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Newswise Special Wire
Tuesday, February 28, 2017

Public edition |

Newswise Cancer Research Wire for 28-Feb-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

As Radiation Therapy Declined So Did Second Cancers in Childhood Cancer Survivors

Childhood cancer survivors are living longer. Now research shows they are also less likely to develop second cancers while still young. The decline followed a sharp drop in the use of radiation therapy for treatment of childhood cancers.

– St. Jude Children's Research Hospital

Embargo expired on 28-Feb-2017 at 11:05 ET

Study Finds No Evidence of Common Herpes Type Virus in Aggressive Brain Cancer Tissue

In a rigorous study of tumor tissue collected from 125 patients with aggressive brain cancers, researchers at Johns Hopkins say they have found no evidence of cytomegalovirus (CMV) infection and conclude that a link between the two diseases, as claim...

– Johns Hopkins Medicine

Clinical Cancer Research; P30CA006973

Molecule Stops Fatal Pediatric Brain Tumor

Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. The tumor is always fatal and primarily strikes children under 10 years old.

– Northwestern University

Nature Medicine; RO1NS093079; R35CA197569

Embargo expired on 27-Feb-2017 at 11:00 ET

Genetic Variant of the p53 Gene Linked to Breast Cancer Risk in Premenopausal African American Women

Scientists at The Wistar Institute in collaboration with Roswell Park Cancer Institute found a significant association between a rare genetic variant of the p53 gene present in African American women and their risk of developing breast cancer in prem...

– Wistar Institute

NPJ Breast Cancer

Embargo expired on 27-Feb-2017 at 10:00 ET

Super Resolution Imaging Helps Determine a Stem Cell’s Future

Scientists at Rutgers and other universities have created a new way to identify the state and fate of stem cells earlier than previously possible. Understanding a stem cell’s fate – the type of cell it will eventually become – and how far along...

– Rutgers University

When Cancer Treatments Do More Harm Than Good

Dr. Cary Gross, a professor of medicine and cancer researcher at Yale University School of Medicine discusses his 80-year-old father's diagnosis with Hodgkin’s disease.

– Yale Cancer Center

Professor Susan Baserga Selected as Finalist for the 2017 Connecticut Technology Council Women of Innovation Program

Susan Baserga selected as a finalist for the 2017 Connecticut Technology Council Women of Innovation program

– Yale Cancer Center

Limiting Lung Cancer’s Spread and Growth in the Brain

Led by associate professor of pathology and Yale Cancer Center member Don Nguyen, PhD, the researchers analyzed RNA from patients with disease that was limited to the lungs as well as cancers that had spread.

– Yale Cancer Center

Cancer Research

Matching Up Fruit Flies, Mushroom Toxins and Human Health

Some fruit flies build up tolerance to the toxin α-amanitin; the genetic mechanisms behind this adaptation link to an important metabolic pathway. A team from Michigan Technological University used genome-wide association mapping to draw the connect...

– Michigan Technological University

PLOS ONE, Feb-2017

Scalp Cooling Can Help Some Breast Cancer Patients Retain Hair

Scalp cooling can lessen some chemotherapy-induced hair loss – one of the most devastating hallmarks of cancer – in certain breast cancer patients, according to a new multicenter study from UC San Francisco, Weill Cornell Medicine and three other...

– UCSF Helen Diller Family Comprehensive Cancer Center


Genetic ‘Balance’ May Influence Response to Cancer Treatment

Choosing among cancer treatments increasingly involves determining whether tumor cells harbor specific, mutated “oncogenes” that drive abnormal growth and that may also be especially vulnerable or resistant to particular drugs. But according to a...

– UCSF Helen Diller Family Comprehensive Cancer Center


Mount Sinai Experts Share Tips for Colorectal Cancer Awareness Month This March

Mount Sinai experts are available during March’s Colorectal Cancer Awareness month to discuss prevention, screening options, and risk factors.

Expert Available

– Mount Sinai Health System

Novel ‘Barcode’ Tracking of T Cells in Immunotherapy Patients Identifies Likely Cancer-Killers

A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person’s immune system are best suited to fight cancer. The findings ...

– Fred Hutchinson Cancer Research Center

Science Immunology, Feb 24, 2017

Embargo expired on 24-Feb-2017 at 14:00 ET

A Novel DNA Vaccine Design Improves Chances of Inducing Anti-Tumor Immunity

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets.

– Wistar Institute

Molecular Therapy

New Antiviral Drug Cuts Cytomegalovirus Infection and Improves Survival in Patients Undergoing Donor Stem Cell Transplant

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute has shown that a novel agent can protect against the most common viral infection that patients ...

– Dana-Farber Cancer Institute

Study Reveals PGK1 Enzyme as Therapeutic Target for Deadliest Brain Cancer

Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center....

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 23-Feb-2017 at 12:00 ET

Anti-Aging Gene Identified as a Novel Promising Therapeutic Target for Older Melanoma Patients

Wistar scientists have shown an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the d...

– Wistar Institute

Clinical Cancer Research; RO1 CA174746-01; P01 CA 114046-06; T32 CA 9171-36; P50 CA174523-01; R01-CA1826635

Embargo expired on 23-Feb-2017 at 10:00 ET

Shorter Radiation Use, BRCA Gene News, Staging Endometrial Cancer, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

– Newswise

New Gene Sequencing Software Could Aid in Early Detection, Treatment of Cancer

A research team from the United States and Canada has developed and successfully tested new computational software that determines whether a human DNA sample includes an epigenetic add-on linked to cancer and other illnesses.

– Johns Hopkins University

Nature Methods, Feb-20-2017

University Hospitals Seidman Cancer Center Enrolls First Patient in New National Head and Neck Cancer Study

Story about the first patient enrolled in the new national phase I trial studying the side effects and best dose and schedule of pembrolizumab, an immunotherapy drug, when given together with chemotherapy and radiation therapy following surgery for ...

– University Hospitals Cleveland Medical Center

CAR T Cells More Powerful When Built With CRISPR, MSK Researchers Find

MSK researchers used the genome-editing tool CRISPR to create more potent chimeric antigen receptor (CAR) T cells that don't tire as easily when attacking cancer cells. The unexpected findings were published in the journal Nature on February 22 and u...

– Memorial Sloan Kettering Cancer Center

Nature, February 22 2017

Embargo expired on 22-Feb-2017 at 13:00 ET

Flu Vaccines, Medical Curriculum Tailored to Native Americans, Tackling Heart Disease, and More in the Healthcare News Source

The latest research, features and announcements in healthcare in the Healthcare News Source

– Newswise

Scientists Identify Chain Reaction That Shields Breast Cancer Stem Cells From Chemotherapy

Working with human breast cancer cells and mice, researchers at Johns Hopkins say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem cells after chemotherapy.

– Johns Hopkins Medicine

Cell Reports; W81XWH-12-1-0464

Clinical Practice Guideline Focuses on Molecular Biomarker Testing for Patients with Colorectal Cancer

A new, evidenced-based clinical practice guideline on molecular biomarker testing for patients with colorectal cancer identifies opportunities for improving patient outcomes.

– College of American Pathologists (CAP)

Measuring Patients' Muscles to Predict Chemotherapy Side Effects

UNC Lineberger researchers and colleagues report in the journal Clinical Cancer Research that a measure of muscle mass and muscle quality developed at UNC could potentially help doctors better identify patients at high risk for toxic side effects tha...

– University of North Carolina Health Care System

Clinical Cancer Research, January-2017

The Right Chemistry: Collaborating Across Multiple Disciplines

Researchers at The University of Kansas Cancer Center are collaborating on the “lab-on-a-chip,” a testing platform that captures and performs analysis of various biomarkers, which are actively released by tumor cells into blood. Rather than the u...

– University of Kansas Cancer Center

Gut Bacteria Associated with Cancer Immunotherapy Response in Melanoma

Melanoma patients’ response to a major form of immunotherapy is associated with the diversity and makeup of trillions of potential allies and enemies found in the digestive tract, researchers at The University of Texas MD Anderson Cancer Center rep...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 21-Feb-2017 at 17:00 ET

Penn and Wistar Researchers Find “Sweet Spot” Where Tissue Stiffness Promotes Cancer’s Spread

University of Pennsylvania and Wistar scientists have studied the physical feedback mechanisms between cancer cells and their environment and described how this interplay allows the migration and invasion of tumor cells.

– Wistar Institute

U01CA202177; U54CA193417; U54CA210173; R01EB017753; R01CA174746; K99 CA208012-01; CMMI-1548571; P30CA010815

Hormonal Maintenance Therapy May Improve Survival in Women with Chemo-Resistant Rare Ovarian or Peritoneum Cancer

For women with a rare subtype of epithelial ovarian or peritoneum cancer, known as low-grade serous carcinoma (LGSC), hormone maintenance therapy (HMT) may significantly improve survival, according to a new study from researchers at The University of...

– University of Texas M. D. Anderson Cancer Center

Survivors' Bell Gives Cancer Patients Extra Ring of Hope

A large silver bell hangs on a wooden plaque at the entrance of City of Hope | Antelope Valley’s chemotherapy infusion area.

– City of Hope


Bristol-Myers Squibb Expands International Immuno-Oncology Network (II-ON) With Addition of Columbia University Medical Center and Peter MacCallum Cancer Centre

Bristol-Myers Squibb Company (NYSE:BMY) today announced that Columbia University Medical Center and Peter MacCallum Cancer Centre (Peter Mac) have joined the International Immuno-Oncology Network (II-ON).

– Columbia University Medical Center

WSU/KCI to Conduct Nation's Largest Study of Factors Affecting African Americans with Cancer

The Karmanos Cancer Institute and Wayne State University School of Medicine will launch the nation’s largest study of African American cancer survivors to better understand disproportionately high incidence and mortality from cancer and its impact ...

– Wayne State University Division of Research

National Cancer Institute, CA199240

Embargo expired on 27-Feb-2017 at 10:05 ET

Hedgehog, Cancer, and Zinc

A team of researchers led by Rensselaer Polytechnic Institute will examine the link between zinc deficiency, Hedgehog, and prostate cancer in a new study funded by the National Institutes of Health (NIH).

– Rensselaer Polytechnic Institute (RPI)

Jeffrey A. Drebin, MD, PhD, Named Chairman of the Department of Surgery at Memorial Sloan Kettering Cancer Center

Jeffrey A. Drebin, MD, PhD, has been named the new Chairman of the Department of Surgery at Memorial Sloan Kettering Cancer Center (MSK). Dr. Drebin brings to MSK decades of experience as a world-class surgical oncologist specializing in pancreatico...

– Memorial Sloan Kettering Cancer Center

22 Cancer Care Facilities Receive Outstanding Achievement Award From the ACS Commission on Cancer

The Commission on Cancer (CoC) of the American College of Surgeons (ACS) has granted its year-end 2016 Outstanding Achievement Award to a select group of 22 accredited cancer programs throughout the United States.

– American College of Surgeons (ACS)

11 From Yale Elected to Connecticut Academy of Science and Engineering

The Connecticut Academy of Science and Engineering has elected 24 of the state’s leading experts in science, engineering, and technology to membership in the academy, including 11 new members from Yale.

– Yale Cancer Center

Four Faculty Elected to Connecticut Academy of Science and Engineering

Four Yale School of Medicine researchers have been elected to the prestigious Connecticut Academy of Science and Engineering (CASE).

– Yale Cancer Center

Sheldon M. Feldman M.D. Named Chief, Division of Breast Surgery & Surgical Oncology, and Director of Breast Cancer Services At Montefiore and Einstein

Internationally Renowned Breast Cancer Surgeon and Researcher Joins Prestigious Breast Cancer Program

– Montefiore Health System


CancerLinQ Partners with Premier Radiation Oncology Society

CancerLinQ LLC and the American Society for Radiation Oncology (ASTRO) are partnering to bring radiation oncology expertise to CancerLinQ and improve the care of cancer patients nationwide.

– ASTRO and CancerLinQ LLC





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