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Newswise Special Wire
Tuesday, May 9, 2017

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Newswise Cancer Research Wire for 09-May-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

Researchers Uncover Key Role for MicroRNA in Inflammatory Bowel Disease

An international team of researchers has discovered that a microRNA produced by certain white blood cells can prevent excessive inflammation in the intestine. The study, “Myeloid-derived miR-223 regulates intestinal inflammation via repression of t...

– The Rockefeller University Press

Journal of Experimental Medicine, June 2017; K01DK106315; CCFA grant 3760; DK097075; HL098294; POI-HL114457; R01-DK082509; R01-HL109233; R01-DK109574...

Embargo expired on 09-May-2017 at 09:00 ET

UCLA Researchers Design Process to Better Understand How Advanced Melanoma Adapts to Immunotherapy

A new study by scientists at the UCLA Jonsson Comprehensive Cancer Center could be a significant step toward understanding how certain cases of advanced melanoma shield themselves from pembrolizumab, the FDA-approved treatment that harnesses the immu...

– University of California, Los Angeles (UCLA), Health Sciences

Stereotactic Partial Breast Radiation Lowers Number of Treatments to Five

UT Southwestern Medical Center researchers found in a recent phase one clinical trial that stereotactic partial breast radiation was as safe as traditional radiation but decreased treatment time from six weeks to just days.

– UT Southwestern Medical Center

International Journal of Radiation Oncology, Biology and Physics-2017

First-In-Human Clinical Trial Aims to Extend Remission for Children and Young Adults With Leukemia Treated With T-Cell Immunotherapy

After phase 1 results of Seattle Children’s Pediatric Leukemia Adoptive Therapy (PLAT-02) trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) into c...

– Seattle Children's Hospital

Cancer Cells Shown to Co-Opt DNA “Repair Crew”

In experiments with human colon cancer cells and mice, a team led by scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer arises when a normal part of cells' machinery generally used to repair DNA damage is diverted...

– Johns Hopkins Medicine

Cancer Cell; RO1ES011858, NO.81522031, NO.81272652

Embargo expired on 08-May-2017 at 12:00 ET

How Cancer Turns a Good-Guy Protein Into a Double Agent

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein become...

– University of Maryland School of Medicine

Embargo expired on 08-May-2017 at 12:00 ET

Penn Study Identifies New Target to Fight Prostate, Lung Cancer

A newly identified molecular chain of events in a mouse model of prostate cancer highlights novel targets to treat it and other cancers. A Penn team discovered that the overexpression of a protein called PKCε with the loss of the tumor suppressor Pt...

– Perelman School of Medicine at the University of Pennsylvania

R01-CA089202, R01-CA189765, R01-CA196232

Poor Overall Environmental Quality Linked to Elevated Cancer Rates

Nationwide, counties with the poorest quality across five domains – air, water, land, the built environment and sociodemographic – had the highest incidence of cancer, according to a new study published in the journal Cancer.

– University of Illinois at Chicago


Fighting Cancer: New Microscopic Technique Could Help Detect, Diagnose Metastatic Melanomas

The fight against skin cancer just got a new weapon. For years, melanoma researchers have studied samples that were considered uniform in size and color, making them easier to examine by more conventional means. But melanomas don’t always come in t...

– University of Missouri Health


Landmark Analysis From Memorial Sloan Kettering Reveals Genomic Tumor Sequence of More Than 10,000 Cancer Patients Using MSK-IMPACT™

Memorial Sloan Kettering (MSK) has reached a major milestone in bringing personalized treatments to more cancer patients. Michael Berger, PhD, Ahmet Zehir, PhD, and colleagues have reported an in-depth analysis of the first 10,336 patients whose tumo...

– Memorial Sloan Kettering Cancer Center

Nature Medicine

Uninsured Breast Cancer Patients More Likely to Die

Uninsured women with breast cancer were nearly 2.6 times more likely to have a late-stage diagnosis than cancer patients who were insured, finds a new study from the Brown School at Washington University in St. Louis.

– Washington University in St. Louis


Gift to Speed Discoveries to Patients

Blavatnik fund to speed discoveries to patients

– Yale Cancer Center

Hands-on Chemistry Course Has Students Taking on Rare Cancers

With graduation just around the corner, a few undergraduates finishing up a hands-on chemistry course will be taking very useful skills with them to the next stop on their career and education path. With robotic arms and moving trays to run automated...

– Perelman School of Medicine at the University of Pennsylvania

World Hand Hygiene Day, Young Adult Smokers, Synthetic Marijuana, and More in the Public Health News Source

The latest research, experts and features in Public Health in the Public Health News Source

– Newswise

Backed by Dana-Farber Research, FDA Approves New AML Drug

A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.

– Dana-Farber Cancer Institute

Coding, Machines May Decrease False Positives in Breast Cancer Screenings

Machine learning (or coding) could help reduce false positives from mammography screening, according to an article study published online in the May 4, 2017 issue of the Journal of the American Medical Association (JAMA) Oncology. The national coding...

– Seattle Cancer Care Alliance

JAMA Oncology

Research Supports Use of Enhanced Recovery Approaches in More Abdominal Surgeries

A new meta-analysis by a team from Roswell Park Cancer Institute demonstrates that Enhanced Recovery After Surgery (ERAS) programs are effective in patients requiring many abdominal and pelvic operations, not just those undergoing colorectal surgerie...

– Roswell Park Cancer Institute

Annals of Surgery

Large Data Set Brings Precision to Breast Cancer Diagnosis and Care

Although the odds of developing breast cancer are nearly identical for black and white women, black women are 42 percent more likely to die from the disease. A large, multi-institutional study, published on-line May 4, 2017, in JAMA Oncology, explore...

– University of Chicago Medical Center

JAMA Oncology, May 4, 2017

Embargo expired on 04-May-2017 at 11:00 ET

Scientists Solve Major Cancer Protein Conundrum

Despite intense research, there’s been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, ...

– Scripps Research Institute

NS077952; CA124495; Children’s Tumor Foundation

Yale Researcher Gets $792,000 Grant From Cancer Society

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University.

– Yale Cancer Center

Advanced Prostate Cancer Treatment Failure Due to Cell Reprogramming

Researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy. The findings, based on a study in mice, could help to determine which patients ...

– Columbia University Medical Center

Cancer Discovery, May 4, 2017

Mysterious Molecule’s Function in Skin Cancer Identified

SBP researcher Ranjan Perera uncovered the M.O. of a mysterious lncRNA molecule called SPRIGHTLY that acts as a hub for cancer-related genes in the nucleus. The study identified “major” RNA binding partners – genes already implicated in a varie...

– Sanford Burnham Prebys Medical Discovery Institute

CA165184; 5P30CA030199; DP5 OD012160

Embargo expired on 03-May-2017 at 14:00 ET

Making the Numbers Work: Researchers Use Math to Develop Personalized Chemo Treatments

A team of Florida State University researchers is using mathematical modeling to find the best and most effective chemotherapy treatments for cancer patients.

– Florida State University

St. Jude Maps Genome Organization to Link Retinal Development and Retinoblastoma

A map of the genome organization and DNA modifications that control growth of normal and cancerous retinal cells offers scientists a new path to understanding retinoblastoma and degenerative retinal diseases.

– St. Jude Children's Research Hospital

Neuron, May 2017

Report: Younger Women Battling Breast Cancer Face More Aggressive Diagnoses, and Therefore, More Significant Treatment Burden

As the nation struggles with soaring health care costs, a new report by RTI International shows that younger women diagnosed with breast cancer face a significant treatment burden.

– RTI International

Breast Cancer Research and Treatment

At Last, a Clue to Where Cancer Metastases Are Born

Scientists at The Scripps Research Institute (TSRI) have discovered why some cancers may reoccur after years in remission.

– Scripps Research Institute

Cell Reports, April 2017; R01CA157792; R01CA105412; R01CA129484

Gene Sequencing at Yale Finding Personalized Root of Disease

On Monday, the Yale School of Medicine, partnering with Yale New Haven Hospital, took the next step toward personalized medicine, cutting the ribbon on its Center for Genome Analysis on Yale’s West Campus.

– Yale Cancer Center

One and Done: Michigan Man Benefits From Prostate Cancer Research Program

Prostate HDR brachytherapy typically takes two to three hours. Patients usually go home from the hospital the same day. In contrast to permanent seed, or low-dose-rate brachytherapy, with HDR, no radioactive material is left inside the patient after ...

– Beaumont Health

International Journal of Radiation Oncology


New Lung Cancer Center at NYU Langone Welcomes Renowned Thoracic Surgeon as Its Director

Robert J. Cerfolio, MD – whose innovations in robotics have led to practice-changing advances in lung cancer surgery – will join NYU Langone as chief of clinical thoracic surgery. He also will become the first director of the Lung Cancer Center a...

– NYU Langone Medical Center

Andrew Sabin Family Fellows to Receive $100,000 in Research Funding

The University of Texas MD Anderson Cancer Center named eight innovative researchers to the second annual class of Andrew Sabin Family Fellows at a luncheon today attended by Andrew Sabin, of East Hampton, New York, and representatives of the Andrew ...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 08-May-2017 at 09:00 ET

Georgia State Researcher Gets $2.3 Million Grant to Study How to Reduce Tumor Growth in Lung Cancer

Dr. Ming-Hui Zou, director of the Center for Molecular & Translational Medicine and a Georgia Research Alliance Eminent Scholar in Molecular Medicine, has received a five-year, $2.3 million federal grant to study how to reduce tumor growth in lung ca...

– Georgia State University

New $21 Million Gift Puts Basser Center for BRCA at the Forefront of Advancements for Patients At Risk of Inherited Cancers

A new $21 million gift to the Basser Center for BRCA at the Abramson Cancer Center of the University of Pennsylvania from alumni Mindy and Jon Gray will cement and propel Penn’s preeminence as a leader in research to improve treatment and preventio...

– Perelman School of Medicine at the University of Pennsylvania

Embargo expired on 04-May-2017 at 10:00 ET

Chicago Radiological Society Gives Highest Honor to Loyola Radiation Oncologist

Loyola Medicine radiation oncologist Edward Melian, MD, has received the Chicago Radiological Society’s 2017 Distinguished Service Award, the highest honor the society bestows on members.

– Loyola University Health System

TTUHSC El Paso Breaks Ground on $83 Million Medical Sciences Building

Texas Tech University Health Sciences Center El Paso (TTUHSC El Paso) officially broke ground on the Medical Sciences Building (MSB) II, an $83 million, 219,900-square-foot facility.

– Texas Tech University Health Sciences Center El Paso

University of North Florida Receives Platinum-Level Skin Smart Campus Designation

The University of North Florida was awarded the platinum-level Skin Smart Campus designation by the National Council on Skin Cancer Prevention and will implement a campus-wide skin cancer prevention initiative this month as part of National Skin Canc...

– University of North Florida

UAB Expands Cancer Navigation Program Nationally with Guideway Care

UAB and Guideway Care have announced a partnership to expand the reach of UAB’s cancer navigation program to patients nationally to help guide them through the complex challenges and barriers that cancer treatment presents.

– University of Alabama at Birmingham

Higher Education Events

The Art of the Scarf: Free Workshop Helps Cancer Patients and Survivors

The free Art of the Scarf workshop to teaches women how to tie, wrap or twist scarves for headwear. The workshop at The UNM Cancer Center is open to all patients, survivors with long-term hair loss, and caregivers. It is offered free of charge but re...

– University of New Mexico Comprehensive Cancer Center

“Polly’s Run” Raises Awareness, Money and Hope to Fight Pancreatic Cancer

The eighth annual “Polly’s Run” raises awareness for pancreatic cancer, honors pancreatic cancer survivors and all those who face the disease, and raises money for pancreatic cancer research. Albuquerque Pet Memorial Services sponsors the event...

– University of New Mexico Comprehensive Cancer Center


UAB Spinoff Targets Cancer with Drug-Resistant Immunotherapy, a Novel Approach to Fighting Tumors

The University of Alabama at Birmingham and two partner institutions have received a European patent for their novel approach to fighting cancer, an approach that is led by the UAB spinoff biopharmaceutical company Incysus Ltd.

– University of Alabama at Birmingham

Expert Pitch

Yale Expert Discusses Immuno-Oncology (I-O) Agents for Cancers

– Yale Cancer Center





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