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Newswise Special Wire
Tuesday, February 21, 2017

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Newswise Cancer Research Wire for 21-Feb-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Penn Expert Calls for Shorter Radiation Use in Prostate Cancer Treatment

Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to Justin Bekelman, MD, an associate professor of Radiation Oncology, Medical Ethics, and Health Policy at the University ...

– Perelman School of Medicine at the University of Pennsylvania


The Way Breast Cancer Genes Act Could Predict Your Treatment

A Michigan State University breast cancer researcher has shown that effective treatment options can be predicted based on the way certain breast cancer genes act or express themselves.

– Michigan State University


GW Cancer Leader Co-Authors Lancet Commentary on International Cancer Control Access & Equity

Mandi Pratt-Chapman, M.A., associate center director for patient-centered initiatives and health equity at the GW Cancer Center, co-authored a commentary published in The Lancet Oncology, which calls to bridge the gap between the achievable and the a...

– George Washington University

What Turns Benign Central Nervous System Tumors Deadly

In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40% chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors.

– Yale Cancer Center

Nature Communications

Biomarker Predicts Poor Prognosis in African-Americans with Triple-Negative Breast Cancer, Study Finds

Having high levels of a certain biomarker is linked to poor prognosis in African-American patients with triple-negative breast cancer, while the same biomarker doesn’t influence disease outcomes in white patients, according to a new study.

– Georgia State University

Scientific Reports

New Approach to Cervical Cancer Care in Botswana Cuts Lag Time Between Treatment and Diagnosis in Half

Cervical cancer is the leading cause of cancer deaths for women low- and middle-income countries, including Botswana, where 75 percent of cervical cancer patients suffer from advanced forms of the disease. These patients can face wait times as long a...

– Perelman School of Medicine at the University of Pennsylvania

Protein Once Thought Exclusive to Neurons Helps Aggressive Cancers Grow, Spread, and Defy Death

How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive ...

– UT Southwestern Medical Center

UNC Researcher Finds Safer, Less-Invasive Method of Staging Endometrial Cancer

A UNC-Chapel Hill researcher has published a study in Lancet Oncology online that identifies sentinel-lymph-node mapping as a safer and less-invasive method of staging endometrial cancer that is equally as accurate as the more traditional lymphadenec...

– University of North Carolina Health Care System

BRCA Gene Plus Breast Cancer History Leads to Preventive Strike Against Pancreatic Cancer

More than three decades after surviving breast cancer, Susanne Calabrette faced a second scare. In June 2016, an MRI for an unrelated condition revealed she had pancreatic cysts, giving her a chance for a pre-emptive strike against this killer cancer...

– UT Southwestern Medical Center

Researchers Are First to See DNA 'Blink'

Northwestern University biomedical engineers have developed imaging technology that is the first to see DNA “blink,” or fluoresce. The tool enables researchers to study individual biomolecules (DNA, chromatin, proteins) as well as important globa...

– Northwestern University

2017 AAAS annual meeting, Feb. 17, 2017

Embargo expired on 17-Feb-2017 at 13:00 ET

Micro-RNA May Amplify Effectiveness of Sorafenib in Difficult Liver Cancer Cases

Only 25% of patients respond to sorafenib treatment, so researchers have endeavored to understand its mechanism of action and discover a way to boost its effectiveness.

– Sbarro Health Research Organization (SHRO)

J Cell Physiol. 2016 Dec 16. doi: 10.1002/jcp.25744

Scientists Monitor Crosstalk Between Intestinal Microbes and Immune System

Harvard Medical School researchers have successfully “listened in” on the crosstalk between gut microbes and the immune system.

– Harvard Medical School


Doctors Treat Deadly Cancerous Disorders with Gene-Guided, Targeted Therapy

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them. Researchers ...

– Cincinnati Children's Hospital Medical Center

JCI Insight Feb. 9, 2017

Looking Beyond Cancer Cells to Understand What Makes Breast Cancer Spread

A new study from researchers at the University of Michigan Comprehensive Cancer Center identifies a protein in that microenvironment that promotes the spread of breast cancer cells. It’s part of a well-known family of receptors for which promising ...

– Michigan Medicine - University of Michigan

Cell Reports; CA125577; CA107469; CA19084; GM086262; CA046592

Specialized Cancer Centers Play a Role in Survival of Adolescents and Young Adults with Acute Leukemia

A UAB study shows specialized treatment sites contribute to better survival rates for those with acute leukemia.

– University of Alabama at Birmingham

Cancer Epidemiology, Biomarkers & Prevention, Feb. 2016

Targeted Radiosurgery Better Than Whole-Brain Radiation for Treating Brain Tumors

Tumors that originate in other organs of the body and spread to the brain are known as metastatic brain tumors. According to the American Brain Tumor Association, this type of tumor is the most common in adults, affecting as many as 300,000 people ea...

– University of Missouri Health


New Studies Unravel Mysteries of How PARP Enzymes Work

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

– UT Southwestern Medical Center

Molecular Cell, Jan-2017

Cancer Researchers to Convene for Multidisciplinary Thoracic Cancers Symposium in March

The 2017 Multidisciplinary Thoracic Cancers Symposium, co-sponsored by the American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO) and The Society of Thoracic Surgeons (STS), will feature advances in surgery,...

– American Society for Radiation Oncology (ASTRO)

Multidisciplinary Thoracic Cancers Symposium

Analyzing Copies of Genes Offers New Treatment Possibilities for Ovarian Cancer

A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has developed a new tool to analyze an often overlooked aspect of cancer genetics — an alteration that results in the loss or gain in a copy of ...

– University of California San Diego Health Sciences

Nature Communications

Embargo expired on 15-Feb-2017 at 05:00 ET

DNA Patterns Can Unlock How Glucose Metabolism Drives Cancer, Study Finds

Less aggressive cancers are known to have an intact genome—the complete set of genes in a cell—while the genome of more aggressive cancers tends to have a great deal of abnormalities. Now, a new multi-year study of DNA patterns in tumor cells sug...

– University of California, Los Angeles (UCLA), Health Sciences

Molecular Systems Biology

Embargo expired on 15-Feb-2017 at 12:00 ET

Scientists Discover How the Cells in Skin and Organ Linings Maintain Constant Cell Numbers

Research published today in Nature from scientists at Huntsman Cancer Institute (HCI) at the University of Utah shows how epithelial cells naturally turn over, maintaining constant numbers between cell division and cell death.

– University of Utah Health Sciences

Nature; 2OD002056; GM102169; CA042014

Embargo expired on 15-Feb-2017 at 13:00 ET

Payers Weigh the Implications of Multigene Testing Coverage in New UCSF Study

A recent study from the UCSF Center for Translational and Policy Research on Personalized Medicine and the UCSF Helen Diller Family Comprehensive Cancer Center identified opportunities to address the barriers to coverage of hereditary cancer panels, ...

– National Comprehensive Cancer Network® (NCCN®)

Study Points to Potential New Brain Cancer Treatment

A recent Yale study may have found a new way to fight brain cancer.

– Yale Cancer Center

Science Translational Medicine

Genome Analysis Helps Keep Deadly Brain Cancer at Bay for Five Years

An analysis of a patient’s deadly brain tumor helped doctors at Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report in the journal Genome Medicine.

– Yale Cancer Center

Genome Medicine

More Patients with Early-Stage Breast Cancer May Be Able to Avoid Chemotherapy in the Future

Women with early-stage breast cancer who had an intermediate risk recurrence score (RS) from a 21-gene expression assay had similar outcomes, regardless of whether they received chemotherapy, a new study from The University of Texas MD Anderson Cance...

– University of Texas M. D. Anderson Cancer Center

'Explosive Growth’ of Interventional Oncology Prompts Formation of New Society

The board of directors for World Conference on Interventional Oncology, a nonprofit association that supports and promotes the field, has established a society to further its mission.

– Yale Cancer Center


UAB to Bring Proton Therapy for Advanced Cancer Treatment to Birmingham

UAB will partner with Proton International to bring proton therapy, one of the most technically advanced forms of cancer-killing radiation, to Alabama. Proton therapy delivers a more precise dose of radiation to a tumor and can avoid damage to health...

– University of Alabama at Birmingham

Higher Education Events

Annual Benefit Basketball Game Helps All New Mexicans

The New Mexico Senate “Lobos” tip off against the House of Representatives “Aggies” on Wednesday, March 1, at Santa Fe High School. The hotly-contested game is a fun event for those on the court, on the bench and in the stands. But everyone k...

– University of New Mexico Comprehensive Cancer Center





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