancer Center calls for health care providers, organizations, governments and individuals to unite in the common goal of eliminating cancer. Driven to accelerate progress tow...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 04-Feb-2017 at 07:00 ET

Outstanding Investigator Award Honors U Chicago Cancer Researcher

University of Chicago cancer specialist Thomas Gajewski, MD, PhD, a pioneer in the field of cancer immunotherapy, has been awarded an Outstanding Investigator Award by the National Cancer Institute, a branch of the National Institutes of Health. The ...

– University of Chicago Medical Center

Expert Pitch

Gynecologic Cancers Expert at NewYork-Presbyterian Available to Discuss the Connection of Weight Loss and Endometrial Cancer Based on a New Study in the Journal of Clinical Oncology

– New York-Presbyterian Hospital

Embargo expired on 06-Feb-2017 at 16:05 ET

When to See a Doctor About Moles and Changes in Your Skin

– University Hospitals Cleveland Medical Center





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