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Newswise Special Wire
Tuesday, June 13, 2017

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Newswise Cancer Research Wire for 13-Jun-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

International Study Identifies New Genetic Risk Factors for Testicular Cancer

Peter Kanetsky, Ph.D., M.P.H., chair of the Cancer Epidemiology Department at Moffitt Cancer Center, and colleagues from the International TEsticular CAncer Consortium (TECAC), launched a large analysis of five major testicular cancer studies to inve...

– Moffitt Cancer Center

Nature Genetics

Strategy of Hope: Patients Try Creative Approaches to Fight Brain Cancer

Dennis Kothmann jots several numbers on a clipboard then pauses, his pen frozen on the last figure. His eyebrows furrow and he quietly mouths a calculation.

– UT Southwestern Medical Center

Infant Sun Protection: How Parents Can Keep Their Baby Safe

Skin cancer is the most common cancer in the United States, and it only takes one blistering sunburn during childhood or adolescence to nearly double a person’s chance of developing melanoma, the deadliest form of skin cancer, later in life. This i...

– American Academy of Dermatology

ASTRO Issues Guideline for Use of Stereotactic Radiation in Early-Stage Lung Cancer

The American Society for Radiation Oncology (ASTRO) issued a new clinical guideline for the use of stereotactic body radiation therapy (SBRT) in early-stage lung cancer today.

– American Society for Radiation Oncology (ASTRO)

Practical Radiation Oncology

Embargo expired on 12-Jun-2017 at 09:00 ET

HPV Vaccine Could Drastically Reduce Cervical and Other Cancers Globally

The latest HPV vaccine could prevent most HPV infections — and millions of cancers — worldwide, according to an article by Cosette Wheeler, PhD, and her collaborators. The article describing the HPV vaccine and strategies to overcome issues with...

– University of New Mexico Comprehensive Cancer Center

ASCO Online Daily News

Embargo expired on 12-Jun-2017 at 06:05 ET

New Process May Lead to Vaccine for Schistosomiasis

Cornell and Ludwig Institute for Cancer Research scientists have developed a way to produce a protein antigen that may be useful as vaccine for schistosomiasis – a parasitic disease that infects millions of people, mostly in tropical and subtropica...

– Cornell University

Study Sheds New Light on Inherited Testicular Cancer Risk

An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors. The findings, which researchers call a success story for genome mapping, could h...

– Perelman School of Medicine at the University of Pennsylvania

NCI 02-C-0178; NCT-00039598; U01CA164947; CA114478

Moffitt Researchers Identify a Novel Inhibitor That Overcomes the Drug Resistance in Prostate Cancer

In a study published today in Cancer Cell, Moffitt Cancer Center researchers report that a newly discovered epigenetic mechanism can lead to the development of castration-resistant prostate cancer. They identified a novel drug that targets this epige...

– Moffitt Cancer Center

Cancer Cell

Metastatic Breast Cancer Cells Use Hedgehog to ‘Evilize’ Docile Neighbors

University of Colorado Cancer Center study pinpoints promising link in the chain of hedgehog signaling that, when broken, could reduce the metastatic potential of breast cancer.

– University of Colorado Cancer Center

Nature Communications; NIH P30CA046934; R01CA127857; P50 SPORE CA50183; U54CA149196; R01CA095277

Lab on a Chip Could Monitor Health, Germs and Pollutants

Imagine wearing a device that continuously analyzes your sweat or blood for different types of biomarkers, such as proteins that show you may have breast cancer or lung cancer. Rutgers engineers have invented biosensor technology – known as a lab o...

– Rutgers University

Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the...

– University of North Carolina Health Care System


Study: New Approach to Destroying Deadly Brain Tumors

A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study from UT Southwestern Medical Center.

– UT Southwestern Medical Center

Nature Neuroscience, June 2017

Caregiver, Cancer Survivor and Author: City of Hope Nurse Christine Magnus Moore

As a nurse coordinator in City of Hope’s Department of Hematology & Hematopoietic Cell Transplantation, Christine Magnus Moore, R.N., B.S.N., has cared for patients going through the most challenging circumstances one can imagine.

– City of Hope

Flaws in a Tumor's Genetic Mending Kit Drive Treatment Response to Immunotherapy

In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunother...

– Johns Hopkins Medicine

Science; P50CA062924, P30CA006973, CA163672, CA43460, CA203891, CA67941, CA16058CA57345

New Cancer Drug Tested in Mice May Benefit Certain Leukemia Patients

Almost 6,000 new cases of acute lymphoblastic leukemia, or ALL, are expected to be diagnosed this year in the United States. Scientists have found up to 30 percent of adult ALL patients have what’s called a Philadelphia chromosome, where two segmen...

– University of Utah Health

Leukemia; CA188520

UAMS Researchers Kill Cancer Cells Using Nanobubble Spaser as the World’s Smallest Laser

A University of Arkansas for Medical Sciences (UAMS) research team led by Vladimir Zharov, Ph.D., D.Sc., has demonstrated the ability to kill single cancer cells using the world’s smallest laser.

– University of Arkansas for Medical Sciences

Researching Radiosensitizers, a New Class of Drugs That Would Make Tumors More Vulnerable to Radiation Therapy

Two out of three cancer patients are treated with radiation, but the therapy often fails to wipe out the tumor or slow its growth. Southern Research is working to develop a new class of drugs that will help the radiation deliver a more powerful punch...

– Southern Research

Treatment Advances Help Improve Childhood Cancer Survival in New Jersey

The latest in childhood cancer statistics in New Jersey show significant declines in mortality rates for white, black and Hispanic children from 1979 to 2013. A Rutgers Cancer Institute of New Jersey expert says this improvement in survival can be at...

– Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute Experts Highlight Testicular Cancer Awareness During Men's Health Month

While the risk of developing testicular cancer is low, every man should understand some basic facts about this disease. Rutgers Cancer Institute of New Jersey experts share more about the disease, which is the most common malignancy among men ages 15...

– Rutgers Cancer Institute of New Jersey

Breast Cancer Special Report in NEJM Shows Why Women 40-49 Should Get Regular Mammograms

Lannin and Wang, published June 8 in the New England Journal of Medicine, showed that younger women of screening age are more likely to develop aggressive breast cancers than older women. This added risk reinforces why women should start annual mammo...

– American College of Radiology (ACR)

Embargo expired on 07-Jun-2017 at 17:00 ET

Innovative Therapy Strategy for Pancreatic Cancer Uses Engineered Exosomes Targeting Mutated KRAS Gene

Genetic manipulation of exosomes, virus-sized particles released by all cells, may offer a new therapeutic approach to treating pancreatic cancer, according to a study at The University of Texas MD Anderson Cancer Center.

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 07-Jun-2017 at 13:00 ET

Encouraging Updated Findings of Pembrolizumab in Gastric and GEJ Cancer Presented Prior to FDA Decision

In updated findings from the KEYNOTE-059 trial of pembrolizumab in advanced gastric or gastroesophageal junction (GEJ) cancer, the PD-1 inhibitor maintained signs of its clinical benefit in this patient population.

– Yale Cancer Center

Regular Brisk Walk May Help Reduce the Risk of Dying From Cancer: Study

Walking is probably the simplest, easiest and the most inexpensive way to remain fit. Experts link a bevy of health benefits with regular walking.

– Yale Cancer Center

SLU Researcher Finds Cause and Possible Relief of Cancer Bone Pain

Saint Louis University scientist Daniela Salvemini, Ph.D., reports discovering a key pathway that drives cancer-related bone pain while providing a potential solution with a drug that already is on the market.

– Saint Louis University Medical Center

Review of Appendix Cancer Cases Finds Over Diagnosis

Lesions of the appendix are being over diagnosed as invasive cancer, report University of California San Diego School of Medicine researchers in a paper published June 7 in the journal <i>PLOS ONE</i>.

– University of California San Diego Health


Roswell Park’s Dr. Kunle Odunsi Gives Update on Ovarian Cancer Immunotherapy Study at ASCO Annual Meeting

Dr. Kunle Odunsi of Roswell Park Cancer Institute presented an update about an ongoing clinical trial involving T-cell engineering to treat advanced ovarian cancer at the ASCO Annual Meeting in Chicago.

– Roswell Park Cancer Institute

Roswell Park-Led Research Updates Data on Lenalidomide Maintenance for Patients with Multiple Myeloma

Dr. Philip McCarthy of Roswell Park Cancer Institute presents updated findings on CALGB/ECOG 100104 study of lenalidomide maintenance therapy for multiple myeloma, adjusting data to account for crossover effect.

– Roswell Park Cancer Institute

ASCO Annual Meeting, June 2017

Predictive Tool Developed by Roswell Park-OmniSeq Team Accurately Reflects Response to Checkpoint Inhibition

Roswell Park and OmniSeq report that a custom algorithm they developed based on a 54-gene signature accurately predicted response to anti-PD-L1 treatment in 90% of the cases they analyzed.

– Roswell Park Cancer Institute

ASCO Annual Meeting 2017

Cancer Cells Send Signals Boosting Survival and Drug Resistance in Other Cancer Cells

Researchers at University of California San Diego School of Medicine report that cancer cells appear to communicate to other cancer cells, activating an internal mechanism that boosts resistance to common chemotherapies and promotes tumor survival. ...

– University of California San Diego Health

Science Signalling

NUS Researchers Identify Potential Target for Treatment of Aggressive Brain Cancer

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered that the BCL6 protein could potentially be used as a marker to predict clinical outcomes of patients suffering from Glioblastoma Multif...

– National University of Singapore

Proceedings of the National Academy of Sciences of the United States of America


Brownson Receives $2.9 Million Grant to Boost Physical Activity in Rural Communities

Ross Brownson, the Bernard Becker Professor and director of the Prevent Research Center at the Brown School at Washington University in St. Louis, has been awarded a $2.9 million grant from National Institutes of Health/National Cancer Institute for ...

– Washington University in St. Louis

Kathy Albain, MD, Receives Endowed Chair to Fund Oncology Research

Grateful for the life-saving care they received at Loyola Medicine, Peter and Heidi Huizenga have made a generous gift to further oncology research and to honor Kathy Albain, MD, FACP, FASCO.

– Loyola University Health System

Cancer Immunotherapy Researcher Brings Team to Houston Methodist

Houston Methodist is launching the Center for Immunotherapy Research under the leadership of Shu-Hsia Chen, Ph.D., a cancer immunotherapy researcher recruited from Icahn School of Medicine at Mount Sinai.

– Houston Methodist

MD Anderson and Hitachi to Collaborate in Research for Treatment of Oropharyngeal Cancer of the Head and Neck

The University of Texas MD Anderson Cancer Center and Hitachi Healthcare Americas Corporation, have today announced that they have entered into an agreement to collaborate on research for a unique randomized clinical trial comparing the outcomes and ...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 07-Jun-2017 at 09:00 ET

Cancer Research Institute to Bring Together Cancer Patients, Leading Immunotherapy Manufacturers, and Highland Falls Community Members for Second Annual Answer to Cancer Sponsored by Bristol-Myers Squibb

Day-long endurance event starting at the U.S. Military Academy at West Point, NY, focused on cancer immunotherapy research

– Cancer Research Institute


MD Anderson and Convergent R.N.R. Ltd. Establish Alliance to Further Develop New Radiation Technology with Potentially Fewer Side Effects

The University of Texas MD Anderson Cancer Center and Convergent R.N.R. Ltd. (CRnR) today announced a collaboration to further develop new radiation technology aimed at reducing side effects of standard radiation including unwanted radiation to healt...

– University of Texas M. D. Anderson Cancer Center

Embargo expired on 12-Jun-2017 at 07:00 ET

Expert Pitch

Texas A&M Researcher Explores Power Of Hope In Cancer Care

– Texas A&M University

Expert to Speak on Bevacizumab in Advanced Head and Neck Cancer

– Yale Cancer Center





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