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Newswise Special Wire
Tuesday, March 21, 2017

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Newswise Cancer Research Wire for 21-Mar-2017
 

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.



New Insights Into Side Effects Can Help Prostate Cancer Patients Choose Treatments

A new study led by UNC Lineberger Comprehensive Cancer Center researchers identifies distinct patterns of side effects for prostate cancer treatments that patients could use to guide their choices.

– University of North Carolina Health Care System

JAMA, March-2017

Embargo expired on 21-Mar-2017 at 11:00 ET


Active Surveillance Preserves Quality of Life for Prostate Cancer Patients

Faced with the negative quality-of-life effects from surgery and radiation treatments for prostate cancer, low risk patients may instead want to consider active surveillance with their physician, according to a study released Tuesday by the Journal o...

– Vanderbilt University Medical Center

Journal of the American Medical Association

Embargo expired on 21-Mar-2017 at 11:00 ET


New Research Findings: Health Costs for Children with Cancer Are Higher Than for Adolescents, Adults

ISPOR announced the publication of original research estimating the costs of cancer care in children and adolescents in the March issue of Value in Health.

– International Society for Pharmacoeconomics and Outcomes Research (ISPOR)

Value in Health, Mar-2017


Direct Tumor Vaccination Shown to Induce Anti-Tumor Immunity and Increase Survival in a Murine Model of Pancreatic Cancer

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have sho...

– Rutgers Cancer Institute of New Jersey

Society of Surgical Oncology Cancer Symposium, Mar-2017


Tanning Dependence Linked to Other Addictive Behaviors, New Study Finds

Despite the known dangers of exposure to ultraviolet light, many people continue to sunbathe and use indoor tanning beds with some users exhibiting a dependence to tanning. A new study from the Yale School of Public Health finds that such dependence ...

– Yale Cancer Center


Available Now: New Toolkit Encourages Better Communication to Help Prevent Patients from Suffering in Silence Due to Chemotherapy-induced Nausea and Vomiting

The Hematology/Oncology Pharmacy Association (HOPA), in partnership with Eisai Inc. and Helsinn Therapeutics (U.S.), Inc., today announced the launch of the Time to Talk CINV™ toolkit, which is comprised of resources for patients with cancer going ...

– Hematology Oncology Pharmacy Association


Producing Radioisotopes for Medical Imaging and Disease Treatment

Accelerators built to explore the building blocks of matter help to feed the nation's need for certain critical radioisotopes used to diagnose, track, and treat disease.

– Brookhaven National Laboratory


Scientists Find Possible Achilles Heel of Treatment Resistant Cancers

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models. Reporting results March 20 in Nature Medicine, ...

– Cincinnati Children's Hospital Medical Center

Nature Medicine March 20, 2017

Embargo expired on 20-Mar-2017 at 12:00 ET


Pembrolizumab Shows Promise in Treatment of Mesothelioma

Pembrolizumab, an antibody drug already used to treat other forms of cancer, can be effective in the treatment of the most common form of mesothelioma, according to a new study led by investigators from the Perelman School of Medicine at the Universi...

– Perelman School of Medicine at the University of Pennsylvania


Researchers Discover Key to Drug Resistance in Common Breast Cancer Treatment

Scientists from the Florida campus of The Scripps Research Institute (TSRI), the University of California (UC), San Diego and the University of Illinois have found that two immune system molecules may be key to the development of drug resistance in e...

– Scripps Research Institute

R01DK091183; R01DK015556; R01CA17390; P30 DK063491


Gene Editing Technique Helps Find Cancer’s Weak Spots

Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. This is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at...

– University of California San Diego Health Sciences

Nature Methods


Study Unveils Novel Link Between Cell Polarity and Cancer-Associated Inflammation

A new study led by University of Kentucky Markey Cancer researchers and published in the Journal of Cell Science establishes a novel link between cell polarity and cancer-associated inflammation.

– University of Kentucky

Journal of Cell Science


Automatic Palliative Care Consult for Patients with Advanced Cancers Leads to Improved Outcomes

A recent study demonstrated that increased palliative care consultations for patients with advanced cancers is associated with substantial impact on 30-day readmission, administration of chemotherapy following discharge, hospice referral, and use of ...

– Yale Cancer Center

Embargo expired on 17-Mar-2017 at 16:00 ET


Palliative Care Consults for Patients with Advanced Cancers Reduces Hospitalization and Improves Quality of Care

Cancer patients admitted to the hospital with advanced stages of disease who were referred early to palliative care had decreased health care utilization and increased use of support services following discharge, according to a new study led by resea...

– Mount Sinai Health System

Embargo expired on 17-Mar-2017 at 16:00 ET


Penn Researchers Find Patients’ Annual Financial Burden Under Medicare Part D Is “Too Much Too Soon”

A study released today by researchers at the Perelman School of Medicine at the University of Pennsylvania documents the patient out-of-pocket cost burden under Medicare prescription drug plans (known as Medicare Part D) and finds that despite having...

– Perelman School of Medicine at the University of Pennsylvania

The American Journal of Managed Care


Advanced Form of Proton Therapy Shows Promise for Treating Lung Cancer Recurrence

An advanced form of image-guided radiation therapy, known as intensity modulated proton therapy (IMPT), has shown early promise for the treatment of recurrent lung cancer, according to new research from The University of Texas MD Anderson Cancer Cent...

– University of Texas M. D. Anderson Cancer Center


Combination of Radiation and Immune Checkpoint Therapy Holds Potential for Lung Cancer

An emerging approach for cancer treatment seeks to combine radiation therapy with immune checkpoint inhibitors (ICPIs) to more effectively control tumors in the chest with an acceptable risk of severe treatment-related side effects.

– American Society for Radiation Oncology (ASTRO)

Multidisc Thoracic Cancers Symposium, Mar-2017

Embargo expired on 16-Mar-2017 at 11:00 ET


SBRT Offers Curative Option for Lung Cancer Patients Age 80 and Older

Patients in their 80s and 90s who have early stage lung cancer but cannot undergo an operation can be treated safely and effectively with stereotactic body radiation therapy (SBRT), according to research presented today at the 2017 Multidisciplinary ...

– American Society for Radiation Oncology (ASTRO)

Multidisc Thoracic Cancers Symposium Mar-2017

Embargo expired on 16-Mar-2017 at 11:00 ET


Biomarker Blood Test Shows Cancer Recurrence Months Before CT Scans

Results from a prospective clinical trial showed that a blood test looking at specific biomarkers was able to detect recurrences of lung cancer an average of six months before conventional imaging methods found evidence of recurrence.

– American Society for Radiation Oncology (ASTRO)

Multidisc Thoracic Cancers Symposium Mar-2017

Embargo expired on 16-Mar-2017 at 11:00 ET


Racial Disparities Persist in Treatment and Survival of Early Stage Lung Cancer

Analysis of the largest American cancer database indicates that racial disparities persist in the treatment and outcomes of patients diagnosed with stage I non-small cell lung cancer (NSCLC).

– American Society for Radiation Oncology (ASTRO)

Multidisc Thoracic Cancers Symposium Mar-2017

Embargo expired on 16-Mar-2017 at 11:00 ET


Proton Therapy Offers New Treatment Possibility for Recurrent Lung Cancer

A new study offers hope for patients with recurrent lung cancer, who historically have been considered ineligible for curative treatment.

– American Society for Radiation Oncology (ASTRO)

Multidisc Thoracic Cancers Symposium Mar-2017

Embargo expired on 16-Mar-2017 at 11:00 ET


Genetic Profile of Treatment-Resistant Lung Cancer More Variable Than Previously Understood

The genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought.

– American Society for Radiation Oncology (ASTRO)

Multidisc Thoracic Cancers Symposium Mar-2017

Embargo expired on 16-Mar-2017 at 11:00 ET


Prevention and Prediction: Understanding How Lung Cancer Progresses

Treating the brain with a preventative course of radiation may help Small Cell Lung Cancer (SCLC) patients – whose tumors often spread to their brain -- live longer, according to a new study from researchers in the Abramson Cancer Center and Perelm...

– Perelman School of Medicine at the University of Pennsylvania

2017 Multidisciplinary Thoracic Cancers Symposium in San Francisco


How CT Cancer Screening for Longtime Smokers Can Save Lives

Dawn Andersen lost her husband to lung cancer, and as a longtime smoker herself, she also was at high risk for the disease. So Loyola Medicine pulmonologist Sean Forsythe, MD, recommended Mrs. Andersen undergo a CT lung cancer screening test, which h...

– Loyola University Health System


Prostate Cancer Clinical Trial Shows Treating with Precision Radiotherapy Reduces Course of Treatment by 50%

An Ontario-led international clinical trial with 1,206 men with localized prostate cancer shows that compressing radiation treatments into four weeks from eight delivers similar outcomes.

– University Health Network (UHN)

Journal of Clinical Oncology, March-2017


Scripps Florida Scientists Develop New Drug Delivery Method for Cancer Therapy

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

– Scripps Research Institute

U01 CA174844; R01 CA181258


Bioinformatics Computer Model Predicts Deadliest Lung Cancers

After evaluating more than 900 differences in the shape and structure of cancer cells, UT Southwestern Medical Center researchers developed a computer model able to predict the most deadly lung cancers based on a fraction of those features.

– UT Southwestern Medical Center

Journal of Thoracic Oncology, March 2017


Updated Data on SBRT Radiation for NSCLC Lung Cancer Confirm Benefits of ‘One and Done’ Approach

Collaborative study with Cleveland Clinic & SUNY Upstate Medical University shows that single high-dose SBRT treatment is as effective as three doses in patients with non-small cell lung cancer

– Roswell Park Cancer Institute

Multidisciplinary Thoracic Cancers Symposium 2017


Yale Study Published in JNCCN Uncovers Racial Disparities in Treatment of Women with Breast Cancer

The study, “Racial and Ethnic Disparities in Oncotype Dx™ Test Receipt in a State-Wide Population-Based Study,” led by Cary P. Gross, MD, Yale University School of Medicine and a member of Yale Cancer Center, is published in the March issue of ...

– Yale Cancer Center


AACI Strongly Opposes President’s Cuts to NIH in Fiscal Year 2018 “Skinny Budget”

The Association of American Cancer Institutes opposes President Donald Trump’s budget recommendation to reduce funding to the National Institutes of Health by $6 billion, including a cut of nearly $1 billion for the National Cancer Institute.

– Association of American Cancer Institutes (AACI)


Fat Cells Step in to Help Liver During Fasting

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

– UT Southwestern Medical Center

Science-Mar-2017


Dana-Farber Faculty to Present Abstracts at 2017 AACR Annual Meeting April 1-5, 2017

A summary of a select abstracts by Dana-Farber researchers being presented at 2017 AACR Annual Meeting in April

– Dana-Farber Cancer Institute


New Supportive Care Resources from NCCN Help Patients with Cancer Confront Distress

New NCCN Guidelines for Patients®: Distress available on NCCN.org/patients

– National Comprehensive Cancer Network® (NCCN®)


New Driver, Target in Advanced Mucosal Melanoma

A University of Colorado Cancer Center study published March 15, 2017 in the journal Melanoma Research uses the unique resource of over 600 melanoma samples collected at the university to demonstrate, for the first time, novel mutations involved in m...

– University of Colorado Cancer Center

Melanoma Research; NIH P30CA046934

Embargo expired on 15-Mar-2017 at 14:00 ET


Glioblastoma Clinical Trial Shows Combined Therapy Extends Life for Patients 65 and Older

Treating older patients who have malignant brain cancer with the chemotherapy drug temozolomide plus a short course of radiation therapy extends survival by two months compared to treating with radiation alone, show clinical trial results published t...

– University Health Network (UHN)

New England Journal of Medicine, March-2017

Embargo expired on 15-Mar-2017 at 17:00 ET


European Opinion on Glyphosate Greeted with Concern

Health and cancer groups have reacted with disappointment to the opinion from the European Chemicals Agency (ECHA) today that glyphosate is not a carcinogen. They say it is seen as a setback for efforts to prevent cancer through reduction to exposure...

– Health and Environment Alliance (HEAL)


Yale Study Published in JNCCN Uncovers Racial Disparities in Treatment of Women with Breast Cancer

Researchers at Yale Cancer Center/Smilow Cancer Hospital found that black and Hispanic women in Connecticut are significantly less likely to undergo gene expression profiling than white women.

– National Comprehensive Cancer Network® (NCCN®)


New Liver Cancer Program Launches at Smilow Cancer Hospital

In the last 10 years there has been a constant growth in the number of patient with primary liver cancer treated at Yale New Haven Hospital and at Smilow Cancer Hospital. Smilow is one of the few medical center able to offer to patients with primary ...

– Yale Cancer Center


New Alternative to Colonoscopy Is as Easy as Swallowing a Pill

The patient ingests a capsule containing two miniature cameras on either end. As the capsule travels through the digestive tract, it captures images and wirelessly transmits them to a recorder the patient wears on a belt.

– Loyola University Health System


Exact Replication of Cancer Studies May Speed Development of Improved Cancer Drugs

In response to rising concern that many published scientific results may be false, the Reproducibility Project: Cancer Biology set out to replicate findings from the 50 most cited cancer studies from 2010–2012. A perspective in AACC’s Clinical Ch...

Expert Available

– American Association for Clinical Chemistry (AACC)

Clinical Chemistry, Mar-2017


Malaria Vaccine Trial, Sickle Cell and Kidney Failure, Zika and the Heart, and More in the Public Health News Source

The latest research, experts and features in Public Health in the Public Health News Source

– Newswise


Announcements


Sanford Burnham Prebys Scientist Joins Forces with Rady Children's for Genomic Medicine to Fight Childhood Brain Cancer

Rady Children’s Institute for Genomic Medicine (RCIGM) announced that Robert Wechsler-Reya, Ph.D., has been named program director for the Joseph Clayes III Research Center for Neuro-Oncology and Genomics at RCIGM. Wechsler-Reya, a professor at San...

– Sanford Burnham Prebys Medical Discovery Institute

Embargo expired on 20-Mar-2017 at 11:00 ET


Capitol Hill Educational Briefing Set for March 28

AACI will host an educational briefing to introduce the 115th Congress, staff, and Hill veterans, to academic cancer centers and highlight the role they play in pursuit of 21st Century Cures.

– Association of American Cancer Institutes (AACI)


MD Anderson Celebrates the Mission of Kick Butts Day

As an institution devoted to eliminating cancer, The University of Texas MD Anderson Cancer Center proudly supports the mission of Kick Butts Day to prevent tobacco use in our nation’s children. Organized by the Campaign for Tobacco-Free Kids (CTFK...

– University of Texas M. D. Anderson Cancer Center


William Small, Jr., MD, Editor of New Edition of Classic Radiation Oncology Textbook

William Small, Jr., MD, chair of Loyola Medicine’s radiation oncology department, is editor of a revised third edition of a classic reference in radiation oncology.

– Loyola University Health System


Expert Pitch


Racial Disparities in Genetic Testing of Women with Breast Cancer

– Yale Cancer Center


Health Experts Available to Discuss President Trump’s Proposed NIH Budget Cuts

– West Virginia University


Roy S. Herbst, MD, PhD, on Lung Cancer With Immune Checkpoints: Promising Combinations

– Yale Cancer Center


Dr. Anees Chagpar on Novel Agents for Neoadjuvant TNBC Treatment

– Yale Cancer Center

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