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Newswise Special Wire
Tuesday, June 20, 2017

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Newswise Cancer Research Wire for 20-Jun-2017

Cancer Research Wire

Cancer research news for the public and news media. More stories can be found at the Newswise Cancer News Source.

NCCN Guidelines Compliance for Chest CT Reduces False Positives and Decreases Health Care Spending in Breast Cancer, Study Finds

As published in JNCCN, a Siteman Cancer Center study uncovered potential to significantly improve NCCN Guidelines-concordant care in patients with early-stage breast cancer.

– National Comprehensive Cancer Network® (NCCN®)

Tumor Immune Fitness Determines Survival of Lung Cancer Patient

In recent years, immunotherapy, a new form of cancer therapy that rouses the immune system to attack tumor cells, has captivated the public’s imagination. When it works, the results are breathtaking. But more often than not it doesn’t, and scient...

– La Jolla Institute for Allergy and Immunology

Nature Immunology

Embargo expired on 19-Jun-2017 at 11:00 ET

Firefly Gene Illuminates Ability of Optimized CRISPR-Cpf1 to Efficiently Edit Human Genome

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have improved a state-of-the-art gene-editing technology to advance the system’s ability to target, cut and paste genes within human and animal cells—and broadening the way...

– Scripps Research Institute

journal Nature Chemical Biology; R37 AI091476 ; P01 AI100263

Embargo expired on 19-Jun-2017 at 11:00 ET

Study Shows How an Opportunistic Microbe Kills Cancer Cells and Identifies Specialized Vesicles Responsible for Cell Reproduction

New study results show for the first time how dying cells ensure that they will be replaced, and suggests an ingenious, related new approach to shrinking cancerous tumors. A research team from Rush University Medical Center will publish a new paper t...

– Rush University Medical Center

Embargo expired on 19-Jun-2017 at 12:00 ET

Blue-Ribbon Committee Creates Ultrasound Scoring System for Thyroid Nodules to Reduce Unnecessary Biopsies

National committee creates American College of Radiology ultrasound-based risk stratification system to identify nodules that warrant biopsy or sonographic follow-up, and identify most clinically significant malignancies while reducing the number of ...

– University of Alabama at Birmingham

Indoor Tanning Still Accessible to Young People—Despite Bans

Despite legislation prohibiting the use of ultraviolet (UV) indoor tanning facilities by minors, one in every five tanning salons in United States where such bans are in place stated over the phone that they would allow an underage caller to do so. ...

– Yale Cancer Center

Surgery and High-Dose SBRT Radiation Can Be Combined to Treat Kidney Cancer, Roswell Park Researchers Show

A new study from Roswell Park Cancer Institute reporting the findings of the first clinical trial to evaluate the immune effects of high-dose radiation therapy followed by surgery in patients with advanced kidney cancer may also set the stage for com...

– Roswell Park Cancer Institute

Clinical Cancer Research; NIH UL1TR001412; NCI NP30CA016056; NCI R01CA140622

Brain Tumors: Still Devastating, but Treatment Has Come a Long Way

A UAB neurosurgeon discusses advances in brain tumor diagnosis and treatment that are bringing renewed hope to the battle against brain cancer.

– University of Alabama at Birmingham

Fred Hutch Study Suggests NSAIDs Improve Survival for Certain Colorectal Cancer Patients

Among long-term colorectal cancer survivors, use of nonsteroidal anti-inflammatory drugs, or NSAIDs, is associated with about a 25 percent reduction in all-cause mortality, according to new research from Fred Hutchinson Cancer Research Center.

– Fred Hutchinson Cancer Research Center

Embargo expired on 15-Jun-2017 at 16:00 ET

Cancer Research Journal Devotes Special Issue to Radiation Therapy and the Elderly

In response to an aging U.S. population and the rise in cancer incidence rates, a new special edition of the International Journal of Radiation Oncology•Biology•Physics (Red Journal) explores trends, challenges and new approaches in treating canc...

– American Society for Radiation Oncology (ASTRO)

International Journal of Radiation Oncology*Biology*Physics

Inhibitor Drug Improves Overall Survival in Older Radioiodine Resistant Thyroid Cancer Patients

The drug lenvatinib can significantly improve overall survival rates in a group of thyroid cancer patients whose disease is resistant to standard radioiodine treatment, according to new research from the Perelman School of Medicine at the University ...

– Perelman School of Medicine at the University of Pennsylvania

Research on Crucial Cutting Enzyme Maps Site of DNA Damage in Leukemias and Other Cancers

Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that cause cancer, including leu...

– Children's Hospital of Philadelphia

Genome Research, online April 6, 2017; CA77683, CA80175, GM033944, ES013508-06

Targeting Immune Cells That Help Tumors Stay Hidden Could Improve Immunotherapy

Researchers have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers. The findings, published in Cell, were made in mice and showed that targeting a sub-population of immune cells called regulat...

– Health Sciences at the University of Pittsburgh

Cell, May 2017

UTSW, UT Advanced Computing Center Share Big-Data Tools in Fight Against Cancer, Infectious Diseases

UT Southwestern scientists who created a powerful analytic weapon in the fight against cancer and infectious diseases are making that tool available for free via a web-based portal.

– UT Southwestern Medical Center

Protein Network Signals Found to Drive Myeloid Leukemias

Researchers have uncovered how mutations in a protein network drive several high-risk leukemias, offering new prospects for novel therapies. An existing drug might be repurposed to treat these leukemias, and the new understanding of the molecular mec...

– Children's Hospital of Philadelphia

HL095675, CA87986, CA105489; Genes and Development, online June 13, 2017

A Closer Look at Hair Products and Breast Cancer Risk

Can use of hair products have an impact on breast cancer risk for women? That is a question explored by investigators from Rutgers Cancer Institute of New Jersey, Rutgers School of Public Health and other colleagues who examined use of hair dyes, hai...

– Rutgers Cancer Institute of New Jersey

Carcinogenesis, June-2017

GW Cancer Center Researchers Look at Resistance to Targeted Therapy in Mantle Cell Lymphoma

A team of cancer researchers at the George Washington University Cancer Center published research looking at the underlying mechanisms of resistance to the drug, Ibrutinib, which is used to treat patients with mantle cell lymphoma.

– George Washington University

Nature Communications

Experimental Drug Co-Developed by Moffitt Cancer Center Researcher Shows Promise

The investigation found that the drug, geranylgeranyltransferase inhibitor GGTI-2418 suppresses a new defective PTEN cancer pathway discovered by Pagano’s group.

– Moffitt Cancer Center

Minimizing the Effects of Radiation Injury

New research could make treatment for gastrointestinal cancers safer.

– University of Kansas Cancer Center

CU Cancer Center Chemoprevention Trial Hopes to Stop Lung Cancer Before It Starts

Ongoing clinical trial by University of Colorado Cancer Center investigators is evaluating the ability of an inhaled form of the pulmonary hypertension drug iloprost to prevent lung cancer.

– University of Colorado Cancer Center

Sharpless Appointment as NCI Director Commended by AACI

The Association of American Cancer Institutes applauds the appointment of Norman “Ned” Sharpless, MD, as the next director of the National Cancer Institute. Dr. Sharpless is an AACI board member and director of the University of North Carolina Li...

– Association of American Cancer Institutes (AACI)

Researchers Show How a Cancer Gene Protects Genome Organization

UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme called Set2 found in virtually all organisms other than bacteria. The basic science finding may have implications for understanding cancer development a...

– University of North Carolina Health Care System

Cell Reports

Discovery by NUS Researchers Improves Understanding of Cellular Ageing and Cancer Development

A team of researchers led by Dr Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which...

– National University of Singapore

EMBO Reports

ARN Releases White Paper to Define the Role of the Rehabilitation Nurse Within Cancer Rehabilitation

As cancer survival rates continue to rise, more and more patients benefit from physical rehab during and after treatment to help maintain and restore function. Rehabilitation nurses look to ARN to help define their role in this arena.

– Association of Rehabilitation Nurses


$2.24M Grant Awarded to Rutgers Cancer Institute of New Jersey Researchers

A $2.24 million competing renewal grant from the National Cancer Institute will support the work of investigators at Rutgers Cancer Institute of New Jersey and Princeton University to learn more about the fuel required for tumor growth. The collabora...

– Rutgers Cancer Institute of New Jersey


Henry Ford Cancer Institute First in World to Install MRI-Guided Radiation Therapy with MRIdian Linac

The Henry Ford Cancer Institute is the first in Michigan – and first in the world – to offer patients an advanced radiation therapy that uses an FDA-approved real-time magnetic resonance imaging and linear accelerator delivery for more precise an...

– Henry Ford Health System

GW Cancer Center Opens Supportive Oncodermatology Clinic

The George Washington University Cancer Center opened a Supportive Oncodermatology Clinic, which will support patients through side effects of cancer treatment such as hair loss. This clinic is the only one of its kind in the Washington, D.C. region,...

– George Washington University

UVA Honored as Center of Excellence for Bone Marrow Cancer

University of Virginia Cancer Center has earned recognition as a national center of excellence for its care of patients with myelodysplastic syndrome (MDS), a cancer of the bone marrow that often leads to leukemia.

– University of Virginia Health System

All Slots for Prestigious Neuro-Oncology Fellowship Filled by UAMS Residents

Two residents from the University of Arkansas for Medical Sciences (UAMS) have been selected for a prestigious fellowship in neuro-oncology administered jointly by the Johns Hopkins University School of Medicine and the National Institutes of Health ...

– University of Arkansas for Medical Sciences

Wayne State University/Karmanos Cancer Institute Research Team Receive NIH Funding to Expand Imaging Technology to Guide Cancer Treatment

A team of Wayne State University and Barbara Ann Karmanos Cancer Institute researchers recently received funding from the National Cancer Institute of the National Institutes of Health to expand the use of Positron Emission Tomography (PET) in cancer...

– Wayne State University Division of Research

National Cancer Institute, CA216648

Expert Pitch

Why Are Scientists Questioning the Safety of Triclosan and Triclocarban?

– Arizona State University (ASU)

Embargo expired on 20-Jun-2017 at 06:00 ET

Talking Breast Cancer for Men’s Health Awareness Week

– University of California San Diego Health





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